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The map label for this gene is dinP [H]

Identifier: 227082411

GI number: 227082411

Start: 2379345

End: 2380427

Strand: Reverse

Name: dinP [H]

Synonym: VCM66_2210

Alternate gene names: 227082411

Gene position: 2380427-2379345 (Counterclockwise)

Preceding gene: 227082412

Following gene: 227082410

Centisome position: 82.3

GC content: 47.0

Gene sequence:

>1083_bases
ATGCAAGACAGAATTCGTAAAATCATCCATGTCGATATGGACTGCTTTTTCGCTGCCGTTGAAATGCGGGATAACCCTGC
GTATCGAGAGATAGCACTGGCCGTGGGCGGACATGAAAAGCAGCGTGGAGTGATCAGTACATGCAACTATCAGGCGCGCA
AATTTGGCGTTCGTTCTGCTATGCCTACCGCTCAGGCATTAAAACTCTGCCCACAACTGCATGTCGTCCCGGGGCGGATG
TCTGTCTACAAAAGTGTTTCTCAACAAATCCAAACTATTTTTCAGCGTTATACCTCGTTGATTGAGCCTCTTTCACTTGA
TGAGGCCTATCTTGATGTCAGTGAATCGACTGCCTATCAAGGTAGTGCGACCTTAATTGCTCAAGCGATTCGACGTGATA
TCTGGCAAGAGTTGAATTTAACGGCGTCCGCTGGTGTTGCGCCGATCAAGTTTCTTGCAAAAGTTGCGTCCGACTTAAAT
AAACCTGATGGCTTGTATGTGGTGACGCCTGACAAAGTTCAGGAGATGGTCGATAGTTTGCCGCTGGAAAAGATTCCGGG
TGTTGGCAAAGTGGCGTTAGAAAAGCTGCATCAAGCCGGTCTTTATGTCGGAGCGGATGTAAGGCGAGCGGACTATCGCA
AGTTACTGCATCAATTTGGGCGTTTAGGTGCTTCTTTGTGGAAAAAAAGTCACGGCATTGATGAACGTGAAGTGGTGACT
GAGCGCGAACGAAAATCTGTCGGTGTGGAGTACACCTTTAGCCAAAACATTTCGACGTTTCAGGAGTGTTGGCAAGTGAT
TGAACAGAAATTGTATCCGGAGCTAGATGCTCGTTTGAGTCGGGCTCACCCACAGCGAGGCATTATTAAACAAGGCATTA
AAGTGAAATTTGCTGATTTCCAACAGACAACCATTGAGCATGTTCACCCTGCATTAGAGCTCGACTACTTCCACGAGCTG
TTAGAGCAAGTGTTAACTCGCCAGCAAGGACGAGAAATTCGCTTACTTGGTTTAAGTGTCATGCTTAAGCCGGAATTGCA
GATGAAACAGCTATCGATGTTTCCGAGTGATGGATGGCAATAG

Upstream 100 bases:

>100_bases
ATCGCATCAAAAAGCTCGCTCCGGCGGGCTTTTTGTTTATCAGACTTTCCTTATCGATGGCTTATTATTATACTGTTTAT
GTATACAGTATTGGTGGGCT

Downstream 100 bases:

>100_bases
GCCGATGCCTCTCTTAAAACAGACATCATGGAGTGGGGTGATAAAGAGCGTTATCCTTTCGTCGCCTAATGCAAATCGTT
TGGTATAGTGTGTTTGTTAT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSAMPTAQALKLCPQLHVVPGRM
SVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQGSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLN
KPDGLYVVTPDKVQEMVDSLPLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVT
ERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADFQQTTIEHVHPALELDYFHEL
LEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ

Sequences:

>Translated_360_residues
MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSAMPTAQALKLCPQLHVVPGRM
SVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQGSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLN
KPDGLYVVTPDKVQEMVDSLPLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVT
ERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADFQQTTIEHVHPALELDYFHEL
LEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ
>Mature_360_residues
MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSAMPTAQALKLCPQLHVVPGRM
SVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQGSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLN
KPDGLYVVTPDKVQEMVDSLPLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVT
ERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADFQQTTIEHVHPALELDYFHEL
LEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=214, Percent_Identity=34.1121495327103, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI84043967, Length=214, Percent_Identity=34.1121495327103, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI154350220, Length=302, Percent_Identity=28.8079470198675, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=47.2222222222222, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI5729982, Length=123, Percent_Identity=37.3983739837398, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786425, Length=345, Percent_Identity=58.5507246376812, Blast_Score=400, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI193205700, Length=407, Percent_Identity=29.7297297297297, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17537959, Length=307, Percent_Identity=27.0358306188925, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI193205702, Length=348, Percent_Identity=25, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534089, Length=125, Percent_Identity=38.4, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=204, Percent_Identity=28.921568627451, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19923006, Length=325, Percent_Identity=29.8461538461538, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=29.3286219081272, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=29.3286219081272, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24668444, Length=129, Percent_Identity=38.7596899224806, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40892; Mature: 40892

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSA
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHCCCHHHCCHHHHHHHHHHC
MPTAQALKLCPQLHVVPGRMSVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQ
CCHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCC
GSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLNKPDGLYVVTPDKVQEMVDSL
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHC
PLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVT
CHHHCCCCHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADF
HHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHCCCEEEECCH
QQTTIEHVHPALELDYFHELLEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSA
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHCCCHHHCCHHHHHHHHHHC
MPTAQALKLCPQLHVVPGRMSVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQ
CCHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCC
GSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLNKPDGLYVVTPDKVQEMVDSL
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHC
PLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVT
CHHHCCCCHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADF
HHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHCCCEEEECCH
QQTTIEHVHPALELDYFHELLEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA