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The map label for this gene is pgpA [H]

Identifier: 227082389

GI number: 227082389

Start: 2357750

End: 2358259

Strand: Reverse

Name: pgpA [H]

Synonym: VCM66_2188

Alternate gene names: 227082389

Gene position: 2358259-2357750 (Counterclockwise)

Preceding gene: 227082390

Following gene: 227082387

Centisome position: 81.53

GC content: 48.82

Gene sequence:

>510_bases
ATGAGCGATCCACGCAGTAATCTCTCCTTAAGTAACCCTTGGCACTTGCTTGCTACTGGTTTTGGCAGTGGCTTGTCGCC
CATCGTGCCCGGAACGATGGGCACGTTAGCATCGGTGCCATTTTATCTAATGCTGGCACAGCTCCCTTGGATTCTGTATG
CCGTCGTGGTTGTGTTCGCTAGCCTCATCGGCATAAAAATTTGCCAAGTCACCTCAGATGATATGCAGGTACACGATCAC
GGTTCGATTGTTTGGGATGAATTTGCCGGCTTTTGGATCACTATGCTGATTGTGCCGTTATACCAATTACCGGTTTTCGA
TTGGAAATGGCTCGTGACAGGTTTTGTGCTATTTCGCTTTTTCGATATGCTCAAACCTTGGCCGATCAGTTGGTTGGATA
AGCGTGTGCATGGCGGTTTCGGCATCATGATTGATGATTTAGTGGCTGGAGTAATGGCCGCGATAAGTTTAGCGGCCATC
GGCTACTGGTTAGAGTGGCTGCCTGTTTGA

Upstream 100 bases:

>100_bases
GTATTGGCCAAATTCGCCCGGCCGGTACGTTTGAGCTGCACAATCAGGGGAAAAAGCTCGATTGGCAACTGGCTGGGTAT
GATCATTTCAAGGTGAAAGC

Downstream 100 bases:

>100_bases
GATTCGCCTGTTTAGGTTCCCCTAGGGGAACCTAACTCAGCTAGTTTAATTTTTGCAAATCGGCTTCAATTTCGGCAATT
TTACTGGCAACGACCTTTTC

Product: phosphatidylglycerophosphatase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSDPRSNLSLSNPWHLLATGFGSGLSPIVPGTMGTLASVPFYLMLAQLPWILYAVVVVFASLIGIKICQVTSDDMQVHDH
GSIVWDEFAGFWITMLIVPLYQLPVFDWKWLVTGFVLFRFFDMLKPWPISWLDKRVHGGFGIMIDDLVAGVMAAISLAAI
GYWLEWLPV

Sequences:

>Translated_169_residues
MSDPRSNLSLSNPWHLLATGFGSGLSPIVPGTMGTLASVPFYLMLAQLPWILYAVVVVFASLIGIKICQVTSDDMQVHDH
GSIVWDEFAGFWITMLIVPLYQLPVFDWKWLVTGFVLFRFFDMLKPWPISWLDKRVHGGFGIMIDDLVAGVMAAISLAAI
GYWLEWLPV
>Mature_168_residues
SDPRSNLSLSNPWHLLATGFGSGLSPIVPGTMGTLASVPFYLMLAQLPWILYAVVVVFASLIGIKICQVTSDDMQVHDHG
SIVWDEFAGFWITMLIVPLYQLPVFDWKWLVTGFVLFRFFDMLKPWPISWLDKRVHGGFGIMIDDLVAGVMAAISLAAIG
YWLEWLPV

Specific function: One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate [H]

COG id: COG1267

COG function: function code I; Phosphatidylglycerophosphatase A and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786620, Length=158, Percent_Identity=60.126582278481, Blast_Score=197, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007686 [H]

Pfam domain/function: PF04608 PgpA [H]

EC number: =3.1.3.27 [H]

Molecular weight: Translated: 18931; Mature: 18799

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPRSNLSLSNPWHLLATGFGSGLSPIVPGTMGTLASVPFYLMLAQLPWILYAVVVVFA
CCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIGIKICQVTSDDMQVHDHGSIVWDEFAGFWITMLIVPLYQLPVFDWKWLVTGFVLFRF
HHHHHHHHEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FDMLKPWPISWLDKRVHGGFGIMIDDLVAGVMAAISLAAIGYWLEWLPV
HHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDPRSNLSLSNPWHLLATGFGSGLSPIVPGTMGTLASVPFYLMLAQLPWILYAVVVVFA
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIGIKICQVTSDDMQVHDHGSIVWDEFAGFWITMLIVPLYQLPVFDWKWLVTGFVLFRF
HHHHHHHHEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FDMLKPWPISWLDKRVHGGFGIMIDDLVAGVMAAISLAAIGYWLEWLPV
HHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2846510; 9278503 [H]