Click here to switch to the map view.

The map label for this gene is cidA [H]

Identifier: 227082227

GI number: 227082227

Start: 2197991

End: 2198431

Strand: Reverse

Name: cidA [H]

Synonym: VCM66_2025

Alternate gene names: 227082227

Gene position: 2198431-2197991 (Counterclockwise)

Preceding gene: 227082228

Following gene: 227082226

Centisome position: 76.0

GC content: 48.3

Gene sequence:

>441_bases
ATGCAAAACGTTACGCGTACTTTTCAGTTCAAGCATAGCCTACTGATTGTCGTTCAAGTGGCGGCACTTTCACTGATTTG
GTTTTTCTCCGATTGGTTGGTCAATCAGTTTCAACTGCCGTTACCCGCCAATTTAACGGGAATGCTGATTTTGTTGTTAC
TGGTTATGCTCAAAGTAGTGAATGTTGAGTGGTTTCGGCGCGGGGCGAGCTGGTTGCTGGCTGAAATGTTGCTGTTTTTT
GTTCCGGCTGTCGTGGCGGTAGTGAATTACCAAGACTTAATGCGCCAAGAGGGGATTAAAATTGCTGTGGTTTTAGTGGC
CAGCACCATCTTGGTGATCGCATCGACGGCTTGGGTCGTCGATAAAATGCATCGAGTTGAGCTGGTTTTAGCGAGACGTA
AACGTCGCCAGATAGCGCTGGCGCGCAGTGTGGAGAAGTAG

Upstream 100 bases:

>100_bases
ATGCCTAAATGGCATGAATTAAATAAATTTAAGTCATTTTATGCTGGTAATCGCCCGGAATACAATGTGACCCAGTTCCC
ATTTTATCTAGGCAACCTTA

Downstream 100 bases:

>100_bases
AACATATGTCGACTTCATTACTCAGCCTTTTCTGTTTTCTGCTCACGTTACTGTTTTACTATGCGAGTAAATTTCTTTAT
CGACGTAAACGCAGTTTGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MQNVTRTFQFKHSLLIVVQVAALSLIWFFSDWLVNQFQLPLPANLTGMLILLLLVMLKVVNVEWFRRGASWLLAEMLLFF
VPAVVAVVNYQDLMRQEGIKIAVVLVASTILVIASTAWVVDKMHRVELVLARRKRRQIALARSVEK

Sequences:

>Translated_146_residues
MQNVTRTFQFKHSLLIVVQVAALSLIWFFSDWLVNQFQLPLPANLTGMLILLLLVMLKVVNVEWFRRGASWLLAEMLLFF
VPAVVAVVNYQDLMRQEGIKIAVVLVASTILVIASTAWVVDKMHRVELVLARRKRRQIALARSVEK
>Mature_146_residues
MQNVTRTFQFKHSLLIVVQVAALSLIWFFSDWLVNQFQLPLPANLTGMLILLLLVMLKVVNVEWFRRGASWLLAEMLLFF
VPAVVAVVNYQDLMRQEGIKIAVVLVASTILVIASTAWVVDKMHRVELVLARRKRRQIALARSVEK

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 16743; Mature: 16743

Theoretical pI: Translated: 11.53; Mature: 11.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNVTRTFQFKHSLLIVVQVAALSLIWFFSDWLVNQFQLPLPANLTGMLILLLLVMLKVV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
NVEWFRRGASWLLAEMLLFFVPAVVAVVNYQDLMRQEGIKIAVVLVASTILVIASTAWVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DKMHRVELVLARRKRRQIALARSVEK
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNVTRTFQFKHSLLIVVQVAALSLIWFFSDWLVNQFQLPLPANLTGMLILLLLVMLKVV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
NVEWFRRGASWLLAEMLLFFVPAVVAVVNYQDLMRQEGIKIAVVLVASTILVIASTAWVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DKMHRVELVLARRKRRQIALARSVEK
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA