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The map label for this gene is pabC [H]

Identifier: 227082145

GI number: 227082145

Start: 2108913

End: 2109746

Strand: Reverse

Name: pabC [H]

Synonym: VCM66_1942

Alternate gene names: 227082145

Gene position: 2109746-2108913 (Counterclockwise)

Preceding gene: 227082146

Following gene: 227082144

Centisome position: 72.94

GC content: 47.6

Gene sequence:

>834_bases
TTGAGCCGTTTCTTTTTATGGAGTGAGAGCATGTACTGGGTCAATGGTCAACGGCGTAATGAAGTGCCTATTCATGATCG
ATCATTTCAGTATGGCGATGGTTGCTTCACGACTATACTGACCAAAGAAGGTCAGGTGCAGCAATGGTCCTCACATAAGG
CGCGATTACAGGCCTGTCTTGATATCTTGCACATACCCGAGCCCAATTGGGATCGGGTATGGCAGGGACTGCAAAGCATG
ATCCTGCCGCAGGAGAAAGCTGGACTGAAAATACACATCAGCCGAGGTTTGGGAGGGCGAGGTTACAGTCCTACTCAAGT
GAGTGAAAGCATTGTTACTATTAGCGCCTTTGCTTTTCCTGCCCACTATCAAGCATGGCGTGATAAGGGATTGGCTGTGG
GGATTTGTCAGCAGCGAATGGGATTAAATCCTCTGTTGGCGGGGCACAAACATAATAATCGACTGGAGCAGATCCTACTC
AAACGCGAGATGGATAACGCGGGATGGGATGATGGGGTCTGTTTAGACATCAATGGCAAGGTGATTGAAACCACCGCAGC
TAATATATTTTGGTGTAGAGATGGGACGATGTTTACACCTTGTTTAAGACATGCCGGAGTCGCCGGTGTTGCGCGTCGAC
AGATACTCGAACTCGCGCAGCAACAAGAGATTCCTATTGTGATTGATGAATTTACGCTGGAAGACCTATTGAGTGCTGAG
GAAGTGTTTATTACCAATGCCTTACTTGAGGTTGCTCCAGTCACACAAATTGGTCAACAACGATTGACGATAGGTAGCAT
GACGCGACGATTTCAGGAGAGTAGTAATTCGTGA

Upstream 100 bases:

>100_bases
ACTCGTTTGGCTTTGGTGGTACTAACGGTAGCTTGATTTTCAAGCGCATGTAAAAACTTCATCACTCTTTACTTGAGTTA
AGACGGCTTGATGCATAGCA

Downstream 100 bases:

>100_bases
TTAAAAAGCGGGTATTGGTGTTGGTTGCTCTGATCGGTATTGTGGCAGGCAGCTACTTTTATGTTGTTAAGCAGATGGAT
CAGTATCTGGCTCAGCCTTT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSRFFLWSESMYWVNGQRRNEVPIHDRSFQYGDGCFTTILTKEGQVQQWSSHKARLQACLDILHIPEPNWDRVWQGLQSM
ILPQEKAGLKIHISRGLGGRGYSPTQVSESIVTISAFAFPAHYQAWRDKGLAVGICQQRMGLNPLLAGHKHNNRLEQILL
KREMDNAGWDDGVCLDINGKVIETTAANIFWCRDGTMFTPCLRHAGVAGVARRQILELAQQQEIPIVIDEFTLEDLLSAE
EVFITNALLEVAPVTQIGQQRLTIGSMTRRFQESSNS

Sequences:

>Translated_277_residues
MSRFFLWSESMYWVNGQRRNEVPIHDRSFQYGDGCFTTILTKEGQVQQWSSHKARLQACLDILHIPEPNWDRVWQGLQSM
ILPQEKAGLKIHISRGLGGRGYSPTQVSESIVTISAFAFPAHYQAWRDKGLAVGICQQRMGLNPLLAGHKHNNRLEQILL
KREMDNAGWDDGVCLDINGKVIETTAANIFWCRDGTMFTPCLRHAGVAGVARRQILELAQQQEIPIVIDEFTLEDLLSAE
EVFITNALLEVAPVTQIGQQRLTIGSMTRRFQESSNS
>Mature_276_residues
SRFFLWSESMYWVNGQRRNEVPIHDRSFQYGDGCFTTILTKEGQVQQWSSHKARLQACLDILHIPEPNWDRVWQGLQSMI
LPQEKAGLKIHISRGLGGRGYSPTQVSESIVTISAFAFPAHYQAWRDKGLAVGICQQRMGLNPLLAGHKHNNRLEQILLK
REMDNAGWDDGVCLDINGKVIETTAANIFWCRDGTMFTPCLRHAGVAGVARRQILELAQQQEIPIVIDEFTLEDLLSAEE
VFITNALLEVAPVTQIGQQRLTIGSMTRRFQESSNS

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=248, Percent_Identity=38.3064516129032, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI48994963, Length=281, Percent_Identity=25.9786476868327, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 31335; Mature: 31204

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFFLWSESMYWVNGQRRNEVPIHDRSFQYGDGCFTTILTKEGQVQQWSSHKARLQACL
CCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
DILHIPEPNWDRVWQGLQSMILPQEKAGLKIHISRGLGGRGYSPTQVSESIVTISAFAFP
HHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHEEEEEEHHCC
AHYQAWRDKGLAVGICQQRMGLNPLLAGHKHNNRLEQILLKREMDNAGWDDGVCLDINGK
HHHHHHHHCCCEEEEHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCE
VIETTAANIFWCRDGTMFTPCLRHAGVAGVARRQILELAQQQEIPIVIDEFTLEDLLSAE
EEEEECCEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
EVFITNALLEVAPVTQIGQQRLTIGSMTRRFQESSNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRFFLWSESMYWVNGQRRNEVPIHDRSFQYGDGCFTTILTKEGQVQQWSSHKARLQACL
CCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
DILHIPEPNWDRVWQGLQSMILPQEKAGLKIHISRGLGGRGYSPTQVSESIVTISAFAFP
HHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHEEEEEEHHCC
AHYQAWRDKGLAVGICQQRMGLNPLLAGHKHNNRLEQILLKREMDNAGWDDGVCLDINGK
HHHHHHHHCCCEEEEHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCE
VIETTAANIFWCRDGTMFTPCLRHAGVAGVARRQILELAQQQEIPIVIDEFTLEDLLSAE
EEEEECCEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
EVFITNALLEVAPVTQIGQQRLTIGSMTRRFQESSNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]