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The map label for this gene is bioH [C]

Identifier: 227082113

GI number: 227082113

Start: 2075945

End: 2076799

Strand: Reverse

Name: bioH [C]

Synonym: VCM66_1910

Alternate gene names: 227082113

Gene position: 2076799-2075945 (Counterclockwise)

Preceding gene: 227082114

Following gene: 227082112

Centisome position: 71.8

GC content: 51.46

Gene sequence:

>855_bases
ATGAACTCTATTTCAACCACTTATCTGCTCGAACAAGGCCAATTAGCGGCCATTGAAGTGGGCAATGCAAAAATGGCCGA
AGTCTCGGTCATTTTTATTCACGGCTGGCTGGATAACGCGGCGAGTTTCTTGTCACTGATGCCTGCGTTACATGCGTTGG
ATCCTAAGCTGCATCTGTGCGCGGTTGATCTGCCCGGTCACGGTTTCTCTAGCCACAAAGCGGGTTACTCTGCATTTCAC
GACTATATCGATGATCTCGATCAGCTGTTGCTCAACTTATCGCCAAACAAACCAGTGCTAGTGGGGCATTCGCTTGGTGC
TTTAATCGCAAGTTGTTATAGTGCCGCCTTTCCCGAGCAAGTCAGCGGTTTAGTGCAGATAGAAGGCTTCGGACCACTCT
CTGAACCTGCCACGCACAGTGTCACGCGTTTGCGGCAAGGGATACGCTCGCGCCATGCGTTACGCAACGCAAAACCTCGT
GGGTATGCCAGCTTTGAACATGCACTGCGTCACCGTGCTTTGGTCAATCAGTTACCGGCTGAATTGCTGCGTCCGTTGGT
CGAACGTGGTACTTATCAGCATGACGAGCAGTGGTTCTGGCGGCATGATCTTAAGCTCAAGGCGGACTCTTTATATCGCA
TGACGCCGGAACACGCCGCGCAGGTGCGCGAATCAATCCATTGTCCGCAGCAGGTGATTTTGGGCTCGCAGGGGTTTGCC
ACACTCAAGCAACAAGCACAAAACCCAGAGTTTGCGACCATCCATATAGCAACGGTGACGGGCGGGCATCACTGCCATTT
AGAGCAACCTCAAGCGGTCGCTGAATTGATTTTTGGCTTAGTTAACAAAATTTAA

Upstream 100 bases:

>100_bases
AAGTCGATGATATTGGCCCTTACATGTTCCCTTGTCGCGGTTTCTACTGTTGGCCAAGGACGATGCCTGAGCGGGACGGT
AAGATCATTCAAGAAGTTAA

Downstream 100 bases:

>100_bases
ACAAGTGTTTGAGAGTTACGTGCTCAAGCACCTCGGCTGTGCTGTAATAGCGGTCAGCATTTGCATGACTACTGCATGAT
GACAACAACAAGAATAGCGC

Product: putative serine hydrolase

Products: NA

Alternate protein names: Hydrolase; Alpha/Beta Fold Family Hydrolase; Alpha/Beta Hydrolase Fold Protein; Hydrolase Alpha/Beta Fold Family; Alpha/Beta Hydrolase; Hydrolase Protein; Hydrolase/Acyltransferase; Lipase A; Lipase; Alpha/Beta Fold Superfamily Hydrolase; Esterase; Hydrolase Or Acytransferase; Alpha/Beta Hydrolase Fold Family; Alpha/Beta Hydrolase Family Protein; Lipase LipA; Hydrolase Alpha/Beta Fold Family Protein; Epoxide Hydrolase; Alpha/Beta Superfamily Hydrolase; Alpha/Beta Fold Hydrolase Family Protein; Polyketide Synthase

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MNSISTTYLLEQGQLAAIEVGNAKMAEVSVIFIHGWLDNAASFLSLMPALHALDPKLHLCAVDLPGHGFSSHKAGYSAFH
DYIDDLDQLLLNLSPNKPVLVGHSLGALIASCYSAAFPEQVSGLVQIEGFGPLSEPATHSVTRLRQGIRSRHALRNAKPR
GYASFEHALRHRALVNQLPAELLRPLVERGTYQHDEQWFWRHDLKLKADSLYRMTPEHAAQVRESIHCPQQVILGSQGFA
TLKQQAQNPEFATIHIATVTGGHHCHLEQPQAVAELIFGLVNKI

Sequences:

>Translated_284_residues
MNSISTTYLLEQGQLAAIEVGNAKMAEVSVIFIHGWLDNAASFLSLMPALHALDPKLHLCAVDLPGHGFSSHKAGYSAFH
DYIDDLDQLLLNLSPNKPVLVGHSLGALIASCYSAAFPEQVSGLVQIEGFGPLSEPATHSVTRLRQGIRSRHALRNAKPR
GYASFEHALRHRALVNQLPAELLRPLVERGTYQHDEQWFWRHDLKLKADSLYRMTPEHAAQVRESIHCPQQVILGSQGFA
TLKQQAQNPEFATIHIATVTGGHHCHLEQPQAVAELIFGLVNKI
>Mature_284_residues
MNSISTTYLLEQGQLAAIEVGNAKMAEVSVIFIHGWLDNAASFLSLMPALHALDPKLHLCAVDLPGHGFSSHKAGYSAFH
DYIDDLDQLLLNLSPNKPVLVGHSLGALIASCYSAAFPEQVSGLVQIEGFGPLSEPATHSVTRLRQGIRSRHALRNAKPR
GYASFEHALRHRALVNQLPAELLRPLVERGTYQHDEQWFWRHDLKLKADSLYRMTPEHAAQVRESIHCPQQVILGSQGFA
TLKQQAQNPEFATIHIATVTGGHHCHLEQPQAVAELIFGLVNKI

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI18777795, Length=271, Percent_Identity=25.4612546125461, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24667992, Length=276, Percent_Identity=25.7246376811594, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21357291, Length=276, Percent_Identity=25.7246376811594, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17137390, Length=266, Percent_Identity=29.3233082706767, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667999, Length=274, Percent_Identity=24.8175182481752, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24655874, Length=296, Percent_Identity=25.6756756756757, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356953, Length=290, Percent_Identity=24.8275862068966, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356937, Length=271, Percent_Identity=25.830258302583, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655886, Length=291, Percent_Identity=24.3986254295533, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 31340; Mature: 31340

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSISTTYLLEQGQLAAIEVGNAKMAEVSVIFIHGWLDNAASFLSLMPALHALDPKLHLC
CCCCCHHEEECCCCEEEEEECCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEE
AVDLPGHGFSSHKAGYSAFHDYIDDLDQLLLNLSPNKPVLVGHSLGALIASCYSAAFPEQ
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCHHH
VSGLVQIEGFGPLSEPATHSVTRLRQGIRSRHALRNAKPRGYASFEHALRHRALVNQLPA
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ELLRPLVERGTYQHDEQWFWRHDLKLKADSLYRMTPEHAAQVRESIHCPQQVILGSQGFA
HHHHHHHHCCCCCCCCHHHHHHCCEECCCHHHHCCHHHHHHHHHHHCCCHHHHCCCCCHH
TLKQQAQNPEFATIHIATVTGGHHCHLEQPQAVAELIFGLVNKI
HHHHHCCCCCEEEEEEEEECCCCEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSISTTYLLEQGQLAAIEVGNAKMAEVSVIFIHGWLDNAASFLSLMPALHALDPKLHLC
CCCCCHHEEECCCCEEEEEECCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEE
AVDLPGHGFSSHKAGYSAFHDYIDDLDQLLLNLSPNKPVLVGHSLGALIASCYSAAFPEQ
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCHHH
VSGLVQIEGFGPLSEPATHSVTRLRQGIRSRHALRNAKPRGYASFEHALRHRALVNQLPA
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ELLRPLVERGTYQHDEQWFWRHDLKLKADSLYRMTPEHAAQVRESIHCPQQVILGSQGFA
HHHHHHHHCCCCCCCCHHHHHHCCEECCCHHHHCCHHHHHHHHHHHCCCHHHHCCCCCHH
TLKQQAQNPEFATIHIATVTGGHHCHLEQPQAVAELIFGLVNKI
HHHHHCCCCCEEEEEEEEECCCCEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA