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The map label for this gene is tolR [H]

Identifier: 227081967

GI number: 227081967

Start: 1915965

End: 1916405

Strand: Reverse

Name: tolR [H]

Synonym: VCM66_1761

Alternate gene names: 227081967

Gene position: 1916405-1915965 (Counterclockwise)

Preceding gene: 227081968

Following gene: 227081966

Centisome position: 66.25

GC content: 43.08

Gene sequence:

>441_bases
ATGGCTGGCTATCAAACCAAAAAACGTGAGATGAAAGCAGAGATTAACGTGGTTCCTTACATCGACGTTATGCTGGTTCT
CCTCATTATTTTTATGGTGACATCACCGTTTGTAACACAAGGTGTGGATGTGGAGTTGCCGAAAACTCATTCGGCTAAAT
CAGCACAAGATCTAGCGGGTGATAGCGATTCTAGCTTTATCATTGTTGAGATTGATAAAGAAGGTAATCTTGGCCTGAGT
GTTAATGATGAAGAAGTTCAACGCGGTCTATCCATCGAAGATGTGATTGTTCGAGTGAAAGCAGAATTGTCTCTTAAACC
TAATTCACCTGTGGCCGTGGGTGGCGATGCCGCTACACCTTACGCAGAGATTGTTTTGGTATTGGATGAGTTGGGTCAAG
CTGGTATTCCTAAAGTAGGGCTACTCACGGACCTTAAATAA

Upstream 100 bases:

>100_bases
TTAGCAATAAAGTCAGTAAGCTTGAACATACTTACGCTACCTTCTCGGAAGAGTTTCATACCATTCTCCACCGTCAAGTG
ATGGCTGGCAGGGAATAACT

Downstream 100 bases:

>100_bases
TAGGTTTAATACTGAGCATGAAAGAGAATAAGTCCAGAAAAAGTAATGATGCTAAATCGATAACTATTTCGCTGGCGATG
CACGGTGCTTTGGTCGCGAT

Product: tolR membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MAGYQTKKREMKAEINVVPYIDVMLVLLIIFMVTSPFVTQGVDVELPKTHSAKSAQDLAGDSDSSFIIVEIDKEGNLGLS
VNDEEVQRGLSIEDVIVRVKAELSLKPNSPVAVGGDAATPYAEIVLVLDELGQAGIPKVGLLTDLK

Sequences:

>Translated_146_residues
MAGYQTKKREMKAEINVVPYIDVMLVLLIIFMVTSPFVTQGVDVELPKTHSAKSAQDLAGDSDSSFIIVEIDKEGNLGLS
VNDEEVQRGLSIEDVIVRVKAELSLKPNSPVAVGGDAATPYAEIVLVLDELGQAGIPKVGLLTDLK
>Mature_145_residues
AGYQTKKREMKAEINVVPYIDVMLVLLIIFMVTSPFVTQGVDVELPKTHSAKSAQDLAGDSDSSFIIVEIDKEGNLGLSV
NDEEVQRGLSIEDVIVRVKAELSLKPNSPVAVGGDAATPYAEIVLVLDELGQAGIPKVGLLTDLK

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1786959, Length=134, Percent_Identity=36.5671641791045, Blast_Score=66, Evalue=8e-13,
Organism=Escherichia coli, GI1789380, Length=129, Percent_Identity=34.1085271317829, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 15650; Mature: 15519

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGYQTKKREMKAEINVVPYIDVMLVLLIIFMVTSPFVTQGVDVELPKTHSAKSAQDLAG
CCCCCCHHHHHHHHCCEECHHHHHHHHHHHHHHCCCCHHCCCCEECCCCCCCCCHHHHCC
DSDSSFIIVEIDKEGNLGLSVNDEEVQRGLSIEDVIVRVKAELSLKPNSPVAVGGDAATP
CCCCCEEEEEECCCCCCCCEECHHHHHCCCCHHHHEEEEEEEEEECCCCCEEECCCCCCC
YAEIVLVLDELGQAGIPKVGLLTDLK
HHHHHHHHHHCCCCCCCCCCCEECCC
>Mature Secondary Structure 
AGYQTKKREMKAEINVVPYIDVMLVLLIIFMVTSPFVTQGVDVELPKTHSAKSAQDLAG
CCCCCHHHHHHHHCCEECHHHHHHHHHHHHHHCCCCHHCCCCEECCCCCCCCCHHHHCC
DSDSSFIIVEIDKEGNLGLSVNDEEVQRGLSIEDVIVRVKAELSLKPNSPVAVGGDAATP
CCCCCEEEEEECCCCCCCCEECHHHHHCCCCHHHHEEEEEEEEEECCCCCEEECCCCCCC
YAEIVLVLDELGQAGIPKVGLLTDLK
HHHHHHHHHHCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]