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The map label for this gene is aroH [H]

Identifier: 227081665

GI number: 227081665

Start: 1567979

End: 1569166

Strand: Direct

Name: aroH [H]

Synonym: VCM66_1449

Alternate gene names: 227081665

Gene position: 1567979-1569166 (Clockwise)

Preceding gene: 227081663

Following gene: 227081666

Centisome position: 54.21

GC content: 48.06

Gene sequence:

>1188_bases
TTGGTCAAATGCTCGGTTTTTACTTCAATTTACACCCCTTTCCGCAGCTGTTTTCGGCGTAATGGTTTATTCTCGTTGAC
AAATTCGTTATCTTTAGCGCTTCGCAATAAAAGGACAGGCGCTCCTATGCCACTGAAAACCGATGAATTAAGAACCCAAG
CATTGGGACCTATGCCTACTCCGGCAGAATTAAGTCACGCACATCCTATCACTGATGAAGTTGCGCTACGGATCGCGCAG
TCTCGTCGCCAAATTGAAAGCATTCTTACCGGTGAAGATGATCGCCTATTAGTGATAGTGGGGCCTTGTTCGGTGCATGA
TACCGATGCCGCACTCGACTACGCTCGCCGCCTTGCTGCGCTACAAGAAAACTATACTGATGAGCTTTTTGTGGTGATGC
GGACCTATTTCGAAAAACCACGTACTGTGGTGGGTTGGAAAGGACTGATCACCGATCCAAACTTAGATGGCTCTTACGCT
TTAGAAACCGGTCTCAATAAAGCGCGAAAGTTGCTGCTTGATGTAAACAAGCTCGGATTGGCTACCGCGACCGAGTTTCT
TGATATGATCACAGGCCAATACATCGCGGACCTTATCACGTGGGGCGCAATTGGTGCGCGTACCACTGAGTCGCAAATTC
ACCGTGAGATGGCCTCTGCGCTCTCCTGCCCTGTGGGTTTTAAAAATGGCACTAACGGTAATGTGAAAATCGCGATTGAT
GCGATCCGCGCGGCCAAAGCGTCACATTACTTCTATTCACCAGATAAGAATGGTCGTATGACGGTTTACCGTACCAGTGG
TAACCCATTTGGTCATATTATTCTGCGTGGTGGTGATAGCGGACCAAACTTTGATGCGGCTTCGATTAATGAAGCTTGCC
AGCAGTTGGCGCAATTCAACTTACCAGAGCGTTTAGTGGTGGATTTCAGCCACGCGAACTGTCAAAAACAACACCGTAAA
CAAGTGGATGTCGCGCGCGATATTTGCCAGCAAATTGAAGCTGGCAGCCACAAAATTGCGGGCATCATGGCGGAAAGCTT
CCTTGTGGAAGGCAATCAGCCAATGCACGATCTCAATAATCTGACTTATGGTCTGTCGATCACCGATCCTTGTTTAGGAT
GGAAAGATACCGCCACCATGCTTGATATGCTGGCTCAATCGATCAAAGTCCGTCGTTCTCGTCATTAA

Upstream 100 bases:

>100_bases
TAAATGTCAAACAAATGTTAACAAAATGCTGAGCCACGACGCTTTCTGAGCAAAGTGAAGAGATAAGTCTGCTTGGTTGT
GATGGGGTTACGCAGGCGGT

Downstream 100 bases:

>100_bases
GGAAATACCTCATGCCTTCTTTTGATATTGTTTCAGAAATTGATGCGGTTGAGCTGCGTAACGCAGTCGAAAACTCAACG
CGTGAACTCGCTAGCCGATT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MVKCSVFTSIYTPFRSCFRRNGLFSLTNSLSLALRNKRTGAPMPLKTDELRTQALGPMPTPAELSHAHPITDEVALRIAQ
SRRQIESILTGEDDRLLVIVGPCSVHDTDAALDYARRLAALQENYTDELFVVMRTYFEKPRTVVGWKGLITDPNLDGSYA
LETGLNKARKLLLDVNKLGLATATEFLDMITGQYIADLITWGAIGARTTESQIHREMASALSCPVGFKNGTNGNVKIAID
AIRAAKASHYFYSPDKNGRMTVYRTSGNPFGHIILRGGDSGPNFDAASINEACQQLAQFNLPERLVVDFSHANCQKQHRK
QVDVARDICQQIEAGSHKIAGIMAESFLVEGNQPMHDLNNLTYGLSITDPCLGWKDTATMLDMLAQSIKVRRSRH

Sequences:

>Translated_395_residues
MVKCSVFTSIYTPFRSCFRRNGLFSLTNSLSLALRNKRTGAPMPLKTDELRTQALGPMPTPAELSHAHPITDEVALRIAQ
SRRQIESILTGEDDRLLVIVGPCSVHDTDAALDYARRLAALQENYTDELFVVMRTYFEKPRTVVGWKGLITDPNLDGSYA
LETGLNKARKLLLDVNKLGLATATEFLDMITGQYIADLITWGAIGARTTESQIHREMASALSCPVGFKNGTNGNVKIAID
AIRAAKASHYFYSPDKNGRMTVYRTSGNPFGHIILRGGDSGPNFDAASINEACQQLAQFNLPERLVVDFSHANCQKQHRK
QVDVARDICQQIEAGSHKIAGIMAESFLVEGNQPMHDLNNLTYGLSITDPCLGWKDTATMLDMLAQSIKVRRSRH
>Mature_395_residues
MVKCSVFTSIYTPFRSCFRRNGLFSLTNSLSLALRNKRTGAPMPLKTDELRTQALGPMPTPAELSHAHPITDEVALRIAQ
SRRQIESILTGEDDRLLVIVGPCSVHDTDAALDYARRLAALQENYTDELFVVMRTYFEKPRTVVGWKGLITDPNLDGSYA
LETGLNKARKLLLDVNKLGLATATEFLDMITGQYIADLITWGAIGARTTESQIHREMASALSCPVGFKNGTNGNVKIAID
AIRAAKASHYFYSPDKNGRMTVYRTSGNPFGHIILRGGDSGPNFDAASINEACQQLAQFNLPERLVVDFSHANCQKQHRK
QVDVARDICQQIEAGSHKIAGIMAESFLVEGNQPMHDLNNLTYGLSITDPCLGWKDTATMLDMLAQSIKVRRSRH

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=346, Percent_Identity=66.4739884393064, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI1786969, Length=350, Percent_Identity=55.1428571428571, Blast_Score=396, Evalue=1e-111,
Organism=Escherichia coli, GI1788953, Length=330, Percent_Identity=48.7878787878788, Blast_Score=330, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6319726, Length=347, Percent_Identity=45.821325648415, Blast_Score=320, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6320240, Length=354, Percent_Identity=42.3728813559322, Blast_Score=304, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 43671; Mature: 43671

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKCSVFTSIYTPFRSCFRRNGLFSLTNSLSLALRNKRTGAPMPLKTDELRTQALGPMPT
CEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCC
PAELSHAHPITDEVALRIAQSRRQIESILTGEDDRLLVIVGPCSVHDTDAALDYARRLAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
LQENYTDELFVVMRTYFEKPRTVVGWKGLITDPNLDGSYALETGLNKARKLLLDVNKLGL
HHHCCCHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ATATEFLDMITGQYIADLITWGAIGARTTESQIHREMASALSCPVGFKNGTNGNVKIAID
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
AIRAAKASHYFYSPDKNGRMTVYRTSGNPFGHIILRGGDSGPNFDAASINEACQQLAQFN
EHHHHHHCCCEECCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCC
LPERLVVDFSHANCQKQHRKQVDVARDICQQIEAGSHKIAGIMAESFLVEGNQPMHDLNN
CCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHC
LTYGLSITDPCLGWKDTATMLDMLAQSIKVRRSRH
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKCSVFTSIYTPFRSCFRRNGLFSLTNSLSLALRNKRTGAPMPLKTDELRTQALGPMPT
CEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCC
PAELSHAHPITDEVALRIAQSRRQIESILTGEDDRLLVIVGPCSVHDTDAALDYARRLAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
LQENYTDELFVVMRTYFEKPRTVVGWKGLITDPNLDGSYALETGLNKARKLLLDVNKLGL
HHHCCCHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ATATEFLDMITGQYIADLITWGAIGARTTESQIHREMASALSCPVGFKNGTNGNVKIAID
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
AIRAAKASHYFYSPDKNGRMTVYRTSGNPFGHIILRGGDSGPNFDAASINEACQQLAQFN
EHHHHHHCCCEECCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCC
LPERLVVDFSHANCQKQHRKQVDVARDICQQIEAGSHKIAGIMAESFLVEGNQPMHDLNN
CCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHC
LTYGLSITDPCLGWKDTATMLDMLAQSIKVRRSRH
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]