| Definition | Vibrio cholerae M66-2 chromosome I, complete genome. |
|---|---|
| Accession | NC_012578 |
| Length | 2,892,523 |
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The map label for this gene is prc [H]
Identifier: 227081655
GI number: 227081655
Start: 1554313
End: 1556310
Strand: Reverse
Name: prc [H]
Synonym: VCM66_1439
Alternate gene names: 227081655
Gene position: 1556310-1554313 (Counterclockwise)
Preceding gene: 227081656
Following gene: 227081654
Centisome position: 53.8
GC content: 44.24
Gene sequence:
>1998_bases ATGAAATGCCGTTCAAAAATATCTCTGATTGCTGCTAGCCTATGGCTGGCAGCCTTTTCAGCTCAGGCTCTAGAAGCCAA ACTCAAACCAGAAGATCTCCCTCTTCTTGTTCCTGAAGCTCAACACGCAACGGCAGCGAAACGTGTTACCTCACGTTTTA CCCGTTCTCATTACAAACAATTCAATTTAGACGACCAGTTTTCTCAAGCCATGTTTGAACGCTACCTTGAGATGCTGGAT TACAGTCGAAATATCTTTACTCAAGCGGACATAGACAGCTTCAAAGCTTGGTCTTTGCAATTGGATGACCAATTAAAAGC AGGTGACAATCAAATCGCTTACGATCTGTATAACCTGTCAATGGAAAAACGTTTTGAGCGCTTTCAATACGCACTTTCTC TGCTTGATCAAGAGATGACGTTTGATGCTGATGAGTCTATTGAGCTTGATCGTACGAAATCGCCTTGGCCAAAAGATCTT AAAGAGATTAACGAGCTGTGGAGACAACGAGTTAAATACGATGCGTTAAGCTTGAAACTGGCAGGTAAAGAGTGGCCAGA AATCAAAGAAACGCTCGATAAACGGTACAACAATGCCATCAAGCGCCTCACACAGACAAAAAGTGAAGACGTATTTCAAA CTTATATGAATGCGTTTGCGCGTGAAGTTGATCCGCACACCAGCTATTTGTCACCGCGTAACGCAGAACAATTCCAATCT GAAATGAATCTCTCGTTGGAAGGGATTGGTGCCGTGTTACAAATGACCGACGATTACACCATCATCCGCTCATTGGTTGC AGGTGGTCCTGCAGCATTGAGCAAACAATTGGGTGAGGGTGACCGCATTATCGGCGTCGGTCAAGAAGGCGAAGATGTGG TAGATGTAGTCGGTTGGCGCTTAGACGATGTCGTTCAACTGATTAAAGGACCTAAAGGTAGCAAGGTGAAACTGCTCGTG TTACCTGAAGGCAAAGACGCAAAAAGTCACGTTGTCACTATTGTGCGAGATAAAATTCGCTTAGAAGATCGCGCCGTAAA ATCTGAAGTGATTGAAAAAGCAGGGAAGAAAATTGGTGTACTAGAAGTACCGAGTTTCTACGTTGGCTTAGCTCAAGACA CGGAAAAACTACTGGCGGAGCTAAAAGCGAAAAAAGTCGACGGCATCATTGTTGATTTACGCAATAACGGTGGTGGTGCA TTAACCGAAGCTACCGCGCTTTCTGGTTTGTTCATTACCAGTGGCCCTGTAGTTCAGGTGCGTGATAGCTATGGTCGAGT CAACGTTAACTCGGATACCGATGGTAGCATTAGCTATAGCGGACCAATGACCGTGCTGATTAACCGCTACAGTGCATCGG CTTCAGAAATCTTTGCTGCCGCAATGCAAGACTATGGCCGCGCGATCATTCTCGGTGAGAACTCATTTGGTAAAGGTACC GTACAGCAGCATCGCTCTCTCAATCATATCTATGATTTGTTTGATAAAGAGCTTGGCTACGTACAATACACGATTCAAAA ATTTTACCGTATTGATGGTGGTAGTACCCAAAACAAAGGTGTCGTCCCTGATATCGCGTATCCAACCGCGATTGCCCCTT CCGAAACAGGGGAAAGTGTTGAAGATAACGCACTACCGTGGGACAGCATTGATAAAGCAAAATATGAGCGTTTGAATAAC TTCAACACCATCATTGCTAGCTTGGAAGCTAAACACCAACAACGTGTCGCGAATGATTTAGAATTTGGTTTTATCGAGCA AGATATTGCGAAATACCGTGCAGAGAAAGATGACAACCTACTTTCGCTGAATGAAAAAGTACGCAAAGAAGAGAGTGCTA AGGCTGATGAAGAGCGCTTAGCTCGCATCAATCAACGCCAAAAAGCGTTAGGTAAATCGACCTATGCGAGCTTGCAAGAT ATACCGAAAGATTATGAAGCACCGGATGCTTATCTCGATGAATCGGTTAACATTATGCTTGACATGATATCGCGATAA
Upstream 100 bases:
>100_bases TTGAAGTCAATAAGGAAGATGTGCGTGTTCAACTTGCCAACGGCCTACAAATGGTTGTGAAAGCGGAGCACTTGCGCGCA TAAAGGAGATACTCCTACGC
Downstream 100 bases:
>100_bases TTCATTGATTTACTTTATCTTTAATCAAAACGGACCTCATGGTCCGTTTTTTTACACTTTTTTAATTCGTAAAATTAATG TGATGAACATCAAATAATTT
Product: carboxy-terminal protease
Products: NA
Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]
Number of amino acids: Translated: 665; Mature: 665
Protein sequence:
>665_residues MKCRSKISLIAASLWLAAFSAQALEAKLKPEDLPLLVPEAQHATAAKRVTSRFTRSHYKQFNLDDQFSQAMFERYLEMLD YSRNIFTQADIDSFKAWSLQLDDQLKAGDNQIAYDLYNLSMEKRFERFQYALSLLDQEMTFDADESIELDRTKSPWPKDL KEINELWRQRVKYDALSLKLAGKEWPEIKETLDKRYNNAIKRLTQTKSEDVFQTYMNAFAREVDPHTSYLSPRNAEQFQS EMNLSLEGIGAVLQMTDDYTIIRSLVAGGPAALSKQLGEGDRIIGVGQEGEDVVDVVGWRLDDVVQLIKGPKGSKVKLLV LPEGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKAGKKIGVLEVPSFYVGLAQDTEKLLAELKAKKVDGIIVDLRNNGGGA LTEATALSGLFITSGPVVQVRDSYGRVNVNSDTDGSISYSGPMTVLINRYSASASEIFAAAMQDYGRAIILGENSFGKGT VQQHRSLNHIYDLFDKELGYVQYTIQKFYRIDGGSTQNKGVVPDIAYPTAIAPSETGESVEDNALPWDSIDKAKYERLNN FNTIIASLEAKHQQRVANDLEFGFIEQDIAKYRAEKDDNLLSLNEKVRKEESAKADEERLARINQRQKALGKSTYASLQD IPKDYEAPDAYLDESVNIMLDMISR
Sequences:
>Translated_665_residues MKCRSKISLIAASLWLAAFSAQALEAKLKPEDLPLLVPEAQHATAAKRVTSRFTRSHYKQFNLDDQFSQAMFERYLEMLD YSRNIFTQADIDSFKAWSLQLDDQLKAGDNQIAYDLYNLSMEKRFERFQYALSLLDQEMTFDADESIELDRTKSPWPKDL KEINELWRQRVKYDALSLKLAGKEWPEIKETLDKRYNNAIKRLTQTKSEDVFQTYMNAFAREVDPHTSYLSPRNAEQFQS EMNLSLEGIGAVLQMTDDYTIIRSLVAGGPAALSKQLGEGDRIIGVGQEGEDVVDVVGWRLDDVVQLIKGPKGSKVKLLV LPEGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKAGKKIGVLEVPSFYVGLAQDTEKLLAELKAKKVDGIIVDLRNNGGGA LTEATALSGLFITSGPVVQVRDSYGRVNVNSDTDGSISYSGPMTVLINRYSASASEIFAAAMQDYGRAIILGENSFGKGT VQQHRSLNHIYDLFDKELGYVQYTIQKFYRIDGGSTQNKGVVPDIAYPTAIAPSETGESVEDNALPWDSIDKAKYERLNN FNTIIASLEAKHQQRVANDLEFGFIEQDIAKYRAEKDDNLLSLNEKVRKEESAKADEERLARINQRQKALGKSTYASLQD IPKDYEAPDAYLDESVNIMLDMISR >Mature_665_residues MKCRSKISLIAASLWLAAFSAQALEAKLKPEDLPLLVPEAQHATAAKRVTSRFTRSHYKQFNLDDQFSQAMFERYLEMLD YSRNIFTQADIDSFKAWSLQLDDQLKAGDNQIAYDLYNLSMEKRFERFQYALSLLDQEMTFDADESIELDRTKSPWPKDL KEINELWRQRVKYDALSLKLAGKEWPEIKETLDKRYNNAIKRLTQTKSEDVFQTYMNAFAREVDPHTSYLSPRNAEQFQS EMNLSLEGIGAVLQMTDDYTIIRSLVAGGPAALSKQLGEGDRIIGVGQEGEDVVDVVGWRLDDVVQLIKGPKGSKVKLLV LPEGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKAGKKIGVLEVPSFYVGLAQDTEKLLAELKAKKVDGIIVDLRNNGGGA LTEATALSGLFITSGPVVQVRDSYGRVNVNSDTDGSISYSGPMTVLINRYSASASEIFAAAMQDYGRAIILGENSFGKGT VQQHRSLNHIYDLFDKELGYVQYTIQKFYRIDGGSTQNKGVVPDIAYPTAIAPSETGESVEDNALPWDSIDKAKYERLNN FNTIIASLEAKHQQRVANDLEFGFIEQDIAKYRAEKDDNLLSLNEKVRKEESAKADEERLARINQRQKALGKSTYASLQD IPKDYEAPDAYLDESVNIMLDMISR
Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]
COG id: COG0793
COG function: function code M; Periplasmic protease
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PDZ (DHR) domain [H]
Homologues:
Organism=Escherichia coli, GI1788134, Length=656, Percent_Identity=57.3170731707317, Blast_Score=772, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001478 - InterPro: IPR005151 - InterPro: IPR004447 - InterPro: IPR020992 [H]
Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]
EC number: =3.4.21.102 [H]
Molecular weight: Translated: 74780; Mature: 74780
Theoretical pI: Translated: 5.01; Mature: 5.01
Prosite motif: PS50106 PDZ
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKCRSKISLIAASLWLAAFSAQALEAKLKPEDLPLLVPEAQHATAAKRVTSRFTRSHYKQ CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHC FNLDDQFSQAMFERYLEMLDYSRNIFTQADIDSFKAWSLQLDDQLKAGDNQIAYDLYNLS CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHCCCCCCEEHHHHHCC MEKRFERFQYALSLLDQEMTFDADESIELDRTKSPWPKDLKEINELWRQRVKYDALSLKL HHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEE AGKEWPEIKETLDKRYNNAIKRLTQTKSEDVFQTYMNAFAREVDPHTSYLSPRNAEQFQS CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH EMNLSLEGIGAVLQMTDDYTIIRSLVAGGPAALSKQLGEGDRIIGVGQEGEDVVDVVGWR HHCCCHHHCCHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHCCC LDDVVQLIKGPKGSKVKLLVLPEGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKAGKKIGV HHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECE LEVPSFYVGLAQDTEKLLAELKAKKVDGIIVDLRNNGGGALTEATALSGLFITSGPVVQV EECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCEEEECCCCEEEE RDSYGRVNVNSDTDGSISYSGPMTVLINRYSASASEIFAAAMQDYGRAIILGENSFGKGT ECCCCEEECCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCH VQQHRSLNHIYDLFDKELGYVQYTIQKFYRIDGGSTQNKGVVPDIAYPTAIAPSETGESV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC EDNALPWDSIDKAKYERLNNFNTIIASLEAKHQQRVANDLEFGFIEQDIAKYRAEKDDNL CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCE LSLNEKVRKEESAKADEERLARINQRQKALGKSTYASLQDIPKDYEAPDAYLDESVNIML EHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHH DMISR HHHCC >Mature Secondary Structure MKCRSKISLIAASLWLAAFSAQALEAKLKPEDLPLLVPEAQHATAAKRVTSRFTRSHYKQ CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHC FNLDDQFSQAMFERYLEMLDYSRNIFTQADIDSFKAWSLQLDDQLKAGDNQIAYDLYNLS CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHCCCCCCEEHHHHHCC MEKRFERFQYALSLLDQEMTFDADESIELDRTKSPWPKDLKEINELWRQRVKYDALSLKL HHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEE AGKEWPEIKETLDKRYNNAIKRLTQTKSEDVFQTYMNAFAREVDPHTSYLSPRNAEQFQS CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH EMNLSLEGIGAVLQMTDDYTIIRSLVAGGPAALSKQLGEGDRIIGVGQEGEDVVDVVGWR HHCCCHHHCCHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHCCC LDDVVQLIKGPKGSKVKLLVLPEGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKAGKKIGV HHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECE LEVPSFYVGLAQDTEKLLAELKAKKVDGIIVDLRNNGGGALTEATALSGLFITSGPVVQV EECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCEEEECCCCEEEE RDSYGRVNVNSDTDGSISYSGPMTVLINRYSASASEIFAAAMQDYGRAIILGENSFGKGT ECCCCEEECCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCH VQQHRSLNHIYDLFDKELGYVQYTIQKFYRIDGGSTQNKGVVPDIAYPTAIAPSETGESV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC EDNALPWDSIDKAKYERLNNFNTIIASLEAKHQQRVANDLEFGFIEQDIAKYRAEKDDNL CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCE LSLNEKVRKEESAKADEERLARINQRQKALGKSTYASLQDIPKDYEAPDAYLDESVNIML EHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHH DMISR HHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]