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The map label for this gene is cheA-1 [H]

Identifier: 227081568

GI number: 227081568

Start: 1444499

End: 1446784

Strand: Reverse

Name: cheA-1 [H]

Synonym: VCM66_1352

Alternate gene names: 227081568

Gene position: 1446784-1444499 (Counterclockwise)

Preceding gene: 227081569

Following gene: 227081567

Centisome position: 50.02

GC content: 46.02

Gene sequence:

>2286_bases
ATGAACCCAATAATGCAAAACTTCATCATCGAGAGCCGAGATTTAATTGAATCCGCGGCACGAGGTCTACTTGCGTTAGA
AGCGAATCCCGATGACAAAGCCATCATTAACGAGTTATTCCGAGAAATACATACCGTAAAGGGAGCCTCAGGTATTCTCG
ATAATATTGCGCCTTTCACCCAATTAGCGCATCGAATGGAAGATTTGATGCAAAAAGTGCGTGATGGACATGTGGCTTTA
AACGGCACAATGCTTGACCTGATGTTGGGCTGCTGCGACCAATTTCTCTTATGGATTGAAGAGTTAGAACAACACCAAGA
GCTCTCAGCAGAGGCGGTATCGATCAGTAAACAGATGATTGCTCAGTTAGCACCTTTAACTCAAGCCGCGCCAACACACA
CGCCTACCCCTGCCGTAGCGGCGCAAGAAGAGACGGCCACCCTATCCATCAGTGAATTAACGGAGCTATTAGGACGAGAT
TGCTTCAACGATGTAGAAGCGCTTTTGGAACATCCCGATGCTTTACTCTTGATTTATACCCCCGATAAACAGTGCTTTTT
CTCTGGGGACGACCCATTGGCTTGGATGCGTAGTGTTGAAAAGGTCTCTTGGCGTAAAGTAGTGCTCATCCCAGATTCTG
AGCCTTTCGATACCTATCAGGCTCAAATGCAGTTTCTGCTGCTGACTCAATCAGCGAAAAAAGACCTAGAGCAGCAACTT
GCTCCGATAGAAGGCCAATACCGCCTTTACCGCATTCAATCGGACAACCTACCCACAGCACCGATTGATCAGCGCACACA
ATATGTCGAGCGAATTGTTAAACAACAAATCGCGTTGCTTAGAGAAGAACAAGTTTCGGAATCCGTACGTGCTGGTACCT
TCTTATCGATTAAAAATCTCTACTGTGCCCTGAGCCAACAAATCAGTGATCGCCCTGCTCCCTTGCCAGAATCTGTCTCG
GCCGATGAACTTATCACCTTGTTTGATAACATTTTACTCTCTTTTGCTCATCGAACCGCCATCATCGATAAATGCGAAAA
TGAACCTGCTCAACCCTCCGCTATCACGGTTAACGAGCAGTTAGACAAGGTGAAGAAAAAACAGATAAAAACACTGAAGG
TGGATCAGGAAAAAGTCGATTTATTGATGGATTTGGTCGGTGAGCTGATTGTTGCGAAAAACTCGATGCAATATCTCGCC
TATCGTGCAGAAAATGAGTTTGGTGTTCGTAAACTTGCACAAGATATTAAAGCAGAACAGAGTGTGATATCGCGTCTTGC
TGAAGACCTACAGTCTGTTGTGATGCAGGTCCGCATGGTACCACTTGCGACCGTTTTTCAACGCTACCCACGCTTGATCC
GCGATATCTCACGCAAACTGGGTAAACAAGTCGATCTGATCATCGAAGGTGAAGACACTGAGGCAGATAAAAGTATTGTT
GAAGATCTCTCCGAACCTTTAGTGCATCTGATCCGTAATGCCCTCGATCACGGAATAGAATCACCCGACATACGTCGCGA
ACAAGGGAAGAATCCAACAGGAAAAATTACTCTAAGCGCTTTTACTCTTGATGATTCTGTCATCATCAAGATGAGTGATG
ATGGTAAAGGCGTTGATGTCGAACGCGTCAAAACCAAAGCTTTGGAACGCGGGTTAGTGGAAGCGAGCAAACTTGAGCGG
ATGAGCCAACAAGAGATTATTCACTTGATCTTTGAACCCGGCTTTTCAACGGTTGAACAAGTCAGTGATCTCTCAGGACG
CGGTGTGGGTATGGATGCAGTTCGTACGGCTATTGAACGCAACGGCGGCACTCTCACACTCTCCTCAGAGCCGGGGAAAG
GCAGTGAAATTACCATGATCCTGCCACTTTCTATGACCATTTCACGCGTCATGATGTTTGAACTTGAGCAGCAGTCCTTT
GCTATTCCCATTGAATCGGTTATCCAAACGTTAAAAATTTCCCGACACAAAGACATTCGCCGTGTAAAAAATCTCGATAC
GTTCATTTTACGCGGTGAAACTGTGCCTATTTTGTATCTCAAGCGTGCGTTTGAGATGAACTCTGCCCAAATTTATCCCG
ACATCCAACCTATTCTTGTTGTCCGTGTGGGTGATGATGTATTGGGACTTGCCGTAGATCGATTACAAGAGGGACAAGAT
GTCATCATCAAACCTCTTGAGGGTGCTTTGGCCACATTCTCCATCTACCGTGGTGCCGCCATTATGGGAGATGGGCGTGT
CCTTTTAGTGCTCGATACTGAGGAGGTAGTAAAACATGCCCGTTGA

Upstream 100 bases:

>100_bases
GACAACAAGGTATTCATATGGGAGCGAACTTGTATATGGTGAAACCTGTGAATCCTGAAGAATTACAACAAACTGTTACC
TTGATGCTTGGGGGGTTGAA

Downstream 100 bases:

>100_bases
ATATAAAAACCGAGTGGCCTATTTAGTCGATCACGTCGGAGTTGAAGAGGCAGAAACATTATTAACATGGATGGAATCGA
CACCAGGGTCTAGTGTTAAT

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 761; Mature: 761

Protein sequence:

>761_residues
MNPIMQNFIIESRDLIESAARGLLALEANPDDKAIINELFREIHTVKGASGILDNIAPFTQLAHRMEDLMQKVRDGHVAL
NGTMLDLMLGCCDQFLLWIEELEQHQELSAEAVSISKQMIAQLAPLTQAAPTHTPTPAVAAQEETATLSISELTELLGRD
CFNDVEALLEHPDALLLIYTPDKQCFFSGDDPLAWMRSVEKVSWRKVVLIPDSEPFDTYQAQMQFLLLTQSAKKDLEQQL
APIEGQYRLYRIQSDNLPTAPIDQRTQYVERIVKQQIALLREEQVSESVRAGTFLSIKNLYCALSQQISDRPAPLPESVS
ADELITLFDNILLSFAHRTAIIDKCENEPAQPSAITVNEQLDKVKKKQIKTLKVDQEKVDLLMDLVGELIVAKNSMQYLA
YRAENEFGVRKLAQDIKAEQSVISRLAEDLQSVVMQVRMVPLATVFQRYPRLIRDISRKLGKQVDLIIEGEDTEADKSIV
EDLSEPLVHLIRNALDHGIESPDIRREQGKNPTGKITLSAFTLDDSVIIKMSDDGKGVDVERVKTKALERGLVEASKLER
MSQQEIIHLIFEPGFSTVEQVSDLSGRGVGMDAVRTAIERNGGTLTLSSEPGKGSEITMILPLSMTISRVMMFELEQQSF
AIPIESVIQTLKISRHKDIRRVKNLDTFILRGETVPILYLKRAFEMNSAQIYPDIQPILVVRVGDDVLGLAVDRLQEGQD
VIIKPLEGALATFSIYRGAAIMGDGRVLLVLDTEEVVKHAR

Sequences:

>Translated_761_residues
MNPIMQNFIIESRDLIESAARGLLALEANPDDKAIINELFREIHTVKGASGILDNIAPFTQLAHRMEDLMQKVRDGHVAL
NGTMLDLMLGCCDQFLLWIEELEQHQELSAEAVSISKQMIAQLAPLTQAAPTHTPTPAVAAQEETATLSISELTELLGRD
CFNDVEALLEHPDALLLIYTPDKQCFFSGDDPLAWMRSVEKVSWRKVVLIPDSEPFDTYQAQMQFLLLTQSAKKDLEQQL
APIEGQYRLYRIQSDNLPTAPIDQRTQYVERIVKQQIALLREEQVSESVRAGTFLSIKNLYCALSQQISDRPAPLPESVS
ADELITLFDNILLSFAHRTAIIDKCENEPAQPSAITVNEQLDKVKKKQIKTLKVDQEKVDLLMDLVGELIVAKNSMQYLA
YRAENEFGVRKLAQDIKAEQSVISRLAEDLQSVVMQVRMVPLATVFQRYPRLIRDISRKLGKQVDLIIEGEDTEADKSIV
EDLSEPLVHLIRNALDHGIESPDIRREQGKNPTGKITLSAFTLDDSVIIKMSDDGKGVDVERVKTKALERGLVEASKLER
MSQQEIIHLIFEPGFSTVEQVSDLSGRGVGMDAVRTAIERNGGTLTLSSEPGKGSEITMILPLSMTISRVMMFELEQQSF
AIPIESVIQTLKISRHKDIRRVKNLDTFILRGETVPILYLKRAFEMNSAQIYPDIQPILVVRVGDDVLGLAVDRLQEGQD
VIIKPLEGALATFSIYRGAAIMGDGRVLLVLDTEEVVKHAR
>Mature_761_residues
MNPIMQNFIIESRDLIESAARGLLALEANPDDKAIINELFREIHTVKGASGILDNIAPFTQLAHRMEDLMQKVRDGHVAL
NGTMLDLMLGCCDQFLLWIEELEQHQELSAEAVSISKQMIAQLAPLTQAAPTHTPTPAVAAQEETATLSISELTELLGRD
CFNDVEALLEHPDALLLIYTPDKQCFFSGDDPLAWMRSVEKVSWRKVVLIPDSEPFDTYQAQMQFLLLTQSAKKDLEQQL
APIEGQYRLYRIQSDNLPTAPIDQRTQYVERIVKQQIALLREEQVSESVRAGTFLSIKNLYCALSQQISDRPAPLPESVS
ADELITLFDNILLSFAHRTAIIDKCENEPAQPSAITVNEQLDKVKKKQIKTLKVDQEKVDLLMDLVGELIVAKNSMQYLA
YRAENEFGVRKLAQDIKAEQSVISRLAEDLQSVVMQVRMVPLATVFQRYPRLIRDISRKLGKQVDLIIEGEDTEADKSIV
EDLSEPLVHLIRNALDHGIESPDIRREQGKNPTGKITLSAFTLDDSVIIKMSDDGKGVDVERVKTKALERGLVEASKLER
MSQQEIIHLIFEPGFSTVEQVSDLSGRGVGMDAVRTAIERNGGTLTLSSEPGKGSEITMILPLSMTISRVMMFELEQQSF
AIPIESVIQTLKISRHKDIRRVKNLDTFILRGETVPILYLKRAFEMNSAQIYPDIQPILVVRVGDDVLGLAVDRLQEGQD
VIIKPLEGALATFSIYRGAAIMGDGRVLLVLDTEEVVKHAR

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=395, Percent_Identity=37.9746835443038, Blast_Score=259, Evalue=4e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85159; Mature: 85159

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIMQNFIIESRDLIESAARGLLALEANPDDKAIINELFREIHTVKGASGILDNIAPFT
CCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QLAHRMEDLMQKVRDGHVALNGTMLDLMLGCCDQFLLWIEELEQHQELSAEAVSISKQMI
HHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLAPLTQAAPTHTPTPAVAAQEETATLSISELTELLGRDCFNDVEALLEHPDALLLIYT
HHHHCHHHCCCCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PDKQCFFSGDDPLAWMRSVEKVSWRKVVLIPDSEPFDTYQAQMQFLLLTQSAKKDLEQQL
CCCCEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
APIEGQYRLYRIQSDNLPTAPIDQRTQYVERIVKQQIALLREEQVSESVRAGTFLSIKNL
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YCALSQQISDRPAPLPESVSADELITLFDNILLSFAHRTAIIDKCENEPAQPSAITVNEQ
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHH
LDKVKKKQIKTLKVDQEKVDLLMDLVGELIVAKNSMQYLAYRAENEFGVRKLAQDIKAEQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCHHHHHHHHHHHHHH
SVISRLAEDLQSVVMQVRMVPLATVFQRYPRLIRDISRKLGKQVDLIIEGEDTEADKSIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
EDLSEPLVHLIRNALDHGIESPDIRREQGKNPTGKITLSAFTLDDSVIIKMSDDGKGVDV
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEEEEECCEEEEEECCCCCCCCH
ERVKTKALERGLVEASKLERMSQQEIIHLIFEPGFSTVEQVSDLSGRGVGMDAVRTAIER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHC
NGGTLTLSSEPGKGSEITMILPLSMTISRVMMFELEQQSFAIPIESVIQTLKISRHKDIR
CCCEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
RVKNLDTFILRGETVPILYLKRAFEMNSAQIYPDIQPILVVRVGDDVLGLAVDRLQEGQD
HHHCCCCEEEECCCCHHHHHHHHHCCCCCEECCCCCEEEEEEECCHHHHHHHHHHHCCCC
VIIKPLEGALATFSIYRGAAIMGDGRVLLVLDTEEVVKHAR
EEEECHHHHHHHHHHHCCEEEECCCEEEEEECHHHHHHCCC
>Mature Secondary Structure
MNPIMQNFIIESRDLIESAARGLLALEANPDDKAIINELFREIHTVKGASGILDNIAPFT
CCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QLAHRMEDLMQKVRDGHVALNGTMLDLMLGCCDQFLLWIEELEQHQELSAEAVSISKQMI
HHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLAPLTQAAPTHTPTPAVAAQEETATLSISELTELLGRDCFNDVEALLEHPDALLLIYT
HHHHCHHHCCCCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PDKQCFFSGDDPLAWMRSVEKVSWRKVVLIPDSEPFDTYQAQMQFLLLTQSAKKDLEQQL
CCCCEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
APIEGQYRLYRIQSDNLPTAPIDQRTQYVERIVKQQIALLREEQVSESVRAGTFLSIKNL
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YCALSQQISDRPAPLPESVSADELITLFDNILLSFAHRTAIIDKCENEPAQPSAITVNEQ
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHH
LDKVKKKQIKTLKVDQEKVDLLMDLVGELIVAKNSMQYLAYRAENEFGVRKLAQDIKAEQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCHHHHHHHHHHHHHH
SVISRLAEDLQSVVMQVRMVPLATVFQRYPRLIRDISRKLGKQVDLIIEGEDTEADKSIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
EDLSEPLVHLIRNALDHGIESPDIRREQGKNPTGKITLSAFTLDDSVIIKMSDDGKGVDV
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEEEEECCEEEEEECCCCCCCCH
ERVKTKALERGLVEASKLERMSQQEIIHLIFEPGFSTVEQVSDLSGRGVGMDAVRTAIER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHC
NGGTLTLSSEPGKGSEITMILPLSMTISRVMMFELEQQSFAIPIESVIQTLKISRHKDIR
CCCEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
RVKNLDTFILRGETVPILYLKRAFEMNSAQIYPDIQPILVVRVGDDVLGLAVDRLQEGQD
HHHCCCCEEEECCCCHHHHHHHHHCCCCCEECCCCCEEEEEEECCHHHHHHHHHHHCCCC
VIIKPLEGALATFSIYRGAAIMGDGRVLLVLDTEEVVKHAR
EEEECHHHHHHHHHHHCCEEEECCCEEEEEECHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]