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The map label for this gene is ltrA [H]

Identifier: 227081561

GI number: 227081561

Start: 1438005

End: 1438955

Strand: Reverse

Name: ltrA [H]

Synonym: VCM66_1345

Alternate gene names: 227081561

Gene position: 1438955-1438005 (Counterclockwise)

Preceding gene: 227081565

Following gene: 227081556

Centisome position: 49.75

GC content: 52.79

Gene sequence:

>951_bases
ATGGGACGCGAAATTGCAAAAATGGGATTACCGATGAAACTTGATGATTTGGCGCTGTTTTTAACCGTGGTGCGTTGTGG
CAGTTTTGCCTTAGCAGCGAAACAGAAATCGATGTCTACCAGCACGCTGAGCCGCCGTATTCAGCAACTTGAACAAGATA
CGGGCAGCATTTTGCTGATCCGCAACAGTAAAGAGTTGGTACTGACCAAAGAAGGTGAACAGCTATTTCACAGCTACGCC
GAGCTGTTTGCCCAAATTGAGCGCAAACAAGAAGAGGTCGAGCAAGCGAAACGAGATTACCGCGGCGAAATCGCGATAAG
TGCACCCGTGTTACCTCTGCGCCACCAATTAACCCCTTTGGCGCTGGAGTTTGCCGAGCTGCATCCGAATGTCACACTGC
GCATGCAAGTTGGCTCAGGGCTCGACTATTTCAGCCAGCGGGATCTGGATATCGCGCTGCGTTTTGGCCCACAGCCGGAG
TCCGACTGGGTAGCGCGTAAACTGGCGCGTAACCCTTCCGTACTCTGTGCCAGTGCTGAGCTTGCTGCCAAACTCAGCAC
AGTAACGCTTACCTTAGCGCATCCCGAGCAGTTAAAAGAGCATCCCCTACTCAGTCTCAACCACAAGCTGCCGTGGATTT
TTCATCACCACAGCGTCGCGCAAAAAGTGCAATTTATTCCGACGGCGCGTTTGTGCTCCGACGAGCTGGACACGATAGTG
CAAGCCACCTTACAAGGCATGGGCATCGCCCGCTTACCAAGAGGATTAATGGAGCCACTCCTGCGTAGCGGTCAGCTCAT
CGAGCTGCTCCCCGAGTGGGAAATTGAAGGCGCAGATGTGTATCTGCTCCATCCGCAGCGCCGTTTTTTACCTGAGCGCA
CTCAAGCCCTGATTGATTACATCATGACGCACTGGTCACGTGTCGCATTCAGTTATTGGCATCAGCCTTAA

Upstream 100 bases:

>100_bases
GGATCAAAATGCATGAGCTCTCTTTCAAGATAAAGTCAAAGGGAATGGATTTGCTGTGGCACAAGATAACCAAATCACAG
CCATCCGAAAATAGGATAGA

Downstream 100 bases:

>100_bases
CAGCACCAAGCGACTGTGATGAACGATGACGCCGGCAGCGCTCCGAACAATATTTGACTTCATCCCAACACTGCTGCCAT
TTTTTACGCCAAGCAAAAGG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MGREIAKMGLPMKLDDLALFLTVVRCGSFALAAKQKSMSTSTLSRRIQQLEQDTGSILLIRNSKELVLTKEGEQLFHSYA
ELFAQIERKQEEVEQAKRDYRGEIAISAPVLPLRHQLTPLALEFAELHPNVTLRMQVGSGLDYFSQRDLDIALRFGPQPE
SDWVARKLARNPSVLCASAELAAKLSTVTLTLAHPEQLKEHPLLSLNHKLPWIFHHHSVAQKVQFIPTARLCSDELDTIV
QATLQGMGIARLPRGLMEPLLRSGQLIELLPEWEIEGADVYLLHPQRRFLPERTQALIDYIMTHWSRVAFSYWHQP

Sequences:

>Translated_316_residues
MGREIAKMGLPMKLDDLALFLTVVRCGSFALAAKQKSMSTSTLSRRIQQLEQDTGSILLIRNSKELVLTKEGEQLFHSYA
ELFAQIERKQEEVEQAKRDYRGEIAISAPVLPLRHQLTPLALEFAELHPNVTLRMQVGSGLDYFSQRDLDIALRFGPQPE
SDWVARKLARNPSVLCASAELAAKLSTVTLTLAHPEQLKEHPLLSLNHKLPWIFHHHSVAQKVQFIPTARLCSDELDTIV
QATLQGMGIARLPRGLMEPLLRSGQLIELLPEWEIEGADVYLLHPQRRFLPERTQALIDYIMTHWSRVAFSYWHQP
>Mature_315_residues
GREIAKMGLPMKLDDLALFLTVVRCGSFALAAKQKSMSTSTLSRRIQQLEQDTGSILLIRNSKELVLTKEGEQLFHSYAE
LFAQIERKQEEVEQAKRDYRGEIAISAPVLPLRHQLTPLALEFAELHPNVTLRMQVGSGLDYFSQRDLDIALRFGPQPES
DWVARKLARNPSVLCASAELAAKLSTVTLTLAHPEQLKEHPLLSLNHKLPWIFHHHSVAQKVQFIPTARLCSDELDTIVQ
ATLQGMGIARLPRGLMEPLLRSGQLIELLPEWEIEGADVYLLHPQRRFLPERTQALIDYIMTHWSRVAFSYWHQP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=299, Percent_Identity=28.0936454849498, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=27.0547945205479, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787128, Length=307, Percent_Identity=24.4299674267101, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081978, Length=302, Percent_Identity=25.1655629139073, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=22.7891156462585, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=22.8187919463087, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787589, Length=298, Percent_Identity=24.8322147651007, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788706, Length=260, Percent_Identity=24.6153846153846, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=167, Percent_Identity=28.7425149700599, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787601, Length=175, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789173, Length=266, Percent_Identity=24.0601503759398, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35935; Mature: 35804

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGREIAKMGLPMKLDDLALFLTVVRCGSFALAAKQKSMSTSTLSRRIQQLEQDTGSILLI
CCCCHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
RNSKELVLTKEGEQLFHSYAELFAQIERKQEEVEQAKRDYRGEIAISAPVLPLRHQLTPL
ECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHCCCHH
ALEFAELHPNVTLRMQVGSGLDYFSQRDLDIALRFGPQPESDWVARKLARNPSVLCASAE
HHHHHHHCCCEEEEEEECCCCCCHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECHH
LAAKLSTVTLTLAHPEQLKEHPLLSLNHKLPWIFHHHSVAQKVQFIPTARLCSDELDTIV
HHHEEEEEEEEECCHHHHHHCCCEEECCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHH
QATLQGMGIARLPRGLMEPLLRSGQLIELLPEWEIEGADVYLLHPQRRFLPERTQALIDY
HHHHHCCCHHHCCHHHHHHHHHCCCEEEECCCCCCCCCCEEEECCHHHCCHHHHHHHHHH
IMTHWSRVAFSYWHQP
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GREIAKMGLPMKLDDLALFLTVVRCGSFALAAKQKSMSTSTLSRRIQQLEQDTGSILLI
CCCHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
RNSKELVLTKEGEQLFHSYAELFAQIERKQEEVEQAKRDYRGEIAISAPVLPLRHQLTPL
ECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHCCCHH
ALEFAELHPNVTLRMQVGSGLDYFSQRDLDIALRFGPQPESDWVARKLARNPSVLCASAE
HHHHHHHCCCEEEEEEECCCCCCHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECHH
LAAKLSTVTLTLAHPEQLKEHPLLSLNHKLPWIFHHHSVAQKVQFIPTARLCSDELDTIV
HHHEEEEEEEEECCHHHHHHCCCEEECCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHH
QATLQGMGIARLPRGLMEPLLRSGQLIELLPEWEIEGADVYLLHPQRRFLPERTQALIDY
HHHHHCCCHHHCCHHHHHHHHHCCCEEEECCCCCCCCCCEEEECCHHHCCHHHHHHHHHH
IMTHWSRVAFSYWHQP
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]