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The map label for this gene is 227081521

Identifier: 227081521

GI number: 227081521

Start: 1398155

End: 1398628

Strand: Reverse

Name: 227081521

Synonym: VCM66_1305

Alternate gene names: NA

Gene position: 1398628-1398155 (Counterclockwise)

Preceding gene: 227081522

Following gene: 227081519

Centisome position: 48.35

GC content: 46.62

Gene sequence:

>474_bases
ATGATTCAAATCGGACAAACCTTACCAGATGTTCAACTGAGCCAAAGAACCAGTGAGGGTACACTGACTCACTCTGTAAC
CACTTTGTTTGCTAACAAAAAAGTCGTACTGTTTGCCGTTCCGGGTGCCTTCACCCCGACTTGCTCAGAAGCACATCTAC
CTGGCTATGTCGTCTTGGCAGACAAATATAAAGAGAAAGGCGTCGATATGATCGCTTGCGTTTCAGTTAACGATGCTTTT
GTGATGAAAGCATGGGGCGAAGCGCAAAATGCGAGCGAAATTACCATGCTGGCTGATGGCGACGCGAGCTTTACTAAAGC
CTTAGGTCTCGAAATGGACACAGGTAACTTTGGTGGCGTGCGCTCGCAACGCTACGCCATGGTGATTGAAAATAACGTAG
TCACTCTGCTCAATGTTGAGCCACCAAAAACCTTTGAACTGAGCAAAGCAGAAACTGTACTAGCCAGTTTGTAA

Upstream 100 bases:

>100_bases
GTATTTGTTTGCTCGATAAGGGGCTACACTACGGCTAGACTCATTCCGAGCTAGGGCTCGAAATCGTGTAGAGATATACC
ACCTTCATAAGGAAAACATA

Downstream 100 bases:

>100_bases
TTCTAGTCCTCAAAAACCCGACACTGGGTCTTTTGACCGCGTGTCGGGTTGATCGCCTTTCTTGAACAACTCTCGTTGCA
AACCTTGAACACTATTACTT

Product: putative antioxidant

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MIQIGQTLPDVQLSQRTSEGTLTHSVTTLFANKKVVLFAVPGAFTPTCSEAHLPGYVVLADKYKEKGVDMIACVSVNDAF
VMKAWGEAQNASEITMLADGDASFTKALGLEMDTGNFGGVRSQRYAMVIENNVVTLLNVEPPKTFELSKAETVLASL

Sequences:

>Translated_157_residues
MIQIGQTLPDVQLSQRTSEGTLTHSVTTLFANKKVVLFAVPGAFTPTCSEAHLPGYVVLADKYKEKGVDMIACVSVNDAF
VMKAWGEAQNASEITMLADGDASFTKALGLEMDTGNFGGVRSQRYAMVIENNVVTLLNVEPPKTFELSKAETVLASL
>Mature_157_residues
MIQIGQTLPDVQLSQRTSEGTLTHSVTTLFANKKVVLFAVPGAFTPTCSEAHLPGYVVLADKYKEKGVDMIACVSVNDAF
VMKAWGEAQNASEITMLADGDASFTKALGLEMDTGNFGGVRSQRYAMVIENNVVTLLNVEPPKTFELSKAETVLASL

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=147, Percent_Identity=43.5374149659864, Blast_Score=119, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6323138, Length=132, Percent_Identity=38.6363636363636, Blast_Score=93, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706776, Length=146, Percent_Identity=50.6849315068493, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI78709078, Length=146, Percent_Identity=50.6849315068493, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR011906
- InterPro:   IPR014025
- InterPro:   IPR013740
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin; PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 16861; Mature: 16861

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQIGQTLPDVQLSQRTSEGTLTHSVTTLFANKKVVLFAVPGAFTPTCSEAHLPGYVVLA
CEECCCCCCCCEECCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCEEEEEE
DKYKEKGVDMIACVSVNDAFVMKAWGEAQNASEITMLADGDASFTKALGLEMDTGNFGGV
CCCCCCCCCEEEEEECCCEEEEEECCCCCCCCEEEEEECCCCCHHHEECCEECCCCCCCC
RSQRYAMVIENNVVTLLNVEPPKTFELSKAETVLASL
CCCEEEEEEECCEEEEEECCCCCCEECCHHHHHHHCC
>Mature Secondary Structure
MIQIGQTLPDVQLSQRTSEGTLTHSVTTLFANKKVVLFAVPGAFTPTCSEAHLPGYVVLA
CEECCCCCCCCEECCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCEEEEEE
DKYKEKGVDMIACVSVNDAFVMKAWGEAQNASEITMLADGDASFTKALGLEMDTGNFGGV
CCCCCCCCCEEEEEECCCEEEEEECCCCCCCCEEEEEECCCCCHHHEECCEECCCCCCCC
RSQRYAMVIENNVVTLLNVEPPKTFELSKAETVLASL
CCCEEEEEEECCEEEEEECCCCCCEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]