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The map label for this gene is mglA [H]

Identifier: 227081498

GI number: 227081498

Start: 1367663

End: 1369207

Strand: Direct

Name: mglA [H]

Synonym: VCM66_1282

Alternate gene names: 227081498

Gene position: 1367663-1369207 (Clockwise)

Preceding gene: 227081496

Following gene: 227081499

Centisome position: 47.28

GC content: 46.28

Gene sequence:

>1545_bases
GTGTTGTCTGAATTTTTGCATAATAAAAGTGATGCCATGGTCAATCAAACACATGAATTCCTGTTGGAAATGACAGGGGT
GAGTAAAGAGTTCCCCGGAGTGAAAGCTCTGGATAAGGTGAATTTAAAAGTGCGTCCGCATTCGGTTCATGCCTTGATGG
GTGAAAATGGCGCAGGCAAATCCACCTTGTTGAAATGCTTATTTGGTATTTATGAGAAAGATGAAGGCGATATCATTTTT
CTTGGCCAGCATGTGAACTTTTCCTCATCAAAAGAGGCGCTGGAATCCGGTGTCTCTATGGTTCACCAAGAGTTGAACCA
AGTAAAACAGTGCTCGGTGATGGATAATATTTGGCTTGGCCGTTATCCCACCAAAGGATTTTTTGTCGATCACGACAAAA
TGTATCGGGATACCAAAGCGATTTTTGCCGAACTCGATATTGATATCGATCCGAAGGTCAAAGTCGCGACCTTGTCGGTT
TCACAGATGCAGATGCTCGAGATCGCCAAAGCGTTTTCCTACGATGCCAAAGTGGTGATCATGGATGAACCTACCTCATC
CCTGACCGAAAAAGAGGTAAACCATCTTTTTACCATCATCAAAAAGCTCAAAGAAAAAGGCTGTGGGGTGGTGTACATCT
CGCACAAAATGGAAGAGATCTTTTCTATTTGCGATGAGATCACCATTTTGCGTGATGGCCAGTGGGTCGATACGCGTCCG
TTGAAAGGGTTGGACATGGACAAGATCATTTCGATGATGGTTGGCCGTGAACTGACCCAGCGTTTCCCTGAAAAAAGCAA
CGAACCGAAGAATGTCATTCTTGAGGTGAAGAATCTCACCGCACTCAATCAACCCTCGATTCAAGATATTTCGTTTGAAC
TACGAGCTGGGGAAATTTTGGGCGTGGCGGGTCTCGTCGGTTCGCGCCGTACCGACATTGTGGAGACCATTTTTGGTGTG
CGTGAACGCAGTGCCGGACATATTCTGCTCCATGGTCGTGAAATGAAAAATCACGATGCGCATGAAGCGATCAGAAACGG
TTTTGCACTCGTGACCGAAGAGCGCCGCTCGACGGGGATTTACTCCAATCTCGACATCACTTTTAACTCGTTAGTTGCCA
ACGTGGACGAGTACAAAACGCCTTACGGTCTACTCAGTGACAAGAAGATGAAAAGTGATACGCAATGGGTGATTGATTCT
ATGCGGGTGAAAACCCCGTCGCATCAAACTCATATCGGTTCGCTTTCCGGTGGTAACCAGCAAAAAGTCATCATCGGGCG
CTGGCTGCTGACTCAACCCGAGATTTTGATGTTGGATGAACCGACACGCGGTATTGATGTGGGCGCAAAGTACGAAATTT
ATCAGCTGATTTTAGAGCTGGCCAAGAAAGACAAAGGCATCATCATTATTTCCTCTGAGATGCCGGAACTGCTCGGAATT
ACCGACCGGATCATGGTGATGAGCAACGGCCGCAATGCAGGCATTGTGAATACCAAACAAACTTCTCAGAACGAAATTCT
AGAACTGGCCTCTCGATACCTCTAA

Upstream 100 bases:

>100_bases
AAGTAATTTGGATATATTTTTGCAACATCGAAAGATTCAGCGACAGATCAACGGATTTGCCGCACAGAGATATCACGCCG
TGTGTACCACGCATTGATAT

Downstream 100 bases:

>100_bases
GGAAATGACTATGGATGCTGTCAAATCATTTGCAATTAAACATTTAAAAGAGGGCGCAATCTACGCAGTGCTGTTTATTC
TGCTGGCGATTATTGTGATT

Product: galactose/methyl galaxtoside transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MLSEFLHNKSDAMVNQTHEFLLEMTGVSKEFPGVKALDKVNLKVRPHSVHALMGENGAGKSTLLKCLFGIYEKDEGDIIF
LGQHVNFSSSKEALESGVSMVHQELNQVKQCSVMDNIWLGRYPTKGFFVDHDKMYRDTKAIFAELDIDIDPKVKVATLSV
SQMQMLEIAKAFSYDAKVVIMDEPTSSLTEKEVNHLFTIIKKLKEKGCGVVYISHKMEEIFSICDEITILRDGQWVDTRP
LKGLDMDKIISMMVGRELTQRFPEKSNEPKNVILEVKNLTALNQPSIQDISFELRAGEILGVAGLVGSRRTDIVETIFGV
RERSAGHILLHGREMKNHDAHEAIRNGFALVTEERRSTGIYSNLDITFNSLVANVDEYKTPYGLLSDKKMKSDTQWVIDS
MRVKTPSHQTHIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKYEIYQLILELAKKDKGIIIISSEMPELLGI
TDRIMVMSNGRNAGIVNTKQTSQNEILELASRYL

Sequences:

>Translated_514_residues
MLSEFLHNKSDAMVNQTHEFLLEMTGVSKEFPGVKALDKVNLKVRPHSVHALMGENGAGKSTLLKCLFGIYEKDEGDIIF
LGQHVNFSSSKEALESGVSMVHQELNQVKQCSVMDNIWLGRYPTKGFFVDHDKMYRDTKAIFAELDIDIDPKVKVATLSV
SQMQMLEIAKAFSYDAKVVIMDEPTSSLTEKEVNHLFTIIKKLKEKGCGVVYISHKMEEIFSICDEITILRDGQWVDTRP
LKGLDMDKIISMMVGRELTQRFPEKSNEPKNVILEVKNLTALNQPSIQDISFELRAGEILGVAGLVGSRRTDIVETIFGV
RERSAGHILLHGREMKNHDAHEAIRNGFALVTEERRSTGIYSNLDITFNSLVANVDEYKTPYGLLSDKKMKSDTQWVIDS
MRVKTPSHQTHIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKYEIYQLILELAKKDKGIIIISSEMPELLGI
TDRIMVMSNGRNAGIVNTKQTSQNEILELASRYL
>Mature_514_residues
MLSEFLHNKSDAMVNQTHEFLLEMTGVSKEFPGVKALDKVNLKVRPHSVHALMGENGAGKSTLLKCLFGIYEKDEGDIIF
LGQHVNFSSSKEALESGVSMVHQELNQVKQCSVMDNIWLGRYPTKGFFVDHDKMYRDTKAIFAELDIDIDPKVKVATLSV
SQMQMLEIAKAFSYDAKVVIMDEPTSSLTEKEVNHLFTIIKKLKEKGCGVVYISHKMEEIFSICDEITILRDGQWVDTRP
LKGLDMDKIISMMVGRELTQRFPEKSNEPKNVILEVKNLTALNQPSIQDISFELRAGEILGVAGLVGSRRTDIVETIFGV
RERSAGHILLHGREMKNHDAHEAIRNGFALVTEERRSTGIYSNLDITFNSLVANVDEYKTPYGLLSDKKMKSDTQWVIDS
MRVKTPSHQTHIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKYEIYQLILELAKKDKGIIIISSEMPELLGI
TDRIMVMSNGRNAGIVNTKQTSQNEILELASRYL

Specific function: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system [H]

COG id: COG1129

COG function: function code G; ABC-type sugar transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI105990541, Length=227, Percent_Identity=25.9911894273128, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI47078218, Length=231, Percent_Identity=24.2424242424242, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI45446740, Length=231, Percent_Identity=24.2424242424242, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI9961252, Length=262, Percent_Identity=25.5725190839695, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4505771, Length=262, Percent_Identity=25.5725190839695, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI42741659, Length=216, Percent_Identity=27.3148148148148, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21536376, Length=230, Percent_Identity=23.9130434782609, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI9961250, Length=269, Percent_Identity=24.907063197026, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI11967971, Length=213, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI153792144, Length=223, Percent_Identity=24.6636771300448, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1788472, Length=496, Percent_Identity=77.8225806451613, Blast_Score=824, Evalue=0.0,
Organism=Escherichia coli, GI1790190, Length=496, Percent_Identity=43.1451612903226, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1789991, Length=502, Percent_Identity=41.2350597609562, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1790525, Length=501, Percent_Identity=41.3173652694611, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1788210, Length=491, Percent_Identity=38.4928716904277, Blast_Score=360, Evalue=1e-100,
Organism=Escherichia coli, GI1788897, Length=468, Percent_Identity=38.6752136752137, Blast_Score=338, Evalue=7e-94,
Organism=Escherichia coli, GI48995001, Length=499, Percent_Identity=35.0701402805611, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1787792, Length=486, Percent_Identity=32.5102880658436, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI145693107, Length=508, Percent_Identity=23.6220472440945, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI48994943, Length=492, Percent_Identity=21.9512195121951, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789864, Length=226, Percent_Identity=25.6637168141593, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788506, Length=495, Percent_Identity=21.8181818181818, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082268, Length=222, Percent_Identity=23.8738738738739, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786319, Length=231, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786398, Length=224, Percent_Identity=24.1071428571429, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1787029, Length=200, Percent_Identity=27, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786345, Length=213, Percent_Identity=28.6384976525822, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI48994883, Length=230, Percent_Identity=27.8260869565217, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788225, Length=234, Percent_Identity=26.0683760683761, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787712, Length=216, Percent_Identity=24.0740740740741, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789593, Length=217, Percent_Identity=24.8847926267281, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786654, Length=211, Percent_Identity=29.3838862559242, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081791, Length=222, Percent_Identity=26.5765765765766, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790544, Length=227, Percent_Identity=25.9911894273128, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081709, Length=218, Percent_Identity=25.2293577981651, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789672, Length=250, Percent_Identity=23.6, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48994997, Length=231, Percent_Identity=25.974025974026, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790739, Length=206, Percent_Identity=27.1844660194175, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787089, Length=221, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788165, Length=206, Percent_Identity=24.7572815533981, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786872, Length=223, Percent_Identity=25.5605381165919, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788644, Length=188, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786803, Length=189, Percent_Identity=28.042328042328, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87081782, Length=222, Percent_Identity=26.5765765765766, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787370, Length=215, Percent_Identity=23.2558139534884, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786563, Length=216, Percent_Identity=25.462962962963, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788450, Length=219, Percent_Identity=26.9406392694064, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786975, Length=435, Percent_Identity=22.5287356321839, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787758, Length=210, Percent_Identity=24.7619047619048, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786253, Length=187, Percent_Identity=27.807486631016, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789873, Length=211, Percent_Identity=26.5402843601896, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787500, Length=215, Percent_Identity=24.6511627906977, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789032, Length=212, Percent_Identity=27.3584905660377, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787759, Length=245, Percent_Identity=27.3469387755102, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787164, Length=226, Percent_Identity=24.7787610619469, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790162, Length=233, Percent_Identity=29.1845493562232, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790467, Length=212, Percent_Identity=24.5283018867925, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1787105, Length=227, Percent_Identity=21.1453744493392, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=276, Percent_Identity=24.2753623188406, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25146777, Length=214, Percent_Identity=26.6355140186916, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=216, Percent_Identity=24.537037037037, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=203, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=210, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324314, Length=567, Percent_Identity=20.8112874779541, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550390, Length=205, Percent_Identity=26.8292682926829, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666092, Length=244, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571209, Length=219, Percent_Identity=26.9406392694064, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015862
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.17 [H]

Molecular weight: Translated: 57803; Mature: 57803

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00878 ODR_DC_2_1 ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEFLHNKSDAMVNQTHEFLLEMTGVSKEFPGVKALDKVNLKVRPHSVHALMGENGAGK
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCEEEECCCCEEEEECCCCCCH
STLLKCLFGIYEKDEGDIIFLGQHVNFSSSKEALESGVSMVHQELNQVKQCSVMDNIWLG
HHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RYPTKGFFVDHDKMYRDTKAIFAELDIDIDPKVKVATLSVSQMQMLEIAKAFSYDAKVVI
CCCCCCEEECHHHHHHHHHHHHEEECCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCEEEE
MDEPTSSLTEKEVNHLFTIIKKLKEKGCGVVYISHKMEEIFSICDEITILRDGQWVDTRP
EECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHEEEEECCCEECCCC
LKGLDMDKIISMMVGRELTQRFPEKSNEPKNVILEVKNLTALNQPSIQDISFELRAGEIL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCEE
GVAGLVGSRRTDIVETIFGVRERSAGHILLHGREMKNHDAHEAIRNGFALVTEERRSTGI
EEHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCEEEEEECHHCCCC
YSNLDITFNSLVANVDEYKTPYGLLSDKKMKSDTQWVIDSMRVKTPSHQTHIGSLSGGNQ
EEECCEEHHHHHHCHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCCCCCCEECCCCCCCC
QKVIIGRWLLTQPEILMLDEPTRGIDVGAKYEIYQLILELAKKDKGIIIISSEMPELLGI
CEEEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHCC
TDRIMVMSNGRNAGIVNTKQTSQNEILELASRYL
CEEEEEEECCCCCCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLSEFLHNKSDAMVNQTHEFLLEMTGVSKEFPGVKALDKVNLKVRPHSVHALMGENGAGK
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCEEEECCCCEEEEECCCCCCH
STLLKCLFGIYEKDEGDIIFLGQHVNFSSSKEALESGVSMVHQELNQVKQCSVMDNIWLG
HHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RYPTKGFFVDHDKMYRDTKAIFAELDIDIDPKVKVATLSVSQMQMLEIAKAFSYDAKVVI
CCCCCCEEECHHHHHHHHHHHHEEECCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCEEEE
MDEPTSSLTEKEVNHLFTIIKKLKEKGCGVVYISHKMEEIFSICDEITILRDGQWVDTRP
EECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHEEEEECCCEECCCC
LKGLDMDKIISMMVGRELTQRFPEKSNEPKNVILEVKNLTALNQPSIQDISFELRAGEIL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCEE
GVAGLVGSRRTDIVETIFGVRERSAGHILLHGREMKNHDAHEAIRNGFALVTEERRSTGI
EEHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCEEEEEECHHCCCC
YSNLDITFNSLVANVDEYKTPYGLLSDKKMKSDTQWVIDSMRVKTPSHQTHIGSLSGGNQ
EEECCEEHHHHHHCHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCCCCCCEECCCCCCCC
QKVIIGRWLLTQPEILMLDEPTRGIDVGAKYEIYQLILELAKKDKGIIIISSEMPELLGI
CEEEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHCC
TDRIMVMSNGRNAGIVNTKQTSQNEILELASRYL
CEEEEEEECCCCCCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]