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The map label for this gene is mcpB [H]

Identifier: 227081460

GI number: 227081460

Start: 1324039

End: 1325934

Strand: Direct

Name: mcpB [H]

Synonym: VCM66_1244

Alternate gene names: 227081460

Gene position: 1324039-1325934 (Clockwise)

Preceding gene: 227081458

Following gene: 227081463

Centisome position: 45.77

GC content: 48.84

Gene sequence:

>1896_bases
TTGTTTGACATAATGAAATTAACACTAAAACACAAACTGATTGGCGCAAGTTTATCGGCAGTGGTGGTGATGGCGACGGC
ATTGACTTGGTTTTCCGCCAGTCAATTGCAACAGCAAACCAGCAATGCGGTTTATACTCGTGCTGACGCAATTTCTTCGA
CCGCTGCTAAAGGCATCTCAGATTGGATTTCTATCCGTAAATCAATTAGTACTGCGTTTAATGCTCACATTGAAGCACAA
AATGTTGTCCCTTATCTGCAACAAGCGCGCAATGCGGGTGGTTTTGACGATATTTTTTACGGTACGACTGACGGCGCGAT
GTATCGCTCACATCCAGAGCGTAATCGTGCGGATTACGATCCACGTACGCGCCCTTGGTATAAAGATGCAGCCAGTGCGG
GTAAGCAGATCATCACCACCGCATACAGTGATGCGATAACCGGCGCACTGCTTGTGACGATTGCAGAACCTGTTCGCCTT
AACGGTAATATGAGTGGTGTAGTTGGCGCAGATGTTCTCATTGATCAGCTGATTGCGGACGTGATCAGCATGGACGCAGG
AAAAAATGCACAAACCATGTTGATTGATGGTCAAAACGGTTCGTTCCTAGCGCATCCAGACAAATCCTTGCTACTGAAGC
CTGTGACGACGCTCTCTTCTGCTTTGGACATGCGCACTATCGAGCGTGCTGCGAATCAAGGTGAGTTGCTTGCGCTTAAA
CTGAATGGCGTGGAGAAGTTCTTCTTTTTCACTGCGGTACCCGATACACCTTGGTATTTCGCAGTACAGATGGACAGTGA
TACCGAATACGCCTCTCATTCTGAGTTATTAACAGGCCTTATCACTACTGCGTTACTGATCACTGTGATTGTGGTTGTGA
TTGTCTCTTGGCTCGTTAGCTTCTTGTTCCGTGATTTGGGTCGTGTATCGAAAGCGCTGGAGGAAATTGCCTCTGGTGAT
GCCGATTTGACACAACGTTTAGAACCTCGCAGTGATGATGAAGTCGGACAACTGGCAAGCAACTTCAATACCTTTGTGAG
CAACATGCACACCATGGTACTCAAGTTAAGCCATGTTTCAGCCGCATTGGCGCAGCAGTCGAAAGTGACGGCGGCACAAG
CGGAAGAGCGCAGTAGCCGAATTCGCTTGCAACAAGACGAAATCAATATGGTGGCTACCGCAATTAATGAGATGGCTGCT
GCCACTCAAGAAATTGCGGGTAATGCGGATCACACGGCGCAAAACGCAGGTGAAGCCGTGACGGCGTGTGTCCATGGCGC
GGGTCAAGTCACTCAAACGCAGCGTTCGATTCAATCTTTGGCTGAAGAAGTACAAGTCGCGACCGAAGTTATTCAAGAGC
TGGAAGCACATGGTCACCAAATCAGTACGATTCTGTCGACGATTCAGAACATCGCTGAACAGACCAACCTACTGGCGCTG
AATGCGGCCATTGAAGCTGCCCGTGCGGGTGAGCAAGGACGTGGTTTTGCTGTCGTGGCTGATGAAGTTCGTGTGTTGAG
TCAACGTACCCACGCGTCGACCAAAGAAATCCAGCAGATGATTGAAACGCTGCAAGCCACCACAGGTAAAGCGGTAGGTA
TTATGGACGACAGTCGTCGCCTCGCGGACACCAGTGTTGATGATGCGAATGAAGCTTCGGTTAGCTTGGAGCAGATCCAT
AAAACTGTAGAACGTATCAGTGATATGGCGACGCAAATTGCGTCAGCGGCTGAAGAGCAAGCTTCTGTGACTTCGGAGAT
CACTCGCAATACCGTAGGTATTCGTGATGTTTCAAATGATCTCGCGCAAGAAGCTCACTCCGCTGCTGAACAAGCTGCAG
AGTTGTCTGAACTGTCTCATGAGTTAGAACAAGAGATCCGTCGTTTTAAACTGTAA

Upstream 100 bases:

>100_bases
AGGTTAATTCTGGTCTGTGACAAGTTGTGAGAAAAAATGACAAAACGAGTGCGCTTTAATCGAATAGTGTTTACTATCGC
GACTCCTTCGTTCCAACCTT

Downstream 100 bases:

>100_bases
TGACGTCACTGACAAAGTCAGAGTAAGGAGCGCTTGATGCGCTCCTTTTTCGTTCTTATGTATCTCGTCGTTTCGAGTTT
CGATTCGCGGTCAAAGACCT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MFDIMKLTLKHKLIGASLSAVVVMATALTWFSASQLQQQTSNAVYTRADAISSTAAKGISDWISIRKSISTAFNAHIEAQ
NVVPYLQQARNAGGFDDIFYGTTDGAMYRSHPERNRADYDPRTRPWYKDAASAGKQIITTAYSDAITGALLVTIAEPVRL
NGNMSGVVGADVLIDQLIADVISMDAGKNAQTMLIDGQNGSFLAHPDKSLLLKPVTTLSSALDMRTIERAANQGELLALK
LNGVEKFFFFTAVPDTPWYFAVQMDSDTEYASHSELLTGLITTALLITVIVVVIVSWLVSFLFRDLGRVSKALEEIASGD
ADLTQRLEPRSDDEVGQLASNFNTFVSNMHTMVLKLSHVSAALAQQSKVTAAQAEERSSRIRLQQDEINMVATAINEMAA
ATQEIAGNADHTAQNAGEAVTACVHGAGQVTQTQRSIQSLAEEVQVATEVIQELEAHGHQISTILSTIQNIAEQTNLLAL
NAAIEAARAGEQGRGFAVVADEVRVLSQRTHASTKEIQQMIETLQATTGKAVGIMDDSRRLADTSVDDANEASVSLEQIH
KTVERISDMATQIASAAEEQASVTSEITRNTVGIRDVSNDLAQEAHSAAEQAAELSELSHELEQEIRRFKL

Sequences:

>Translated_631_residues
MFDIMKLTLKHKLIGASLSAVVVMATALTWFSASQLQQQTSNAVYTRADAISSTAAKGISDWISIRKSISTAFNAHIEAQ
NVVPYLQQARNAGGFDDIFYGTTDGAMYRSHPERNRADYDPRTRPWYKDAASAGKQIITTAYSDAITGALLVTIAEPVRL
NGNMSGVVGADVLIDQLIADVISMDAGKNAQTMLIDGQNGSFLAHPDKSLLLKPVTTLSSALDMRTIERAANQGELLALK
LNGVEKFFFFTAVPDTPWYFAVQMDSDTEYASHSELLTGLITTALLITVIVVVIVSWLVSFLFRDLGRVSKALEEIASGD
ADLTQRLEPRSDDEVGQLASNFNTFVSNMHTMVLKLSHVSAALAQQSKVTAAQAEERSSRIRLQQDEINMVATAINEMAA
ATQEIAGNADHTAQNAGEAVTACVHGAGQVTQTQRSIQSLAEEVQVATEVIQELEAHGHQISTILSTIQNIAEQTNLLAL
NAAIEAARAGEQGRGFAVVADEVRVLSQRTHASTKEIQQMIETLQATTGKAVGIMDDSRRLADTSVDDANEASVSLEQIH
KTVERISDMATQIASAAEEQASVTSEITRNTVGIRDVSNDLAQEAHSAAEQAAELSELSHELEQEIRRFKL
>Mature_631_residues
MFDIMKLTLKHKLIGASLSAVVVMATALTWFSASQLQQQTSNAVYTRADAISSTAAKGISDWISIRKSISTAFNAHIEAQ
NVVPYLQQARNAGGFDDIFYGTTDGAMYRSHPERNRADYDPRTRPWYKDAASAGKQIITTAYSDAITGALLVTIAEPVRL
NGNMSGVVGADVLIDQLIADVISMDAGKNAQTMLIDGQNGSFLAHPDKSLLLKPVTTLSSALDMRTIERAANQGELLALK
LNGVEKFFFFTAVPDTPWYFAVQMDSDTEYASHSELLTGLITTALLITVIVVVIVSWLVSFLFRDLGRVSKALEEIASGD
ADLTQRLEPRSDDEVGQLASNFNTFVSNMHTMVLKLSHVSAALAQQSKVTAAQAEERSSRIRLQQDEINMVATAINEMAA
ATQEIAGNADHTAQNAGEAVTACVHGAGQVTQTQRSIQSLAEEVQVATEVIQELEAHGHQISTILSTIQNIAEQTNLLAL
NAAIEAARAGEQGRGFAVVADEVRVLSQRTHASTKEIQQMIETLQATTGKAVGIMDDSRRLADTSVDDANEASVSLEQIH
KTVERISDMATQIASAAEEQASVTSEITRNTVGIRDVSNDLAQEAHSAAEQAAELSELSHELEQEIRRFKL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=358, Percent_Identity=29.0502793296089, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI2367378, Length=319, Percent_Identity=30.7210031347962, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788195, Length=281, Percent_Identity=32.7402135231317, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788194, Length=239, Percent_Identity=34.3096234309623, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1789453, Length=346, Percent_Identity=27.4566473988439, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 68188; Mature: 68188

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDIMKLTLKHKLIGASLSAVVVMATALTWFSASQLQQQTSNAVYTRADAISSTAAKGIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DWISIRKSISTAFNAHIEAQNVVPYLQQARNAGGFDDIFYGTTDGAMYRSHPERNRADYD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCC
PRTRPWYKDAASAGKQIITTAYSDAITGALLVTIAEPVRLNGNMSGVVGADVLIDQLIAD
CCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHH
VISMDAGKNAQTMLIDGQNGSFLAHPDKSLLLKPVTTLSSALDMRTIERAANQGELLALK
HHHCCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LNGVEKFFFFTAVPDTPWYFAVQMDSDTEYASHSELLTGLITTALLITVIVVVIVSWLVS
ECCCEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLFRDLGRVSKALEEIASGDADLTQRLEPRSDDEVGQLASNFNTFVSNMHTMVLKLSHVS
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALAQQSKVTAAQAEERSSRIRLQQDEINMVATAINEMAAATQEIAGNADHTAQNAGEAV
HHHHHHHHHHHHHHHHHHHHCEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TACVHGAGQVTQTQRSIQSLAEEVQVATEVIQELEAHGHQISTILSTIQNIAEQTNLLAL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEHH
NAAIEAARAGEQGRGFAVVADEVRVLSQRTHASTKEIQQMIETLQATTGKAVGIMDDSRR
HHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCH
LADTSVDDANEASVSLEQIHKTVERISDMATQIASAAEEQASVTSEITRNTVGIRDVSND
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LAQEAHSAAEQAAELSELSHELEQEIRRFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFDIMKLTLKHKLIGASLSAVVVMATALTWFSASQLQQQTSNAVYTRADAISSTAAKGIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DWISIRKSISTAFNAHIEAQNVVPYLQQARNAGGFDDIFYGTTDGAMYRSHPERNRADYD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCC
PRTRPWYKDAASAGKQIITTAYSDAITGALLVTIAEPVRLNGNMSGVVGADVLIDQLIAD
CCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHH
VISMDAGKNAQTMLIDGQNGSFLAHPDKSLLLKPVTTLSSALDMRTIERAANQGELLALK
HHHCCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LNGVEKFFFFTAVPDTPWYFAVQMDSDTEYASHSELLTGLITTALLITVIVVVIVSWLVS
ECCCEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLFRDLGRVSKALEEIASGDADLTQRLEPRSDDEVGQLASNFNTFVSNMHTMVLKLSHVS
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALAQQSKVTAAQAEERSSRIRLQQDEINMVATAINEMAAATQEIAGNADHTAQNAGEAV
HHHHHHHHHHHHHHHHHHHHCEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TACVHGAGQVTQTQRSIQSLAEEVQVATEVIQELEAHGHQISTILSTIQNIAEQTNLLAL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEHH
NAAIEAARAGEQGRGFAVVADEVRVLSQRTHASTKEIQQMIETLQATTGKAVGIMDDSRR
HHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCH
LADTSVDDANEASVSLEQIHKTVERISDMATQIASAAEEQASVTSEITRNTVGIRDVSND
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LAQEAHSAAEQAAELSELSHELEQEIRRFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]