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The map label for this gene is ycbL [H]

Identifier: 227081442

GI number: 227081442

Start: 1302805

End: 1303461

Strand: Direct

Name: ycbL [H]

Synonym: VCM66_1225

Alternate gene names: 227081442

Gene position: 1302805-1303461 (Clockwise)

Preceding gene: 227081441

Following gene: 227081444

Centisome position: 45.04

GC content: 51.75

Gene sequence:

>657_bases
ATGTCTTTACAATATCAGGTGGTGCCTGTTACGGCCTTTGCTCAGAACTGCTCTATCGTGTGGTGTGATGAAACCATGGA
AGGCATAGTGGTGGATCCGGGTGGTGATGTGAAACAGCTCGCGATGTTGATCGCGGAGCTAGGCGTAAAAGTAACCCAAC
TGGTACTGACTCATGGTCACCTTGATCACGTTGGTGGTACGCAGTCACTGGCGCAAGCTCTCGGTGGAACTCGGGTTGTC
GGGCCGCACAAAGCGGATAATTTCTGGCTACAAGGGCTCGAAGGGCAAAGCAAAATGTTTGGCTTTCCGCTTACGGAAGC
CTTTGAACCTGATGAGTGGCTCGATGATGGCGATGTGATCCACTTTGGTCAGCAAACTCTGCAAGTTATCCATACTCCCG
GACATACACCAGGTCATGTTGTGCTGTTTAGTGAAGCGGCACGTTTGGCGTTTGTGGGTGATGTGCTGTTTAACGGCAGT
ATTGGCCGTACGGATTTCCCGCAAGGGGATTTCAATACTCTGATTGCGTCTATCAAAAATAAACTCTGGCCGCTTGGCAG
CGATGTCACCTTCATCCCCGGTCATGGCCCCCAATCTACCTTTGGCCGTGAACGTGCCAGCAACCCATTTGTCGCGGACG
AAATGCCGCTCTACTGA

Upstream 100 bases:

>100_bases
TGATACCGGCCCTGTACGCCAATGGGTCGGTGCCTAACTTGTCAAAGGCGGGCGTTAATGACATAGTGCCTGCCAGTTAA
GAATCAGACAGGATAGGTTT

Downstream 100 bases:

>100_bases
AGATCCTCTGGCTCGGCAGCGGCAAGATAGCGCCGAGCCAATCCGACAAACTCTTCTGCACTGCGATCTAAGTCCTGCTC
TGAAATAAAAATATCGTAAC

Product: glyoxylase II family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSLQYQVVPVTAFAQNCSIVWCDETMEGIVVDPGGDVKQLAMLIAELGVKVTQLVLTHGHLDHVGGTQSLAQALGGTRVV
GPHKADNFWLQGLEGQSKMFGFPLTEAFEPDEWLDDGDVIHFGQQTLQVIHTPGHTPGHVVLFSEAARLAFVGDVLFNGS
IGRTDFPQGDFNTLIASIKNKLWPLGSDVTFIPGHGPQSTFGRERASNPFVADEMPLY

Sequences:

>Translated_218_residues
MSLQYQVVPVTAFAQNCSIVWCDETMEGIVVDPGGDVKQLAMLIAELGVKVTQLVLTHGHLDHVGGTQSLAQALGGTRVV
GPHKADNFWLQGLEGQSKMFGFPLTEAFEPDEWLDDGDVIHFGQQTLQVIHTPGHTPGHVVLFSEAARLAFVGDVLFNGS
IGRTDFPQGDFNTLIASIKNKLWPLGSDVTFIPGHGPQSTFGRERASNPFVADEMPLY
>Mature_217_residues
SLQYQVVPVTAFAQNCSIVWCDETMEGIVVDPGGDVKQLAMLIAELGVKVTQLVLTHGHLDHVGGTQSLAQALGGTRVVG
PHKADNFWLQGLEGQSKMFGFPLTEAFEPDEWLDDGDVIHFGQQTLQVIHTPGHTPGHVVLFSEAARLAFVGDVLFNGSI
GRTDFPQGDFNTLIASIKNKLWPLGSDVTFIPGHGPQSTFGRERASNPFVADEMPLY

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=191, Percent_Identity=33.5078534031414, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1787158, Length=216, Percent_Identity=55.5555555555556, Blast_Score=263, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17538952, Length=196, Percent_Identity=30.1020408163265, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221330176, Length=194, Percent_Identity=25.2577319587629, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23624; Mature: 23493

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQYQVVPVTAFAQNCSIVWCDETMEGIVVDPGGDVKQLAMLIAELGVKVTQLVLTHGH
CCCEEEEEEEEECCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHCHHHHHHHHHCCC
LDHVGGTQSLAQALGGTRVVGPHKADNFWLQGLEGQSKMFGFPLTEAFEPDEWLDDGDVI
CCCCCCHHHHHHHHCCCEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEE
HFGQQTLQVIHTPGHTPGHVVLFSEAARLAFVGDVLFNGSIGRTDFPQGDFNTLIASIKN
EECHHEEEEEECCCCCCCEEEEEECCCCCEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHH
KLWPLGSDVTFIPGHGPQSTFGRERASNPFVADEMPLY
HCCCCCCCEEEECCCCCCCHHCHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SLQYQVVPVTAFAQNCSIVWCDETMEGIVVDPGGDVKQLAMLIAELGVKVTQLVLTHGH
CCEEEEEEEEECCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHCHHHHHHHHHCCC
LDHVGGTQSLAQALGGTRVVGPHKADNFWLQGLEGQSKMFGFPLTEAFEPDEWLDDGDVI
CCCCCCHHHHHHHHCCCEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEE
HFGQQTLQVIHTPGHTPGHVVLFSEAARLAFVGDVLFNGSIGRTDFPQGDFNTLIASIKN
EECHHEEEEEECCCCCCCEEEEEECCCCCEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHH
KLWPLGSDVTFIPGHGPQSTFGRERASNPFVADEMPLY
HCCCCCCCEEEECCCCCCCHHCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]