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The map label for this gene is cobT [H]

Identifier: 227081409

GI number: 227081409

Start: 1268890

End: 1269999

Strand: Direct

Name: cobT [H]

Synonym: VCM66_1192

Alternate gene names: 227081409

Gene position: 1268890-1269999 (Clockwise)

Preceding gene: 227081408

Following gene: 227081410

Centisome position: 43.87

GC content: 52.43

Gene sequence:

>1110_bases
GTGAAGGCTTTTGCTTTGTTGTTCAGAGCGAGTAGACTGTGCCGCATTTGTTTTCATGCCTTAAAAAGAAGTAAGGATGC
CCGCATGTTAGATCGCTCATTCAGCGCCGAAATCCAACAACGAATCGATCAAAAAACCAAGCCACTCGGGGCGCTAGGGC
AACTTGAGCGCGTCGCGCATCATTTAGCACTCATCCAAAGCCAAAACCAAGATCAAGCGGTAACTCAACTGGCGATTCAT
CAGCCGACCGTTTTGGTTTTTGCCGCCGATCACGGCATCGCTGCGCAAGGTGTCAGTATTGCGCCAAGCGCAGTGACTGA
GCAAATGGTGCAAAACTTTCTCGCGGGCGGCGCGGCCATCAACTGTTTTTGTCGTACTGAACACGCCGCGATGCGGGTGA
TTGACTGCGGTATTTTGCGAGCTCAGCCCGCTCACGCGGATTTGATTGAGCAGCGTCTCGGTGCGGGCACGCATAATTTG
GCCGAGCAAGCCGCCATGTCTTCAGAGCAGGTGCAAGAGGGAATCGCACTTGGCAAGGCGTTGATTCATCGTGAAGTTGA
GTCGGGCTGTAATCTATTGATGTTTGGTGAGATGGGCATTGGCAATACCAGCAGTGCAGCAGCAATCTTGGCGGCACTCT
CCGGCTTGCCGATTGAAGTGTGTGTTGGACGTGGCACCGGCATTACGGATGAGCAGTACCAACGTAAACGAGCGTTGGTT
ACCCAAGGTGTTGAGCGCTGTTTAGGCGCTGCGCCACAAGATGTCTTGCAGCAAGTTGGCGGGTTTGAAATTGTCCAAAT
GGTCGGGGCATTTATGGGGGCATACGAAAAGCAAACCCCAGTGCTGGTGGACGGTTTTATTGTGACGGTTGCCGCTTATG
TTGCGACCTTAATCGAGCCAAATGTACGAGACTTTTTGCTGTTTGCCCACTGCTCACAAGAAACGGGGCACCGCGCAGTA
TTAGAAATGCTGGCCGCAGAGCCACTGTTGGATTTAGGTTTACGTTTAGGTGAAGGTACCGGAGCTGTGTTGGCGCTGGG
TCTTGTTCGTGCTGCAGTGGAGTTTTACAACCACATGGCCAGTTTTGCTGATGCAGGAGTCACAGTGTAA

Upstream 100 bases:

>100_bases
CTGTAACTCCAAGTAGTGTGGGTATATTGGATGCCGAGACTAATGTCAGACGCGGCGGCAAGTCGTTTGCGCTGAGAGTG
TGGTGTAGTAGGCAAAATAA

Downstream 100 bases:

>100_bases
TGGCGGCCATTTTACGTTATCAACTGGAGCTGTTTTTGCTGGCCGTGAGCTTCTTCTCCCGCATTCCTGTGCCGGTGAGT
TTGCCTTATAGCAGTGAGCG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKAFALLFRASRLCRICFHALKRSKDARMLDRSFSAEIQQRIDQKTKPLGALGQLERVAHHLALIQSQNQDQAVTQLAIH
QPTVLVFAADHGIAAQGVSIAPSAVTEQMVQNFLAGGAAINCFCRTEHAAMRVIDCGILRAQPAHADLIEQRLGAGTHNL
AEQAAMSSEQVQEGIALGKALIHREVESGCNLLMFGEMGIGNTSSAAAILAALSGLPIEVCVGRGTGITDEQYQRKRALV
TQGVERCLGAAPQDVLQQVGGFEIVQMVGAFMGAYEKQTPVLVDGFIVTVAAYVATLIEPNVRDFLLFAHCSQETGHRAV
LEMLAAEPLLDLGLRLGEGTGAVLALGLVRAAVEFYNHMASFADAGVTV

Sequences:

>Translated_369_residues
MKAFALLFRASRLCRICFHALKRSKDARMLDRSFSAEIQQRIDQKTKPLGALGQLERVAHHLALIQSQNQDQAVTQLAIH
QPTVLVFAADHGIAAQGVSIAPSAVTEQMVQNFLAGGAAINCFCRTEHAAMRVIDCGILRAQPAHADLIEQRLGAGTHNL
AEQAAMSSEQVQEGIALGKALIHREVESGCNLLMFGEMGIGNTSSAAAILAALSGLPIEVCVGRGTGITDEQYQRKRALV
TQGVERCLGAAPQDVLQQVGGFEIVQMVGAFMGAYEKQTPVLVDGFIVTVAAYVATLIEPNVRDFLLFAHCSQETGHRAV
LEMLAAEPLLDLGLRLGEGTGAVLALGLVRAAVEFYNHMASFADAGVTV
>Mature_369_residues
MKAFALLFRASRLCRICFHALKRSKDARMLDRSFSAEIQQRIDQKTKPLGALGQLERVAHHLALIQSQNQDQAVTQLAIH
QPTVLVFAADHGIAAQGVSIAPSAVTEQMVQNFLAGGAAINCFCRTEHAAMRVIDCGILRAQPAHADLIEQRLGAGTHNL
AEQAAMSSEQVQEGIALGKALIHREVESGCNLLMFGEMGIGNTSSAAAILAALSGLPIEVCVGRGTGITDEQYQRKRALV
TQGVERCLGAAPQDVLQQVGGFEIVQMVGAFMGAYEKQTPVLVDGFIVTVAAYVATLIEPNVRDFLLFAHCSQETGHRAV
LEMLAAEPLLDLGLRLGEGTGAVLALGLVRAAVEFYNHMASFADAGVTV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=343, Percent_Identity=34.1107871720117, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 39377; Mature: 39377

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFALLFRASRLCRICFHALKRSKDARMLDRSFSAEIQQRIDQKTKPLGALGQLERVAH
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HLALIQSQNQDQAVTQLAIHQPTVLVFAADHGIAAQGVSIAPSAVTEQMVQNFLAGGAAI
HHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHE
NCFCRTEHAAMRVIDCGILRAQPAHADLIEQRLGAGTHNLAEQAAMSSEQVQEGIALGKA
EEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LIHREVESGCNLLMFGEMGIGNTSSAAAILAALSGLPIEVCVGRGTGITDEQYQRKRALV
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
TQGVERCLGAAPQDVLQQVGGFEIVQMVGAFMGAYEKQTPVLVDGFIVTVAAYVATLIEP
HHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCC
NVRDFLLFAHCSQETGHRAVLEMLAAEPLLDLGLRLGEGTGAVLALGLVRAAVEFYNHMA
CHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SFADAGVTV
HHHHCCCCC
>Mature Secondary Structure
MKAFALLFRASRLCRICFHALKRSKDARMLDRSFSAEIQQRIDQKTKPLGALGQLERVAH
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HLALIQSQNQDQAVTQLAIHQPTVLVFAADHGIAAQGVSIAPSAVTEQMVQNFLAGGAAI
HHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHE
NCFCRTEHAAMRVIDCGILRAQPAHADLIEQRLGAGTHNLAEQAAMSSEQVQEGIALGKA
EEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LIHREVESGCNLLMFGEMGIGNTSSAAAILAALSGLPIEVCVGRGTGITDEQYQRKRALV
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
TQGVERCLGAAPQDVLQQVGGFEIVQMVGAFMGAYEKQTPVLVDGFIVTVAAYVATLIEP
HHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCC
NVRDFLLFAHCSQETGHRAVLEMLAAEPLLDLGLRLGEGTGAVLALGLVRAAVEFYNHMA
CHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SFADAGVTV
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]