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The map label for this gene is pta [H]

Identifier: 227081270

GI number: 227081270

Start: 1122905

End: 1125049

Strand: Reverse

Name: pta [H]

Synonym: VCM66_1053

Alternate gene names: 227081270

Gene position: 1125049-1122905 (Counterclockwise)

Preceding gene: 227081271

Following gene: 227081263

Centisome position: 38.9

GC content: 51.79

Gene sequence:

>2145_bases
ATGTCCCGTACTATTATGCTTATCCCAATCAGCGCTGGCGTCGGTCTGACCAGCGTGAGCATGGGTCTCCTGCGCGCCAT
GGAGCGTAAAGGGGTTAGCGTTTCTTTCTATAAGCCTATCGCGCAGCCACGTACTGGCGATGATCAACCTGACCTGACGT
CTACTGTCATGAGCCGCAACAGCGACATCAAGATCGGCCAGCCGATGAGTATGTCTGCCGCCGAGACTCTGATCGGTAGC
GAGAAGATGGACGTTCTGCTGGAAACCGTGGTTGAGCGTTACAACCAGATCAACAAAGATGCAGAAGTGACTCTGATCGA
AGGTCTGGTTCCAACGCGTAAGCACCCTTTTGCTAACCAAGTGAACGCGGAGATCGCCAACACTCTCGGTGCAGAAATTG
TGTTCGTTGCCACTCCGGGTACTGATAACCCAACGCAACTGAAAGAGCGCATTGAAGTCGCGTGCTCTAACTTTGGTGGC
ACCAAGAACAAGAGCATCTCTGGCGTTATCATCAACAAGCTGAATGCCCCTGTTGATGAAGCTGGCCGTACTCGTCCTGA
CCTGTCAGAGATCTTTGATGATGCTGACCATGCGAAACAAGCTAACCTTGAAGTGATGCAGATCTTCAACACCAGCCCAA
TTCGTGTGCTGGGCTGTGTACCATGGAGCATCGACCTGATTGCGACTCGTGCTATCGATATGGCGAAGCACCTGAAAGCT
GAGATCATCAACCAAGGTGATATCAATACTCGTCGTATCAAGAGCATCACTTTCTGTGCTCGCTCTATCCCGAACATGAT
TGAGCACTTCAAACCAGGCTCACTCCTAGTAACCTCCGCTGATCGTCCTGACGTGATTGTGGCTGCGGCACTCGCAGCAA
TGAACGGTGTGGAAATCGGTGCCGTACTGCTGACTGGCGGCTACGACATCCCACGTGAACTGGTTAGCCTATGTAAGCCT
GCTTTTGACACGGGTCTGCCCATTTTCAAAGCGCAAGGTAACACTTGGCAAACGTCGCTGAACCTACAAAGCTTCAGCCT
TGAAGTTCCAGCCGATGACAAAGAGCGTATCGAATTCATCAGCGAACACGTGGCAAGCCACATTGACGGCCCATGGGTAG
ACTCTCTGACTGAAGGTGCGCAAGCGTCTCGTCGCTTGAGCCCACCAGCCTTCCGTTACCAGCTGACTGAATTGGCTCGT
AGCGCGAACAAGCGTATCGTACTGCCAGAAGGTGATGAGCCACGTACTGTGAAAGCAGCTGCTATCTGTGCTGAACGCGG
TATTGCACAGTGTGTACTTCTGGGTAACCCAGAAGAGATCAAGCGTGTTGCTGCTCAGCAAGGTGTTGAACTCGGCTCTG
GTATCGAAATCATCGATCCAAAAGTGGCACAAGAGAAATACGTAGCACGTCTGGTTGAACTGCGTAAGAGCAAAGGCATG
ACTGAAGTGGTGGCGCGCGAGCAACTGGAAGATACCGTTGTTCTCGGCACTATGATGCTTGAGCGTAACGAAGTTGACGG
TCTGGTTTCTGGTGCGGTTCACACCACAGCAAACACCATTCGTCCACCACTACAAATCATCAAGACTGCGCCGAATGCGT
CTCTGGTTTCATCGATCTTCTTTATGCTGCTGCCTGATCAGGTACTGGTATACGGTGACTGTGCGATCAACCCAGATCCA
AACGCAGAGCAACTGGCTGAGATTGCTATCCAGTCTGCCGACTCTGCAGCGGCCTTCGGTATTGAGCCTCGCGTAGCGAT
GATCTCTTACTCGACCGGTACTTCTGGTCAAGGTGCAGACGTTGATAAAGTGCGCGAAGCAACTCGCATCGCCAAAGAAA
AACGTCCAGATCTCGTGATTGATGGCCCTTTGCAATACGACGCGGCAATCATGGAAAACGTAGCGGCTTCTAAAGCGCCT
AACTCGCCAGTGGCAGGTAAAGCGACCGTATTCGTATTCCCAGATCTGAACACAGGTAACACGACTTACAAAGCGGTACA
ACGTTCAGCGGATCTAGTGTCTATCGGTCCTATGCTGCAAGGTATGCGTAAGCCAGTTAACGACCTGTCTCGTGGCGCAT
TGGTTGACGATATCGTCTACACCATCGCCCTGACGGCTATCCAAGCAGGTCAAGAGCAGAAATAA

Upstream 100 bases:

>100_bases
TCATTTAGGGGCTCAGCGTAAGCCTGTCCTGCGTTTGAGCTTTGTCACTTTCAATCTAAGCACCTTAGATTGGTATCAAT
AGTGTTGAGGTACTTTACCA

Downstream 100 bases:

>100_bases
GCGCTAGTCACAGTCATCTTTTCTGGTGATAAATAGGCAAAAGCCCCCGACATTCGGGGGCTTTTTTATGCGCTTTATAG
ATTGCTATCTACCCTTTTCA

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MSRTIMLIPISAGVGLTSVSMGLLRAMERKGVSVSFYKPIAQPRTGDDQPDLTSTVMSRNSDIKIGQPMSMSAAETLIGS
EKMDVLLETVVERYNQINKDAEVTLIEGLVPTRKHPFANQVNAEIANTLGAEIVFVATPGTDNPTQLKERIEVACSNFGG
TKNKSISGVIINKLNAPVDEAGRTRPDLSEIFDDADHAKQANLEVMQIFNTSPIRVLGCVPWSIDLIATRAIDMAKHLKA
EIINQGDINTRRIKSITFCARSIPNMIEHFKPGSLLVTSADRPDVIVAAALAAMNGVEIGAVLLTGGYDIPRELVSLCKP
AFDTGLPIFKAQGNTWQTSLNLQSFSLEVPADDKERIEFISEHVASHIDGPWVDSLTEGAQASRRLSPPAFRYQLTELAR
SANKRIVLPEGDEPRTVKAAAICAERGIAQCVLLGNPEEIKRVAAQQGVELGSGIEIIDPKVAQEKYVARLVELRKSKGM
TEVVAREQLEDTVVLGTMMLERNEVDGLVSGAVHTTANTIRPPLQIIKTAPNASLVSSIFFMLLPDQVLVYGDCAINPDP
NAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGQGADVDKVREATRIAKEKRPDLVIDGPLQYDAAIMENVAASKAP
NSPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQAGQEQK

Sequences:

>Translated_714_residues
MSRTIMLIPISAGVGLTSVSMGLLRAMERKGVSVSFYKPIAQPRTGDDQPDLTSTVMSRNSDIKIGQPMSMSAAETLIGS
EKMDVLLETVVERYNQINKDAEVTLIEGLVPTRKHPFANQVNAEIANTLGAEIVFVATPGTDNPTQLKERIEVACSNFGG
TKNKSISGVIINKLNAPVDEAGRTRPDLSEIFDDADHAKQANLEVMQIFNTSPIRVLGCVPWSIDLIATRAIDMAKHLKA
EIINQGDINTRRIKSITFCARSIPNMIEHFKPGSLLVTSADRPDVIVAAALAAMNGVEIGAVLLTGGYDIPRELVSLCKP
AFDTGLPIFKAQGNTWQTSLNLQSFSLEVPADDKERIEFISEHVASHIDGPWVDSLTEGAQASRRLSPPAFRYQLTELAR
SANKRIVLPEGDEPRTVKAAAICAERGIAQCVLLGNPEEIKRVAAQQGVELGSGIEIIDPKVAQEKYVARLVELRKSKGM
TEVVAREQLEDTVVLGTMMLERNEVDGLVSGAVHTTANTIRPPLQIIKTAPNASLVSSIFFMLLPDQVLVYGDCAINPDP
NAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGQGADVDKVREATRIAKEKRPDLVIDGPLQYDAAIMENVAASKAP
NSPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQAGQEQK
>Mature_713_residues
SRTIMLIPISAGVGLTSVSMGLLRAMERKGVSVSFYKPIAQPRTGDDQPDLTSTVMSRNSDIKIGQPMSMSAAETLIGSE
KMDVLLETVVERYNQINKDAEVTLIEGLVPTRKHPFANQVNAEIANTLGAEIVFVATPGTDNPTQLKERIEVACSNFGGT
KNKSISGVIINKLNAPVDEAGRTRPDLSEIFDDADHAKQANLEVMQIFNTSPIRVLGCVPWSIDLIATRAIDMAKHLKAE
IINQGDINTRRIKSITFCARSIPNMIEHFKPGSLLVTSADRPDVIVAAALAAMNGVEIGAVLLTGGYDIPRELVSLCKPA
FDTGLPIFKAQGNTWQTSLNLQSFSLEVPADDKERIEFISEHVASHIDGPWVDSLTEGAQASRRLSPPAFRYQLTELARS
ANKRIVLPEGDEPRTVKAAAICAERGIAQCVLLGNPEEIKRVAAQQGVELGSGIEIIDPKVAQEKYVARLVELRKSKGMT
EVVAREQLEDTVVLGTMMLERNEVDGLVSGAVHTTANTIRPPLQIIKTAPNASLVSSIFFMLLPDQVLVYGDCAINPDPN
AEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGQGADVDKVREATRIAKEKRPDLVIDGPLQYDAAIMENVAASKAPN
SPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQAGQEQK

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0857

COG function: function code R; BioD-like N-terminal domain of phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=714, Percent_Identity=74.6498599439776, Blast_Score=1110, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=317, Percent_Identity=39.1167192429022, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1788806, Length=346, Percent_Identity=30.635838150289, Blast_Score=172, Evalue=9e-44,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 76893; Mature: 76762

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTIMLIPISAGVGLTSVSMGLLRAMERKGVSVSFYKPIAQPRTGDDQPDLTSTVMSRN
CCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHCCC
SDIKIGQPMSMSAAETLIGSEKMDVLLETVVERYNQINKDAEVTLIEGLVPTRKHPFANQ
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHH
VNAEIANTLGAEIVFVATPGTDNPTQLKERIEVACSNFGGTKNKSISGVIINKLNAPVDE
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHH
AGRTRPDLSEIFDDADHAKQANLEVMQIFNTSPIRVLGCVPWSIDLIATRAIDMAKHLKA
CCCCCCCHHHHHCCHHHHHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
EIINQGDINTRRIKSITFCARSIPNMIEHFKPGSLLVTSADRPDVIVAAALAAMNGVEIG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCEEE
AVLLTGGYDIPRELVSLCKPAFDTGLPIFKAQGNTWQTSLNLQSFSLEVPADDKERIEFI
EEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEEEECEEEEEEECCCCHHHHHHHH
SEHVASHIDGPWVDSLTEGAQASRRLSPPAFRYQLTELARSANKRIVLPEGDEPRTVKAA
HHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHH
AICAERGIAQCVLLGNPEEIKRVAAQQGVELGSGIEIIDPKVAQEKYVARLVELRKSKGM
HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCH
TEVVAREQLEDTVVLGTMMLERNEVDGLVSGAVHTTANTIRPPLQIIKTAPNASLVSSIF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHCCCCHHHHHCCCCHHHHHHHH
FMLLPDQVLVYGDCAINPDPNAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGQGAD
HHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCC
VDKVREATRIAKEKRPDLVIDGPLQYDAAIMENVAASKAPNSPVAGKATVFVFPDLNTGN
HHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQAGQEQK
HHHHHHHHCCCCEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRTIMLIPISAGVGLTSVSMGLLRAMERKGVSVSFYKPIAQPRTGDDQPDLTSTVMSRN
CCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHCCC
SDIKIGQPMSMSAAETLIGSEKMDVLLETVVERYNQINKDAEVTLIEGLVPTRKHPFANQ
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHH
VNAEIANTLGAEIVFVATPGTDNPTQLKERIEVACSNFGGTKNKSISGVIINKLNAPVDE
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHH
AGRTRPDLSEIFDDADHAKQANLEVMQIFNTSPIRVLGCVPWSIDLIATRAIDMAKHLKA
CCCCCCCHHHHHCCHHHHHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
EIINQGDINTRRIKSITFCARSIPNMIEHFKPGSLLVTSADRPDVIVAAALAAMNGVEIG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCEEE
AVLLTGGYDIPRELVSLCKPAFDTGLPIFKAQGNTWQTSLNLQSFSLEVPADDKERIEFI
EEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEEEECEEEEEEECCCCHHHHHHHH
SEHVASHIDGPWVDSLTEGAQASRRLSPPAFRYQLTELARSANKRIVLPEGDEPRTVKAA
HHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHH
AICAERGIAQCVLLGNPEEIKRVAAQQGVELGSGIEIIDPKVAQEKYVARLVELRKSKGM
HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCH
TEVVAREQLEDTVVLGTMMLERNEVDGLVSGAVHTTANTIRPPLQIIKTAPNASLVSSIF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHCCCCHHHHHCCCCHHHHHHHH
FMLLPDQVLVYGDCAINPDPNAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGQGAD
HHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCC
VDKVREATRIAKEKRPDLVIDGPLQYDAAIMENVAASKAPNSPVAGKATVFVFPDLNTGN
HHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQAGQEQK
HHHHHHHHCCCCEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883769; 7918659; 9205837; 9278503; 2536666 [H]