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The map label for this gene is sohB [H]

Identifier: 227081233

GI number: 227081233

Start: 1085141

End: 1086211

Strand: Direct

Name: sohB [H]

Synonym: VCM66_1015

Alternate gene names: 227081233

Gene position: 1085141-1086211 (Clockwise)

Preceding gene: 227081231

Following gene: 227081235

Centisome position: 37.52

GC content: 49.02

Gene sequence:

>1071_bases
ATGAGTCACTTGGAGTTTTTGTTAGATTACGGCCTGTTTTTGGCCAAGATTGTGACTGTGGTAGTCGCATTGGTCGCAGT
ACTAGTGATAGTAAAATCATTGGGCGGACGCAGTGGTGGTGCCAAAGGGGAGTTGGAAATCACCGATCTGACCGAACAGC
ATAAAGAGACGGTTGAGCGTTTAGAGGCTTATCTGCATGACGAAGCGTTTTTAAAAGCGCGCGATAAAGCGGATAAGAAG
AAAGAAAAAGCTGAGCAGAAAAGTCGTGAAAAGTCGCTTAAGCAAGCGGCGAAAGAAGGTGAATTGGAAAGCAAACGCGA
TCCGCATCTGTTTGTGCTTGATTTTCACGGCAGTATTGATGCGAAAGAAGTCGCTTCACTGCGTGAAGAGGTGAGCGCGA
TTTTGGCGGTGGCACAAGCGGGTGATGAAGTGCTGCTGCGTTTGGAAACTGGTGGCGGCATGGTGCATGGTTATGGTTTG
GCATCATCACAACTGGATCGCCTTAAAGCGGCTGGCTTACCGCTGACGATTGCGGTAGATAAAGTTGCAGCTAGCGGCGG
TTATATGATGGCCTGCATCGCTGATAAAATCGTCAGTGCGCCATTTGCGATTGTCGGATCTATCGGTGTGGTGGCTCAGT
TACCAAACTTCCATAAACTGCTGAAAAAGAACGATATCGAGTTTGAACAGCTCACGGCGGGCGAATACAAGCGCACCTTA
ACCATGTTTGGTGAAAACACCGATAAAGCGCGTGAAAAGTTCAAGCAAGAGCTGGAAGAAACACATCAACTGTTCAAAGA
CTTTATCCGTGAGCATCGACCCGCGTTGGATCTCGATAAAGTCGCGACAGGTGAACACTGGTTTGGCACGCAGGCCAAAG
CTCTGGGGTTGGTCGATGAGATTCAAACGTCCGATGATTTGATTGTTGCCGCGTGCAAGAGCAAAACCGTACTTCTGCTG
CGTTATACGCAAAAGAAAAAGCTGGCCGATAAACTGGCCGGAGTGGCCGGTGATGCCGCCGACAATGTGTTGCTGAAACT
GATCAGTCGAGGCCAACGTCCCTTGGTTTAA

Upstream 100 bases:

>100_bases
GAGGCGTGTCAAAAATCCAAGGTTAGTCGAGTTGGAAGAGGATTTGCTTTAAGTCTTCGTGACAAGGTGGTTACAATACA
CCAATTCGTATTCAAGAAGG

Downstream 100 bases:

>100_bases
GGTTGATTGGTTTACTGTTCGTTGCCGTAATGAAAAAACGCGCTTAGTTTGCTAAGCGCGTTTTTTCATGGTCATCCCTA
AATCATCGCTTTTTGCGCTG

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSHLEFLLDYGLFLAKIVTVVVALVAVLVIVKSLGGRSGGAKGELEITDLTEQHKETVERLEAYLHDEAFLKARDKADKK
KEKAEQKSREKSLKQAAKEGELESKRDPHLFVLDFHGSIDAKEVASLREEVSAILAVAQAGDEVLLRLETGGGMVHGYGL
ASSQLDRLKAAGLPLTIAVDKVAASGGYMMACIADKIVSAPFAIVGSIGVVAQLPNFHKLLKKNDIEFEQLTAGEYKRTL
TMFGENTDKAREKFKQELEETHQLFKDFIREHRPALDLDKVATGEHWFGTQAKALGLVDEIQTSDDLIVAACKSKTVLLL
RYTQKKKLADKLAGVAGDAADNVLLKLISRGQRPLV

Sequences:

>Translated_356_residues
MSHLEFLLDYGLFLAKIVTVVVALVAVLVIVKSLGGRSGGAKGELEITDLTEQHKETVERLEAYLHDEAFLKARDKADKK
KEKAEQKSREKSLKQAAKEGELESKRDPHLFVLDFHGSIDAKEVASLREEVSAILAVAQAGDEVLLRLETGGGMVHGYGL
ASSQLDRLKAAGLPLTIAVDKVAASGGYMMACIADKIVSAPFAIVGSIGVVAQLPNFHKLLKKNDIEFEQLTAGEYKRTL
TMFGENTDKAREKFKQELEETHQLFKDFIREHRPALDLDKVATGEHWFGTQAKALGLVDEIQTSDDLIVAACKSKTVLLL
RYTQKKKLADKLAGVAGDAADNVLLKLISRGQRPLV
>Mature_355_residues
SHLEFLLDYGLFLAKIVTVVVALVAVLVIVKSLGGRSGGAKGELEITDLTEQHKETVERLEAYLHDEAFLKARDKADKKK
EKAEQKSREKSLKQAAKEGELESKRDPHLFVLDFHGSIDAKEVASLREEVSAILAVAQAGDEVLLRLETGGGMVHGYGLA
SSQLDRLKAAGLPLTIAVDKVAASGGYMMACIADKIVSAPFAIVGSIGVVAQLPNFHKLLKKNDIEFEQLTAGEYKRTLT
MFGENTDKAREKFKQELEETHQLFKDFIREHRPALDLDKVATGEHWFGTQAKALGLVDEIQTSDDLIVAACKSKTVLLLR
YTQKKKLADKLAGVAGDAADNVLLKLISRGQRPLV

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=353, Percent_Identity=55.5240793201133, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1788064, Length=194, Percent_Identity=26.2886597938144, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 38970; Mature: 38839

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLEFLLDYGLFLAKIVTVVVALVAVLVIVKSLGGRSGGAKGELEITDLTEQHKETVER
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHH
LEAYLHDEAFLKARDKADKKKEKAEQKSREKSLKQAAKEGELESKRDPHLFVLDFHGSID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCC
AKEVASLREEVSAILAVAQAGDEVLLRLETGGGMVHGYGLASSQLDRLKAAGLPLTIAVD
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEEH
KVAASGGYMMACIADKIVSAPFAIVGSIGVVAQLPNFHKLLKKNDIEFEQLTAGEYKRTL
HHHCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHH
TMFGENTDKAREKFKQELEETHQLFKDFIREHRPALDLDKVATGEHWFGTQAKALGLVDE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHH
IQTSDDLIVAACKSKTVLLLRYTQKKKLADKLAGVAGDAADNVLLKLISRGQRPLV
HCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SHLEFLLDYGLFLAKIVTVVVALVAVLVIVKSLGGRSGGAKGELEITDLTEQHKETVER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHH
LEAYLHDEAFLKARDKADKKKEKAEQKSREKSLKQAAKEGELESKRDPHLFVLDFHGSID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCC
AKEVASLREEVSAILAVAQAGDEVLLRLETGGGMVHGYGLASSQLDRLKAAGLPLTIAVD
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEEH
KVAASGGYMMACIADKIVSAPFAIVGSIGVVAQLPNFHKLLKKNDIEFEQLTAGEYKRTL
HHHCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHH
TMFGENTDKAREKFKQELEETHQLFKDFIREHRPALDLDKVATGEHWFGTQAKALGLVDE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHH
IQTSDDLIVAACKSKTVLLLRYTQKKKLADKLAGVAGDAADNVLLKLISRGQRPLV
HCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]