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The map label for this gene is hscB [H]

Identifier: 227080930

GI number: 227080930

Start: 760718

End: 761233

Strand: Direct

Name: hscB [H]

Synonym: VCM66_0709

Alternate gene names: 227080930

Gene position: 760718-761233 (Clockwise)

Preceding gene: 227080929

Following gene: 227080931

Centisome position: 26.3

GC content: 48.06

Gene sequence:

>516_bases
ATGAATTATTTTGAATTATTTGGGCTGCCGATCCAGTTTGAACTGGATGGTAGCCTTCTTTCTTCTCAGTTCAGAGCGTT
GCAGAAACGATTCCATCCGGATAATTTTGCTACCGCTTCTGAGCGTGACCGCCTAATGGCAGTGCAGCAAGCCGCGCAAA
TTAATGATGCGTATCAGACACTGAAAGATTCACTCCGCCGCGCGGAATATCTGTTGTCGTTACAAGGCATAGAGATGAAG
GCTGAGCAGCAGACGCTGCAAGATCCGATGTTTCTGATGGAACAGATGGAGCTACGCGAAGAGCTAGAGTCCGTGACGGC
TTGTGCAGATCCTGAGGCCGCCTTAGTCGCTTTTGACACTAAGGTAACCGCGATGCAGCGTCATTATCTCGCACAGCTAC
AAGGCCAATTAGCTCAAAGTGAGTGGTTAGCGGCGGCTGATCAGATCAGAAAGCTCAAATTTATTGCCAAACTCAAAAAT
GAAGTAGAACGAGTCGAAGACCAACTGCTTGGCTAA

Upstream 100 bases:

>100_bases
CAACCCAAATGTCAAAAGCGAATGTGGTTGTGGTGAAAGCTTCAACGTTTAACGGTAACTGACCATCGAGACTGTTCTCG
ATCACAGGACCGCTATCAAG

Downstream 100 bases:

>100_bases
TTCAAGATTCAAAGGAACAACTGATGGCATTACTTCAGATTGCAGAGCCGGGGCAAAGTTCGGCACCACACCAGCATAAG
TTGGCTGCGGGTATTGATTT

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQTLKDSLRRAEYLLSLQGIEMK
AEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDTKVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKN
EVERVEDQLLG

Sequences:

>Translated_171_residues
MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQTLKDSLRRAEYLLSLQGIEMK
AEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDTKVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKN
EVERVEDQLLG
>Mature_171_residues
MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQTLKDSLRRAEYLLSLQGIEMK
AEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDTKVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKN
EVERVEDQLLG

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=162, Percent_Identity=29.0123456790123, Blast_Score=78, Evalue=5e-15,
Organism=Escherichia coli, GI1788876, Length=172, Percent_Identity=49.4186046511628, Blast_Score=156, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17541320, Length=140, Percent_Identity=30, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161084223, Length=171, Percent_Identity=28.6549707602339, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19632; Mature: 19632

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQT
CCHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKDSLRRAEYLLSLQGIEMKAEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECH
KVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKNEVERVEDQLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQT
CCHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKDSLRRAEYLLSLQGIEMKAEQQTLQDPMFLMEQMELREELESVTACADPEAALVAFDT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECH
KVTAMQRHYLAQLQGQLAQSEWLAAADQIRKLKFIAKLKNEVERVEDQLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA