Click here to switch to the map view.

The map label for this gene is luxS

Identifier: 227080740

GI number: 227080740

Start: 549154

End: 549672

Strand: Direct

Name: luxS

Synonym: VCM66_0515

Alternate gene names: 227080740

Gene position: 549154-549672 (Clockwise)

Preceding gene: 227080739

Following gene: 227080743

Centisome position: 18.99

GC content: 48.55

Gene sequence:

>519_bases
ATGCCATTATTAGACAGTTTTACCGTCGATCATACTCGTATGAATGCACCGGCGGTGCGTGTTGCCAAAACCATGCAAAC
CCCAAAAGGGGATACGATTACCGTATTTGATTTGCGTTTTACTATGCCAAACAAAGATATCTTGTCTGAGCGCGGTATCC
ATACTCTAGAGCATCTCTACGCGGGCTTTATGCGCAATCACCTTAACGGCAGCCAAGTGGAGATCATCGATATTTCACCA
ATGGGTTGCCGTACAGGTTTCTACATGAGCTTGATTGGTGCGCCGACAGAACAGCAAGTGGCACAAGCATGGCTAGCCGC
AATGCAAGATGTGTTGAAAGTTGAAAGCCAAGAGCAAATTCCTGAGCTGAATGAGTACCAGTGCGGCACTGCGGCGATGC
ACTCGCTCGAAGAAGCCAAAGCGATTGCGAAAAACGTGATTGCGGCAGGCATCTCGGTTAACCGTAACGATGAGTTGGCG
CTGCCCGAATCTATGCTCAATGAGCTGAAGGTTCACTAA

Upstream 100 bases:

>100_bases
TTTTGATGCTTACCTAACGCAATATTTTGCCTACCTACAGGCGGTGAGTTAATTTAGTTTTAGTGGTGCGCAGTAAGCGA
GCCAGAAAGGGAGAAAGGAA

Downstream 100 bases:

>100_bases
GTCGGTTCTGTAAACGTTAAAAATACAAAAGCCCGAAGTTGAGTTCGGGCTTTTGTTTGAGTGCTTAACTTAAACCAAGC
TGACTTTGGTTTTTCTTGGG

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTMPNKDILSERGIHTLEHLYAGFMRNHLNGSQVEIIDISP
MGCRTGFYMSLIGAPTEQQVAQAWLAAMQDVLKVESQEQIPELNEYQCGTAAMHSLEEAKAIAKNVIAAGISVNRNDELA
LPESMLNELKVH

Sequences:

>Translated_172_residues
MPLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTMPNKDILSERGIHTLEHLYAGFMRNHLNGSQVEIIDISP
MGCRTGFYMSLIGAPTEQQVAQAWLAAMQDVLKVESQEQIPELNEYQCGTAAMHSLEEAKAIAKNVIAAGISVNRNDELA
LPESMLNELKVH
>Mature_171_residues
PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTMPNKDILSERGIHTLEHLYAGFMRNHLNGSQVEIIDISPM
GCRTGFYMSLIGAPTEQQVAQAWLAAMQDVLKVESQEQIPELNEYQCGTAAMHSLEEAKAIAKNVIAAGISVNRNDELAL
PESMLNELKVH

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=171, Percent_Identity=73.0994152046784, Blast_Score=273, Evalue=6e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_VIBC3 (A5F9A3)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F9A3
- SMR:   A5F9A3
- STRING:   A5F9A3
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0091
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- BioCyc:   VCHO345073:VC0395_A0091-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 19081; Mature: 18950

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTMPNKDILSERGIHTLEHLY
CCCCCCCCCCCHHCCCCHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHCCHHHHHHHH
AGFMRNHLNGSQVEIIDISPMGCRTGFYMSLIGAPTEQQVAQAWLAAMQDVLKVESQEQI
HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHCC
PELNEYQCGTAAMHSLEEAKAIAKNVIAAGISVNRNDELALPESMLNELKVH
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTMPNKDILSERGIHTLEHLY
CCCCCCCCCCHHCCCCHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHCCHHHHHHHH
AGFMRNHLNGSQVEIIDISPMGCRTGFYMSLIGAPTEQQVAQAWLAAMQDVLKVESQEQI
HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHCC
PELNEYQCGTAAMHSLEEAKAIAKNVIAAGISVNRNDELALPESMLNELKVH
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA