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The map label for this gene is accD [H]

Identifier: 226951048

GI number: 226951048

Start: 4107399

End: 4108268

Strand: Reverse

Name: accD [H]

Synonym: CLM_4087

Alternate gene names: 226951048

Gene position: 4108268-4107399 (Counterclockwise)

Preceding gene: 226951049

Following gene: 226951047

Centisome position: 98.87

GC content: 28.97

Gene sequence:

>870_bases
ATGTTAAAAAATTTATTTAGAAAAACAAAGTATATAACTGTAAGTCAAAAGAATATAGGAAATTATAAAAGAGAAAATAC
TCCTACTATTCCAGATGGAATGTGGGTTAAATGTAATAAATGTGGAGAGATATTATACCAAAATGATTTAGAAAAGAATT
ATATGGTATGTAATTTATGTGGAAATCATTTTAGAATAGGTGTTAAAGAAAGAATAAAATATTTATTCGATAAAGATACC
TTTAAAGAATGGGATTATAAAATTAAAACAGAAAATCCATTAGATTTTAAAGGCTACGATGAAAAAATAGAACATATAAA
AGAAAAAACAAACTTAAGTGAAGCTGTTACAACAGGTAAAGGTAAAATAGCTGGTATGGAAGTTGTAGTATGTATAATGG
ATAGTAAATTCATGATGGGAAGTATGGGATCTGTTGTAGGAGAAAAAATAACTAGAGCTATAGAAAGAGCTATAGAGTTA
AGATTGCCAGTTATAATATTTACTGCATCTGGTGGGGCAAGAATGCAGGAAGGAATATTATCTTTAATGCAAATGGCTAA
AGTAAGTTCTGCATTAGCAAAATTAGATGAAGAAGGATTATTATATATATGTGTACTAACAGATCCAACTACAGGAGGGG
TCACAGCTAGTTTTGCTATGCTTGGAGATATAATACTTGCTGAACCAGATGCGTTAATAGGATTTGCAGGTAAGAGGGTA
ATAGAACAAACCATAAATGAAAAGTTACCAGAGGACTTTCAGAAATCTGAATTTTTATTAGAGCATGGTTTTATTGATAA
AATAGTCCCAAGGTCTGATTTAAGAAAAGTTTTAGCAAAGCTTATTAATATGCATCAAAATTCTTTTTAA

Upstream 100 bases:

>100_bases
TTTATTATATTAGAGGATGAAAATTTTATAAAGGGAGAATACACTACAAAATATATAGAAAAAATGCTAACTGACAATTA
GTGTAGTCAGGGGGAAGTAT

Downstream 100 bases:

>100_bases
GATTATACATTAATATTATTTCTTAATTTAGATTGGAGATATAAATATGGAAGATAAAAAATTGATTCATAATGTAAAAA
AATATGCTTCTAAAAATGCT

Product: acetyl-CoA carboxylase, carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MLKNLFRKTKYITVSQKNIGNYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLCGNHFRIGVKERIKYLFDKDT
FKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGKGKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIEL
RLPVIIFTASGGARMQEGILSLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRV
IEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF

Sequences:

>Translated_289_residues
MLKNLFRKTKYITVSQKNIGNYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLCGNHFRIGVKERIKYLFDKDT
FKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGKGKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIEL
RLPVIIFTASGGARMQEGILSLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRV
IEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF
>Mature_289_residues
MLKNLFRKTKYITVSQKNIGNYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLCGNHFRIGVKERIKYLFDKDT
FKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGKGKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIEL
RLPVIIFTASGGARMQEGILSLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRV
IEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=189, Percent_Identity=27.5132275132275, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1788655, Length=277, Percent_Identity=50.1805054151625, Blast_Score=275, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI25147359, Length=190, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25147362, Length=190, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 32654; Mature: 32654

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNLFRKTKYITVSQKNIGNYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLC
CCHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEEC
GNHFRIGVKERIKYLFDKDTFKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGK
CCCEEECHHHHHHHHHCCCCHHCCCEEECCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCC
GKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIELRLPVIIFTASGGARMQEGIL
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
SLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRV
HHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHEECCCHHHHHHHHHH
IEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF
HHHHHHHHCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKNLFRKTKYITVSQKNIGNYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLC
CCHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEEC
GNHFRIGVKERIKYLFDKDTFKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGK
CCCEEECHHHHHHHHHCCCCHHCCCEEECCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCC
GKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIELRLPVIIFTASGGARMQEGIL
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
SLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRV
HHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHEECCCHHHHHHHHHH
IEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF
HHHHHHHHCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA