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The map label for this gene is coaX

Identifier: 226950979

GI number: 226950979

Start: 4032661

End: 4033437

Strand: Reverse

Name: coaX

Synonym: CLM_4008

Alternate gene names: 226950979

Gene position: 4033437-4032661 (Counterclockwise)

Preceding gene: 226950980

Following gene: 226950978

Centisome position: 97.07

GC content: 27.41

Gene sequence:

>777_bases
ATGATTTTAGTTTTAGATGTAGGAAATACTAATATAGTTTTAGGTATATATAAAAATAAAGAATTAATAGCAAACTGGAG
ATTAGCTACAGATAATAAAAGGACAGCAGATGAATATGGAATACAAGTAATAGAATTATTTTCACATAATAATTTAAGTT
TTTCTGATATAGAAGGAGTAATTATATCCTCTGTAGTTCCTAATATAATGTATTCTTTAGAACATATGATATCAAAATAT
TTTAATATAAAACCTATAATAGTAGGACCTGGAGTAAAAACAGGTATAAACATAAAATATGATAATCCAAAGGAAGTTGG
AGCAGATAGAATTGTTAATGCAGTAGCAGCTCATGAAATTTATAAAAAACCATTAATAATTATTGATTTTGGAACAGCTA
CTACATTTTGTGCTGTAACAAAAGAAGCCAATTATTTAGGTGGAACTATATGTCCAGGTATAAAAATTTCTTCAGATGCT
TTATTTGATAAGGCAGCTAAATTACCAAGGGTAGAACTTGTAAAAACTCCTGGAGTTATATGTAAAAATACTGTAGCTAG
TATACAATCTGGAATAATTTATGGTTATGCTGGGCAAGTAGATTATATAGTGTCAAAAATGAAAAAGGAAATGATGGATC
TAGGGGAAGAGGAACCTTTTGTAGTTGCTACAGGAGGCTTTGCTAAATTAATTAGTGAAGAATCAAAAAGTATTGATGAA
ATAAATGCTATTTTAACCTTAGAAGGATTAAGAGTAATATATGAAAAAAATAAATAA

Upstream 100 bases:

>100_bases
AATTATTAAATTGACATTAAATCAAGCATAAAGGGCAGCGGCAAGGCTGCTCTTTCATTGTATTTAAGACCCTATTTTGC
TTATTAAGGTGGTGCTTTAT

Downstream 100 bases:

>100_bases
GGTGATTATATGAATATAGGAAATCTTATATTTCATAATAATGTATTTTTAGCACCTATGGCAGGATTTACAGATATAGC
TTTTAGAGAGATATGTAAAG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MILVLDVGNTNIVLGIYKNKELIANWRLATDNKRTADEYGIQVIELFSHNNLSFSDIEGVIISSVVPNIMYSLEHMISKY
FNIKPIIVGPGVKTGINIKYDNPKEVGADRIVNAVAAHEIYKKPLIIIDFGTATTFCAVTKEANYLGGTICPGIKISSDA
LFDKAAKLPRVELVKTPGVICKNTVASIQSGIIYGYAGQVDYIVSKMKKEMMDLGEEEPFVVATGGFAKLISEESKSIDE
INAILTLEGLRVIYEKNK

Sequences:

>Translated_258_residues
MILVLDVGNTNIVLGIYKNKELIANWRLATDNKRTADEYGIQVIELFSHNNLSFSDIEGVIISSVVPNIMYSLEHMISKY
FNIKPIIVGPGVKTGINIKYDNPKEVGADRIVNAVAAHEIYKKPLIIIDFGTATTFCAVTKEANYLGGTICPGIKISSDA
LFDKAAKLPRVELVKTPGVICKNTVASIQSGIIYGYAGQVDYIVSKMKKEMMDLGEEEPFVVATGGFAKLISEESKSIDE
INAILTLEGLRVIYEKNK
>Mature_258_residues
MILVLDVGNTNIVLGIYKNKELIANWRLATDNKRTADEYGIQVIELFSHNNLSFSDIEGVIISSVVPNIMYSLEHMISKY
FNIKPIIVGPGVKTGINIKYDNPKEVGADRIVNAVAAHEIYKKPLIIIDFGTATTFCAVTKEANYLGGTICPGIKISSDA
LFDKAAKLPRVELVKTPGVICKNTVASIQSGIIYGYAGQVDYIVSKMKKEMMDLGEEEPFVVATGGFAKLISEESKSIDE
INAILTLEGLRVIYEKNK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_CLOB1 (A7FZA9)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385838.1
- ProteinModelPortal:   A7FZA9
- SMR:   A7FZA9
- STRING:   A7FZA9
- GeneID:   5397101
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3597
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   CBOT441770:CLB_3597-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28309; Mature: 28309

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 100-100 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVLDVGNTNIVLGIYKNKELIANWRLATDNKRTADEYGIQVIELFSHNNLSFSDIEGV
CEEEEEECCCEEEEEEECCCEEEEEEEEECCCCCCHHHHCEEEEEEECCCCCCHHHHCHH
IISSVVPNIMYSLEHMISKYFNIKPIIVGPGVKTGINIKYDNPKEVGADRIVNAVAAHEI
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCHHHHCHHHHHHHHHHHHH
YKKPLIIIDFGTATTFCAVTKEANYLGGTICPGIKISSDALFDKAAKLPRVELVKTPGVI
HHCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCEECCHHHHHHHHCCCCEEEECCCCCH
CKNTVASIQSGIIYGYAGQVDYIVSKMKKEMMDLGEEEPFVVATGGFAKLISEESKSIDE
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCHHH
INAILTLEGLRVIYEKNK
HHHEEEECCEEEEEECCC
>Mature Secondary Structure
MILVLDVGNTNIVLGIYKNKELIANWRLATDNKRTADEYGIQVIELFSHNNLSFSDIEGV
CEEEEEECCCEEEEEEECCCEEEEEEEEECCCCCCHHHHCEEEEEEECCCCCCHHHHCHH
IISSVVPNIMYSLEHMISKYFNIKPIIVGPGVKTGINIKYDNPKEVGADRIVNAVAAHEI
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCHHHHCHHHHHHHHHHHHH
YKKPLIIIDFGTATTFCAVTKEANYLGGTICPGIKISSDALFDKAAKLPRVELVKTPGVI
HHCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCEECCHHHHHHHHCCCCEEEECCCCCH
CKNTVASIQSGIIYGYAGQVDYIVSKMKKEMMDLGEEEPFVVATGGFAKLISEESKSIDE
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCHHH
INAILTLEGLRVIYEKNK
HHHEEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA