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The map label for this gene is cysS [H]

Identifier: 226950955

GI number: 226950955

Start: 3996540

End: 3997937

Strand: Reverse

Name: cysS [H]

Synonym: CLM_3972

Alternate gene names: 226950955

Gene position: 3997937-3996540 (Counterclockwise)

Preceding gene: 226950956

Following gene: 226950954

Centisome position: 96.21

GC content: 28.25

Gene sequence:

>1398_bases
ATGAAGGTTTACAATACTTTAACTAATAAAAAAGAAGAGTTTCTTACGTTAGTACCAGGAGAAGTTAAAATGTATGTTTG
TGGTCCTACGGTATATAATTTTTTCCATATAGGGAATGCTAGAACTTTTGTAGTTTTTGATACTATAAGAAGGTATTTAG
AATATAGGGGTTATAAAGTGAAATTTATTCAAAATTTTACTGACATAGATGATAAGATGATAAAAAGAGCTAATGAAGAA
GGATCGACGGTAAAAGAATTAGGAGATAGGTTTATAAAAGAATATTATAAAGATGCAGATGACTTAAATATTGAAAGGGC
AACTAAAAATCCAAGAGCAACTGAATTCATGGAGGAAATAATAAAATTTGTGAGTGACCTAATAGAAAAAGGGTATGCTT
ATGAAATAGATGGTGACGTATATTTTAGTACTAAAAAATTTAATAGTTATGGTAAATTATCAGGACAAAATTTAGAAGAA
TTACAATTAGGAGCAAGAATAAATGTAGATGAAAGAAAAAAAGATCCTATGGACTTCGCTATATGGAAAAGCCAAAAGCC
GGGAGAACCTGCTTGGGAAAGTCCTTGGGGAATGGGAAGACCAGGTTGGCATATAGAATGCTCATGCATGGCTTATAATT
TGTTAGGAGAGACAATAGATATACATGCAGGAGGATCAGATTTATCATTCCCACATCATGAAAATGAAATAGCTCAAAGT
GAAGCAAGAACAGGAAAGCAATTTGCAAAGTATTGGTTACATTCAGCTTTTGTTAATGTAAATAATCAAAAAATGTCTAA
ATCATTAAATAATTTCTTTACAGCAAGAGAAATATTAGAAAAATATGATGCAGATGTTTTAAGAATGTTTATGTTATCAG
GACATTATAGAACTCAAATAAACTTTAGTATGGAGTTATTAGATTCAACTAAATCAGCTTTAGATAGATTGTATAATTCT
ATAAATAATTTAGAAAATTTATTAGATGAAGTAAAGAATGAAGAATTAAGAGATGAAGAATTAGAATATAAAAATGAATT
ACAAAAATATAAAGAAAAATATATAGAAAAAATGGATGATGATTTTAATACAGCAGATGCTATATCTGTAATATTTGATT
TAATAAGAGATGTTAATACAAATGTTACTATAGAATCATCAAAAGAACTAGTTAAATATACATTAGATTTAATAAGAGAA
TTAGGAAGCCCTTTAGGAATATTACAGGAATCAACTAAAGCTAGTTTAGAAGAAGAGATTGAAAAACTTATAGAAGAAAG
ACAAAAAGCTAGAAAAGAAAAAAATTGGGCATTAGCAGATAAAATTAGAGATAATTTGAAGGAAAGAGGCATTGTTTTGG
AAGATACACCACAGGGAGTAAGATGGAAGCAAATATAA

Upstream 100 bases:

>100_bases
GAACAAGGAGATAAATTATTGAAACAACTTAGCGAAAAAGGGTATAATATACAAACAAATATATGTATGTAATAAATTTA
GTAAAATAGGAGGTAAATAG

Downstream 100 bases:

>100_bases
GATATAAGTACTAGTGGATTAATAAAAATAGAATGAGTGGAGAGTAATATGGATTTTAGTTTATTTCAAAATAAGTTTAC
TATTAAGGATGGGAAAACAT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MKVYNTLTNKKEEFLTLVPGEVKMYVCGPTVYNFFHIGNARTFVVFDTIRRYLEYRGYKVKFIQNFTDIDDKMIKRANEE
GSTVKELGDRFIKEYYKDADDLNIERATKNPRATEFMEEIIKFVSDLIEKGYAYEIDGDVYFSTKKFNSYGKLSGQNLEE
LQLGARINVDERKKDPMDFAIWKSQKPGEPAWESPWGMGRPGWHIECSCMAYNLLGETIDIHAGGSDLSFPHHENEIAQS
EARTGKQFAKYWLHSAFVNVNNQKMSKSLNNFFTAREILEKYDADVLRMFMLSGHYRTQINFSMELLDSTKSALDRLYNS
INNLENLLDEVKNEELRDEELEYKNELQKYKEKYIEKMDDDFNTADAISVIFDLIRDVNTNVTIESSKELVKYTLDLIRE
LGSPLGILQESTKASLEEEIEKLIEERQKARKEKNWALADKIRDNLKERGIVLEDTPQGVRWKQI

Sequences:

>Translated_465_residues
MKVYNTLTNKKEEFLTLVPGEVKMYVCGPTVYNFFHIGNARTFVVFDTIRRYLEYRGYKVKFIQNFTDIDDKMIKRANEE
GSTVKELGDRFIKEYYKDADDLNIERATKNPRATEFMEEIIKFVSDLIEKGYAYEIDGDVYFSTKKFNSYGKLSGQNLEE
LQLGARINVDERKKDPMDFAIWKSQKPGEPAWESPWGMGRPGWHIECSCMAYNLLGETIDIHAGGSDLSFPHHENEIAQS
EARTGKQFAKYWLHSAFVNVNNQKMSKSLNNFFTAREILEKYDADVLRMFMLSGHYRTQINFSMELLDSTKSALDRLYNS
INNLENLLDEVKNEELRDEELEYKNELQKYKEKYIEKMDDDFNTADAISVIFDLIRDVNTNVTIESSKELVKYTLDLIRE
LGSPLGILQESTKASLEEEIEKLIEERQKARKEKNWALADKIRDNLKERGIVLEDTPQGVRWKQI
>Mature_465_residues
MKVYNTLTNKKEEFLTLVPGEVKMYVCGPTVYNFFHIGNARTFVVFDTIRRYLEYRGYKVKFIQNFTDIDDKMIKRANEE
GSTVKELGDRFIKEYYKDADDLNIERATKNPRATEFMEEIIKFVSDLIEKGYAYEIDGDVYFSTKKFNSYGKLSGQNLEE
LQLGARINVDERKKDPMDFAIWKSQKPGEPAWESPWGMGRPGWHIECSCMAYNLLGETIDIHAGGSDLSFPHHENEIAQS
EARTGKQFAKYWLHSAFVNVNNQKMSKSLNNFFTAREILEKYDADVLRMFMLSGHYRTQINFSMELLDSTKSALDRLYNS
INNLENLLDEVKNEELRDEELEYKNELQKYKEKYIEKMDDDFNTADAISVIFDLIRDVNTNVTIESSKELVKYTLDLIRE
LGSPLGILQESTKASLEEEIEKLIEERQKARKEKNWALADKIRDNLKERGIVLEDTPQGVRWKQI

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=480, Percent_Identity=33.9583333333333, Blast_Score=254, Evalue=9e-68,
Organism=Homo sapiens, GI21269877, Length=412, Percent_Identity=32.0388349514563, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI303304987, Length=412, Percent_Identity=32.0388349514563, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI10835051, Length=412, Percent_Identity=32.0388349514563, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI62240992, Length=412, Percent_Identity=32.0388349514563, Blast_Score=199, Evalue=4e-51,
Organism=Escherichia coli, GI1786737, Length=477, Percent_Identity=48.4276729559748, Blast_Score=449, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17509795, Length=358, Percent_Identity=35.195530726257, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17509797, Length=358, Percent_Identity=35.195530726257, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6324082, Length=361, Percent_Identity=37.3961218836565, Blast_Score=218, Evalue=2e-57,
Organism=Drosophila melanogaster, GI19922218, Length=500, Percent_Identity=34.2, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI19922364, Length=344, Percent_Identity=34.593023255814, Blast_Score=187, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 54304; Mature: 54304

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYNTLTNKKEEFLTLVPGEVKMYVCGPTVYNFFHIGNARTFVVFDTIRRYLEYRGYKV
CCCCHHHCCCHHHHEEECCCCEEEEEECCHHHHHEEECCCCEEEEHHHHHHHHHHCCCEE
KFIQNFTDIDDKMIKRANEEGSTVKELGDRFIKEYYKDADDLNIERATKNPRATEFMEEI
EEECCHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
IKFVSDLIEKGYAYEIDGDVYFSTKKFNSYGKLSGQNLEELQLGARINVDERKKDPMDFA
HHHHHHHHHCCCEEEECCCEEEEEHHCCCCCCCCCCCHHHHHCCCCCCCHHCCCCCCCEE
IWKSQKPGEPAWESPWGMGRPGWHIECSCMAYNLLGETIDIHAGGSDLSFPHHENEIAQS
EECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHH
EARTGKQFAKYWLHSAFVNVNNQKMSKSLNNFFTAREILEKYDADVLRMFMLSGHYRTQI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
NFSMELLDSTKSALDRLYNSINNLENLLDEVKNEELRDEELEYKNELQKYKEKYIEKMDD
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DFNTADAISVIFDLIRDVNTNVTIESSKELVKYTLDLIRELGSPLGILQESTKASLEEEI
CCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EKLIEERQKARKEKNWALADKIRDNLKERGIVLEDTPQGVRWKQI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MKVYNTLTNKKEEFLTLVPGEVKMYVCGPTVYNFFHIGNARTFVVFDTIRRYLEYRGYKV
CCCCHHHCCCHHHHEEECCCCEEEEEECCHHHHHEEECCCCEEEEHHHHHHHHHHCCCEE
KFIQNFTDIDDKMIKRANEEGSTVKELGDRFIKEYYKDADDLNIERATKNPRATEFMEEI
EEECCHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
IKFVSDLIEKGYAYEIDGDVYFSTKKFNSYGKLSGQNLEELQLGARINVDERKKDPMDFA
HHHHHHHHHCCCEEEECCCEEEEEHHCCCCCCCCCCCHHHHHCCCCCCCHHCCCCCCCEE
IWKSQKPGEPAWESPWGMGRPGWHIECSCMAYNLLGETIDIHAGGSDLSFPHHENEIAQS
EECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHH
EARTGKQFAKYWLHSAFVNVNNQKMSKSLNNFFTAREILEKYDADVLRMFMLSGHYRTQI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
NFSMELLDSTKSALDRLYNSINNLENLLDEVKNEELRDEELEYKNELQKYKEKYIEKMDD
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DFNTADAISVIFDLIRDVNTNVTIESSKELVKYTLDLIRELGSPLGILQESTKASLEEEI
CCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EKLIEERQKARKEKNWALADKIRDNLKERGIVLEDTPQGVRWKQI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA