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The map label for this gene is sigH [H]

Identifier: 226950950

GI number: 226950950

Start: 3993306

End: 3993947

Strand: Reverse

Name: sigH [H]

Synonym: CLM_3967

Alternate gene names: 226950950

Gene position: 3993947-3993306 (Counterclockwise)

Preceding gene: 226950951

Following gene: 226950949

Centisome position: 96.12

GC content: 30.22

Gene sequence:

>642_bases
TTGGATAGAAAGGTTCAAATTAATAGTAAAACTTCCTCCTTTGAAGGATGTGTAGATGAGGAAATAGTTATGGAAGCCAA
AGCAGGAAATTCTAGGGCACAAGAATATATAATCGGCAAATATGAGAATTTTGTTAAAGCTAAGGCAAAATCTTATTTTT
TAATAGGAGCAGATAAAGAAGATATATATCAAGAAGGTATGATAGGCTTATATAAAGCTATAAGAGATTTCAAACCAGAT
AAATTATCTTCCTTTAAAGCTTTTGCAGAACTTTGTGTTACTAGACAAATTATAACGGCTATAAAAACAGCAACTAGGCA
AAAACACATTCCGCTTAACACATACGTTTCTTTAAATAAGCCAATATATGATGAGGAGTCAGATAGAACCTTATTGGATA
TTTTATCAGAAGCTAAAGTGGCTAATCCAGAGGAATTAATTATAAGTAGAGAGGAACTAAAGCATATACAAAATGAGATA
GGCGAAGTATTATCAGATCTTGAAATGGAAGTTTTAATGTCTTATTTGGATGGAAAATCTTATCAAGAAATTGCCTGTGA
TTTAGATAGGCATGCTAAGTCTATAGATAATGCACTACAAAGAGTAAAAAGGAAATTAGAAAAATGTTTAAATAATAAAT
AA

Upstream 100 bases:

>100_bases
TTGGAAAAAATAAGAAGAAGCACATAATTTACCTTGACGTTGTTATTAACACTAATGTATAATCAAATATGTGGTTATAT
TTATTTTGGGGGGGGATACC

Downstream 100 bases:

>100_bases
TTTTACATATTGACAATAAAAACCGATTTTACTATAATTAATAATTGGTATATGATTATTTTGGGCGAGAGTAGTTCAGT
GGTAGAACACTAGCTTCCCA

Product: RNA polymerase factor sigma-70

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MDRKVQINSKTSSFEGCVDEEIVMEAKAGNSRAQEYIIGKYENFVKAKAKSYFLIGADKEDIYQEGMIGLYKAIRDFKPD
KLSSFKAFAELCVTRQIITAIKTATRQKHIPLNTYVSLNKPIYDEESDRTLLDILSEAKVANPEELIISREELKHIQNEI
GEVLSDLEMEVLMSYLDGKSYQEIACDLDRHAKSIDNALQRVKRKLEKCLNNK

Sequences:

>Translated_213_residues
MDRKVQINSKTSSFEGCVDEEIVMEAKAGNSRAQEYIIGKYENFVKAKAKSYFLIGADKEDIYQEGMIGLYKAIRDFKPD
KLSSFKAFAELCVTRQIITAIKTATRQKHIPLNTYVSLNKPIYDEESDRTLLDILSEAKVANPEELIISREELKHIQNEI
GEVLSDLEMEVLMSYLDGKSYQEIACDLDRHAKSIDNALQRVKRKLEKCLNNK
>Mature_213_residues
MDRKVQINSKTSSFEGCVDEEIVMEAKAGNSRAQEYIIGKYENFVKAKAKSYFLIGADKEDIYQEGMIGLYKAIRDFKPD
KLSSFKAFAELCVTRQIITAIKTATRQKHIPLNTYVSLNKPIYDEESDRTLLDILSEAKVANPEELIISREELKHIQNEI
GEVLSDLEMEVLMSYLDGKSYQEIACDLDRHAKSIDNALQRVKRKLEKCLNNK

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014218
- InterPro:   IPR016371
- InterPro:   IPR000943
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 24378; Mature: 24378

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00622 HTH_LUXR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRKVQINSKTSSFEGCVDEEIVMEAKAGNSRAQEYIIGKYENFVKAKAKSYFLIGADKE
CCCEEECCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCHH
DIYQEGMIGLYKAIRDFKPDKLSSFKAFAELCVTRQIITAIKTATRQKHIPLNTYVSLNK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCC
PIYDEESDRTLLDILSEAKVANPEELIISREELKHIQNEIGEVLSDLEMEVLMSYLDGKS
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YQEIACDLDRHAKSIDNALQRVKRKLEKCLNNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRKVQINSKTSSFEGCVDEEIVMEAKAGNSRAQEYIIGKYENFVKAKAKSYFLIGADKE
CCCEEECCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCHH
DIYQEGMIGLYKAIRDFKPDKLSSFKAFAELCVTRQIITAIKTATRQKHIPLNTYVSLNK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCC
PIYDEESDRTLLDILSEAKVANPEELIISREELKHIQNEIGEVLSDLEMEVLMSYLDGKS
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YQEIACDLDRHAKSIDNALQRVKRKLEKCLNNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3277943; 6322121 [H]