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The map label for this gene is srlA [H]

Identifier: 226950868

GI number: 226950868

Start: 3924934

End: 3925479

Strand: Reverse

Name: srlA [H]

Synonym: CLM_3882

Alternate gene names: 226950868

Gene position: 3925479-3924934 (Counterclockwise)

Preceding gene: 226950869

Following gene: 226950867

Centisome position: 94.47

GC content: 28.39

Gene sequence:

>546_bases
ATGGATTTTTTAACTAATTTAGCAAAAGGTTTTATAGGTTTATTTCAAGAAGGTGGAAATACTTTTGTAGGAATGGCAAA
AGGAATAATACCTACATTGATTATGCTTCTAGTTGCTATGAATGCTTTAATAAGAATAGTTGGAGAAGAAAGAATAGAAA
AGTTAGCTAAAAAAAGTGCAGCTAATCCAATAACTAGATATTTAATATTACCAGTAATAGGAACATTCTTTTTCTGCAAC
CCAATGACATTATCTTTAGGTAAATTTTTACCAGAAAAATATAAACCAAGTTATTATGCAGCGGCATCATATTCTTGTCA
TACAATGAATGGTTTATTTCCACACATAAATCCAGCAGAATTATTTGTATTCTTAGGTATAGCAAATGGTATAACACAAT
TAGGATTATCAACAACGGATTTAGCAGTTAGATATTTCTTAGTTGGTATAGTTACAAATTTCCTTAGAGGATGGATAACA
GATTTCACAACTTCTTATGTAGAAAAACAACAAAATGTAAAATTATCTACAAAAATTTCACTTTAG

Upstream 100 bases:

>100_bases
GATCAAAAATTATAATGAATATTATAAAACAAAGGAGGAGATTGATTCTAATTCATAATTGAGTCAATAAAAAACATTTT
ATTAAAAAGGAGATGAGTTT

Downstream 100 bases:

>100_bases
GAGGTGTAGTTGATGGCAAAATATAACGCAATAAAGGTTAGTGCAGGAAATGGCGGTTTTGGAGGCCCCCTTACAATAGT
TCCGACAGAGCAAAGAAATA

Product: PTS system glucitol/sorbitol-specific transporter subunit IIC

Products: D-sorbitol 6-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gut; PTS system glucitol/sorbitol-specific EIIC component [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MDFLTNLAKGFIGLFQEGGNTFVGMAKGIIPTLIMLLVAMNALIRIVGEERIEKLAKKSAANPITRYLILPVIGTFFFCN
PMTLSLGKFLPEKYKPSYYAAASYSCHTMNGLFPHINPAELFVFLGIANGITQLGLSTTDLAVRYFLVGIVTNFLRGWIT
DFTTSYVEKQQNVKLSTKISL

Sequences:

>Translated_181_residues
MDFLTNLAKGFIGLFQEGGNTFVGMAKGIIPTLIMLLVAMNALIRIVGEERIEKLAKKSAANPITRYLILPVIGTFFFCN
PMTLSLGKFLPEKYKPSYYAAASYSCHTMNGLFPHINPAELFVFLGIANGITQLGLSTTDLAVRYFLVGIVTNFLRGWIT
DFTTSYVEKQQNVKLSTKISL
>Mature_181_residues
MDFLTNLAKGFIGLFQEGGNTFVGMAKGIIPTLIMLLVAMNALIRIVGEERIEKLAKKSAANPITRYLILPVIGTFFFCN
PMTLSLGKFLPEKYKPSYYAAASYSCHTMNGLFPHINPAELFVFLGIANGITQLGLSTTDLAVRYFLVGIVTNFLRGWIT
DFTTSYVEKQQNVKLSTKISL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3730

COG function: function code G; Phosphotransferase system sorbitol-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994904, Length=181, Percent_Identity=64.0883977900553, Blast_Score=253, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004699 [H]

Pfam domain/function: PF03608 EII-GUT [H]

EC number: NA

Molecular weight: Translated: 20030; Mature: 20030

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS51107 PTS_EIIC_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLTNLAKGFIGLFQEGGNTFVGMAKGIIPTLIMLLVAMNALIRIVGEERIEKLAKKSA
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANPITRYLILPVIGTFFFCNPMTLSLGKFLPEKYKPSYYAAASYSCHTMNGLFPHINPAE
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHCCCCEEEECCCCHHHCCCCCCCCCHHH
LFVFLGIANGITQLGLSTTDLAVRYFLVGIVTNFLRGWITDFTTSYVEKQQNVKLSTKIS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
L
C
>Mature Secondary Structure
MDFLTNLAKGFIGLFQEGGNTFVGMAKGIIPTLIMLLVAMNALIRIVGEERIEKLAKKSA
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANPITRYLILPVIGTFFFCNPMTLSLGKFLPEKYKPSYYAAASYSCHTMNGLFPHINPAE
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHCCCCEEEECCCCHHHCCCCCCCCCHHH
LFVFLGIANGITQLGLSTTDLAVRYFLVGIVTNFLRGWITDFTTSYVEKQQNVKLSTKIS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; sorbitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + sorbitol [Periplasm] = D-sorbitol 6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9435786 [H]