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The map label for this gene is soxS [H]

Identifier: 226950811

GI number: 226950811

Start: 3864479

End: 3864886

Strand: Reverse

Name: soxS [H]

Synonym: CLM_3822

Alternate gene names: 226950811

Gene position: 3864886-3864479 (Counterclockwise)

Preceding gene: 226950812

Following gene: 226950810

Centisome position: 93.01

GC content: 33.82

Gene sequence:

>408_bases
ATGGATATGAAAGACCTCATATTAGAAATAATTGAACATATAGAATCTAATTTAGGTCAAGAAATGAATTTGGATACCAT
AGCAGATAAGTTTGGTTATTCAAAATTTCATTTGAATCGGATATTTTTTGAAAACGTGGGAGCTACGATTTACAAGTATA
TTCAATTTCGCAGACTATCTGTTGCAGCAGAAAAACTTGTAACGACTGGCAAACCCATCGTTGAGATTGCATATGACACA
GGTTATCAATCACAACAGGCCTTTTCAATTGCATTTCGGCAATTTTATGGTTATACCCCGCTGCAATATAGGCGTATAGG
AGTTTTCATACCCCTTTTAAAACGTTTTACAGCACAAAATATTATAATATCCCTATATGAAAATATCAACATGCCGTTTG
CTGCGTAA

Upstream 100 bases:

>100_bases
TGTGTTTTATTACTCAAAACGATAAAATAGCAATTTTCATTAAGACAAACATACAAGATTTGATTATAATGAAATGTAAA
CAATGAAAGGAGTGCGTGAT

Downstream 100 bases:

>100_bases
ACATTTTGATGTTAATAAAGCAAAAAAAGTAAAGTATAAGGGGTGATATGAAAATGAAAATAATGATAATAGGCGGTACT
AATTTTATCGGGCCGGTTGT

Product: AraC-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MDMKDLILEIIEHIESNLGQEMNLDTIADKFGYSKFHLNRIFFENVGATIYKYIQFRRLSVAAEKLVTTGKPIVEIAYDT
GYQSQQAFSIAFRQFYGYTPLQYRRIGVFIPLLKRFTAQNIIISLYENINMPFAA

Sequences:

>Translated_135_residues
MDMKDLILEIIEHIESNLGQEMNLDTIADKFGYSKFHLNRIFFENVGATIYKYIQFRRLSVAAEKLVTTGKPIVEIAYDT
GYQSQQAFSIAFRQFYGYTPLQYRRIGVFIPLLKRFTAQNIIISLYENINMPFAA
>Mature_135_residues
MDMKDLILEIIEHIESNLGQEMNLDTIADKFGYSKFHLNRIFFENVGATIYKYIQFRRLSVAAEKLVTTGKPIVEIAYDT
GYQSQQAFSIAFRQFYGYTPLQYRRIGVFIPLLKRFTAQNIIISLYENINMPFAA

Specific function: Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790497, Length=104, Percent_Identity=43.2692307692308, Blast_Score=87, Evalue=3e-19,
Organism=Escherichia coli, GI1790857, Length=124, Percent_Identity=40.3225806451613, Blast_Score=87, Evalue=5e-19,
Organism=Escherichia coli, GI87081928, Length=98, Percent_Identity=33.6734693877551, Blast_Score=77, Evalue=6e-16,

Paralogues:

None

Copy number: 2500 (L-broth) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 15720; Mature: 15720

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMKDLILEIIEHIESNLGQEMNLDTIADKFGYSKFHLNRIFFENVGATIYKYIQFRRLS
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAEKLVTTGKPIVEIAYDTGYQSQQAFSIAFRQFYGYTPLQYRRIGVFIPLLKRFTAQN
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IIISLYENINMPFAA
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MDMKDLILEIIEHIESNLGQEMNLDTIADKFGYSKFHLNRIFFENVGATIYKYIQFRRLS
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAEKLVTTGKPIVEIAYDTGYQSQQAFSIAFRQFYGYTPLQYRRIGVFIPLLKRFTAQN
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IIISLYENINMPFAA
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]