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The map label for this gene is trpS [H]

Identifier: 226950757

GI number: 226950757

Start: 3792240

End: 3793238

Strand: Reverse

Name: trpS [H]

Synonym: CLM_3767

Alternate gene names: 226950757

Gene position: 3793238-3792240 (Counterclockwise)

Preceding gene: 226950758

Following gene: 226950755

Centisome position: 91.29

GC content: 28.73

Gene sequence:

>999_bases
ATGGAAGATAATAAAAAGATTATATTTAGTGGAATTCAACCTTCCGGAAATTTAACTTTAGGTAATTATTTAGGTGCATT
AAAAAACTGGGTTAAGCTACAAGATGAATATGATTGTTACTATTGTGTAGTAGACTTACATGCTATAACAGTAAGACAAG
AACCTAAAGATTTAAGAAGAAGAACTTTAGAGGTATTAGCAATATATATAGCTTCAGGTATAGATCCTGATAAAAATACT
ATATTCATACAATCACATGTACCTACTCATTGTGAAGCTGGGTGGCTTTTAAACTGTAACACATATATAGGAGAATTATT
TAGAATGACTCAGTATAAAGATAAATCTCAACGTTATGGGGAATCAGTAAGTGCAGGGTTATTAACTTATCCAGTTTTAA
TGGCTGCGGATATATTATTATATAATACAGATTTGGTACCAGTAGGTAAAGATCAAAAACAACATTTAGAAATAACAAGA
GATTTAGCTCAAAGATTTAATAATTTATATAGTCCAACTTTTAAAATTCCAGAGCCATATATACCAGAAGCCGGAGCTAA
AATAATGGATCTTCAAGATCCAACTAAAAAAATGTCTAAGTCATCAGATAATGAGAATTCATATATATTAATTATGGATC
CACCAGATGCTATAAGAAGAAAAATTAATAGATGTGTAACAGATAGTTTAGGAATAGTTAAATATACAGATGAGCAGCCA
GGAATTAAAAATTTAATGACAATATTAAGTACAATAACTGGTATGACTATGGAAGAGATAGAAAAGAAATATGAAGGAAA
AGGATATGCTCAATTCAAAAATGATGTAGCAGAAGCTATAATTTCAGAATTGGAACCAATTCAAAACAAAGTGAATGAAT
TATTAACTAATAAAGAATACTTGGAATCTATATATAAAGAAGGAGCGGAAAAAGCTTATAAAGTATCCTATAAAATGCTA
AGAAAAATGCAAAAAAAGATAGGATTTATACCAAGATAG

Upstream 100 bases:

>100_bases
GTTTCTTGAATATAGGTGGTACCGCGATAATTCGCCCTATAACTTTTGTTGTAGGGTTTTTTTATATATTTTTTTTAATG
AAATAAATGGAGGTAGAGGT

Downstream 100 bases:

>100_bases
GATAAACAGAGTTCTTGGCTTTAGAGGGAGTTTTTACTCCCACTAAAGCTTATTAACAGAATTCTTAGGGGTTTTACTCC
TTAGAAGTCGTTATCCTTTA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MEDNKKIIFSGIQPSGNLTLGNYLGALKNWVKLQDEYDCYYCVVDLHAITVRQEPKDLRRRTLEVLAIYIASGIDPDKNT
IFIQSHVPTHCEAGWLLNCNTYIGELFRMTQYKDKSQRYGESVSAGLLTYPVLMAADILLYNTDLVPVGKDQKQHLEITR
DLAQRFNNLYSPTFKIPEPYIPEAGAKIMDLQDPTKKMSKSSDNENSYILIMDPPDAIRRKINRCVTDSLGIVKYTDEQP
GIKNLMTILSTITGMTMEEIEKKYEGKGYAQFKNDVAEAIISELEPIQNKVNELLTNKEYLESIYKEGAEKAYKVSYKML
RKMQKKIGFIPR

Sequences:

>Translated_332_residues
MEDNKKIIFSGIQPSGNLTLGNYLGALKNWVKLQDEYDCYYCVVDLHAITVRQEPKDLRRRTLEVLAIYIASGIDPDKNT
IFIQSHVPTHCEAGWLLNCNTYIGELFRMTQYKDKSQRYGESVSAGLLTYPVLMAADILLYNTDLVPVGKDQKQHLEITR
DLAQRFNNLYSPTFKIPEPYIPEAGAKIMDLQDPTKKMSKSSDNENSYILIMDPPDAIRRKINRCVTDSLGIVKYTDEQP
GIKNLMTILSTITGMTMEEIEKKYEGKGYAQFKNDVAEAIISELEPIQNKVNELLTNKEYLESIYKEGAEKAYKVSYKML
RKMQKKIGFIPR
>Mature_332_residues
MEDNKKIIFSGIQPSGNLTLGNYLGALKNWVKLQDEYDCYYCVVDLHAITVRQEPKDLRRRTLEVLAIYIASGIDPDKNT
IFIQSHVPTHCEAGWLLNCNTYIGELFRMTQYKDKSQRYGESVSAGLLTYPVLMAADILLYNTDLVPVGKDQKQHLEITR
DLAQRFNNLYSPTFKIPEPYIPEAGAKIMDLQDPTKKMSKSSDNENSYILIMDPPDAIRRKINRCVTDSLGIVKYTDEQP
GIKNLMTILSTITGMTMEEIEKKYEGKGYAQFKNDVAEAIISELEPIQNKVNELLTNKEYLESIYKEGAEKAYKVSYKML
RKMQKKIGFIPR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=41.3897280966767, Blast_Score=280, Evalue=2e-75,
Organism=Homo sapiens, GI41352700, Length=178, Percent_Identity=51.123595505618, Blast_Score=193, Evalue=2e-49,
Organism=Escherichia coli, GI1789786, Length=331, Percent_Identity=54.0785498489426, Blast_Score=396, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI71982800, Length=332, Percent_Identity=36.7469879518072, Blast_Score=203, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI71982793, Length=332, Percent_Identity=36.7469879518072, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6320474, Length=344, Percent_Identity=39.8255813953488, Blast_Score=227, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24666151, Length=325, Percent_Identity=38.4615384615385, Blast_Score=242, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38024; Mature: 38024

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDNKKIIFSGIQPSGNLTLGNYLGALKNWVKLQDEYDCYYCVVDLHAITVRQEPKDLRR
CCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEEEEEHEEECCCHHHHHH
RTLEVLAIYIASGIDPDKNTIFIQSHVPTHCEAGWLLNCNTYIGELFRMTQYKDKSQRYG
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHC
ESVSAGLLTYPVLMAADILLYNTDLVPVGKDQKQHLEITRDLAQRFNNLYSPTFKIPEPY
CHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
IPEAGAKIMDLQDPTKKMSKSSDNENSYILIMDPPDAIRRKINRCVTDSLGIVKYTDEQP
CCCCCCEEECCCCHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCC
GIKNLMTILSTITGMTMEEIEKKYEGKGYAQFKNDVAEAIISELEPIQNKVNELLTNKEY
CHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LESIYKEGAEKAYKVSYKMLRKMQKKIGFIPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEDNKKIIFSGIQPSGNLTLGNYLGALKNWVKLQDEYDCYYCVVDLHAITVRQEPKDLRR
CCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEEEEEHEEECCCHHHHHH
RTLEVLAIYIASGIDPDKNTIFIQSHVPTHCEAGWLLNCNTYIGELFRMTQYKDKSQRYG
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHC
ESVSAGLLTYPVLMAADILLYNTDLVPVGKDQKQHLEITRDLAQRFNNLYSPTFKIPEPY
CHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
IPEAGAKIMDLQDPTKKMSKSSDNENSYILIMDPPDAIRRKINRCVTDSLGIVKYTDEQP
CCCCCCEEECCCCHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCC
GIKNLMTILSTITGMTMEEIEKKYEGKGYAQFKNDVAEAIISELEPIQNKVNELLTNKEY
CHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LESIYKEGAEKAYKVSYKMLRKMQKKIGFIPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]