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The map label for this gene is etfA [H]

Identifier: 226950711

GI number: 226950711

Start: 3734199

End: 3735395

Strand: Reverse

Name: etfA [H]

Synonym: CLM_3719

Alternate gene names: 226950711

Gene position: 3735395-3734199 (Counterclockwise)

Preceding gene: 226950712

Following gene: 226950710

Centisome position: 89.9

GC content: 32.66

Gene sequence:

>1197_bases
ATGGCTATCAAAATTATTAAAGAAAAATGTAAAGCATGTGGTATATGTGAAAAGCAATGCCCATTTGATGCTATTCATGT
AGTTAACGGATTAGCAGAAGTAAATGAAAAATGTACAATATGTGGAGCCTGCGTAGAAGCTTGCCCATTTGATGCAATAG
AAAAAGAAGAGAAGAAAGTTGTAAAAAAGGATATTAGTAAATATAAAGGTGTATGGGTATACGCTGAACAAAGACAAGGA
GAACTTACTCCAGTAGTAATAGAATTATTAGGAGAAGGTAAAAAATTAGCTAATGAAATAGGAACAGATTTATCTGCAAT
TTTATTAGGAGATAATGTAGGATCACTAGCAGAAGAATTAATAAAGTATGGAGCAAATAAAGTATATGTAGCGGATGATA
AAAAATTAGAAAATTATACAACAGATGCTTATACTACAGTGATTTCAAATGCTATAGATCAATATAAGCCAGAATCAGTT
TTATTTGGTGCAACTCATATTGGAAGAGACTTAGCGCCTAGAATTGCAGCAAGAGTTGATACTGGACTTACAGCTGATTG
TACAAAGTTAGAGATAGATCCTGAAGCGAAAAACGTAAAACAAACTAGACCTGCATTTGGTGGAAACTTAATGGCAACTA
TAGTATGTAAGAACCATAGACCACAAATGTCTACAGTAAGACCTGGTGTTATGGAGAAAGCAAAATACAATGAAGACAAT
AAAGGTGAAATAATAGATATGAAAGTAGCATTAAGTGAAGATGAGATTAGAACTAAAGTTTTAGAGATAATTAAGTCTTC
TAAAAAACAAGTTTCTTTAGTTGATGCAGACTTTATCGTATCTGGTGGTAAGGGACTTGGAAATCCAGATGGATTTAAGT
TATTAAAAGAGTTAGCTGATTTATTAGGTGGAGTAGTTGGTAGTAGCCGTGCTGCAGTTGATATAGGATGGATAGAACAT
TCACATCAAGTTGGACAAACTGGAACAACTGTAAAACCTGTTATTTATATTGCATGTGGTATATCAGGAGCTATCCAGCA
CGTTGCTGGTATGTCAAATTCTGATATAATAATTGCTATAAATAAAGATGAAAATGCACCTATATTTGAAATAGCTGATT
ACGGAATTGTTGGAGACTTATATGAAATAGTTCCAATGCTAATAGAAGAAGTGAAAAAAATTAAACAAGAAGGCTAA

Upstream 100 bases:

>100_bases
CACAAGGTGTTATATTAGAAGGAACAGCTAAAGAAAAGGTAGAAAAATTAGTATCAGCACTTCAATCTAAACACTATATT
TAAGTTTTGGGAGGTTTATT

Downstream 100 bases:

>100_bases
GAAGGTTAATTAATTTACTTGCAAGAAACAAAATGAGGTTTTCCTCCTTTTGTTTCTTGTATATATTTTCAATAAATAGT
TAAAAAAATAACAATGAGGT

Product: electron transfer flavoprotein subunit alpha/FixB family protein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAIKIIKEKCKACGICEKQCPFDAIHVVNGLAEVNEKCTICGACVEACPFDAIEKEEKKVVKKDISKYKGVWVYAEQRQG
ELTPVVIELLGEGKKLANEIGTDLSAILLGDNVGSLAEELIKYGANKVYVADDKKLENYTTDAYTTVISNAIDQYKPESV
LFGATHIGRDLAPRIAARVDTGLTADCTKLEIDPEAKNVKQTRPAFGGNLMATIVCKNHRPQMSTVRPGVMEKAKYNEDN
KGEIIDMKVALSEDEIRTKVLEIIKSSKKQVSLVDADFIVSGGKGLGNPDGFKLLKELADLLGGVVGSSRAAVDIGWIEH
SHQVGQTGTTVKPVIYIACGISGAIQHVAGMSNSDIIIAINKDENAPIFEIADYGIVGDLYEIVPMLIEEVKKIKQEG

Sequences:

>Translated_398_residues
MAIKIIKEKCKACGICEKQCPFDAIHVVNGLAEVNEKCTICGACVEACPFDAIEKEEKKVVKKDISKYKGVWVYAEQRQG
ELTPVVIELLGEGKKLANEIGTDLSAILLGDNVGSLAEELIKYGANKVYVADDKKLENYTTDAYTTVISNAIDQYKPESV
LFGATHIGRDLAPRIAARVDTGLTADCTKLEIDPEAKNVKQTRPAFGGNLMATIVCKNHRPQMSTVRPGVMEKAKYNEDN
KGEIIDMKVALSEDEIRTKVLEIIKSSKKQVSLVDADFIVSGGKGLGNPDGFKLLKELADLLGGVVGSSRAAVDIGWIEH
SHQVGQTGTTVKPVIYIACGISGAIQHVAGMSNSDIIIAINKDENAPIFEIADYGIVGDLYEIVPMLIEEVKKIKQEG
>Mature_397_residues
AIKIIKEKCKACGICEKQCPFDAIHVVNGLAEVNEKCTICGACVEACPFDAIEKEEKKVVKKDISKYKGVWVYAEQRQGE
LTPVVIELLGEGKKLANEIGTDLSAILLGDNVGSLAEELIKYGANKVYVADDKKLENYTTDAYTTVISNAIDQYKPESVL
FGATHIGRDLAPRIAARVDTGLTADCTKLEIDPEAKNVKQTRPAFGGNLMATIVCKNHRPQMSTVRPGVMEKAKYNEDNK
GEIIDMKVALSEDEIRTKVLEIIKSSKKQVSLVDADFIVSGGKGLGNPDGFKLLKELADLLGGVVGSSRAAVDIGWIEHS
HQVGQTGTTVKPVIYIACGISGAIQHVAGMSNSDIIIAINKDENAPIFEIADYGIVGDLYEIVPMLIEEVKKIKQEG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=334, Percent_Identity=34.4311377245509, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI189181759, Length=286, Percent_Identity=37.0629370629371, Blast_Score=166, Evalue=4e-41,
Organism=Escherichia coli, GI1787990, Length=332, Percent_Identity=30.421686746988, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786226, Length=333, Percent_Identity=30.6306306306306, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87082157, Length=248, Percent_Identity=26.6129032258064, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=329, Percent_Identity=37.3860182370821, Blast_Score=192, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6325261, Length=311, Percent_Identity=31.5112540192926, Blast_Score=155, Evalue=8e-39,
Organism=Drosophila melanogaster, GI17136898, Length=335, Percent_Identity=36.4179104477612, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24652801, Length=335, Percent_Identity=36.4179104477612, Blast_Score=190, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 43096; Mature: 42965

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00198 4FE4S_FERREDOXIN ; PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKIIKEKCKACGICEKQCPFDAIHVVNGLAEVNEKCTICGACVEACPFDAIEKEEKKV
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
VKKDISKYKGVWVYAEQRQGELTPVVIELLGEGKKLANEIGTDLSAILLGDNVGSLAEEL
HHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHH
IKYGANKVYVADDKKLENYTTDAYTTVISNAIDQYKPESVLFGATHIGRDLAPRIAARVD
HHHCCCEEEEECCCHHCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHCHHHHHHHHHHHC
TGLTADCTKLEIDPEAKNVKQTRPAFGGNLMATIVCKNHRPQMSTVRPGVMEKAKYNEDN
CCCCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCHHHHHCCCCCC
KGEIIDMKVALSEDEIRTKVLEIIKSSKKQVSLVDADFIVSGGKGLGNPDGFKLLKELAD
CCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCHHHHHHHHHHH
LLGGVVGSSRAAVDIGWIEHSHQVGQTGTTVKPVIYIACGISGAIQHVAGMSNSDIIIAI
HHHHHHCCCCCEEEEEEHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEE
NKDENAPIFEIADYGIVGDLYEIVPMLIEEVKKIKQEG
ECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIKIIKEKCKACGICEKQCPFDAIHVVNGLAEVNEKCTICGACVEACPFDAIEKEEKKV
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
VKKDISKYKGVWVYAEQRQGELTPVVIELLGEGKKLANEIGTDLSAILLGDNVGSLAEEL
HHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHH
IKYGANKVYVADDKKLENYTTDAYTTVISNAIDQYKPESVLFGATHIGRDLAPRIAARVD
HHHCCCEEEEECCCHHCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHCHHHHHHHHHHHC
TGLTADCTKLEIDPEAKNVKQTRPAFGGNLMATIVCKNHRPQMSTVRPGVMEKAKYNEDN
CCCCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCHHHHHCCCCCC
KGEIIDMKVALSEDEIRTKVLEIIKSSKKQVSLVDADFIVSGGKGLGNPDGFKLLKELAD
CCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCHHHHHHHHHHH
LLGGVVGSSRAAVDIGWIEHSHQVGQTGTTVKPVIYIACGISGAIQHVAGMSNSDIIIAI
HHHHHHCCCCCEEEEEEHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEE
NKDENAPIFEIADYGIVGDLYEIVPMLIEEVKKIKQEG
ECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA