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The map label for this gene is sstT [H]

Identifier: 226950694

GI number: 226950694

Start: 3714573

End: 3715784

Strand: Reverse

Name: sstT [H]

Synonym: CLM_3702

Alternate gene names: 226950694

Gene position: 3715784-3714573 (Counterclockwise)

Preceding gene: 226950695

Following gene: 226950693

Centisome position: 89.42

GC content: 30.61

Gene sequence:

>1212_bases
ATGAAAAATTTAGGTCTTCTAACTAAATTAGTTTTAGGCATTATATTTGGTATTTTAATAGGGGTGATATCTAAGACCTT
AGACATGTATCATATTGTTAGGGCTTTAAATACATTTTCAGGATTATTTGGAGGATTTCTTAATTTCTGTATACCATTAA
TTATAGTAGGTTTTGTAGCACCTGGGATTGCAGATTTAGGAAAGGGATCAGGAAAATTATTAGGAATTACTGTATTATTT
GCTTATTTATCTACTATAATAGCAGGAATAGCTGCTTTCTTATTAGGTCAATCTATACTTCCGAGATTAATTAAGAATAG
TGGTAACATGTTTAAATCAAAGGTATATTTAGAACCATTTTTTAAAGTAGATATACCACCTATCATGGGAGTAATGTCAG
CTTTAGTATTTGCTTTTGTCTTAGGAATCTGTATTCCTTATATAAAAGGCAAGAATCTCTTAGAAGTTACAAAGGATTTT
AAAGGTATAGTTGAAATAATAGTTAAAAATGTAATAATACCATTAGTTCCCATTCATATAGCAGGTATATTTTCAAAACT
AACAGCTTCTGGGGAAATAGTCCAAACATTAAAGACATTTTCATCAGTATATTTGATAATAATACCGCTTCAAATAGCTT
ATATAGTATTACAATATTTTGTAGCTTATGCTGTTTCAAGAAAAAGTCCAATTAAAGCCATAAAAAACATGATACCAGGA
TATATGATGGCTTTAGGAACTCAATCTTCAGCAGCATCTATACCTGTAAATTTACAATGTGCTAAGAAAAATGATTTATC
GGATGATGTAGTTGATTTTGTAATACCTTTATGTGCTACAATACATTTAGCAGGAGATACTATAACTTTAGTATTAGGAG
CTATGGGTATAATGCTTATGTCAGGTCAAACGCCAACAGCGCCTTTAATGATACCATATATATTTATGTTAGGGGTTACT
ATGGTAGCAGCACCAGGAATACCTGGCGGTGGGGTATATGCTACTTTAGGGTTATTAAAAGATATGCTTATGTTTAATCC
GGCACAGCAAGGATTAATGATAGCTATACATTTTGCACAAGATAGTTTTGGAACAGCTACAAATGTTTGTGGAGATGGAG
CTATAGCTATAGTTGTAGATAAGTTATTCAGAAAAAAAAGTATTTCTGAAGAAAAAATGATTAAAGAAGAAGTATTTGGA
GAAGTTATATAA

Upstream 100 bases:

>100_bases
ATATTGACAAATATAAAGCCAGATGTTATCATAAATTTGCGTTTTAATCAAAAACATATGTATATAGTATAAATACATGT
GAACTAAGGGGGAGAGTAAA

Downstream 100 bases:

>100_bases
TATAATAAAAAACTGCCTGATTTTTACAGGCAGTTTTTTTATTTCTATGTAAAAAATATATATTTGTGGTAAAATAAAAA
TATTAGCCTTCATAAGGTAA

Product: sodium:dicarboxylate symporter family protein

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MKNLGLLTKLVLGIIFGILIGVISKTLDMYHIVRALNTFSGLFGGFLNFCIPLIIVGFVAPGIADLGKGSGKLLGITVLF
AYLSTIIAGIAAFLLGQSILPRLIKNSGNMFKSKVYLEPFFKVDIPPIMGVMSALVFAFVLGICIPYIKGKNLLEVTKDF
KGIVEIIVKNVIIPLVPIHIAGIFSKLTASGEIVQTLKTFSSVYLIIIPLQIAYIVLQYFVAYAVSRKSPIKAIKNMIPG
YMMALGTQSSAASIPVNLQCAKKNDLSDDVVDFVIPLCATIHLAGDTITLVLGAMGIMLMSGQTPTAPLMIPYIFMLGVT
MVAAPGIPGGGVYATLGLLKDMLMFNPAQQGLMIAIHFAQDSFGTATNVCGDGAIAIVVDKLFRKKSISEEKMIKEEVFG
EVI

Sequences:

>Translated_403_residues
MKNLGLLTKLVLGIIFGILIGVISKTLDMYHIVRALNTFSGLFGGFLNFCIPLIIVGFVAPGIADLGKGSGKLLGITVLF
AYLSTIIAGIAAFLLGQSILPRLIKNSGNMFKSKVYLEPFFKVDIPPIMGVMSALVFAFVLGICIPYIKGKNLLEVTKDF
KGIVEIIVKNVIIPLVPIHIAGIFSKLTASGEIVQTLKTFSSVYLIIIPLQIAYIVLQYFVAYAVSRKSPIKAIKNMIPG
YMMALGTQSSAASIPVNLQCAKKNDLSDDVVDFVIPLCATIHLAGDTITLVLGAMGIMLMSGQTPTAPLMIPYIFMLGVT
MVAAPGIPGGGVYATLGLLKDMLMFNPAQQGLMIAIHFAQDSFGTATNVCGDGAIAIVVDKLFRKKSISEEKMIKEEVFG
EVI
>Mature_403_residues
MKNLGLLTKLVLGIIFGILIGVISKTLDMYHIVRALNTFSGLFGGFLNFCIPLIIVGFVAPGIADLGKGSGKLLGITVLF
AYLSTIIAGIAAFLLGQSILPRLIKNSGNMFKSKVYLEPFFKVDIPPIMGVMSALVFAFVLGICIPYIKGKNLLEVTKDF
KGIVEIIVKNVIIPLVPIHIAGIFSKLTASGEIVQTLKTFSSVYLIIIPLQIAYIVLQYFVAYAVSRKSPIKAIKNMIPG
YMMALGTQSSAASIPVNLQCAKKNDLSDDVVDFVIPLCATIHLAGDTITLVLGAMGIMLMSGQTPTAPLMIPYIFMLGVT
MVAAPGIPGGGVYATLGLLKDMLMFNPAQQGLMIAIHFAQDSFGTATNVCGDGAIAIVVDKLFRKKSISEEKMIKEEVFG
EVI

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI169790839, Length=271, Percent_Identity=28.7822878228782, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI66773030, Length=187, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI40254478, Length=189, Percent_Identity=27.5132275132275, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI223468564, Length=281, Percent_Identity=22.7758007117438, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI223468566, Length=178, Percent_Identity=25.8426966292135, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17537407, Length=426, Percent_Identity=24.8826291079812, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71996953, Length=270, Percent_Identity=25.1851851851852, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 43131; Mature: 43131

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLGLLTKLVLGIIFGILIGVISKTLDMYHIVRALNTFSGLFGGFLNFCIPLIIVGFVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PGIADLGKGSGKLLGITVLFAYLSTIIAGIAAFLLGQSILPRLIKNSGNMFKSKVYLEPF
CCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEECCH
FKVDIPPIMGVMSALVFAFVLGICIPYIKGKNLLEVTKDFKGIVEIIVKNVIIPLVPIHI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGIFSKLTASGEIVQTLKTFSSVYLIIIPLQIAYIVLQYFVAYAVSRKSPIKAIKNMIPG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCH
YMMALGTQSSAASIPVNLQCAKKNDLSDDVVDFVIPLCATIHLAGDTITLVLGAMGIMLM
HHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
SGQTPTAPLMIPYIFMLGVTMVAAPGIPGGGVYATLGLLKDMLMFNPAQQGLMIAIHFAQ
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
DSFGTATNVCGDGAIAIVVDKLFRKKSISEEKMIKEEVFGEVI
CCCCCHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure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CCCCCHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA