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The map label for this gene is yggV [C]

Identifier: 226950687

GI number: 226950687

Start: 3707128

End: 3707727

Strand: Reverse

Name: yggV [C]

Synonym: CLM_3695

Alternate gene names: 226950687

Gene position: 3707727-3707128 (Counterclockwise)

Preceding gene: 226950690

Following gene: 226950686

Centisome position: 89.23

GC content: 28.0

Gene sequence:

>600_bases
ATGAAAAAAGAAGTTATTGTTGCAAGTAATAACAAAGATAAAATAAGAGAAATAAAAGAAATATTAAAAAAATTTAATAT
AGATGCTTTATCGATGAAAGAAGCAGGTATTGATATAGATATAGAAGAAGATGGCAATACATTTATGGGAAATGCTTATA
AAAAAGCAGCTACTATATATGAAATTTTGCCTAACTATATGGTAATAGCAGATGATTCAGGGCTTATGGTAGATGCTTTA
AATGGAGCTCCAGGAATTTATTCTGCTAGATTTGCAGGGGAGCATGGAAATTATAAAAAAAATAATGAAAAGTTATTAAA
AGAACTGGATGGTAAAAAAGTAGAAGAGAGAAAAGCTAAATTTGTTTGCTCTATAGTATTTATAATAGATAAGGATAATG
TAATAAGAGTGCAAGGTGAAATTAATGGGGTTATAGGAGAAAAAGAAATAGGAGAGGATGGATTTGGATATGATCCTTTA
TTCTATATACCAGAGTATAAAAAAACCTTTGCACAAATGGATTCTCAAACTAAAAATTCTATAAGTCATAGGGGAGAAGC
CTTTAGAAAATTAAAATGCGAATTAGAAAAAAATATATAG

Upstream 100 bases:

>100_bases
ACACACCTACCATAAATTAATTCTTATATTATAATATGTTATACAAGGGCAATTTAGTGATACATAAATAAAATATTTAA
TTTGTTTGGAGGATTAACAT

Downstream 100 bases:

>100_bases
ATAAGGGGGGACAATTTTGAAAATAGGTGTTATTAGTGATACCCATAGATATATAGGAGATGCTACTTCTCTTGTAAATA
GTTTAGGTAATGTAAACTTA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MKKEVIVASNNKDKIREIKEILKKFNIDALSMKEAGIDIDIEEDGNTFMGNAYKKAATIYEILPNYMVIADDSGLMVDAL
NGAPGIYSARFAGEHGNYKKNNEKLLKELDGKKVEERKAKFVCSIVFIIDKDNVIRVQGEINGVIGEKEIGEDGFGYDPL
FYIPEYKKTFAQMDSQTKNSISHRGEAFRKLKCELEKNI

Sequences:

>Translated_199_residues
MKKEVIVASNNKDKIREIKEILKKFNIDALSMKEAGIDIDIEEDGNTFMGNAYKKAATIYEILPNYMVIADDSGLMVDAL
NGAPGIYSARFAGEHGNYKKNNEKLLKELDGKKVEERKAKFVCSIVFIIDKDNVIRVQGEINGVIGEKEIGEDGFGYDPL
FYIPEYKKTFAQMDSQTKNSISHRGEAFRKLKCELEKNI
>Mature_199_residues
MKKEVIVASNNKDKIREIKEILKKFNIDALSMKEAGIDIDIEEDGNTFMGNAYKKAATIYEILPNYMVIADDSGLMVDAL
NGAPGIYSARFAGEHGNYKKNNEKLLKELDGKKVEERKAKFVCSIVFIIDKDNVIRVQGEINGVIGEKEIGEDGFGYDPL
FYIPEYKKTFAQMDSQTKNSISHRGEAFRKLKCELEKNI

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=193, Percent_Identity=40.4145077720207, Blast_Score=146, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6322529, Length=199, Percent_Identity=27.1356783919598, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22484; Mature: 22484

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEVIVASNNKDKIREIKEILKKFNIDALSMKEAGIDIDIEEDGNTFMGNAYKKAATIY
CCCCEEEECCCHHHHHHHHHHHHHHCCCEEEHHCCCCEEEECCCCCEECCCHHHHHHHHH
EILPNYMVIADDSGLMVDALNGAPGIYSARFAGEHGNYKKNNEKLLKELDGKKVEERKAK
HHCCCEEEEECCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHH
FVCSIVFIIDKDNVIRVQGEINGVIGEKEIGEDGFGYDPLFYIPEYKKTFAQMDSQTKNS
EEEEEEEEECCCCEEEEEECCCCEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
ISHRGEAFRKLKCELEKNI
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKEVIVASNNKDKIREIKEILKKFNIDALSMKEAGIDIDIEEDGNTFMGNAYKKAATIY
CCCCEEEECCCHHHHHHHHHHHHHHCCCEEEHHCCCCEEEECCCCCEECCCHHHHHHHHH
EILPNYMVIADDSGLMVDALNGAPGIYSARFAGEHGNYKKNNEKLLKELDGKKVEERKAK
HHCCCEEEEECCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHH
FVCSIVFIIDKDNVIRVQGEINGVIGEKEIGEDGFGYDPLFYIPEYKKTFAQMDSQTKNS
EEEEEEEEECCCCEEEEEECCCCEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
ISHRGEAFRKLKCELEKNI
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]