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The map label for this gene is galE [H]

Identifier: 226950191

GI number: 226950191

Start: 3152672

End: 3153652

Strand: Reverse

Name: galE [H]

Synonym: CLM_3145

Alternate gene names: 226950191

Gene position: 3153652-3152672 (Counterclockwise)

Preceding gene: 226950192

Following gene: 226950190

Centisome position: 75.9

GC content: 32.01

Gene sequence:

>981_bases
TTGGCTATATTAGTATGTGGAGGAGCAGGATATATAGGAAGCCATGCGGTGGCAGCCTTAATTGAGAAAAATGAAGAAGT
AGTTATTGTAGATAATTTAGTTACAGGTCATGAACAAGCCATATGCGGTGGTAAATTTTATAAAGGCGACTTAAGAGATA
AAGAATTTTTAAATAAGGTTTTTAACCAAAATAAAATAGATGCAGTTATTCATTTTGCAGCTTTTTCTTTGGTTGGAGAA
AGTATGGAAGAACCTTTTAAATATTATAATAATAATGTATGTGGAACGTTAAGCTTATTAGAAACAATGAAAGAATATAA
TGTACAGAAAATAGTATTTTCATCTACAGCAGCAACTTATGGAGAACCAGAAAATATACCAATATTAGAAGAAGATCTTA
CAGAGCCTACGAATGCTTATGGAGAAACTAAACTTGCAGTAGAAAAAATGCTTAAATGGGCAGAAATGGCTTATAATATA
AAATATGTTGTATTAAGATATTTTAATGTAGCAGGAGCTCACGAAAGCGGTAATATAGGAGAGGCACATAAGGTAGAAAG
TCATCTGATACCTATAATACTTCAAGTAGCATTAGGACGAAGAGAAAAAATAATGATATATGGAGATGATTATAATACTA
AAGATGGAAGTTGTGTAAGAGATTATATTCATGTAATGGATTTAGTAGAAGCTCATATTCTAGCACTAGAAAAATTAAGA
AGAGATAATACTAGTGATACATATAATTTAGGTAATGGAGAGGGATTTAGTGTTAAAGAAGTTATAGATATATGCAGGAA
AGTTACAGGGCATGCTATACCATCAGAAATAGCTGCAAGAAGATCAGGAGACCCAGCTATACTTATAGCATCATCTGAAA
AGATAATAAAAGAACTGGGTTGGAATCCTAAGAAAGCCTCTTTAGAAAGTATAATTGATAGTGCTTGGAAATGGCACAGA
TTCCATCCAGATGGATATTAG

Upstream 100 bases:

>100_bases
TAACTAATAAGTTACTTTTATTTAATAGAGTAATATTAAAATAATGTGTATAATTAATAATATGTACTTTATTGTTAAAT
TCAGATAGGAGTGATATTAG

Downstream 100 bases:

>100_bases
AATATTAAAGGAATACAAGGGAGTGTAGCTTGAAATTATGGAAGATAAATTTATAGATTTAAATTTAAAGTTTAATGAGG
AAATAGATAAAAAATCCATA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAILVCGGAGYIGSHAVAALIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKVFNQNKIDAVIHFAAFSLVGE
SMEEPFKYYNNNVCGTLSLLETMKEYNVQKIVFSSTAATYGEPENIPILEEDLTEPTNAYGETKLAVEKMLKWAEMAYNI
KYVVLRYFNVAGAHESGNIGEAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHILALEKLR
RDNTSDTYNLGNGEGFSVKEVIDICRKVTGHAIPSEIAARRSGDPAILIASSEKIIKELGWNPKKASLESIIDSAWKWHR
FHPDGY

Sequences:

>Translated_326_residues
MAILVCGGAGYIGSHAVAALIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKVFNQNKIDAVIHFAAFSLVGE
SMEEPFKYYNNNVCGTLSLLETMKEYNVQKIVFSSTAATYGEPENIPILEEDLTEPTNAYGETKLAVEKMLKWAEMAYNI
KYVVLRYFNVAGAHESGNIGEAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHILALEKLR
RDNTSDTYNLGNGEGFSVKEVIDICRKVTGHAIPSEIAARRSGDPAILIASSEKIIKELGWNPKKASLESIIDSAWKWHR
FHPDGY
>Mature_325_residues
AILVCGGAGYIGSHAVAALIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKVFNQNKIDAVIHFAAFSLVGES
MEEPFKYYNNNVCGTLSLLETMKEYNVQKIVFSSTAATYGEPENIPILEEDLTEPTNAYGETKLAVEKMLKWAEMAYNIK
YVVLRYFNVAGAHESGNIGEAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHILALEKLRR
DNTSDTYNLGNGEGFSVKEVIDICRKVTGHAIPSEIAARRSGDPAILIASSEKIIKELGWNPKKASLESIIDSAWKWHRF
HPDGY

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=346, Percent_Identity=40.1734104046243, Blast_Score=254, Evalue=5e-68,
Organism=Homo sapiens, GI56118217, Length=346, Percent_Identity=40.1734104046243, Blast_Score=254, Evalue=5e-68,
Organism=Homo sapiens, GI189083684, Length=346, Percent_Identity=40.1734104046243, Blast_Score=254, Evalue=5e-68,
Organism=Homo sapiens, GI7657641, Length=341, Percent_Identity=28.4457478005865, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI42516563, Length=326, Percent_Identity=27.6073619631902, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI193211614, Length=244, Percent_Identity=27.4590163934426, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI8393516, Length=244, Percent_Identity=27.4590163934426, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI116268111, Length=289, Percent_Identity=26.2975778546713, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=40.9495548961424, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1788353, Length=356, Percent_Identity=27.5280898876405, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994969, Length=349, Percent_Identity=26.0744985673352, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790049, Length=267, Percent_Identity=29.2134831460674, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788366, Length=347, Percent_Identity=23.0547550432277, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=39.9425287356322, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=39.7142857142857, Blast_Score=244, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17539532, Length=312, Percent_Identity=27.8846153846154, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17568069, Length=247, Percent_Identity=30.3643724696356, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=355, Percent_Identity=24.7887323943662, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=43.731778425656, Blast_Score=268, Evalue=6e-73,
Organism=Saccharomyces cerevisiae, GI6321437, Length=341, Percent_Identity=25.5131964809384, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19923002, Length=353, Percent_Identity=42.2096317280453, Blast_Score=257, Evalue=9e-69,
Organism=Drosophila melanogaster, GI21356223, Length=328, Percent_Identity=28.3536585365854, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36376; Mature: 36245

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVCGGAGYIGSHAVAALIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKV
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHEECCCCCCCCCCCHHHHHHH
FNQNKIDAVIHFAAFSLVGESMEEPFKYYNNNVCGTLSLLETMKEYNVQKIVFSSTAATY
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHEEEEECCCCCC
GEPENIPILEEDLTEPTNAYGETKLAVEKMLKWAEMAYNIKYVVLRYFNVAGAHESGNIG
CCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHILALEKLR
CHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDNTSDTYNLGNGEGFSVKEVIDICRKVTGHAIPSEIAARRSGDPAILIASSEKIIKELG
CCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCHHHHHHCC
WNPKKASLESIIDSAWKWHRFHPDGY
CCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AILVCGGAGYIGSHAVAALIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKV
EEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHEECCCCCCCCCCCHHHHHHH
FNQNKIDAVIHFAAFSLVGESMEEPFKYYNNNVCGTLSLLETMKEYNVQKIVFSSTAATY
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHEEEEECCCCCC
GEPENIPILEEDLTEPTNAYGETKLAVEKMLKWAEMAYNIKYVVLRYFNVAGAHESGNIG
CCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHILALEKLR
CHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDNTSDTYNLGNGEGFSVKEVIDICRKVTGHAIPSEIAARRSGDPAILIASSEKIIKELG
CCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCHHHHHHCC
WNPKKASLESIIDSAWKWHRFHPDGY
CCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]