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The map label for this gene is pqqL [C]

Identifier: 226950179

GI number: 226950179

Start: 3138858

End: 3140075

Strand: Reverse

Name: pqqL [C]

Synonym: CLM_3133

Alternate gene names: 226950179

Gene position: 3140075-3138858 (Counterclockwise)

Preceding gene: 226950182

Following gene: 226950178

Centisome position: 75.57

GC content: 24.47

Gene sequence:

>1218_bases
ATGGAGAAATTGAAATTAGAAAATGGAATAAGAGTAGTTTATAAAAAAACTTTAAGTAATATAAGTTCTATATCTATAGG
TTTTAATGCAGGAGCTTTAGAAGAAAAAGATGAGTTCCCTTTTGGTACAGCTCATGCTGTAGAGCACATGGTATCTAAGG
GAACTCTTAATAGAGGAGAGAAAGAAATAAATATTTTAGCAGATAGTATTTTTGGGTTTGAAAATGCCATGACTAATTAT
CCTTATGTAGTGTATTATGGAAGTTTTCTGAATGAAGATTTAGAAAAAGCATTAGATTTTTATAGTGATATATTATTAAA
TCCAAAGTTTGAAGAAAAAGCTTTCCAGGAAGAAAAATCTATTATATTAGAGGAATTGAAAGAATGGAGAGGGGATCCTT
ATCAATTTTGTGAGGATCAAATGCTAAAAAATTCTTTTAAAGAAAGAAGAATAAAAGAATTGATTATAGGGAATGAGGAA
AGTATTAAAAATATTACTTTAAATAATATAAAAGATTTTTATAATGCCTATTATACTCCTGAAAATTGTGTGATTACTAT
AGTAACATCAATGGGGATAGAAGAAAGTATAAAATGTATAAAAAAATTTTTTGAACATTTTAATAAACCGTATAGAGAAA
TAAAAGAAGTAAGATATGAAAATAGAAAAGAAACTATTTATACTGACTATAAAGATGGTATAGAAGGAGCTAAAATAATA
TATAGCTATGATATTCATAGTTTAAATAAAGAAGAAATAATGGCTCTTAAAATATTTAATGAAATATTTGCAGAAGGTAC
AAGTAGCATTTTGTTCCATAATATTAGAACCATAAATTCTTTAGCTTATGATGTAGGGAGTAATTTTAAAAATGAAAGAG
GTATAAAATTATTTGATTTTTATATAGGTACATCCAAAGAAAAAGTAAGTAAAGCTATTAATATAATGGATAAAATTCTA
GAAGGAATAATAGATAACAAAGAATATTTTACAAAAGAAAGGATATGCAGAGCCTTAAAAAGTATAAAACTTAAAAAAGC
TATACGTCATGAAATGTCTATAAGGCTAGCTTTAGATATTACCACTTCTGAACTTATGTATAATGATAGTTTAAATATAA
ATGGTTCTATAGAGGATTTAAGTTTAATAAAAGAAGAAAATATAAAAAAAGTATTGAAAAAGATTTTTAAAAGTAAAGTT
ATACAGATATTACAATAA

Upstream 100 bases:

>100_bases
TTAAAACTATTCAGTTAAGGTAGAGTTATAAAAAATGAACCCATCCCTAATTAAATTAAGAGAGGTGATAATATTTTAAT
CTTTGATTAAAATATAAATT

Downstream 100 bases:

>100_bases
TAATTAATTAATTTACTACATTCTTTATAAAGGGTGTAGTTTTTTTCATATTCTTTAAGATATTTTTATATATTATAATA
TCAAATTTAATAAGTAGTAT

Product: peptidase, M16 family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MEKLKLENGIRVVYKKTLSNISSISIGFNAGALEEKDEFPFGTAHAVEHMVSKGTLNRGEKEINILADSIFGFENAMTNY
PYVVYYGSFLNEDLEKALDFYSDILLNPKFEEKAFQEEKSIILEELKEWRGDPYQFCEDQMLKNSFKERRIKELIIGNEE
SIKNITLNNIKDFYNAYYTPENCVITIVTSMGIEESIKCIKKFFEHFNKPYREIKEVRYENRKETIYTDYKDGIEGAKII
YSYDIHSLNKEEIMALKIFNEIFAEGTSSILFHNIRTINSLAYDVGSNFKNERGIKLFDFYIGTSKEKVSKAINIMDKIL
EGIIDNKEYFTKERICRALKSIKLKKAIRHEMSIRLALDITTSELMYNDSLNINGSIEDLSLIKEENIKKVLKKIFKSKV
IQILQ

Sequences:

>Translated_405_residues
MEKLKLENGIRVVYKKTLSNISSISIGFNAGALEEKDEFPFGTAHAVEHMVSKGTLNRGEKEINILADSIFGFENAMTNY
PYVVYYGSFLNEDLEKALDFYSDILLNPKFEEKAFQEEKSIILEELKEWRGDPYQFCEDQMLKNSFKERRIKELIIGNEE
SIKNITLNNIKDFYNAYYTPENCVITIVTSMGIEESIKCIKKFFEHFNKPYREIKEVRYENRKETIYTDYKDGIEGAKII
YSYDIHSLNKEEIMALKIFNEIFAEGTSSILFHNIRTINSLAYDVGSNFKNERGIKLFDFYIGTSKEKVSKAINIMDKIL
EGIIDNKEYFTKERICRALKSIKLKKAIRHEMSIRLALDITTSELMYNDSLNINGSIEDLSLIKEENIKKVLKKIFKSKV
IQILQ
>Mature_405_residues
MEKLKLENGIRVVYKKTLSNISSISIGFNAGALEEKDEFPFGTAHAVEHMVSKGTLNRGEKEINILADSIFGFENAMTNY
PYVVYYGSFLNEDLEKALDFYSDILLNPKFEEKAFQEEKSIILEELKEWRGDPYQFCEDQMLKNSFKERRIKELIIGNEE
SIKNITLNNIKDFYNAYYTPENCVITIVTSMGIEESIKCIKKFFEHFNKPYREIKEVRYENRKETIYTDYKDGIEGAKII
YSYDIHSLNKEEIMALKIFNEIFAEGTSSILFHNIRTINSLAYDVGSNFKNERGIKLFDFYIGTSKEKVSKAINIMDKIL
EGIIDNKEYFTKERICRALKSIKLKKAIRHEMSIRLALDITTSELMYNDSLNINGSIEDLSLIKEENIKKVLKKIFKSKV
IQILQ

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=203, Percent_Identity=26.1083743842365, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI46593007, Length=190, Percent_Identity=21.5789473684211, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1787770, Length=431, Percent_Identity=21.8097447795824, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71999683, Length=407, Percent_Identity=22.1130221130221, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17553678, Length=266, Percent_Identity=24.0601503759398, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=207, Percent_Identity=29.951690821256, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357875, Length=194, Percent_Identity=25.2577319587629, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24646943, Length=194, Percent_Identity=25.2577319587629, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47152; Mature: 47152

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLKLENGIRVVYKKTLSNISSISIGFNAGALEEKDEFPFGTAHAVEHMVSKGTLNRGE
CCCCCCCCCHHHHHHHHHHCHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
KEINILADSIFGFENAMTNYPYVVYYGSFLNEDLEKALDFYSDILLNPKFEEKAFQEEKS
HHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IILEELKEWRGDPYQFCEDQMLKNSFKERRIKELIIGNEESIKNITLNNIKDFYNAYYTP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHCCCC
ENCVITIVTSMGIEESIKCIKKFFEHFNKPYREIKEVRYENRKETIYTDYKDGIEGAKII
CCCEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEECCHHCCCCCCEEE
YSYDIHSLNKEEIMALKIFNEIFAEGTSSILFHNIRTINSLAYDVGSNFKNERGIKLFDF
EEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
YIGTSKEKVSKAINIMDKILEGIIDNKEYFTKERICRALKSIKLKKAIRHEMSIRLALDI
EECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
TTSELMYNDSLNINGSIEDLSLIKEENIKKVLKKIFKSKVIQILQ
EHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKLKLENGIRVVYKKTLSNISSISIGFNAGALEEKDEFPFGTAHAVEHMVSKGTLNRGE
CCCCCCCCCHHHHHHHHHHCHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
KEINILADSIFGFENAMTNYPYVVYYGSFLNEDLEKALDFYSDILLNPKFEEKAFQEEKS
HHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IILEELKEWRGDPYQFCEDQMLKNSFKERRIKELIIGNEESIKNITLNNIKDFYNAYYTP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHCCCC
ENCVITIVTSMGIEESIKCIKKFFEHFNKPYREIKEVRYENRKETIYTDYKDGIEGAKII
CCCEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEECCHHCCCCCCEEE
YSYDIHSLNKEEIMALKIFNEIFAEGTSSILFHNIRTINSLAYDVGSNFKNERGIKLFDF
EEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
YIGTSKEKVSKAINIMDKILEGIIDNKEYFTKERICRALKSIKLKKAIRHEMSIRLALDI
EECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
TTSELMYNDSLNINGSIEDLSLIKEENIKKVLKKIFKSKVIQILQ
EHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]