| Definition | Clostridium botulinum A2 str. Kyoto chromosome, complete genome. |
|---|---|
| Accession | NC_012563 |
| Length | 4,155,278 |
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The map label for this gene is cheA [H]
Identifier: 226950160
GI number: 226950160
Start: 3111354
End: 3113429
Strand: Reverse
Name: cheA [H]
Synonym: CLM_3114
Alternate gene names: 226950160
Gene position: 3113429-3111354 (Counterclockwise)
Preceding gene: 226950161
Following gene: 226950159
Centisome position: 74.93
GC content: 29.87
Gene sequence:
>2076_bases ATGGATACATCACAATACATGTCAATGTTCCTAGAAGAATCTATGGACAATTTACAAACATTAAATGACTCCTTACTTCA ATTAGAACAAGAGCCAGATGATATAGATAAACTAAATGAAATATTTAGAGTTGCCCATACCATAAAAGGAATGGCAGCCA CTATGGGCTTTAATGAGATGTCAGAGTTGACTCATAAAATGGAAGACGTACTTTCTAATTTTAGAGAAGGAGATTTAAAA GTAACACAGAATGTAGTTACTGTACTTTTTAAATGTCTAGATACTCTAGAACAAATGGTAAATAATATATCAGAAGAGGT AGACGAAAAGGTTCCAATAGATCACATAATAGAAGAACTAGAGAAGGCAGCAAATGGAGATATAAGTTCACAAGAAAATG AAAAAGAGGCTATAGAAACTATAGAGGGAAATAAAAGTGAAGGAAATTCTACCATACCACTAAATGAATATGATTTAAAT GTTATAAAACAAGCAGAAGATAGAGGATTTAATGCTTATGAAATAAAAATAATATTAAGTGAAAATACTCTATTAAAATC TGCAAGAGCTTTTTTAATATTTAAAAACTTAGAAGAGTATGGTGAAATAATAAAATCCTTACCTATAGCAGAAGACATAG AAAATGAAAATTTTGATTTTGAAATAGATTTAATATACTTAACTACTAAAGGTAAAGAAGAAATTTATGATATTTTGGCA AATATATCTGAAGTAGATAATGTTATGGTCGATAATGTAGATGTACAGTTAAAAAGGGAAGAAAAAATAGAAAGTAGAGA AGTAAAAGAAAAAGTAAAAGAGCAAATAAATAATATAGATACAAAAAAACCAGAGGAAGAAAATACAGATAAGAAAACTA AAGTAGAAGAAAATAAACCAAAGGCTAATAAAAGGGTAGCAAAACCAAAGGAAAATAATCATAAAAAAGCTCACCAATCC GTAAGAGTAGATCTTGAAAGACTAGATAAATTTATGAATATGGTTTCAGAGCTTGTAATCCATAGAACTAGATTAGAACA AATAAGTACTAATCACAAGCTAACAGATTTAAATGAAACTTTGGAACAAGTAGCAAGAACTACCTCTGACTTGCAAGATT TGGTTATGAAAATAAGAATGCTTCCTTTAGATATAGTATTTAATAGATTCCCAAGAATGGTTAGAGACCTTTCTGTAGAG TTAGACAAAGAAATGGAACTTATAGTACAAGGTGCAGACACAGAATTAGATAGAACAGTAATAGATGAAATTGGAGAACC TCTAATCCATTTAATAAGAAATGCAGCAGACCATGGTGTAGAACCAAGGGAGGAAAGAGTAAAAAAAGGCAAAGATCCTA TAGGAAAGATAAGATTAATAGCTTATCAAGAAGGAACAAAAGCTGTTATAAAAGTAGAAGATGATGGTGGCGGTGTACCT GTTGACAAAGTAAAAGCTAAAGCAGAAAGAATAGGTATAAATACCGAGGGAATGTCAGACAATGATATAAGAAATTTAAT ATTTGCTCAAGGATTTAGTACTAATGAAAAAGTAACAGACATATCTGGTAGAGGAGTAGGTATGGATGTAGTAAAAACTA AAATTACTGCATTAGGTGGTACTGTAGATCTTATAAGCGAAGAAGGAAAGGGCTCCTCTTTTATAATAAGACTTCCTTTA ACGCTACAAATAATACAAGCTCTTTTAGTTGAAGTTGGAAATGAAACTATGGCTATATCCTTAGGTTATATAGATAGAGT AATAGATTATGAAAAAGATATAGTAAAGAAAACTAATAATAAAGAAGTTATAATATATAGAGGGAATGTAATACCATTTG TTAGAGTAAATGAAAAACTAGGACTTCAAGAATCAGAAAATGATAAAAAATACATAGTAATAGTTAAATCTGGTGAAAAA ACTGTAGGACTTTTAGTAGATGGTCTTTTAGGTCAAAAGGAAATAGTTATAAAACCATTTGGTAAAACACTACAAGGACT AAAAGAATATATAGGAGCAACCATATTAGGAGATGGACTTGTAACATTAATCTTAGACGTGGCAGCTTTAGTATGA
Upstream 100 bases:
>100_bases ACTTTTTGTAGGAGCTACAGAAAGCATTTATAATTATAAAGATTATGGTTTTGAGAAGGTGTCTACATTTATATATAGAA AAATATAAGGGGGAAGTAAC
Downstream 100 bases:
>100_bases TAAAATCATAGGAGGGCTTATATATATGGATTACAATAGTATGACGCCTCTTCAATTAGATGCACTTAAGGAAGTATCTA ATATAGGAACAGGAAATGCG
Product: chemotaxis protein CheA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 691; Mature: 691
Protein sequence:
>691_residues MDTSQYMSMFLEESMDNLQTLNDSLLQLEQEPDDIDKLNEIFRVAHTIKGMAATMGFNEMSELTHKMEDVLSNFREGDLK VTQNVVTVLFKCLDTLEQMVNNISEEVDEKVPIDHIIEELEKAANGDISSQENEKEAIETIEGNKSEGNSTIPLNEYDLN VIKQAEDRGFNAYEIKIILSENTLLKSARAFLIFKNLEEYGEIIKSLPIAEDIENENFDFEIDLIYLTTKGKEEIYDILA NISEVDNVMVDNVDVQLKREEKIESREVKEKVKEQINNIDTKKPEEENTDKKTKVEENKPKANKRVAKPKENNHKKAHQS VRVDLERLDKFMNMVSELVIHRTRLEQISTNHKLTDLNETLEQVARTTSDLQDLVMKIRMLPLDIVFNRFPRMVRDLSVE LDKEMELIVQGADTELDRTVIDEIGEPLIHLIRNAADHGVEPREERVKKGKDPIGKIRLIAYQEGTKAVIKVEDDGGGVP VDKVKAKAERIGINTEGMSDNDIRNLIFAQGFSTNEKVTDISGRGVGMDVVKTKITALGGTVDLISEEGKGSSFIIRLPL TLQIIQALLVEVGNETMAISLGYIDRVIDYEKDIVKKTNNKEVIIYRGNVIPFVRVNEKLGLQESENDKKYIVIVKSGEK TVGLLVDGLLGQKEIVIKPFGKTLQGLKEYIGATILGDGLVTLILDVAALV
Sequences:
>Translated_691_residues MDTSQYMSMFLEESMDNLQTLNDSLLQLEQEPDDIDKLNEIFRVAHTIKGMAATMGFNEMSELTHKMEDVLSNFREGDLK VTQNVVTVLFKCLDTLEQMVNNISEEVDEKVPIDHIIEELEKAANGDISSQENEKEAIETIEGNKSEGNSTIPLNEYDLN VIKQAEDRGFNAYEIKIILSENTLLKSARAFLIFKNLEEYGEIIKSLPIAEDIENENFDFEIDLIYLTTKGKEEIYDILA NISEVDNVMVDNVDVQLKREEKIESREVKEKVKEQINNIDTKKPEEENTDKKTKVEENKPKANKRVAKPKENNHKKAHQS VRVDLERLDKFMNMVSELVIHRTRLEQISTNHKLTDLNETLEQVARTTSDLQDLVMKIRMLPLDIVFNRFPRMVRDLSVE LDKEMELIVQGADTELDRTVIDEIGEPLIHLIRNAADHGVEPREERVKKGKDPIGKIRLIAYQEGTKAVIKVEDDGGGVP VDKVKAKAERIGINTEGMSDNDIRNLIFAQGFSTNEKVTDISGRGVGMDVVKTKITALGGTVDLISEEGKGSSFIIRLPL TLQIIQALLVEVGNETMAISLGYIDRVIDYEKDIVKKTNNKEVIIYRGNVIPFVRVNEKLGLQESENDKKYIVIVKSGEK TVGLLVDGLLGQKEIVIKPFGKTLQGLKEYIGATILGDGLVTLILDVAALV >Mature_691_residues MDTSQYMSMFLEESMDNLQTLNDSLLQLEQEPDDIDKLNEIFRVAHTIKGMAATMGFNEMSELTHKMEDVLSNFREGDLK VTQNVVTVLFKCLDTLEQMVNNISEEVDEKVPIDHIIEELEKAANGDISSQENEKEAIETIEGNKSEGNSTIPLNEYDLN VIKQAEDRGFNAYEIKIILSENTLLKSARAFLIFKNLEEYGEIIKSLPIAEDIENENFDFEIDLIYLTTKGKEEIYDILA NISEVDNVMVDNVDVQLKREEKIESREVKEKVKEQINNIDTKKPEEENTDKKTKVEENKPKANKRVAKPKENNHKKAHQS VRVDLERLDKFMNMVSELVIHRTRLEQISTNHKLTDLNETLEQVARTTSDLQDLVMKIRMLPLDIVFNRFPRMVRDLSVE LDKEMELIVQGADTELDRTVIDEIGEPLIHLIRNAADHGVEPREERVKKGKDPIGKIRLIAYQEGTKAVIKVEDDGGGVP VDKVKAKAERIGINTEGMSDNDIRNLIFAQGFSTNEKVTDISGRGVGMDVVKTKITALGGTVDLISEEGKGSSFIIRLPL TLQIIQALLVEVGNETMAISLGYIDRVIDYEKDIVKKTNNKEVIIYRGNVIPFVRVNEKLGLQESENDKKYIVIVKSGEK TVGLLVDGLLGQKEIVIKPFGKTLQGLKEYIGATILGDGLVTLILDVAALV
Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]
COG id: COG0643
COG function: function code NT; Chemotaxis protein histidine kinase and related kinases
Gene ontology:
Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HPt domain [H]
Homologues:
Organism=Escherichia coli, GI1788197, Length=704, Percent_Identity=32.9545454545455, Blast_Score=335, Evalue=8e-93,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR002545 - InterPro: IPR004358 - InterPro: IPR008207 - InterPro: IPR004105 - InterPro: IPR005467 - InterPro: IPR009082 - InterPro: IPR010808 [H]
Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 77980; Mature: 77980
Theoretical pI: Translated: 4.55; Mature: 4.55
Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDTSQYMSMFLEESMDNLQTLNDSLLQLEQEPDDIDKLNEIFRVAHTIKGMAATMGFNEM CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH SELTHKMEDVLSNFREGDLKVTQNVVTVLFKCLDTLEQMVNNISEEVDEKVPIDHIIEEL HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH EKAANGDISSQENEKEAIETIEGNKSEGNSTIPLNEYDLNVIKQAEDRGFNAYEIKIILS HHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEE ENTLLKSARAFLIFKNLEEYGEIIKSLPIAEDIENENFDFEIDLIYLTTKGKEEIYDILA CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEECCCHHHHHHHHH NISEVDNVMVDNVDVQLKREEKIESREVKEKVKEQINNIDTKKPEEENTDKKTKVEENKP HHHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCC KANKRVAKPKENNHKKAHQSVRVDLERLDKFMNMVSELVIHRTRLEQISTNHKLTDLNET CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH LEQVARTTSDLQDLVMKIRMLPLDIVFNRFPRMVRDLSVELDKEMELIVQGADTELDRTV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCHHHHHH IDEIGEPLIHLIRNAADHGVEPREERVKKGKDPIGKIRLIAYQEGTKAVIKVEDDGGGVP HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCCCCCC VDKVKAKAERIGINTEGMSDNDIRNLIFAQGFSTNEKVTDISGRGVGMDVVKTKITALGG HHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCC TVDLISEEGKGSSFIIRLPLTLQIIQALLVEVGNETMAISLGYIDRVIDYEKDIVKKTNN HHEEECCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCC KEVIIYRGNVIPFVRVNEKLGLQESENDKKYIVIVKSGEKTVGLLVDGLLGQKEIVIKPF CEEEEEECCEEEEEEECHHCCCCCCCCCCEEEEEEECCCCEEHHHHHHHCCCCEEEEECC GKTLQGLKEYIGATILGDGLVTLILDVAALV HHHHHHHHHHHCHHHHCCHHHHHHHHHHHHC >Mature Secondary Structure MDTSQYMSMFLEESMDNLQTLNDSLLQLEQEPDDIDKLNEIFRVAHTIKGMAATMGFNEM CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH SELTHKMEDVLSNFREGDLKVTQNVVTVLFKCLDTLEQMVNNISEEVDEKVPIDHIIEEL HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH EKAANGDISSQENEKEAIETIEGNKSEGNSTIPLNEYDLNVIKQAEDRGFNAYEIKIILS HHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEE ENTLLKSARAFLIFKNLEEYGEIIKSLPIAEDIENENFDFEIDLIYLTTKGKEEIYDILA CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEECCCHHHHHHHHH NISEVDNVMVDNVDVQLKREEKIESREVKEKVKEQINNIDTKKPEEENTDKKTKVEENKP HHHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCC KANKRVAKPKENNHKKAHQSVRVDLERLDKFMNMVSELVIHRTRLEQISTNHKLTDLNET CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH LEQVARTTSDLQDLVMKIRMLPLDIVFNRFPRMVRDLSVELDKEMELIVQGADTELDRTV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCHHHHHH IDEIGEPLIHLIRNAADHGVEPREERVKKGKDPIGKIRLIAYQEGTKAVIKVEDDGGGVP HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCCCCCC VDKVKAKAERIGINTEGMSDNDIRNLIFAQGFSTNEKVTDISGRGVGMDVVKTKITALGG HHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCC TVDLISEEGKGSSFIIRLPLTLQIIQALLVEVGNETMAISLGYIDRVIDYEKDIVKKTNN HHEEECCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCC KEVIIYRGNVIPFVRVNEKLGLQESENDKKYIVIVKSGEKTVGLLVDGLLGQKEIVIKPF CEEEEEECCEEEEEEECHHCCCCCCCCCCEEEEEEECCCCEEHHHHHHHCCCCEEEEECC GKTLQGLKEYIGATILGDGLVTLILDVAALV HHHHHHHHHHHCHHHHCCHHHHHHHHHHHHC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1938941; 9384377 [H]