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The map label for this gene is prdA [H]

Identifier: 226949830

GI number: 226949830

Start: 2788847

End: 2790955

Strand: Reverse

Name: prdA [H]

Synonym: CLM_2776

Alternate gene names: 226949830

Gene position: 2790955-2788847 (Counterclockwise)

Preceding gene: 226949831

Following gene: 226949829

Centisome position: 67.17

GC content: 33.19

Gene sequence:

>2109_bases
ATGTCAATGACAGCTGAACATGCAGAAGAATTAAAAAATGAACATGCTGTAGTTTGTTGTAGAACAGAAGAAGGAACAAT
ATTATCAGCAGATAATTTAGAAGATCCAGAAATATTTCCGGATATGGTAGATTCAGGACTATTAACTATCCCAGATAATT
GTTTGAAAGTTGGAGAAGTAATAGGTGCTAAATTGTTGAAAACTGTAGATTCATTAACTCCACTAACTTCAGATATAGTA
GAGGGTGCTAAAAAAATAGGCAAAGAAGATAAAGAAGATTCTACTACTGAAGAAGCATTGACTGAAGGAAATGAAAAAGC
AGTTTTAAAATATAACCTAAAAGCAGGAGATATTATAAAAGCTAGTGATTTAGAAAACCCAATGCATTTCCCTAAACTTG
TAGATTCTCTTTTAATTTCATTAGATGAAAGAGTACTTACAAGAGAAGAAGTTGTGGGGGCTAAATTAAGTGTAGATACA
CCAGCTTTAACTCCTGTAACAGCAGATATATTAGAAGGATTTGAGGAGGAAGTAAACATGAGTGTTGATTCAAAAGCAAC
AGTAAGTGGTGGAACTTTAAGAATCAAAATTGCTGAAGGTAGAGGAATTGATATAGAAGTTCCTTTAAATGGCAATGTAG
GTGCTGGAAAATCAGCAAAGGTTCCAACAGTAAAAGCTGAAAAAGGTGAAGTAGTAGCAGCTCCAGCAGTAGAAGCTAAT
AAAGAAGTTAAATTAGAAGAAAAAGTTATAAGAAGTCTTACTAGAAAACATTATAAAATAGACAAAATAGAATTTGGCTC
TGAAACAAAAATAGAAGGAACAACTCTTTATATAAGAGAAGGGATTTCTCAAGATGCTAAGAATGTGAGCTCACTAGTAA
AAGATGTCAAAATAGATATAATAACTCCAGATAAATACAATACTTATAGTGAAACTATAATGGATGTACAACCAATTGCT
ACTAAAGAAGGAGATAACAAATTAGGAACAGGTGTAACTAGAGTATTAGATGGTGTTATTGTAATGGTAACAGGAACAGA
TGAAAATGGAGTCCAAATAGGTGAATTTGGTTCTTCAGAAGGTATATTAGAAGAAAACATTATGTTCAATAGACCAGGAT
CACCAGATAAAGGTGAAATATTTATAAAAACACAAGTAACTATAAAAGAAAAGACTAATATGGAAAGACCAGGTCCTATG
GCTGCTCACAAAGCTACTGATTTCATAACTCAAGAAATAAGGGAAGCTATGAAAGCTTTAGAGGATGAGTCTTTAGTAGT
TAATACTGAAACTTTTGAACAAAAAAGAAGACCAGGAAAGAAAAAAGTTGTAGTTGTTAAAGAAATAATGGGTCAAGGTG
CTATGCACGACAACTTAATATTACCAGTAGAACCAGTAGGTTATTTAGGTGGTAAACCAAATGTTGATTTAGGAAATGTT
CCAGTAATGCTTTCACCACTTGAAGTATTAGATGGTGGTATACATGCATTAACTTGTATTGGACCTGCTTCTAAAGAATG
TTCAAGACATTATTGGAGAGAACCTCTTGTAATGGAATGCATGAAGGATGAAGAATTAGACTTATGCGGAGTTATATTTG
TAGGAAGTCCACAAATCAACAGTGAAAAATTCTACGTATCAGAAAGAATGGGTATGATGGTAGAAGCGTTAGATGTTGAT
GGTGCCTTTGTTACAACTGAAGGCTTTGGAAATAATCACATTGACTTTGCGAGCCACGTAGAACAAATAGGTATGAGAGG
AATACCATGTGTAGCATTCTCATTCTGTGCAGTTCAAGGTGCTCTAGTTGTTGGTAATAAATACATGAAATATATGATAG
ATAATAACAAATCAGAAGGCGGAATAGAAAACGAAGTATTAGAATGCAACACATTATGTCCAGAAGATGCAATAAGAGGT
GTTGAAATGCTTAAAGCTGCTATGGCTGGAGAAGATGTTAAAAAACCAGAAAGAGCTTGGAATGCAAATGTTAAAGAAAA
CAACTTAGAATTAATAGAAAAAGCTGAAAATGTAAAAATAGAAAGAGTTTTAAATGAAGCTTCAATACCAATGAGTGAGA
AGAGAAAAGAAAAATACAGCACAAAGTAG

Upstream 100 bases:

>100_bases
ATATCATCATACCGACCATATATTTAGAACAATTGATTATACATTAACAAGAAGACTTAAAGAGGAAGAAAAATAATAAA
AAGTTAGGAGGTAATTTGAG

Downstream 100 bases:

>100_bases
GGATATAAATGGATTTAAAATACGGTGATAAGATCATAGAAATGGAAGGCGTTATCGTAGAAGTATCCGATGGTGCAGTA
GCTATAGATTTTAAAGGAAG

Product: D-proline reductase, PrdA proprotein

Products: NA

Alternate protein names: D-proline reductase 45 kDa subunit; D-proline reductase 23 kDa subunit [H]

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MSMTAEHAEELKNEHAVVCCRTEEGTILSADNLEDPEIFPDMVDSGLLTIPDNCLKVGEVIGAKLLKTVDSLTPLTSDIV
EGAKKIGKEDKEDSTTEEALTEGNEKAVLKYNLKAGDIIKASDLENPMHFPKLVDSLLISLDERVLTREEVVGAKLSVDT
PALTPVTADILEGFEEEVNMSVDSKATVSGGTLRIKIAEGRGIDIEVPLNGNVGAGKSAKVPTVKAEKGEVVAAPAVEAN
KEVKLEEKVIRSLTRKHYKIDKIEFGSETKIEGTTLYIREGISQDAKNVSSLVKDVKIDIITPDKYNTYSETIMDVQPIA
TKEGDNKLGTGVTRVLDGVIVMVTGTDENGVQIGEFGSSEGILEENIMFNRPGSPDKGEIFIKTQVTIKEKTNMERPGPM
AAHKATDFITQEIREAMKALEDESLVVNTETFEQKRRPGKKKVVVVKEIMGQGAMHDNLILPVEPVGYLGGKPNVDLGNV
PVMLSPLEVLDGGIHALTCIGPASKECSRHYWREPLVMECMKDEELDLCGVIFVGSPQINSEKFYVSERMGMMVEALDVD
GAFVTTEGFGNNHIDFASHVEQIGMRGIPCVAFSFCAVQGALVVGNKYMKYMIDNNKSEGGIENEVLECNTLCPEDAIRG
VEMLKAAMAGEDVKKPERAWNANVKENNLELIEKAENVKIERVLNEASIPMSEKRKEKYSTK

Sequences:

>Translated_702_residues
MSMTAEHAEELKNEHAVVCCRTEEGTILSADNLEDPEIFPDMVDSGLLTIPDNCLKVGEVIGAKLLKTVDSLTPLTSDIV
EGAKKIGKEDKEDSTTEEALTEGNEKAVLKYNLKAGDIIKASDLENPMHFPKLVDSLLISLDERVLTREEVVGAKLSVDT
PALTPVTADILEGFEEEVNMSVDSKATVSGGTLRIKIAEGRGIDIEVPLNGNVGAGKSAKVPTVKAEKGEVVAAPAVEAN
KEVKLEEKVIRSLTRKHYKIDKIEFGSETKIEGTTLYIREGISQDAKNVSSLVKDVKIDIITPDKYNTYSETIMDVQPIA
TKEGDNKLGTGVTRVLDGVIVMVTGTDENGVQIGEFGSSEGILEENIMFNRPGSPDKGEIFIKTQVTIKEKTNMERPGPM
AAHKATDFITQEIREAMKALEDESLVVNTETFEQKRRPGKKKVVVVKEIMGQGAMHDNLILPVEPVGYLGGKPNVDLGNV
PVMLSPLEVLDGGIHALTCIGPASKECSRHYWREPLVMECMKDEELDLCGVIFVGSPQINSEKFYVSERMGMMVEALDVD
GAFVTTEGFGNNHIDFASHVEQIGMRGIPCVAFSFCAVQGALVVGNKYMKYMIDNNKSEGGIENEVLECNTLCPEDAIRG
VEMLKAAMAGEDVKKPERAWNANVKENNLELIEKAENVKIERVLNEASIPMSEKRKEKYSTK
>Mature_701_residues
SMTAEHAEELKNEHAVVCCRTEEGTILSADNLEDPEIFPDMVDSGLLTIPDNCLKVGEVIGAKLLKTVDSLTPLTSDIVE
GAKKIGKEDKEDSTTEEALTEGNEKAVLKYNLKAGDIIKASDLENPMHFPKLVDSLLISLDERVLTREEVVGAKLSVDTP
ALTPVTADILEGFEEEVNMSVDSKATVSGGTLRIKIAEGRGIDIEVPLNGNVGAGKSAKVPTVKAEKGEVVAAPAVEANK
EVKLEEKVIRSLTRKHYKIDKIEFGSETKIEGTTLYIREGISQDAKNVSSLVKDVKIDIITPDKYNTYSETIMDVQPIAT
KEGDNKLGTGVTRVLDGVIVMVTGTDENGVQIGEFGSSEGILEENIMFNRPGSPDKGEIFIKTQVTIKEKTNMERPGPMA
AHKATDFITQEIREAMKALEDESLVVNTETFEQKRRPGKKKVVVVKEIMGQGAMHDNLILPVEPVGYLGGKPNVDLGNVP
VMLSPLEVLDGGIHALTCIGPASKECSRHYWREPLVMECMKDEELDLCGVIFVGSPQINSEKFYVSERMGMMVEALDVDG
AFVTTEGFGNNHIDFASHVEQIGMRGIPCVAFSFCAVQGALVVGNKYMKYMIDNNKSEGGIENEVLECNTLCPEDAIRGV
EMLKAAMAGEDVKKPERAWNANVKENNLELIEKAENVKIERVLNEASIPMSEKRKEKYSTK

Specific function: D-proline reductase catalyzes the reductive cleavage of a C-N bond in D-proline resulting in the formation of 5- aminovalerate. The alpha subunit has been shown to bind D-proline, presumably via the pyruvoyl group [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015417 [H]

Pfam domain/function: PF09338 Gly_reductase [H]

EC number: =1.21.4.1 [H]

Molecular weight: Translated: 76705; Mature: 76573

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTAEHAEELKNEHAVVCCRTEEGTILSADNLEDPEIFPDMVDSGLLTIPDNCLKVGEV
CCCCHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCCHHHHCCCCEECCHHHHHHHHH
IGAKLLKTVDSLTPLTSDIVEGAKKIGKEDKEDSTTEEALTEGNEKAVLKYNLKAGDIIK
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCEEE
ASDLENPMHFPKLVDSLLISLDERVLTREEVVGAKLSVDTPALTPVTADILEGFEEEVNM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHCC
SVDSKATVSGGTLRIKIAEGRGIDIEVPLNGNVGAGKSAKVPTVKAEKGEVVAAPAVEAN
CCCCCEEECCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEECCCCCEEEECCCCCC
KEVKLEEKVIRSLTRKHYKIDKIEFGSETKIEGTTLYIREGISQDAKNVSSLVKDVKIDI
CCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCEEEE
ITPDKYNTYSETIMDVQPIATKEGDNKLGTGVTRVLDGVIVMVTGTDENGVQIGEFGSSE
ECCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCEEECCCCCCC
GILEENIMFNRPGSPDKGEIFIKTQVTIKEKTNMERPGPMAAHKATDFITQEIREAMKAL
CCCCCCEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
EDESLVVNTETFEQKRRPGKKKVVVVKEIMGQGAMHDNLILPVEPVGYLGGKPNVDLGNV
CCCCEEEECHHHHHHHCCCCCEEEEHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
PVMLSPLEVLDGGIHALTCIGPASKECSRHYWREPLVMECMKDEELDLCGVIFVGSPQIN
CEEECCHHHHCCCCEEEEEECCCHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEECCCCCC
SEKFYVSERMGMMVEALDVDGAFVTTEGFGNNHIDFASHVEQIGMRGIPCVAFSFCAVQG
CCEEEHHHHHCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHC
ALVVGNKYMKYMIDNNKSEGGIENEVLECNTLCPEDAIRGVEMLKAAMAGEDVKKPERAW
EEEECCCEEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
NANVKENNLELIEKAENVKIERVLNEASIPMSEKRKEKYSTK
CCCCCCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SMTAEHAEELKNEHAVVCCRTEEGTILSADNLEDPEIFPDMVDSGLLTIPDNCLKVGEV
CCCHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCCHHHHCCCCEECCHHHHHHHHH
IGAKLLKTVDSLTPLTSDIVEGAKKIGKEDKEDSTTEEALTEGNEKAVLKYNLKAGDIIK
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCEEE
ASDLENPMHFPKLVDSLLISLDERVLTREEVVGAKLSVDTPALTPVTADILEGFEEEVNM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHCC
SVDSKATVSGGTLRIKIAEGRGIDIEVPLNGNVGAGKSAKVPTVKAEKGEVVAAPAVEAN
CCCCCEEECCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEECCCCCEEEECCCCCC
KEVKLEEKVIRSLTRKHYKIDKIEFGSETKIEGTTLYIREGISQDAKNVSSLVKDVKIDI
CCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCEEEE
ITPDKYNTYSETIMDVQPIATKEGDNKLGTGVTRVLDGVIVMVTGTDENGVQIGEFGSSE
ECCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCEEECCCCCCC
GILEENIMFNRPGSPDKGEIFIKTQVTIKEKTNMERPGPMAAHKATDFITQEIREAMKAL
CCCCCCEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
EDESLVVNTETFEQKRRPGKKKVVVVKEIMGQGAMHDNLILPVEPVGYLGGKPNVDLGNV
CCCCEEEECHHHHHHHCCCCCEEEEHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
PVMLSPLEVLDGGIHALTCIGPASKECSRHYWREPLVMECMKDEELDLCGVIFVGSPQIN
CEEECCHHHHCCCCEEEEEECCCHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEECCCCCC
SEKFYVSERMGMMVEALDVDGAFVTTEGFGNNHIDFASHVEQIGMRGIPCVAFSFCAVQG
CCEEEHHHHHCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHC
ALVVGNKYMKYMIDNNKSEGGIENEVLECNTLCPEDAIRGVEMLKAAMAGEDVKKPERAW
EEEECCCEEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
NANVKENNLELIEKAENVKIERVLNEASIPMSEKRKEKYSTK
CCCCCCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10085076 [H]