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The map label for this gene is 226949727

Identifier: 226949727

GI number: 226949727

Start: 2681868

End: 2683238

Strand: Reverse

Name: 226949727

Synonym: CLM_2667

Alternate gene names: NA

Gene position: 2683238-2681868 (Counterclockwise)

Preceding gene: 226949728

Following gene: 226949726

Centisome position: 64.57

GC content: 31.22

Gene sequence:

>1371_bases
ATGAATTTTAAACCTTGGAATTATCAGCAATATTCCATCAACCACATTATAGATCACAGCGCTTCAGGTCTATTTCTAGA
TATGGGTATGGGTAAAACTGTTAGTACACTAACTGCAATAGATGATTTACTATTTCTTGGTGAATCCGAGAAGATATTGG
TAATAGCACCTTTAAGAGTGGCGGAAGATACATGGAGTACAGAAGTAGATAAGTGGGACCATATCAATCATCTAAAAATA
TCTAAGATTTTAGGTACACCAAAACAAAGAAAGGAAGCAGTAGAAAAGGATGCAGACATATACGTAACCAATAGGGAAAA
TGTGGTTTGGTTAGTAGATAATTATTTTAAACAATGGAAATGGGATACATGTATCGTAGATGAATTAAGTTCCTTTAAAT
CTTCTAAGGCTAAAAGGTTTAGAGCTTTAAAGAAAGTTAGGCCATACTTTAAAAGAATGGTAGGACTTACTGGAACCCCA
GCACCTAATAGTTTAATAGATTTATGGCCACAAATTTATTTGTTAGATGGTGGTAAAAGATTAGGTAGAACCATCACAAG
TTACAGGCAACAGTATTTTAACCCAGGAAAAAGAAATCAATATATAGTTTATAATTGGGAGCTAAAAGATGGAGCAGAAG
AACAGATCCATAAAAAGATAGGTGATATTTGTATTTCTATGATGGCCAAAGATTATTTAGATATTCCTGAAAGAATTGAT
AATATAATTGATATCAATTTACCTAAAAATGCAATAAATAAATATAAGCAACTAGAAAAGGATTTAGTATTAGAATTAGG
TGAAGATGATATTACAGCAGCTAATGCAGCAGTACTTACTAATAAATTATTACAAATGTCTAATGGGGCAATATATTCAG
AGGACAAGCAGGTTATAGAAATTCATGACGAAAAACTAAAAGCTTTATTAGATATTATTGAATCAGCTAATGGTAAACCA
GTTTTGATATTTTATAGCTTCAAACATGACTTTGATAGAATAGTCAATTTTTTTAAATCTAAAAAGTTAAATGCAATAGG
ATTAGGAGATTCAAAGGATATTAAAAAATGGAATAATGGAGAAATACCTATACTTTTAGTACATCCAGCTTCAGCAGGGC
ATGGATTAAATCTTCAATATGGGGGCAATATTATTGTTTGGTTTGGGCTTACATGGAGTTTAGAGTTATATCAACAGGCT
AATGCAAGACTTCATAGGCAAGGACAAAAGGAAAGTGTTATAATTCATCATCTAGTAAGTAAGGATACTGTAGATGAAGA
TGTTATAAAAACTTTAGGTAGTAAAGAAGTTAATCAGAACGTATTACTAGAAGCAGTAAAAGCAAGATTAAAAACATATA
AGGAGGTTTAG

Upstream 100 bases:

>100_bases
TAGCATTAATACCATGCGAAACTAAAAAAGGTACTAAATATGTTGGAATTTTTGATAACACTAATGGTAAAGAATATGCA
ATGATTAGGGATGAGTAATT

Downstream 100 bases:

>100_bases
TATGATAGATAATATAAATATAGATGAGGTTATAAGTAAAGCCACTAAAGAAGCTATAAGAGAATATGATAAAGAAAAAA
GTATTATTCAAAAGGATAAA

Product: SNF2 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MNFKPWNYQQYSINHIIDHSASGLFLDMGMGKTVSTLTAIDDLLFLGESEKILVIAPLRVAEDTWSTEVDKWDHINHLKI
SKILGTPKQRKEAVEKDADIYVTNRENVVWLVDNYFKQWKWDTCIVDELSSFKSSKAKRFRALKKVRPYFKRMVGLTGTP
APNSLIDLWPQIYLLDGGKRLGRTITSYRQQYFNPGKRNQYIVYNWELKDGAEEQIHKKIGDICISMMAKDYLDIPERID
NIIDINLPKNAINKYKQLEKDLVLELGEDDITAANAAVLTNKLLQMSNGAIYSEDKQVIEIHDEKLKALLDIIESANGKP
VLIFYSFKHDFDRIVNFFKSKKLNAIGLGDSKDIKKWNNGEIPILLVHPASAGHGLNLQYGGNIIVWFGLTWSLELYQQA
NARLHRQGQKESVIIHHLVSKDTVDEDVIKTLGSKEVNQNVLLEAVKARLKTYKEV

Sequences:

>Translated_456_residues
MNFKPWNYQQYSINHIIDHSASGLFLDMGMGKTVSTLTAIDDLLFLGESEKILVIAPLRVAEDTWSTEVDKWDHINHLKI
SKILGTPKQRKEAVEKDADIYVTNRENVVWLVDNYFKQWKWDTCIVDELSSFKSSKAKRFRALKKVRPYFKRMVGLTGTP
APNSLIDLWPQIYLLDGGKRLGRTITSYRQQYFNPGKRNQYIVYNWELKDGAEEQIHKKIGDICISMMAKDYLDIPERID
NIIDINLPKNAINKYKQLEKDLVLELGEDDITAANAAVLTNKLLQMSNGAIYSEDKQVIEIHDEKLKALLDIIESANGKP
VLIFYSFKHDFDRIVNFFKSKKLNAIGLGDSKDIKKWNNGEIPILLVHPASAGHGLNLQYGGNIIVWFGLTWSLELYQQA
NARLHRQGQKESVIIHHLVSKDTVDEDVIKTLGSKEVNQNVLLEAVKARLKTYKEV
>Mature_456_residues
MNFKPWNYQQYSINHIIDHSASGLFLDMGMGKTVSTLTAIDDLLFLGESEKILVIAPLRVAEDTWSTEVDKWDHINHLKI
SKILGTPKQRKEAVEKDADIYVTNRENVVWLVDNYFKQWKWDTCIVDELSSFKSSKAKRFRALKKVRPYFKRMVGLTGTP
APNSLIDLWPQIYLLDGGKRLGRTITSYRQQYFNPGKRNQYIVYNWELKDGAEEQIHKKIGDICISMMAKDYLDIPERID
NIIDINLPKNAINKYKQLEKDLVLELGEDDITAANAAVLTNKLLQMSNGAIYSEDKQVIEIHDEKLKALLDIIESANGKP
VLIFYSFKHDFDRIVNFFKSKKLNAIGLGDSKDIKKWNNGEIPILLVHPASAGHGLNLQYGGNIIVWFGLTWSLELYQQA
NARLHRQGQKESVIIHHLVSKDTVDEDVIKTLGSKEVNQNVLLEAVKARLKTYKEV

Specific function: Unknown

COG id: COG0553

COG function: function code KL; Superfamily II DNA/RNA helicases, SNF2 family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SWIM-type zinc finger [H]

Homologues:

Organism=Homo sapiens, GI48255900, Length=486, Percent_Identity=24.6913580246914, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI48255898, Length=480, Percent_Identity=24.375, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551114, Length=462, Percent_Identity=24.4588744588745, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI115534248, Length=164, Percent_Identity=33.5365853658537, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319547, Length=473, Percent_Identity=23.2558139534884, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322065, Length=452, Percent_Identity=24.1150442477876, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324864, Length=456, Percent_Identity=24.3421052631579, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324879, Length=476, Percent_Identity=23.7394957983193, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321012, Length=464, Percent_Identity=23.2758620689655, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR000330
- InterPro:   IPR007527 [H]

Pfam domain/function: PF00271 Helicase_C; PF00176 SNF2_N; PF04434 SWIM [H]

EC number: NA

Molecular weight: Translated: 52274; Mature: 52274

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKPWNYQQYSINHIIDHSASGLFLDMGMGKTVSTLTAIDDLLFLGESEKILVIAPLRV
CCCCCCCCCEEEHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECCEE
AEDTWSTEVDKWDHINHLKISKILGTPKQRKEAVEKDADIYVTNRENVVWLVDNYFKQWK
CCCCCCCCCCCCCCCCCEEHHHHHCCCHHHHHHHCCCCCEEEECCCCEEEEEEHHHHHCC
WDTCIVDELSSFKSSKAKRFRALKKVRPYFKRMVGLTGTPAPNSLIDLWPQIYLLDGGKR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCEEEEEECCHH
LGRTITSYRQQYFNPGKRNQYIVYNWELKDGAEEQIHKKIGDICISMMAKDYLDIPERID
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
NIIDINLPKNAINKYKQLEKDLVLELGEDDITAANAAVLTNKLLQMSNGAIYSEDKQVIE
CEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCEEE
IHDEKLKALLDIIESANGKPVLIFYSFKHDFDRIVNFFKSKKLNAIGLGDSKDIKKWNNG
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEECCCCHHCCCCCCC
EIPILLVHPASAGHGLNLQYGGNIIVWFGLTWSLELYQQANARLHRQGQKESVIIHHLVS
CEEEEEEECCCCCCCEEEEECCCEEEEEECEEHHHHHHHHHHHHHHCCCCCHHHHHHHHC
KDTVDEDVIKTLGSKEVNQNVLLEAVKARLKTYKEV
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFKPWNYQQYSINHIIDHSASGLFLDMGMGKTVSTLTAIDDLLFLGESEKILVIAPLRV
CCCCCCCCCEEEHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECCEE
AEDTWSTEVDKWDHINHLKISKILGTPKQRKEAVEKDADIYVTNRENVVWLVDNYFKQWK
CCCCCCCCCCCCCCCCCEEHHHHHCCCHHHHHHHCCCCCEEEECCCCEEEEEEHHHHHCC
WDTCIVDELSSFKSSKAKRFRALKKVRPYFKRMVGLTGTPAPNSLIDLWPQIYLLDGGKR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCEEEEEECCHH
LGRTITSYRQQYFNPGKRNQYIVYNWELKDGAEEQIHKKIGDICISMMAKDYLDIPERID
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
NIIDINLPKNAINKYKQLEKDLVLELGEDDITAANAAVLTNKLLQMSNGAIYSEDKQVIE
CEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCEEE
IHDEKLKALLDIIESANGKPVLIFYSFKHDFDRIVNFFKSKKLNAIGLGDSKDIKKWNNG
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEECCCCHHCCCCCCC
EIPILLVHPASAGHGLNLQYGGNIIVWFGLTWSLELYQQANARLHRQGQKESVIIHHLVS
CEEEEEEECCCCCCCEEEEECCCEEEEEECEEHHHHHHHHHHHHHHCCCCCHHHHHHHHC
KDTVDEDVIKTLGSKEVNQNVLLEAVKARLKTYKEV
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7569993; 8253680 [H]