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The map label for this gene is sigW [H]

Identifier: 226949672

GI number: 226949672

Start: 2638260

End: 2638772

Strand: Reverse

Name: sigW [H]

Synonym: CLM_2609

Alternate gene names: 226949672

Gene position: 2638772-2638260 (Counterclockwise)

Preceding gene: 226949673

Following gene: 226949671

Centisome position: 63.5

GC content: 29.82

Gene sequence:

>513_bases
GTGATAGTTATTGAAAAAGAACAATTTGCAGACTATATAAAACAATATGAACGTTTAATTATTACTATTTGTCTATCCTT
TACAAAAAATTACTTTGATGCGGAAGATTTGGCACAGCAAACCTTTTTAGCTGCATATCAAAATTATGAAAGATTTGATG
GTAACAACTTTAAAGCTTGGCTTACTACGATTGCTGCAAATAAGTGTAAGGATTATCTTAAGAGTAAAACAAGAACAAAC
GTTAGTTTATCAGAGAAAGAGTATGAGAGTTTGAAAGATCATGGAGATTCTCCCGAGGAAACAGTAGTAAAAAAGAATAC
TATTGAGAGAATATATAGACTATGTAATAAGTTAAAAGAGCCTTACAGAACTGTAGCTATAAGCTATTTTTGCAAAGATA
TCAAACTTTCACATTTGGCAAAGGAAACTGGTAAAAATATTAAAACTTTAGAAACGCAACTTTATAGGTCAAAAAAATTA
CTAAAGGATTTATGGAAGGAGGAGTTTATGTGA

Upstream 100 bases:

>100_bases
AGAAAATGTTATTCAGATAATTTTTAGTATAATTATATTAAATATTGAAGTGTTTTTTATTTCTCAATCGTTATATTAAA
TGTAAGGATAAAAGAAGGTG

Downstream 100 bases:

>100_bases
AGCCTACATTATTTAATAAAGAAGGACATTTAACTGACGATACAGTAAAGTTACTTAAACTTGGCACTCTTAAGGATGAA
GAATTGATTCCCATATTGGA

Product: ECF family RNA polymerase sigma-70 factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MIVIEKEQFADYIKQYERLIITICLSFTKNYFDAEDLAQQTFLAAYQNYERFDGNNFKAWLTTIAANKCKDYLKSKTRTN
VSLSEKEYESLKDHGDSPEETVVKKNTIERIYRLCNKLKEPYRTVAISYFCKDIKLSHLAKETGKNIKTLETQLYRSKKL
LKDLWKEEFM

Sequences:

>Translated_170_residues
MIVIEKEQFADYIKQYERLIITICLSFTKNYFDAEDLAQQTFLAAYQNYERFDGNNFKAWLTTIAANKCKDYLKSKTRTN
VSLSEKEYESLKDHGDSPEETVVKKNTIERIYRLCNKLKEPYRTVAISYFCKDIKLSHLAKETGKNIKTLETQLYRSKKL
LKDLWKEEFM
>Mature_170_residues
MIVIEKEQFADYIKQYERLIITICLSFTKNYFDAEDLAQQTFLAAYQNYERFDGNNFKAWLTTIAANKCKDYLKSKTRTN
VSLSEKEYESLKDHGDSPEETVVKKNTIERIYRLCNKLKEPYRTVAISYFCKDIKLSHLAKETGKNIKTLETQLYRSKKL
LKDLWKEEFM

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20202; Mature: 20202

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVIEKEQFADYIKQYERLIITICLSFTKNYFDAEDLAQQTFLAAYQNYERFDGNNFKAW
CEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
LTTIAANKCKDYLKSKTRTNVSLSEKEYESLKDHGDSPEETVVKKNTIERIYRLCNKLKE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
PYRTVAISYFCKDIKLSHLAKETGKNIKTLETQLYRSKKLLKDLWKEEFM
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVIEKEQFADYIKQYERLIITICLSFTKNYFDAEDLAQQTFLAAYQNYERFDGNNFKAW
CEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
LTTIAANKCKDYLKSKTRTNVSLSEKEYESLKDHGDSPEETVVKKNTIERIYRLCNKLKE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
PYRTVAISYFCKDIKLSHLAKETGKNIKTLETQLYRSKKLLKDLWKEEFM
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]