Click here to switch to the map view.

The map label for this gene is bioD [H]

Identifier: 226949531

GI number: 226949531

Start: 2543832

End: 2544515

Strand: Reverse

Name: bioD [H]

Synonym: CLM_2467

Alternate gene names: 226949531

Gene position: 2544515-2543832 (Counterclockwise)

Preceding gene: 226949532

Following gene: 226949530

Centisome position: 61.24

GC content: 29.39

Gene sequence:

>684_bases
ATGGCAAGAGGAATATTTATAACAGCCACAGGAACTGATATTGGAAAAACTTACGTAACGGCTTTAATTATTAAGAGATT
AAGAGAAACTAATATAAATTGTGGATACTATAAAGCTGCTCTAAGCGAGGCAGAGAGAAGAGATGGTAAACTTATTGCAG
GAGATGCTAACTATGTATATAATATTGCCAACATAAAGGGAGATCCTAATGATGCAGTGAGTTATATATTTCAGCAAGCA
GTTTCTCCTCATTTAGCAGCAAAGTTAAATAATGTAGAAATATCTATGGAGAGGATAAAAAAAGATTTTTACTCTATTAA
AAATAAATATGATTATATAACTGTAGAAGGTAGTGGAGGAATAGTTTGTCCTATTTCCACAGGTAAAGAAAAAATAATGC
TTGACAATATCATAAAGATCTTTAAACTACCGGCTATTGTTGTAGCAGATGCAGGTCTTGGCACCATTAACAGCACAATT
TTAACCCTTCAATATATGAAAGAGAAAAATATATCTGTAAAAATGATTTTATTAAACAATTATAACCATGAAGATATAAT
TCATATAGAAAATAAGGGATACCTATCAGATAATTTACTAATTCCAGTTTATACATGTAATAAGAATGCTAATAATTTAG
AAATTCCAGTAGAAAAACTAATTGAAATCTATGAGGAGATATAA

Upstream 100 bases:

>100_bases
GAGTAAATGGAGCAATTTCTGGAGATATGCTAACTACTTTAGGAATTGAAACTTCTGAGGACATTAAAATGATAAAGAAT
TTAGGATTTGAGGTATAAAT

Downstream 100 bases:

>100_bases
TTTAGCATTTAACGCTATTGACAAACAATATTAATATGGTTAGTGTAATATTAATATTATAATAAATTTAGAATGTTATA
GATTTGATGGGGAAATGGAG

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSEAERRDGKLIAGDANYVYNIANIKGDPNDAVSYIFQQA
VSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGGIVCPISTGKEKIMLDNIIKIFKLPAIVVADAGLGTINSTI
LTLQYMKEKNISVKMILLNNYNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI

Sequences:

>Translated_227_residues
MARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSEAERRDGKLIAGDANYVYNIANIKGDPNDAVSYIFQQA
VSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGGIVCPISTGKEKIMLDNIIKIFKLPAIVVADAGLGTINSTI
LTLQYMKEKNISVKMILLNNYNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI
>Mature_226_residues
ARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSEAERRDGKLIAGDANYVYNIANIKGDPNDAVSYIFQQAV
SPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGGIVCPISTGKEKIMLDNIIKIFKLPAIVVADAGLGTINSTIL
TLQYMKEKNISVKMILLNNYNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=203, Percent_Identity=22.6600985221675, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324385, Length=172, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25387; Mature: 25256

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSEAERRDGKLIAGDANYVY
CCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCEEE
NIANIKGDPNDAVSYIFQQAVSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGG
EEEECCCCCHHHHHHHHHHHCCCHHHHEECCEEEHHHHHHHHHHHHCCCCEEEEEECCCC
IVCPISTGKEKIMLDNIIKIFKLPAIVVADAGLGTINSTILTLQYMKEKNISVKMILLNN
EEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCHHEEEEEEHHCCCCEEEEEEEEC
YNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI
CCCCCEEEECCCCEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
ARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSEAERRDGKLIAGDANYVY
CCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCEEE
NIANIKGDPNDAVSYIFQQAVSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGG
EEEECCCCCHHHHHHHHHHHCCCHHHHEECCEEEHHHHHHHHHHHHCCCCEEEEEECCCC
IVCPISTGKEKIMLDNIIKIFKLPAIVVADAGLGTINSTILTLQYMKEKNISVKMILLNN
EEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCHHEEEEEEHHCCCCEEEEEEEEC
YNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI
CCCCCEEEECCCCEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA