Click here to switch to the map view.

The map label for this gene is ltaE [H]

Identifier: 226949504

GI number: 226949504

Start: 2521731

End: 2522759

Strand: Reverse

Name: ltaE [H]

Synonym: CLM_2439

Alternate gene names: 226949504

Gene position: 2522759-2521731 (Counterclockwise)

Preceding gene: 226949506

Following gene: 226949503

Centisome position: 60.71

GC content: 29.93

Gene sequence:

>1029_bases
ATGTATAGTTTTAAATGCGATTATAGTGAAGGATGTCATCCTAGAATTTTAAAGGCATTAGCAGAGTCAAATATTACTCA
AGAGGAAGGTTATGGAAAAGATTCTCATACTAAAAATGCTATTTCTATAATAAAGAAATTAGTACAAAATGAAAATGTAG
ATATTCATCTTATATCTGGAGGAACTCAAACAAATTTAATTTCGATTAGCTCATTCTTAAGACCTCATGAAGCTTGTATA
TGTGTACATTCAGGTCATATTGCAGGCCCCGAGACTGGTTCCATTGAATATACTGGTCATAAAGTAATTACTGTAGATTC
AACCAATGGAAAAATTACTACAGATAAAATTCAGCAGGTATTAGATTTTCATAGAAACGAGCATTTTGTAAAACCAAAGC
TTGTTTATATTTCTAATTCAACAGAAGTGGGAACAGTATATACCAAAGAAGAAATGAGAAATTTAAGTGAATTTTGTAAA
AAGAAGAACCTTATTTTGTATGTAGATGGTGCAAGGCTTGGTTCCGCTCTTGCTGTTAAAGAGTCAAATTTAACTTTAAA
AGATATGTGTGGTTTTTCAGATGCATTTTGTATTGGTGGGACTAAAAATGGGGCTCTTATAGGAGAAGCTTTAGTTATAA
AAAATCAAAATTTAAAAGAAGATTTTAGATATAATATAAAACAAAAAGGAGCTCTTCTTGCTAAGGGAAGAGTTTTAGGA
ATACAATTTGAGGAACTATTTAAGGATAATCTTTATTTTGATCTTGCAAATCATGCAAATGAAATGGCAAGCATTTTAAC
TAAAGGATTAAAAGATGCCAACTGTGAGTTTTTTGTGGAATCTAAGAGTAATCAAATTTTCCCTATTCTGAGTAATGAAA
ACATAAAAATACTACAAGAAAGATTCTCTTTTAATATTTGGGAGAAGGTAGGCAATAAAAATTCCGCTATTAGATTAGTT
ACTTCCTGGGCAACAACAAAAGAAGTAGTATTTGAATTTATTCAAGAATTAAAACAATTAGTGGAATAG

Upstream 100 bases:

>100_bases
ATCTATCCAGTCATATATTTCTATATAAATTTACAAAAAAAAGTAGTTATGCAAACTTTTTTATAAAAATAAACACTCAA
ATTATAGAGGGGGCTTATAA

Downstream 100 bases:

>100_bases
ATTTTTAAAAATATTTAGATAGATATAATAAAGATTAAAAAATTATAAGGAGAATGTAGAAGGGTCTGTCCCAAAATAGA
TTTAATTTTAATATTTTTAG

Product: putative low specificity L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MYSFKCDYSEGCHPRILKALAESNITQEEGYGKDSHTKNAISIIKKLVQNENVDIHLISGGTQTNLISISSFLRPHEACI
CVHSGHIAGPETGSIEYTGHKVITVDSTNGKITTDKIQQVLDFHRNEHFVKPKLVYISNSTEVGTVYTKEEMRNLSEFCK
KKNLILYVDGARLGSALAVKESNLTLKDMCGFSDAFCIGGTKNGALIGEALVIKNQNLKEDFRYNIKQKGALLAKGRVLG
IQFEELFKDNLYFDLANHANEMASILTKGLKDANCEFFVESKSNQIFPILSNENIKILQERFSFNIWEKVGNKNSAIRLV
TSWATTKEVVFEFIQELKQLVE

Sequences:

>Translated_342_residues
MYSFKCDYSEGCHPRILKALAESNITQEEGYGKDSHTKNAISIIKKLVQNENVDIHLISGGTQTNLISISSFLRPHEACI
CVHSGHIAGPETGSIEYTGHKVITVDSTNGKITTDKIQQVLDFHRNEHFVKPKLVYISNSTEVGTVYTKEEMRNLSEFCK
KKNLILYVDGARLGSALAVKESNLTLKDMCGFSDAFCIGGTKNGALIGEALVIKNQNLKEDFRYNIKQKGALLAKGRVLG
IQFEELFKDNLYFDLANHANEMASILTKGLKDANCEFFVESKSNQIFPILSNENIKILQERFSFNIWEKVGNKNSAIRLV
TSWATTKEVVFEFIQELKQLVE
>Mature_342_residues
MYSFKCDYSEGCHPRILKALAESNITQEEGYGKDSHTKNAISIIKKLVQNENVDIHLISGGTQTNLISISSFLRPHEACI
CVHSGHIAGPETGSIEYTGHKVITVDSTNGKITTDKIQQVLDFHRNEHFVKPKLVYISNSTEVGTVYTKEEMRNLSEFCK
KKNLILYVDGARLGSALAVKESNLTLKDMCGFSDAFCIGGTKNGALIGEALVIKNQNLKEDFRYNIKQKGALLAKGRVLG
IQFEELFKDNLYFDLANHANEMASILTKGLKDANCEFFVESKSNQIFPILSNENIKILQERFSFNIWEKVGNKNSAIRLV
TSWATTKEVVFEFIQELKQLVE

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=325, Percent_Identity=26.1538461538462, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 38370; Mature: 38370

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSFKCDYSEGCHPRILKALAESNITQEEGYGKDSHTKNAISIIKKLVQNENVDIHLISG
CCEEECCCCCCCCHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECC
GTQTNLISISSFLRPHEACICVHSGHIAGPETGSIEYTGHKVITVDSTNGKITTDKIQQV
CCCCCEEEHHHHCCCCCEEEEEECCCCCCCCCCCEEECCEEEEEEECCCCEEEHHHHHHH
LDFHRNEHFVKPKLVYISNSTEVGTVYTKEEMRNLSEFCKKKNLILYVDGARLGSALAVK
HHHHCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEE
ESNLTLKDMCGFSDAFCIGGTKNGALIGEALVIKNQNLKEDFRYNIKQKGALLAKGRVLG
CCCCCHHHHCCCCCEEEECCCCCCCEEEEEEEEECCCCHHHHHCCHHHCCEEEECCEEEE
IQFEELFKDNLYFDLANHANEMASILTKGLKDANCEFFVESKSNQIFPILSNENIKILQE
EEHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCHHHHHH
RFSFNIWEKVGNKNSAIRLVTSWATTKEVVFEFIQELKQLVE
HHCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MYSFKCDYSEGCHPRILKALAESNITQEEGYGKDSHTKNAISIIKKLVQNENVDIHLISG
CCEEECCCCCCCCHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECC
GTQTNLISISSFLRPHEACICVHSGHIAGPETGSIEYTGHKVITVDSTNGKITTDKIQQV
CCCCCEEEHHHHCCCCCEEEEEECCCCCCCCCCCEEECCEEEEEEECCCCEEEHHHHHHH
LDFHRNEHFVKPKLVYISNSTEVGTVYTKEEMRNLSEFCKKKNLILYVDGARLGSALAVK
HHHHCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEE
ESNLTLKDMCGFSDAFCIGGTKNGALIGEALVIKNQNLKEDFRYNIKQKGALLAKGRVLG
CCCCCHHHHCCCCCEEEECCCCCCCEEEEEEEEECCCCHHHHHCCHHHCCEEEECCEEEE
IQFEELFKDNLYFDLANHANEMASILTKGLKDANCEFFVESKSNQIFPILSNENIKILQE
EEHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCHHHHHH
RFSFNIWEKVGNKNSAIRLVTSWATTKEVVFEFIQELKQLVE
HHCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]