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The map label for this gene is hadA [H]

Identifier: 226949467

GI number: 226949467

Start: 2478744

End: 2479958

Strand: Reverse

Name: hadA [H]

Synonym: CLM_2400

Alternate gene names: 226949467

Gene position: 2479958-2478744 (Counterclockwise)

Preceding gene: 226949468

Following gene: 226949466

Centisome position: 59.68

GC content: 33.74

Gene sequence:

>1215_bases
ATGACAAAAGAGGGTTTAGCTTTAGAAGGTGTAAAAGTAGTTGAATTATCAAGCTTTGTAGCGGCTCCTAGTTGTGCAAA
AGTATTAGCAGACTGGGGAGCTGACGTAATTAAAATAGAGCCAGTTCAAGGGGACAATTTAAGGGTTGTAGGTGGGGTAT
ATAATTCACCAGCAAGAGATGACGAAAATCCTATGTTTGAACTTGAAAATGGAAATAAAAGAGGCGTTGCTATAAATACT
AGAAGTGAAAAAGGTAAAGAAGTATTAGGCAAATTGCTTAAAGATGCAGATATATTTGTTACAAATGTAAGAGAAAAGGC
ATTAGAAAGAAGTGGACTATCCTATGAACAATTAAAGGATAAATATCCTTCATTAATCCATGCGCATATATTAGGATATG
GAGAAGAAGGACCACTTAAGGATAAACCTGGATTTGATTATACTGCATACTTTGCAAGGGGAGCTGTAAGCACATCTTTA
ATGGAAAAGGGAACATCACCAGCTAATACTAATGCAGGTTTTGGTGATCATTATGCTGGTATAAGTTTAGCAGCTGGTAT
ACTAGCGGCACTTCACAAAAAGACATTAACTGGAAAAGGTGACAGAGTTACAGTAAGTTTATATCATACAGCTATATTTG
GTATGGGACTAATGATTACTACAGCTCAATACGGAAATAAAATGCCATTATCAAGAAGAACTCCTAATAATCCATTAGCA
ACAACCTATAGATGCAAAGATGATAGATGGATACAATTAGCATTACTTAAATATGATGCATGGTTCCCTAAATTCTGTAA
GGAAGTAATAAATAGACCTGATTTAATAGAAGATTCAAGATTTAATAAACAATCTGAAGTAGTAAAGCATGTTGAAACTT
TTGTTGGAATATTAGAAGGAGAATTTATTAAGAAGGATTTAAAGGAGTGGGCAGATTTATTAGATAAAGCTGACTTACCC
TATGAAAAATTACAATATTGTGAAGATATATTAGAAGACGAGCAAGCATGGGCAAATGACTATTTATTCAAGACCACATA
TGACAGTGGAAATACTGGTGTATTAGTTAATTCACCTGTTAAATTTAGTGAAGCTGGAATGAGAACATATAAAGCTGCAC
CAAAGATTGGTGAAGACACTGAGGTAGTTCTAACATCATTAGGATACAGTAAAGAAGAAATAGAAGAAATGAGAAAAGAA
GAGTCAATAAAATAA

Upstream 100 bases:

>100_bases
TATTATTTAGCTGAATTTGGTACAAGTTTACCTTTTGGAAGTAAGGCAAGCTTAGCCATTTCAATATAGTAAAGTTTAAT
ATTTAAGGAGGAATGTTAAA

Downstream 100 bases:

>100_bases
ATTAATGTAAGTTTTTAGATGGAGGGTATAAAAACTTAGATCGAGAAGGGGGAGGAATATAAATGGCTGATAAGAAAGAG
GTCAAAAAGAATGCAGCAAA

Product: 3-methyl-2-oxobutanoate dehydrogenase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTKEGLALEGVKVVELSSFVAAPSCAKVLADWGADVIKIEPVQGDNLRVVGGVYNSPARDDENPMFELENGNKRGVAINT
RSEKGKEVLGKLLKDADIFVTNVREKALERSGLSYEQLKDKYPSLIHAHILGYGEEGPLKDKPGFDYTAYFARGAVSTSL
MEKGTSPANTNAGFGDHYAGISLAAGILAALHKKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGILEGEFIKKDLKEWADLLDKADLP
YEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPVKFSEAGMRTYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKE
ESIK

Sequences:

>Translated_404_residues
MTKEGLALEGVKVVELSSFVAAPSCAKVLADWGADVIKIEPVQGDNLRVVGGVYNSPARDDENPMFELENGNKRGVAINT
RSEKGKEVLGKLLKDADIFVTNVREKALERSGLSYEQLKDKYPSLIHAHILGYGEEGPLKDKPGFDYTAYFARGAVSTSL
MEKGTSPANTNAGFGDHYAGISLAAGILAALHKKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGILEGEFIKKDLKEWADLLDKADLP
YEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPVKFSEAGMRTYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKE
ESIK
>Mature_403_residues
TKEGLALEGVKVVELSSFVAAPSCAKVLADWGADVIKIEPVQGDNLRVVGGVYNSPARDDENPMFELENGNKRGVAINTR
SEKGKEVLGKLLKDADIFVTNVREKALERSGLSYEQLKDKYPSLIHAHILGYGEEGPLKDKPGFDYTAYFARGAVSTSLM
EKGTSPANTNAGFGDHYAGISLAAGILAALHKKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLAT
TYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGILEGEFIKKDLKEWADLLDKADLPY
EKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPVKFSEAGMRTYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKEE
SIK

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=394, Percent_Identity=25.3807106598985, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI300863124, Length=331, Percent_Identity=26.5861027190332, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI266456254, Length=410, Percent_Identity=25.8536585365854, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI42794625, Length=410, Percent_Identity=25.8536585365854, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI300863126, Length=392, Percent_Identity=23.7244897959184, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI266458393, Length=318, Percent_Identity=25.4716981132075, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI266458397, Length=275, Percent_Identity=28, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI266458395, Length=141, Percent_Identity=31.2056737588652, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI42822893, Length=141, Percent_Identity=29.7872340425532, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788717, Length=423, Percent_Identity=29.3144208037825, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI87082093, Length=363, Percent_Identity=24.5179063360882, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786222, Length=403, Percent_Identity=24.5657568238213, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115535051, Length=322, Percent_Identity=25.1552795031056, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564160, Length=320, Percent_Identity=25, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648431, Length=413, Percent_Identity=28.3292978208232, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24585488, Length=376, Percent_Identity=27.6595744680851, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 44921; Mature: 44790

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEGLALEGVKVVELSSFVAAPSCAKVLADWGADVIKIEPVQGDNLRVVGGVYNSPARD
CCCCCCEECCEEEEEHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCC
DENPMFELENGNKRGVAINTRSEKGKEVLGKLLKDADIFVTNVREKALERSGLSYEQLKD
CCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHCCCHHEEHHHHHHHHHHCCCCHHHHHH
KYPSLIHAHILGYGEEGPLKDKPGFDYTAYFARGAVSTSLMEKGTSPANTNAGFGDHYAG
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
ISLAAGILAALHKKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHEEEHHCCCCCCCCCCCCCCCCC
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGILEG
EEEEECCCCEEEEEEEEHHCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EFIKKDLKEWADLLDKADLPYEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCC
KFSEAGMRTYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKEESIK
CHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKEGLALEGVKVVELSSFVAAPSCAKVLADWGADVIKIEPVQGDNLRVVGGVYNSPARD
CCCCCEECCEEEEEHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCC
DENPMFELENGNKRGVAINTRSEKGKEVLGKLLKDADIFVTNVREKALERSGLSYEQLKD
CCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHCCCHHEEHHHHHHHHHHCCCCHHHHHH
KYPSLIHAHILGYGEEGPLKDKPGFDYTAYFARGAVSTSLMEKGTSPANTNAGFGDHYAG
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
ISLAAGILAALHKKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHEEEHHCCCCCCCCCCCCCCCCC
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGILEG
EEEEECCCCEEEEEEEEHHCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EFIKKDLKEWADLLDKADLPYEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCC
KFSEAGMRTYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKEESIK
CHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA