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The map label for this gene is stc [H]

Identifier: 226949258

GI number: 226949258

Start: 2235771

End: 2237861

Strand: Reverse

Name: stc [H]

Synonym: CLM_2177

Alternate gene names: 226949258

Gene position: 2237861-2235771 (Counterclockwise)

Preceding gene: 226949259

Following gene: 226949255

Centisome position: 53.86

GC content: 43.85

Gene sequence:

>2091_bases
ATGAGAAAATTATGGAGGAATCATGAAGGAATCATGAAAAAAACGATGTCTGTAGTGGCTTTGGATGCCAGAGCCGGAGA
GTTTTATGCAAAAGAAATCAATGAACTGTTTGGGGAATATGTGGAGATAGCATCCTACAATGTGAGTGACGGGTCTGCCG
TGGGAACGTTGCCAAAGGCAGATTTATTTGTGATTTCAACAGATGCATATGGTTCCGCAGAAGAGGTGGCCCGCCATGTT
CCTATAGACAGCCTTACCATGGGAATTGAAGTTTCCTACCGGTGGAGTACGTTGCAAAACCTTAGTATGATACCAAAGGG
AACCCGAGCTCTTTTTGTAAATATGACAGATACCATGGCTCGAGAGGCTATTGCACAGCTGCAACAGCTGGGGGTAAACC
ATATTCGTTTTATTCCATTTTACCCAGGTGCTGTTTTGGAAGAGCCGGTGGATATGGCTGTAACGCCAGAGGAGGAGAGA
TATGTACCTCAGAGCGTAAAGAAAGTTTTAAATATCGGACACCGTTCCTGTACCTCGGGAATGATGATCGAGATTGCCTT
GCGTATGGGACTTGAACAGTTGTTAGAGACGAAAAAATTCCAAAATTATTTCCAGGCGATGGCAACGAATAATTACAGCT
TTAATCAGATATATGCCCGCTCTAGAAGACTGGAAAGCCAATTCCATATTTTAATGGAAATATTGGATGAGGGATTGGTA
GGCGTTAATGAAAAGGGGGAGATTTTTGCATGCAATAAGAAAGCCTGCCAGATTGCAAAAATTGCGGAAAATCTTGTTAT
TGGCAGGTGCGGGGAAAAAGTATTTCCCTATATTCCCTTTTACAGTGCATTGAAGGATAAGAAAGAAATTCCGCCTAAAG
TGATTAAGCTGGGCGGCGTAAACGTAAGTATTGAAGTTATACCGGTTCTGCGGCAGAAGAAATGCATCGGTGCATTTGCT
ACCCTGCAGGAATTTAGTGAGCTGGAATCCAAACAGAATGAGTTAAGAAGCCAGCTTCTAAAAAAGGGTTATTGTGCCAA
GTATACCTTTAATGATGTAATCGGAGAATCAGATTGTATCTGCCATACAAAGGGTATTTTGAAACGGATGGCGGCTACCG
AAAGTCCAGTTTTAATTGTAGGTGAAACAGGAACGGGAAAAGAACTGCTGGCTCATGCGGTGCATTGTGCATCTAAGCGA
AGCAAAGGTCCTTTTATTGCCATTAATGTGGCAGCCATGCCGGAAAATCTTCTGGAAAGCGAGCTTTTCGGATATGAAGA
GGGCGCATTTACCGGTGCGAAAAAAGGGGGACGCCCTGGGCTATTTGAATTTGCCCATGGTGGTACCTTATTCCTCGATG
AAGTAGAAGGTATGAGCCAGGCTATGCAGGTAAAGCTTCTGAGAGTTCTGCAGGAAGGCGAAGTCATGCGTGTAGGTGGC
AGCAGAATCGTAAGCGTTGATGTTAGAATTGTTGCAGCAACCAATGAATCTTTGGAGCAGAAGGTGGAGGAAGGAAGCTT
CCGAAAGGATCTGTATTATCGTCTGAATACTTTGACGGTTGTAGTACCGCTGTTACAGGAACGGGGAGAGGATGTCTTTA
TTTTGATGGAGCATTTTAAAGAGGAGCTCCGGGGTGACTTTAAGTTATCGGAGGAAGTGAAAGACTTTCTGCGTCAGTAT
TCCTGGCCGGGAAATATCCGGGAACTGCATAACACAGTGGAATATTTTGTTTATACCGGGAAACAGGTGATTGATATGGA
TGATTTACCGCCTACTATTTTCCATGACCGGACATCCAGACCGGTGAATGTGGAGAAGAAGAAGAGACTGCGGGAGGTGG
TTTCGCCCTTCTGGTTTGTTCTGGAACAGCTTTATATAGCAGCAGAGAGAAATGAGTTTATCGGAAGGGATAAGTTGCTG
TTGAAGGCGAAGAAGCAGTATCTTCTATTGTCCCAAAAGGAGATTCGGGATATTTTAAAGGATATGGAGAAAAAAGGTTT
TGTAAAAATCGGAAAAGGAAGAGGCGGTAGCAGGATTACCTTGAAGGGGAAGGAATACTGTCAGAGTCGGGATAAGTCTT
TGGATAAGTAG

Upstream 100 bases:

>100_bases
TACATTCTTAAATGATCAAAAAGTTACATTCTAATCTAATCTTGACATTTATACAAAATTGCATTCACTTATTCTTTAAG
CTATAATAAATGTAGGTAAT

Downstream 100 bases:

>100_bases
AAAAACATATAGAAAGAAAGCAGTGCCAAGTTATAATATACTTAGCACTGCCTTTTATGAGTCTTAAATTATAGTGATAA
ATAAATTTTTTATTTATATT

Product: sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKADLFVISTDAYGSAEEVARHV
PIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMAREAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEER
YVPQSVKKVLNIGHRSCTSGMMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEIPPKVIKLGGVNVSIEVIPVLRQKKCIGAFA
TLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCICHTKGILKRMAATESPVLIVGETGTGKELLAHAVHCASKR
SKGPFIAINVAAMPENLLESELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
SRIVSVDVRIVAATNESLEQKVEEGSFRKDLYYRLNTLTVVVPLLQERGEDVFILMEHFKEELRGDFKLSEEVKDFLRQY
SWPGNIRELHNTVEYFVYTGKQVIDMDDLPPTIFHDRTSRPVNVEKKKRLREVVSPFWFVLEQLYIAAERNEFIGRDKLL
LKAKKQYLLLSQKEIRDILKDMEKKGFVKIGKGRGGSRITLKGKEYCQSRDKSLDK

Sequences:

>Translated_696_residues
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKADLFVISTDAYGSAEEVARHV
PIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMAREAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEER
YVPQSVKKVLNIGHRSCTSGMMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEIPPKVIKLGGVNVSIEVIPVLRQKKCIGAFA
TLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCICHTKGILKRMAATESPVLIVGETGTGKELLAHAVHCASKR
SKGPFIAINVAAMPENLLESELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
SRIVSVDVRIVAATNESLEQKVEEGSFRKDLYYRLNTLTVVVPLLQERGEDVFILMEHFKEELRGDFKLSEEVKDFLRQY
SWPGNIRELHNTVEYFVYTGKQVIDMDDLPPTIFHDRTSRPVNVEKKKRLREVVSPFWFVLEQLYIAAERNEFIGRDKLL
LKAKKQYLLLSQKEIRDILKDMEKKGFVKIGKGRGGSRITLKGKEYCQSRDKSLDK
>Mature_696_residues
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKADLFVISTDAYGSAEEVARHV
PIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMAREAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEER
YVPQSVKKVLNIGHRSCTSGMMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEIPPKVIKLGGVNVSIEVIPVLRQKKCIGAFA
TLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCICHTKGILKRMAATESPVLIVGETGTGKELLAHAVHCASKR
SKGPFIAINVAAMPENLLESELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
SRIVSVDVRIVAATNESLEQKVEEGSFRKDLYYRLNTLTVVVPLLQERGEDVFILMEHFKEELRGDFKLSEEVKDFLRQY
SWPGNIRELHNTVEYFVYTGKQVIDMDDLPPTIFHDRTSRPVNVEKKKRLREVVSPFWFVLEQLYIAAERNEFIGRDKLL
LKAKKQYLLLSQKEIRDILKDMEKKGFVKIGKGRGGSRITLKGKEYCQSRDKSLDK

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=278, Percent_Identity=44.2446043165468, Blast_Score=235, Evalue=6e-63,
Organism=Escherichia coli, GI1789233, Length=259, Percent_Identity=44.4015444015444, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1790299, Length=250, Percent_Identity=49.2, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1790437, Length=269, Percent_Identity=46.4684014869888, Blast_Score=220, Evalue=3e-58,
Organism=Escherichia coli, GI1786524, Length=266, Percent_Identity=44.3609022556391, Blast_Score=219, Evalue=7e-58,
Organism=Escherichia coli, GI87082117, Length=266, Percent_Identity=43.609022556391, Blast_Score=211, Evalue=2e-55,
Organism=Escherichia coli, GI87081872, Length=246, Percent_Identity=46.7479674796748, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI87082152, Length=242, Percent_Identity=45.8677685950413, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI1788905, Length=253, Percent_Identity=44.6640316205534, Blast_Score=202, Evalue=8e-53,
Organism=Escherichia coli, GI1789087, Length=257, Percent_Identity=42.4124513618677, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787583, Length=348, Percent_Identity=32.183908045977, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI87081858, Length=404, Percent_Identity=26.2376237623762, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1789828, Length=302, Percent_Identity=32.1192052980132, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 78696; Mature: 78696

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKA
CCCHHHCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DLFVISTDAYGSAEEVARHVPIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMA
CEEEEECCCCCCHHHHHHHCCCCCEEEEEEEEEEHHHHHHCCCCCCCCEEEEEECHHHHH
REAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEERYVPQSVKKVLNIGHRSCTSG
HHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCCC
MMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEIPPKVIKLGGV
CCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHEEECCC
NVSIEVIPVLRQKKCIGAFATLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCI
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCE
CHTKGILKRMAATESPVLIVGETGTGKELLAHAVHCASKRSKGPFIAINVAAMPENLLES
EHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHH
ELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
HHCCCCCCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECC
SRIVSVDVRIVAATNESLEQKVEEGSFRKDLYYRLNTLTVVVPLLQERGEDVFILMEHFK
CEEEEEEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHH
EELRGDFKLSEEVKDFLRQYSWPGNIRELHNTVEYFVYTGKQVIDMDDLPPTIFHDRTSR
HHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCEEEECCCCCCHHCCCCCCC
PVNVEKKKRLREVVSPFWFVLEQLYIAAERNEFIGRDKLLLKAKKQYLLLSQKEIRDILK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DMEKKGFVKIGKGRGGSRITLKGKEYCQSRDKSLDK
HHHHCCCEEEECCCCCCEEEECCHHHHHHHHCCCCC
>Mature Secondary Structure
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKA
CCCHHHCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DLFVISTDAYGSAEEVARHVPIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMA
CEEEEECCCCCCHHHHHHHCCCCCEEEEEEEEEEHHHHHHCCCCCCCCEEEEEECHHHHH
REAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEERYVPQSVKKVLNIGHRSCTSG
HHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCCC
MMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEIPPKVIKLGGV
CCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHEEECCC
NVSIEVIPVLRQKKCIGAFATLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCI
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCE
CHTKGILKRMAATESPVLIVGETGTGKELLAHAVHCASKRSKGPFIAINVAAMPENLLES
EHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHH
ELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
HHCCCCCCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECC
SRIVSVDVRIVAATNESLEQKVEEGSFRKDLYYRLNTLTVVVPLLQERGEDVFILMEHFK
CEEEEEEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHH
EELRGDFKLSEEVKDFLRQYSWPGNIRELHNTVEYFVYTGKQVIDMDDLPPTIFHDRTSR
HHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCEEEECCCCCCHHCCCCCCC
PVNVEKKKRLREVVSPFWFVLEQLYIAAERNEFIGRDKLLLKAKKQYLLLSQKEIRDILK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DMEKKGFVKIGKGRGGSRITLKGKEYCQSRDKSLDK
HHHHCCCEEEECCCCCCEEEECCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA