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The map label for this gene is inlA [H]

Identifier: 226949256

GI number: 226949256

Start: 2232541

End: 2233539

Strand: Direct

Name: inlA [H]

Synonym: CLM_2175

Alternate gene names: 226949256

Gene position: 2232541-2233539 (Clockwise)

Preceding gene: 226949254

Following gene: 226949257

Centisome position: 53.73

GC content: 21.72

Gene sequence:

>999_bases
GTGAAAAAGAAAAAGATTTTTTTAATGATATTTTGTCTAATTATAATTACATCTACAGTTTTAATTTATAATCACAATAA
AACTAAAGTTACTCCTACTGAGGCAAATGTACAAAAAGTTCAGTCTGAAAAAAATTCATCTCAAAACAATGTAAACAATA
ATAAAAATTCTAAAAATAATTCTGGTAATAAGGAAGCCCTTGAAGAAGATGAAAAAAATAATGATTCAGAAACTAGGGAA
ACAGAAACACCTACTATTATTAAAAACAATAATTCAAAGAACTTAGACTATGTGAAAAATTTAGATAAAATATCCTCATT
AGAAATTGTTGATAGTGCCATAGAGCGAATAGACAAATTAAAAGGAAGGGATAATATTAAAACTTTAAAAATAGTTCACT
GCAATGTAAAAGATTTAGAGATTATATCTACATTAAAGAACCTTGAGAATTTAGAAATTATAGATTGTAAGTTAAATGAT
GTATCAATAGTTAAAAACTTAAAAAACTTAAAAAGATTAGATATTAGCAATAATGAAATAAATAATTTAAACGGATTAGA
AAATCTAACAAATTTAAAAGAACTTTATATGTCAAACAATAATATAGCAGATCTAAAACCAATTCATAACTTACTTAACC
TAACCAATTTAGATATTAGTGATAATAAAATTACTAGCATTAAAGAATTAAAAAATATGAAATCCATTAAAGAACTTAAT
ATATGCAACAACAATCTATCTAATTTAGAAGGAATAGAAAATATGAGTAAAATTACAGGTCTTTGGGCTAGTAACAATAA
AATAAATAATATTTCTATACTTTCAAATAAAAATGAAATAGTAAATTTATCACTAGATAATAATAAAATATCAGACATAT
CAACTATAAGTAACTTTAGAAAATTGAAATCTCTGAAACTAGATAAAAATAATATATCAAATTATAAACCATTAAAAGAT
ATATATAAAAATCTAGTTGACCCAGATTTTTCAATATAA

Upstream 100 bases:

>100_bases
ATAATTTATATAAAGTTTCGAGAAATAATTGCAATAATAAGTAAAAATTGGTATACTAACAACAAATAGTAAAAATTTTC
CGAAAATAGAGGTGAAAAAA

Downstream 100 bases:

>100_bases
AATAAAAAAGGGGGAAAAATAATGAAAAAGAATCTTTTACCCAAATTAGTTTTACCAATTTTAGTTGCATCATCTACTAT
TATAGGGGCAAATAATACCA

Product: putative internalin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKKKKIFLMIFCLIIITSTVLIYNHNKTKVTPTEANVQKVQSEKNSSQNNVNNNKNSKNNSGNKEALEEDEKNNDSETRE
TETPTIIKNNNSKNLDYVKNLDKISSLEIVDSAIERIDKLKGRDNIKTLKIVHCNVKDLEIISTLKNLENLEIIDCKLND
VSIVKNLKNLKRLDISNNEINNLNGLENLTNLKELYMSNNNIADLKPIHNLLNLTNLDISDNKITSIKELKNMKSIKELN
ICNNNLSNLEGIENMSKITGLWASNNKINNISILSNKNEIVNLSLDNNKISDISTISNFRKLKSLKLDKNNISNYKPLKD
IYKNLVDPDFSI

Sequences:

>Translated_332_residues
MKKKKIFLMIFCLIIITSTVLIYNHNKTKVTPTEANVQKVQSEKNSSQNNVNNNKNSKNNSGNKEALEEDEKNNDSETRE
TETPTIIKNNNSKNLDYVKNLDKISSLEIVDSAIERIDKLKGRDNIKTLKIVHCNVKDLEIISTLKNLENLEIIDCKLND
VSIVKNLKNLKRLDISNNEINNLNGLENLTNLKELYMSNNNIADLKPIHNLLNLTNLDISDNKITSIKELKNMKSIKELN
ICNNNLSNLEGIENMSKITGLWASNNKINNISILSNKNEIVNLSLDNNKISDISTISNFRKLKSLKLDKNNISNYKPLKD
IYKNLVDPDFSI
>Mature_332_residues
MKKKKIFLMIFCLIIITSTVLIYNHNKTKVTPTEANVQKVQSEKNSSQNNVNNNKNSKNNSGNKEALEEDEKNNDSETRE
TETPTIIKNNNSKNLDYVKNLDKISSLEIVDSAIERIDKLKGRDNIKTLKIVHCNVKDLEIISTLKNLENLEIIDCKLND
VSIVKNLKNLKRLDISNNEINNLNGLENLTNLKELYMSNNNIADLKPIHNLLNLTNLDISDNKITSIKELKNMKSIKELN
ICNNNLSNLEGIENMSKITGLWASNNKINNISILSNKNEIVNLSLDNNKISDISTISNFRKLKSLKLDKNNISNYKPLKD
IYKNLVDPDFSI

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=230, Percent_Identity=26.5217391304348, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI21389483, Length=170, Percent_Identity=32.9411764705882, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI66472382, Length=129, Percent_Identity=32.5581395348837, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI55743114, Length=196, Percent_Identity=25, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17536161, Length=204, Percent_Identity=28.921568627451, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554124, Length=188, Percent_Identity=28.1914893617021, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17531555, Length=205, Percent_Identity=26.3414634146341, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI62472958, Length=236, Percent_Identity=30.0847457627119, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24650330, Length=236, Percent_Identity=30.0847457627119, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007092, Length=236, Percent_Identity=30.0847457627119, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650334, Length=236, Percent_Identity=30.0847457627119, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650332, Length=236, Percent_Identity=30.0847457627119, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362655, Length=236, Percent_Identity=30.0847457627119, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362657, Length=236, Percent_Identity=30.0847457627119, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281362651, Length=236, Percent_Identity=30.0847457627119, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24650336, Length=236, Percent_Identity=30.0847457627119, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281362653, Length=236, Percent_Identity=30.0847457627119, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21358617, Length=201, Percent_Identity=26.3681592039801, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 37809; Mature: 37809

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKKIFLMIFCLIIITSTVLIYNHNKTKVTPTEANVQKVQSEKNSSQNNVNNNKNSKNN
CCCCHHHHHHHHHHHHHHHEEEEECCCCEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
SGNKEALEEDEKNNDSETRETETPTIIKNNNSKNLDYVKNLDKISSLEIVDSAIERIDKL
CCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KGRDNIKTLKIVHCNVKDLEIISTLKNLENLEIIDCKLNDVSIVKNLKNLKRLDISNNEI
CCCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCC
NNLNGLENLTNLKELYMSNNNIADLKPIHNLLNLTNLDISDNKITSIKELKNMKSIKELN
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
ICNNNLSNLEGIENMSKITGLWASNNKINNISILSNKNEIVNLSLDNNKISDISTISNFR
HCCCCHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCEEEEEEECCCCCHHHHHHHHHH
KLKSLKLDKNNISNYKPLKDIYKNLVDPDFSI
HHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKKKIFLMIFCLIIITSTVLIYNHNKTKVTPTEANVQKVQSEKNSSQNNVNNNKNSKNN
CCCCHHHHHHHHHHHHHHHEEEEECCCCEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
SGNKEALEEDEKNNDSETRETETPTIIKNNNSKNLDYVKNLDKISSLEIVDSAIERIDKL
CCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KGRDNIKTLKIVHCNVKDLEIISTLKNLENLEIIDCKLNDVSIVKNLKNLKRLDISNNEI
CCCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCC
NNLNGLENLTNLKELYMSNNNIADLKPIHNLLNLTNLDISDNKITSIKELKNMKSIKELN
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
ICNNNLSNLEGIENMSKITGLWASNNKINNISILSNKNEIVNLSLDNNKISDISTISNFR
HCCCCHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCEEEEEEECCCCCHHHHHHHHHH
KLKSLKLDKNNISNYKPLKDIYKNLVDPDFSI
HHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]