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The map label for this gene is bltR [H]

Identifier: 226949253

GI number: 226949253

Start: 2229163

End: 2229984

Strand: Direct

Name: bltR [H]

Synonym: CLM_2172

Alternate gene names: 226949253

Gene position: 2229163-2229984 (Clockwise)

Preceding gene: 226949250

Following gene: 226949254

Centisome position: 53.65

GC content: 31.63

Gene sequence:

>822_bases
ATGCAAGAAAAATATTTTACTACTGGAGAATTCGCTAGAATGTGTAATGTTGAAAAACATGTTCTGTTCCATTATGATGA
CATCGGCTTATTCCGACCAGCAATCATCAAAAAAAATGGTTACCGTTACTACTCATATCATCAGTATTTTACATTCTCTG
TTATATTGAACCTAAAAAAAATTGGAATGTCTTTAAAGGACATAAAAATCTATCTTGAGCAGCGCAACCCATCCATATTC
TTAGATTTATTAGAAGAAAAAAGTAAAGAGGTAGCTGAAAAAATAAAATATTTTGAAGATATACAGGAAATGATTGAAAG
TATGAAATCCATGACCACAGAAGGTATGAATAGCCACAATAACATTTACTTGGAATACTTACCTCAGGAGACCATTCTCC
CATCGAATAATATGGAGAATTCAACAAATAAAACCTTTGCCAACTATATGCAAGAATATATTAAATTCTGTCAAGATCTG
GGGATTGCAGTTCAGGAATCTGTCGGTGGCATCATATCAGTTAGAAATTTGAGAAAGAATAAATCCACAAATCTTTCTTA
TCTGTATATTAAAACAAAATCCTTTCTACCGGGTAAAACAGTAATTCGAAAACCAGGAATCTATCTATGTGGATACTTTG
AAGGTACATACGATGACTTATGCCATGCTTATGAGAAAATGCTAAATTATGCGGATGAGAATGAAATTATTTTAGGAGAG
TACTCTTTTGAGGAATATCTAATTTCTGATATTTCCCAAAAGGAACAAAAGCATTATATTACAAAACTGATGATAGAAAC
TTTAGAAAGTGACTTAACATAG

Upstream 100 bases:

>100_bases
TTGTTAGTGATTTTTTGTAAAATCAATCCTTGATTTCCACATCAACATATATTATCATAAACTATAATGTTACCTTATAG
TCAAGAGGAGATTTTAAAAA

Downstream 100 bases:

>100_bases
TATAGGCATCTGCCATATGTTGAGTCATTTATTTCTGTACCTTTTCATTAAAGCGAAACTCTATACTATCCATATATCTA
TACATAATTCTAGAGCTAAT

Product: ABC transporter MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MQEKYFTTGEFARMCNVEKHVLFHYDDIGLFRPAIIKKNGYRYYSYHQYFTFSVILNLKKIGMSLKDIKIYLEQRNPSIF
LDLLEEKSKEVAEKIKYFEDIQEMIESMKSMTTEGMNSHNNIYLEYLPQETILPSNNMENSTNKTFANYMQEYIKFCQDL
GIAVQESVGGIISVRNLRKNKSTNLSYLYIKTKSFLPGKTVIRKPGIYLCGYFEGTYDDLCHAYEKMLNYADENEIILGE
YSFEEYLISDISQKEQKHYITKLMIETLESDLT

Sequences:

>Translated_273_residues
MQEKYFTTGEFARMCNVEKHVLFHYDDIGLFRPAIIKKNGYRYYSYHQYFTFSVILNLKKIGMSLKDIKIYLEQRNPSIF
LDLLEEKSKEVAEKIKYFEDIQEMIESMKSMTTEGMNSHNNIYLEYLPQETILPSNNMENSTNKTFANYMQEYIKFCQDL
GIAVQESVGGIISVRNLRKNKSTNLSYLYIKTKSFLPGKTVIRKPGIYLCGYFEGTYDDLCHAYEKMLNYADENEIILGE
YSFEEYLISDISQKEQKHYITKLMIETLESDLT
>Mature_273_residues
MQEKYFTTGEFARMCNVEKHVLFHYDDIGLFRPAIIKKNGYRYYSYHQYFTFSVILNLKKIGMSLKDIKIYLEQRNPSIF
LDLLEEKSKEVAEKIKYFEDIQEMIESMKSMTTEGMNSHNNIYLEYLPQETILPSNNMENSTNKTFANYMQEYIKFCQDL
GIAVQESVGGIISVRNLRKNKSTNLSYLYIKTKSFLPGKTVIRKPGIYLCGYFEGTYDDLCHAYEKMLNYADENEIILGE
YSFEEYLISDISQKEQKHYITKLMIETLESDLT

Specific function: Activates transcription of the blt gene in response to structurally dissimilar drugs [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011256
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 32191; Mature: 32191

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKYFTTGEFARMCNVEKHVLFHYDDIGLFRPAIIKKNGYRYYSYHQYFTFSVILNLKK
CCCCCCCCHHHHHHHCCCCEEEEEECCCCHHCHHHEECCCCEEEEEHHHHHHHHHHHHHH
IGMSLKDIKIYLEQRNPSIFLDLLEEKSKEVAEKIKYFEDIQEMIESMKSMTTEGMNSHN
HCCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NIYLEYLPQETILPSNNMENSTNKTFANYMQEYIKFCQDLGIAVQESVGGIISVRNLRKN
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEHHHHHCC
KSTNLSYLYIKTKSFLPGKTVIRKPGIYLCGYFEGTYDDLCHAYEKMLNYADENEIILGE
CCCCEEEEEEEECCCCCCCHHEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEC
YSFEEYLISDISQKEQKHYITKLMIETLESDLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQEKYFTTGEFARMCNVEKHVLFHYDDIGLFRPAIIKKNGYRYYSYHQYFTFSVILNLKK
CCCCCCCCHHHHHHHCCCCEEEEEECCCCHHCHHHEECCCCEEEEEHHHHHHHHHHHHHH
IGMSLKDIKIYLEQRNPSIFLDLLEEKSKEVAEKIKYFEDIQEMIESMKSMTTEGMNSHN
HCCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NIYLEYLPQETILPSNNMENSTNKTFANYMQEYIKFCQDLGIAVQESVGGIISVRNLRKN
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEHHHHHCC
KSTNLSYLYIKTKSFLPGKTVIRKPGIYLCGYFEGTYDDLCHAYEKMLNYADENEIILGE
CCCCEEEEEEEECCCCCCCHHEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEC
YSFEEYLISDISQKEQKHYITKLMIETLESDLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7608059; 8969508; 9384377 [H]