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The map label for this gene is pdxK [H]

Identifier: 226948668

GI number: 226948668

Start: 1623680

End: 1624516

Strand: Direct

Name: pdxK [H]

Synonym: CLM_1564

Alternate gene names: 226948668

Gene position: 1623680-1624516 (Clockwise)

Preceding gene: 226948667

Following gene: 226948670

Centisome position: 39.08

GC content: 28.43

Gene sequence:

>837_bases
ATGAAAGTAGATACAAAAAAAGTAGCGGCTATACATGATATATCTGGTTATGGGAGAGCATCCTTGACTACAGTAATACC
TATAATATCCCTTATGGGTATGCAGGTATGTCCAATTCCCACAGCGGTTTTGTCTACTCATACAGGGGGATTTGGTAGTC
CTGAAATAATAGATTTAACAGATAATTTACAGGCTTATATAAATCATTGGAAAAGCTTAAATTTAGATTTTAATTGCATA
TATAGTGGATATTTAGGATCAGTACATCAAATAAATATAATATCAAGTTTTATAAAGTATTTTAAGAAGAAAGATACGTT
GGTAGTTATAGATCCAGTAATGGGAGATGATTGTGAGCTTTATTCTGCTATAGATTATGAAATGGTACATAAAATGAGAG
AATTCATAAAATTAGCCCATGTTATAACGCCAAATTATACTGAAGCTTGTTATCTTTTAAATAAGGATTGTTTTAAATGT
AAAATTTCCGAAAAAGAAGTTAAAAAAATGCTTATAAGCTTAAGTGATATAGGGCCAGAAAATGTTATAATAACCAGTGT
TCCCTTATATGATAATATAATAGCTACAGTTTCATACAATAAAGCAAATGAAGAATTTTATATAGCAAAAACAGAGAAAT
TAAATGTAAATTATCCTGGTACAGGAGATGCTTTTACTAGTGTAATTGTAGGAAGTTTATTAAAAGGAGAAAGCATAAAA
ACTGCCGTAGATAAGGCTGTTGATTTTATAAAGTATGGTATAGAAATAAGTTTGAAATATGATTATAATCAAAGGGAAGG
TATTTTATTAGAAAAAGCTTTAAAAAAGTTAATATAG

Upstream 100 bases:

>100_bases
TTCAAATTAACAATTGTATGGATACAGTTGAAAAAATATCAAATTTCATATATTTTAAATATAAAATTATATAAATTGAA
ATTGTTTAGGAGATGGACAT

Downstream 100 bases:

>100_bases
AATAGAATCAAGTATTTCAGTCTTAGATAGATCTGTCTTATAAGGAGACATTTTTGTATGAATCTTAAAAAAACTATCTA
GGAAGGTGCTTAGCATTATG

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PN/PL/PM kinase; Pyridoxal kinase; Pyridoxamine kinase; Vitamin B6 kinase [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKVDTKKVAAIHDISGYGRASLTTVIPIISLMGMQVCPIPTAVLSTHTGGFGSPEIIDLTDNLQAYINHWKSLNLDFNCI
YSGYLGSVHQINIISSFIKYFKKKDTLVVIDPVMGDDCELYSAIDYEMVHKMREFIKLAHVITPNYTEACYLLNKDCFKC
KISEKEVKKMLISLSDIGPENVIITSVPLYDNIIATVSYNKANEEFYIAKTEKLNVNYPGTGDAFTSVIVGSLLKGESIK
TAVDKAVDFIKYGIEISLKYDYNQREGILLEKALKKLI

Sequences:

>Translated_278_residues
MKVDTKKVAAIHDISGYGRASLTTVIPIISLMGMQVCPIPTAVLSTHTGGFGSPEIIDLTDNLQAYINHWKSLNLDFNCI
YSGYLGSVHQINIISSFIKYFKKKDTLVVIDPVMGDDCELYSAIDYEMVHKMREFIKLAHVITPNYTEACYLLNKDCFKC
KISEKEVKKMLISLSDIGPENVIITSVPLYDNIIATVSYNKANEEFYIAKTEKLNVNYPGTGDAFTSVIVGSLLKGESIK
TAVDKAVDFIKYGIEISLKYDYNQREGILLEKALKKLI
>Mature_278_residues
MKVDTKKVAAIHDISGYGRASLTTVIPIISLMGMQVCPIPTAVLSTHTGGFGSPEIIDLTDNLQAYINHWKSLNLDFNCI
YSGYLGSVHQINIISSFIKYFKKKDTLVVIDPVMGDDCELYSAIDYEMVHKMREFIKLAHVITPNYTEACYLLNKDCFKC
KISEKEVKKMLISLSDIGPENVIITSVPLYDNIIATVSYNKANEEFYIAKTEKLNVNYPGTGDAFTSVIVGSLLKGESIK
TAVDKAVDFIKYGIEISLKYDYNQREGILLEKALKKLI

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788758, Length=256, Percent_Identity=24.609375, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31078; Mature: 31078

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDTKKVAAIHDISGYGRASLTTVIPIISLMGMQVCPIPTAVLSTHTGGFGSPEIIDLT
CCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHCCEECCCCHHHHHCCCCCCCCCEEEECH
DNLQAYINHWKSLNLDFNCIYSGYLGSVHQINIISSFIKYFKKKDTLVVIDPVMGDDCEL
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHH
YSAIDYEMVHKMREFIKLAHVITPNYTEACYLLNKDCFKCKISEKEVKKMLISLSDIGPE
HHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHCCCCC
NVIITSVPLYDNIIATVSYNKANEEFYIAKTEKLNVNYPGTGDAFTSVIVGSLLKGESIK
CEEEEECCCCCCEEEEEEECCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCHHH
TAVDKAVDFIKYGIEISLKYDYNQREGILLEKALKKLI
HHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MKVDTKKVAAIHDISGYGRASLTTVIPIISLMGMQVCPIPTAVLSTHTGGFGSPEIIDLT
CCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHCCEECCCCHHHHHCCCCCCCCCEEEECH
DNLQAYINHWKSLNLDFNCIYSGYLGSVHQINIISSFIKYFKKKDTLVVIDPVMGDDCEL
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHH
YSAIDYEMVHKMREFIKLAHVITPNYTEACYLLNKDCFKCKISEKEVKKMLISLSDIGPE
HHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHCCCCC
NVIITSVPLYDNIIATVSYNKANEEFYIAKTEKLNVNYPGTGDAFTSVIVGSLLKGESIK
CEEEEECCCCCCEEEEEEECCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCHHH
TAVDKAVDFIKYGIEISLKYDYNQREGILLEKALKKLI
HHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA