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The map label for this gene is copA [H]

Identifier: 226948571

GI number: 226948571

Start: 1518075

End: 1520510

Strand: Direct

Name: copA [H]

Synonym: CLM_1463

Alternate gene names: 226948571

Gene position: 1518075-1520510 (Clockwise)

Preceding gene: 226948570

Following gene: 226948572

Centisome position: 36.53

GC content: 31.69

Gene sequence:

>2436_bases
ATGAGGAGATTATCATTTAATATAGAAGGAATGACCTGTGCAGCTTGTGCTAAAGCTGTGGAGAGGGTTTCTAAAAAATT
AGAAGGTGTTCAAGAGGCTAATGTTAATATAGCAACAGAAAAGTTAAGTATAATTTTTGATGAAAAAAAATGTAATACTT
TAGATATAGAAAAAGCCATAGAAAAAGCAGGATACAAGGCTTTTTTAGATGGGCAGCATATGAATTTAAAGATAGAAGGA
ATGACTTGTGCAGCTTGTGCCAAAGCTGTAGAAAGAGTTTCAAGAAAGTTAGAGGGTGTTATAGAAGCCAATGTTAATAT
AGCAACAGAAAAGCTTGATATAACTTTTGATAAATCAAAAGTAAGTATAAATGATATAAAAAAAGCTATAGAAAAGGCAG
GATATAAGGCTTTAGAAGAAAAAAATATAGAAGAAGAGAAAAAGGGAAAAGAGGATGCAATAAAATCTTTGTGGAGAAGA
TTTATAATTTCTTTAGTATTTGCAGTACCTTTGCTTACTATATCTATGGGAAGTATGATGGGTCTAAAATTACCTAAAAT
TATTAATCCAATGTACAATCCTTTAAATTTTGGATTAATACAACTTATTTTAGTAATTCCAATTATATTGGTAGGAAACA
AGTTCTTTAGGGTAGGGTTTAAATCTTTAGTTAAAGGAAGCCCTAATATGGACTCTTTAATTTCTATTGGTACATCAGCA
GCTGTAGTATATGGTATTTTTGCTATATTCCAAATATCTAAAGGAAATATGCATTATGCTCATGACTTGTATTTTGAATC
TGGAGCTACTATTTTAACCTTAATAACTTTAGGAAAATATTTAGAATCCGTATCTAAAGGTAAAACTTCTGAAGCTATAA
AGAAATTGATGGCCTTAGCTCCTAAAAATGCAACTATAATAAGAGACAATAAGGAAATAATAATTCCTATAGAAGAAGTT
AAAATAAATGATATAGTTTTAGTTAAACCAGGAGAAAAGCTTCCTGTGGATGGGGAAATTATTGAAGGTTCTACAGCTAT
AGATGAATCTATGCTTACAGGAGAAAGTTTACCTGTAGAAAAACATATAGGAGATATAGCAGTAGCAGGAAGCATAAATA
AGCATGGATTAATAAAATATAAAGCTACTAAAGTTGGGAAAGATACTACTTTAGCACAAATTATAAAACTTGTAGAAGAG
GCTCAGGGTAGTAAAGCTCCTATTGCAAGGCTAGCAGATAAAATTTCCGCTTATTTTGTACCAACAGTAATAGCTTTAGC
TATAATTTCTTCTTTAGCTTGGTATGTTAGTGGAAAATCTCTAATATTTTCATTAACTATATTTATTTCTGTATTGGTAA
TAGCTTGTCCGTGTGCTTTAGGATTAGCAACACCAACAGCTATTATGGTAGGCACAGGAAAAGGAGCAGAAAATGGGGTT
CTTATAAAAAGTGGAGGAGCTTTAGAAACTGCTCATAAAGTTCAAAGTATTATATTCGATAAAACAGGAACTATTACAGA
AGGAAAACCAAAAGTAACAGATATTTTGGTTTCCGAAGGAGTAGATGAAAAATATTTACTTCAAGTAGCAGCTACTGCAG
AAAAGGGTTCAGAACATCCTTTAGGTGAAGCTATAGTAAAAAAAGCAGAAGAAGAAAATTTAGAATTATTTCAAGGTAAA
GATTTTAGAGCAATACCTGGTAAAGGCATAGAGGTTATTATAGAGGATAAAAAAGTGCTTCTTGGAAATTTAAGACTTAT
GGAAGAATATGAGGTAGAAATAAAGGATTTTATGGATAAATCTCATAAACTTTCAAAGGAAGGTAAGACCCCAATGTTTA
TAGCCATAGAAAATAAAATTAAAGGAATAATAGCTGTAGCAGACACTCTTAAGGAAAATAGTAAAAAATCTATAGAGAAG
CTTCATAATATGGGTGTGGAAGTAGTTATGATAACTGGAGATAACAAAAATACCGCAGAGGCTATAGGAAAACAAGTAGG
TATAGATAAGATTTTTGCAGAAGTTCTTCCTAGTGATAAGGCTAACTGGGTAAAAAAACTTCAACAAGAAGGAAAAATTA
TAGCTATGGTAGGAGATGGAATTAATGATGCTCCAGCGTTAGCACAAGCAGATATTGGTATAGCCATAGGATCTGGAACA
GATGTGGCCATAGAATCTGCAGATATCGTGCTTATAAAAAGTGATTTAATGGATGTACCAACAGCTCTTAAGTTAAGTAG
AGCTACTATAAAAAATATTAAAGAAAACCTATTTTGGGCTTTTGGGTACAATACTTTGGGGATTCCAGTAGCTATGGGTG
TTTTATATATTTTTGGAGGACCGCTTTTAAATCCAATGATTGCAGCAGCGGCTATGAGTTTTAGTTCAGTTTCAGTACTT
TTAAATGCCTTAAGATTAAGAAGATTTAAATCTTAA

Upstream 100 bases:

>100_bases
CGATAACGGAGAAGAAAAGGTAGATGAAATTATAGATACATTAACTAAATTGCTTGGCAAATAGTAAATTTTAAATATCA
ACTTAAAGGTGGTGTAAAAA

Downstream 100 bases:

>100_bases
TATAAGTAAAATATAATAGTGATTACTTTTAATTTATTTGAGAAAGTTTAAAACTCAAATAGGCCTAAGTAAACAAAATT
ATATAAAATAAATTTTATTA

Product: copper-exporting ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 811

Protein sequence:

>811_residues
MRRLSFNIEGMTCAACAKAVERVSKKLEGVQEANVNIATEKLSIIFDEKKCNTLDIEKAIEKAGYKAFLDGQHMNLKIEG
MTCAACAKAVERVSRKLEGVIEANVNIATEKLDITFDKSKVSINDIKKAIEKAGYKALEEKNIEEEKKGKEDAIKSLWRR
FIISLVFAVPLLTISMGSMMGLKLPKIINPMYNPLNFGLIQLILVIPIILVGNKFFRVGFKSLVKGSPNMDSLISIGTSA
AVVYGIFAIFQISKGNMHYAHDLYFESGATILTLITLGKYLESVSKGKTSEAIKKLMALAPKNATIIRDNKEIIIPIEEV
KINDIVLVKPGEKLPVDGEIIEGSTAIDESMLTGESLPVEKHIGDIAVAGSINKHGLIKYKATKVGKDTTLAQIIKLVEE
AQGSKAPIARLADKISAYFVPTVIALAIISSLAWYVSGKSLIFSLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGV
LIKSGGALETAHKVQSIIFDKTGTITEGKPKVTDILVSEGVDEKYLLQVAATAEKGSEHPLGEAIVKKAEEENLELFQGK
DFRAIPGKGIEVIIEDKKVLLGNLRLMEEYEVEIKDFMDKSHKLSKEGKTPMFIAIENKIKGIIAVADTLKENSKKSIEK
LHNMGVEVVMITGDNKNTAEAIGKQVGIDKIFAEVLPSDKANWVKKLQQEGKIIAMVGDGINDAPALAQADIGIAIGSGT
DVAIESADIVLIKSDLMDVPTALKLSRATIKNIKENLFWAFGYNTLGIPVAMGVLYIFGGPLLNPMIAAAAMSFSSVSVL
LNALRLRRFKS

Sequences:

>Translated_811_residues
MRRLSFNIEGMTCAACAKAVERVSKKLEGVQEANVNIATEKLSIIFDEKKCNTLDIEKAIEKAGYKAFLDGQHMNLKIEG
MTCAACAKAVERVSRKLEGVIEANVNIATEKLDITFDKSKVSINDIKKAIEKAGYKALEEKNIEEEKKGKEDAIKSLWRR
FIISLVFAVPLLTISMGSMMGLKLPKIINPMYNPLNFGLIQLILVIPIILVGNKFFRVGFKSLVKGSPNMDSLISIGTSA
AVVYGIFAIFQISKGNMHYAHDLYFESGATILTLITLGKYLESVSKGKTSEAIKKLMALAPKNATIIRDNKEIIIPIEEV
KINDIVLVKPGEKLPVDGEIIEGSTAIDESMLTGESLPVEKHIGDIAVAGSINKHGLIKYKATKVGKDTTLAQIIKLVEE
AQGSKAPIARLADKISAYFVPTVIALAIISSLAWYVSGKSLIFSLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGV
LIKSGGALETAHKVQSIIFDKTGTITEGKPKVTDILVSEGVDEKYLLQVAATAEKGSEHPLGEAIVKKAEEENLELFQGK
DFRAIPGKGIEVIIEDKKVLLGNLRLMEEYEVEIKDFMDKSHKLSKEGKTPMFIAIENKIKGIIAVADTLKENSKKSIEK
LHNMGVEVVMITGDNKNTAEAIGKQVGIDKIFAEVLPSDKANWVKKLQQEGKIIAMVGDGINDAPALAQADIGIAIGSGT
DVAIESADIVLIKSDLMDVPTALKLSRATIKNIKENLFWAFGYNTLGIPVAMGVLYIFGGPLLNPMIAAAAMSFSSVSVL
LNALRLRRFKS
>Mature_811_residues
MRRLSFNIEGMTCAACAKAVERVSKKLEGVQEANVNIATEKLSIIFDEKKCNTLDIEKAIEKAGYKAFLDGQHMNLKIEG
MTCAACAKAVERVSRKLEGVIEANVNIATEKLDITFDKSKVSINDIKKAIEKAGYKALEEKNIEEEKKGKEDAIKSLWRR
FIISLVFAVPLLTISMGSMMGLKLPKIINPMYNPLNFGLIQLILVIPIILVGNKFFRVGFKSLVKGSPNMDSLISIGTSA
AVVYGIFAIFQISKGNMHYAHDLYFESGATILTLITLGKYLESVSKGKTSEAIKKLMALAPKNATIIRDNKEIIIPIEEV
KINDIVLVKPGEKLPVDGEIIEGSTAIDESMLTGESLPVEKHIGDIAVAGSINKHGLIKYKATKVGKDTTLAQIIKLVEE
AQGSKAPIARLADKISAYFVPTVIALAIISSLAWYVSGKSLIFSLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGV
LIKSGGALETAHKVQSIIFDKTGTITEGKPKVTDILVSEGVDEKYLLQVAATAEKGSEHPLGEAIVKKAEEENLELFQGK
DFRAIPGKGIEVIIEDKKVLLGNLRLMEEYEVEIKDFMDKSHKLSKEGKTPMFIAIENKIKGIIAVADTLKENSKKSIEK
LHNMGVEVVMITGDNKNTAEAIGKQVGIDKIFAEVLPSDKANWVKKLQQEGKIIAMVGDGINDAPALAQADIGIAIGSGT
DVAIESADIVLIKSDLMDVPTALKLSRATIKNIKENLFWAFGYNTLGIPVAMGVLYIFGGPLLNPMIAAAAMSFSSVSVL
LNALRLRRFKS

Specific function: Involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=863, Percent_Identity=40.2085747392816, Blast_Score=576, Evalue=1e-164,
Organism=Homo sapiens, GI115529486, Length=903, Percent_Identity=37.7630121816168, Blast_Score=549, Evalue=1e-156,
Organism=Homo sapiens, GI55743073, Length=543, Percent_Identity=44.7513812154696, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI28373107, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI28373105, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI28373113, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI28373103, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI28373115, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI28373111, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI28373109, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI27886529, Length=216, Percent_Identity=31.4814814814815, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI10835220, Length=216, Percent_Identity=31.4814814814815, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI4502285, Length=227, Percent_Identity=30.3964757709251, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI209413709, Length=227, Percent_Identity=30.3964757709251, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI24638454, Length=227, Percent_Identity=30.3964757709251, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI310128958, Length=210, Percent_Identity=31.9047619047619, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI48762685, Length=190, Percent_Identity=30.5263157894737, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI153946397, Length=240, Percent_Identity=26.6666666666667, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI118498343, Length=172, Percent_Identity=34.3023255813954, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI48762689, Length=190, Percent_Identity=29.4736842105263, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI48762691, Length=190, Percent_Identity=29.4736842105263, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI48762687, Length=190, Percent_Identity=29.4736842105263, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI51944966, Length=295, Percent_Identity=26.7796610169492, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI22748667, Length=379, Percent_Identity=24.0105540897098, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4502271, Length=240, Percent_Identity=25.4166666666667, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI237681111, Length=362, Percent_Identity=24.585635359116, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI237681109, Length=362, Percent_Identity=24.585635359116, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI21361181, Length=362, Percent_Identity=24.585635359116, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI83700225, Length=344, Percent_Identity=22.9651162790698, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI297374799, Length=344, Percent_Identity=22.6744186046512, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI1786691, Length=850, Percent_Identity=38.7058823529412, Blast_Score=566, Evalue=1e-162,
Organism=Escherichia coli, GI1789879, Length=751, Percent_Identity=33.288948069241, Blast_Score=350, Evalue=2e-97,
Organism=Escherichia coli, GI1786914, Length=452, Percent_Identity=34.2920353982301, Blast_Score=203, Evalue=4e-53,
Organism=Escherichia coli, GI2367363, Length=602, Percent_Identity=22.4252491694352, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17556548, Length=880, Percent_Identity=36.4772727272727, Blast_Score=479, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI193210130, Length=322, Percent_Identity=27.9503105590062, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71988506, Length=227, Percent_Identity=32.5991189427313, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17554158, Length=227, Percent_Identity=32.5991189427313, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17557486, Length=215, Percent_Identity=27.4418604651163, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32566766, Length=215, Percent_Identity=26.9767441860465, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997262, Length=190, Percent_Identity=31.0526315789474, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997275, Length=190, Percent_Identity=31.0526315789474, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17557770, Length=215, Percent_Identity=26.9767441860465, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193203356, Length=225, Percent_Identity=25.7777777777778, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI193203354, Length=225, Percent_Identity=25.7777777777778, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71997269, Length=172, Percent_Identity=33.7209302325581, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559224, Length=325, Percent_Identity=23.3846153846154, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17541776, Length=204, Percent_Identity=28.4313725490196, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17531459, Length=119, Percent_Identity=36.9747899159664, Blast_Score=79, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6320475, Length=869, Percent_Identity=33.9470655926352, Blast_Score=434, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6319772, Length=674, Percent_Identity=28.0415430267062, Blast_Score=288, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6321430, Length=527, Percent_Identity=26.3757115749526, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6325221, Length=528, Percent_Identity=27.2727272727273, Blast_Score=157, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6321271, Length=650, Percent_Identity=24.7692307692308, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321432, Length=169, Percent_Identity=31.3609467455621, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320245, Length=317, Percent_Identity=24.6056782334385, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320243, Length=311, Percent_Identity=24.4372990353698, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320244, Length=311, Percent_Identity=24.4372990353698, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI221329854, Length=631, Percent_Identity=35.1822503961965, Blast_Score=345, Evalue=7e-95,
Organism=Drosophila melanogaster, GI17136664, Length=216, Percent_Identity=30.0925925925926, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24762455, Length=216, Percent_Identity=30.0925925925926, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24762453, Length=216, Percent_Identity=30.0925925925926, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24762447, Length=216, Percent_Identity=30.0925925925926, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24762457, Length=216, Percent_Identity=30.0925925925926, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24762449, Length=216, Percent_Identity=30.0925925925926, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24762445, Length=216, Percent_Identity=30.0925925925926, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24762451, Length=216, Percent_Identity=30.0925925925926, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24668704, Length=192, Percent_Identity=31.7708333333333, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24668708, Length=192, Percent_Identity=31.7708333333333, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI281366617, Length=192, Percent_Identity=31.7708333333333, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24668696, Length=203, Percent_Identity=31.5270935960591, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161085803, Length=203, Percent_Identity=31.5270935960591, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281366676, Length=248, Percent_Identity=25, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45553437, Length=268, Percent_Identity=24.2537313432836, Blast_Score=77, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281362164, Length=268, Percent_Identity=24.2537313432836, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45553435, Length=270, Percent_Identity=23.7037037037037, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45553439, Length=270, Percent_Identity=23.7037037037037, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45553441, Length=268, Percent_Identity=23.8805970149254, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648580, Length=268, Percent_Identity=23.8805970149254, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648578, Length=268, Percent_Identity=23.8805970149254, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648576, Length=268, Percent_Identity=23.8805970149254, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648582, Length=227, Percent_Identity=25.1101321585903, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 87729; Mature: 87729

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00154 ATPASE_E1_E2 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLSFNIEGMTCAACAKAVERVSKKLEGVQEANVNIATEKLSIIFDEKKCNTLDIEKAI
CCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEEEEEEECCCCCEECHHHHH
EKAGYKAFLDGQHMNLKIEGMTCAACAKAVERVSRKLEGVIEANVNIATEKLDITFDKSK
HHCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCC
VSINDIKKAIEKAGYKALEEKNIEEEKKGKEDAIKSLWRRFIISLVFAVPLLTISMGSMM
CCHHHHHHHHHHHCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLKLPKIINPMYNPLNFGLIQLILVIPIILVGNKFFRVGFKSLVKGSPNMDSLISIGTSA
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHCCCHH
AVVYGIFAIFQISKGNMHYAHDLYFESGATILTLITLGKYLESVSKGKTSEAIKKLMALA
HHHHHHHHHHEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
PKNATIIRDNKEIIIPIEEVKINDIVLVKPGEKLPVDGEIIEGSTAIDESMLTGESLPVE
CCCCEEEECCCEEEEEEHEEEECCEEEECCCCCCCCCCEEECCCCHHHHHHHCCCCCCHH
KHIGDIAVAGSINKHGLIKYKATKVGKDTTLAQIIKLVEEAQGSKAPIARLADKISAYFV
HHCCCEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
PTVIALAIISSLAWYVSGKSLIFSLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCE
LIKSGGALETAHKVQSIIFDKTGTITEGKPKVTDILVSEGVDEKYLLQVAATAEKGSEHP
EEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
LGEAIVKKAEEENLELFQGKDFRAIPGKGIEVIIEDKKVLLGNLRLMEEYEVEIKDFMDK
HHHHHHHHCCCCCCCEECCCCCCCCCCCCCEEEEECCCEEHHHHHHHHHHHHHHHHHHHH
SHKLSKEGKTPMFIAIENKIKGIIAVADTLKENSKKSIEKLHNMGVEVVMITGDNKNTAE
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCHHH
AIGKQVGIDKIFAEVLPSDKANWVKKLQQEGKIIAMVGDGINDAPALAQADIGIAIGSGT
HHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCEEEECCCC
DVAIESADIVLIKSDLMDVPTALKLSRATIKNIKENLFWAFGYNTLGIPVAMGVLYIFGG
CEEEECCCEEEEECCHHCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCC
PLLNPMIAAAAMSFSSVSVLLNALRLRRFKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRLSFNIEGMTCAACAKAVERVSKKLEGVQEANVNIATEKLSIIFDEKKCNTLDIEKAI
CCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEEEEEEECCCCCEECHHHHH
EKAGYKAFLDGQHMNLKIEGMTCAACAKAVERVSRKLEGVIEANVNIATEKLDITFDKSK
HHCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCC
VSINDIKKAIEKAGYKALEEKNIEEEKKGKEDAIKSLWRRFIISLVFAVPLLTISMGSMM
CCHHHHHHHHHHHCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLKLPKIINPMYNPLNFGLIQLILVIPIILVGNKFFRVGFKSLVKGSPNMDSLISIGTSA
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHCCCHH
AVVYGIFAIFQISKGNMHYAHDLYFESGATILTLITLGKYLESVSKGKTSEAIKKLMALA
HHHHHHHHHHEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
PKNATIIRDNKEIIIPIEEVKINDIVLVKPGEKLPVDGEIIEGSTAIDESMLTGESLPVE
CCCCEEEECCCEEEEEEHEEEECCEEEECCCCCCCCCCEEECCCCHHHHHHHCCCCCCHH
KHIGDIAVAGSINKHGLIKYKATKVGKDTTLAQIIKLVEEAQGSKAPIARLADKISAYFV
HHCCCEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
PTVIALAIISSLAWYVSGKSLIFSLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCE
LIKSGGALETAHKVQSIIFDKTGTITEGKPKVTDILVSEGVDEKYLLQVAATAEKGSEHP
EEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
LGEAIVKKAEEENLELFQGKDFRAIPGKGIEVIIEDKKVLLGNLRLMEEYEVEIKDFMDK
HHHHHHHHCCCCCCCEECCCCCCCCCCCCCEEEEECCCEEHHHHHHHHHHHHHHHHHHHH
SHKLSKEGKTPMFIAIENKIKGIIAVADTLKENSKKSIEKLHNMGVEVVMITGDNKNTAE
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCHHH
AIGKQVGIDKIFAEVLPSDKANWVKKLQQEGKIIAMVGDGINDAPALAQADIGIAIGSGT
HHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCEEEECCCC
DVAIESADIVLIKSDLMDVPTALKLSRATIKNIKENLFWAFGYNTLGIPVAMGVLYIFGG
CEEEECCCEEEEECCHHCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCC
PLLNPMIAAAAMSFSSVSVLLNALRLRRFKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA