Click here to switch to the map view.

The map label for this gene is grdB [H]

Identifier: 226948525

GI number: 226948525

Start: 1471349

End: 1472650

Strand: Direct

Name: grdB [H]

Synonym: CLM_1416

Alternate gene names: 226948525

Gene position: 1471349-1472650 (Clockwise)

Preceding gene: 226948524

Following gene: 226948526

Centisome position: 35.41

GC content: 33.03

Gene sequence:

>1302_bases
ATGATTAAAGTAGTTCATTATATAAATCAGTTTTATGCGGGTATTGGAGGAGAAGACAAAGCGGATTATAAACCAGAAGT
AAGAGAGGAACCTGTAGGTCCAGGAACACAACTTAATTCTTTATTTAAAGGTGAAGCTGAAATAGTTGCTACGGTTATTT
GTGGAGATTCATATTTTAATGAAAATATAGATGAAGCTAAAAACACTATTTTAGAAATGGTTAAAAAATATGATGCGGAT
TTGTTTATAGCAGGACCTGCTTTTAATGCCGGAAGATACGGAGTGGCTTGTGGAACTATTGCAAAGGAAGTAGAGGAAAA
ATTAAATATAAAGGTTTTAACAGCTATGTATGAAGAAAATCCAGGAGTAGATTTGTATAAAAAATCTTTATATATTCTTA
AAACCAAGAAAAGTGCAGTAGGTATGAGAAAAGCATTACCTGTTATGGCAAAACTTGCATTAAAAATGGGAAAAGGGGAA
GAGATAGGACTTCCTGAAGAAGAAGGATATATAGAGAGAGGCATAAGAAAAAATTACTTTAGTGATGAAAGGGGATCTAA
AAGAGCAGTAAATCTTCTTGTAAAAAAATTAAAAGGCGAAGAATTTGTTACAGAGTTTAAAATGCCGGTTTTTGATAGGG
TAGAACCTAATAAAGCTGTAGAGGATATATCAAAATGTAAAATTGCTATTGTAACTTCTGGTGGAATAGTACCAAAGGGA
AATCCAGATCATATAGAATCCTCTAGTGCATCAAAATATGGTAAATATGATATAGAAGGACTTATGGATTTAAATTCAGA
AACTCATGAAACTGCACATGGAGGATATGATCCTAATTATGCAAATGAAGATTCAGATAGAGTTATACCTGTAGATGTAT
TAAGAAAAATGGAGAAGGAAGGGAAAATAGGATCTCTTCATAGATATTTCTATAGTACTGTTGGAAATGGTACAGCAGTG
GCATCTTCTAAAAAGTTTGGAAATGAAATAGTAAATCAGTTAAAGGAAGATGGTGTTGATGCAGTTATATTAACTTCCAC
ATGAGGAACTTGTACTCGTTGCGGTGCAACACTAGTAAAAGAAATAGAACGTGGAGGACTTCCAGTTGTGCATATGTGTA
CAGTAGTTCCAATTTCTCTTACAGTTGGTGCTAATAGAATAGTTCCAACTATAGCAATACCTCATCCACTTGGAAATCCA
AATTTAGATAAAGATAGAGAATATGAATTGAGATATAAGCTTGTAGAGAAAGCATTAAAGGCGTTAGAAACAGAAATAGA
TGAACAGAAAGTCTTTGAATAG

Upstream 100 bases:

>100_bases
AGATTCAAGTTATTACAGGAGCTACTAGTGAAGTTGGCTTTAACTATTTAAGTGCTAAAGGCTATTAAATTGTAGTTATA
TAATCAAGGGGGGAAAATAA

Downstream 100 bases:

>100_bases
AAGTTTTAATAAAGATAATTTTTAATAAATTTTATATAATTCAAAGATGATTTAATAGGTCTTAAATAGTTTCACGTGTT
AATTTTATTTAAATAATTAG

Product: glycine reductase, selenoprotein B

Products: NA

Alternate protein names: Selenoprotein PB gamma [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIKVVHYINQFYAGIGGEDKADYKPEVREEPVGPGTQLNSLFKGEAEIVATVICGDSYFNENIDEAKNTILEMVKKYDAD
LFIAGPAFNAGRYGVACGTIAKEVEEKLNIKVLTAMYEENPGVDLYKKSLYILKTKKSAVGMRKALPVMAKLALKMGKGE
EIGLPEEEGYIERGIRKNYFSDERGSKRAVNLLVKKLKGEEFVTEFKMPVFDRVEPNKAVEDISKCKIAIVTSGGIVPKG
NPDHIESSSASKYGKYDIEGLMDLNSETHETAHGGYDPNYANEDSDRVIPVDVLRKMEKEGKIGSLHRYFYSTVGNGTAV
ASSKKFGNEIVNQLKEDGVDAVILTSTUGTCTRCGATLVKEIERGGLPVVHMCTVVPISLTVGANRIVPTIAIPHPLGNP
NLDKDREYELRYKLVEKALKALETEIDEQKVFE

Sequences:

>Translated_433_residues
MIKVVHYINQFYAGIGGEDKADYKPEVREEPVGPGTQLNSLFKGEAEIVATVICGDSYFNENIDEAKNTILEMVKKYDAD
LFIAGPAFNAGRYGVACGTIAKEVEEKLNIKVLTAMYEENPGVDLYKKSLYILKTKKSAVGMRKALPVMAKLALKMGKGE
EIGLPEEEGYIERGIRKNYFSDERGSKRAVNLLVKKLKGEEFVTEFKMPVFDRVEPNKAVEDISKCKIAIVTSGGIVPKG
NPDHIESSSASKYGKYDIEGLMDLNSETHETAHGGYDPNYANEDSDRVIPVDVLRKMEKEGKIGSLHRYFYSTVGNGTAV
ASSKKFGNEIVNQLKEDGVDAVILTST*GTCTRCGATLVKEIERGGLPVVHMCTVVPISLTVGANRIVPTIAIPHPLGNP
NLDKDREYELRYKLVEKALKALETEIDEQKVFE
>Mature_433_residues
MIKVVHYINQFYAGIGGEDKADYKPEVREEPVGPGTQLNSLFKGEAEIVATVICGDSYFNENIDEAKNTILEMVKKYDAD
LFIAGPAFNAGRYGVACGTIAKEVEEKLNIKVLTAMYEENPGVDLYKKSLYILKTKKSAVGMRKALPVMAKLALKMGKGE
EIGLPEEEGYIERGIRKNYFSDERGSKRAVNLLVKKLKGEEFVTEFKMPVFDRVEPNKAVEDISKCKIAIVTSGGIVPKG
NPDHIESSSASKYGKYDIEGLMDLNSETHETAHGGYDPNYANEDSDRVIPVDVLRKMEKEGKIGSLHRYFYSTVGNGTAV
ASSKKFGNEIVNQLKEDGVDAVILTST*GTCTRCGATLVKEIERGGLPVVHMCTVVPISLTVGANRIVPTIAIPHPLGNP
NLDKDREYELRYKLVEKALKALETEIDEQKVFE

Specific function: In the first step of glycine reductase, the substrate is bound to component PB via a Schiff base intermediate. Then the PB- activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated seleno

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grdB/grdF/grdH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010186
- InterPro:   IPR022787
- InterPro:   IPR010187 [H]

Pfam domain/function: PF07355 GRDB [H]

EC number: =1.21.4.2 [H]

Molecular weight: Translated: 47627; Mature: 47627

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVVHYINQFYAGIGGEDKADYKPEVREEPVGPGTQLNSLFKGEAEIVATVICGDSYFN
CCHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCHHHHHHHCCCCCEEEEEEECCHHHC
ENIDEAKNTILEMVKKYDADLFIAGPAFNAGRYGVACGTIAKEVEEKLNIKVLTAMYEEN
CCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEHHCC
PGVDLYKKSLYILKTKKSAVGMRKALPVMAKLALKMGKGEEIGLPEEEGYIERGIRKNYF
CCCCEECCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
SDERGSKRAVNLLVKKLKGEEFVTEFKMPVFDRVEPNKAVEDISKCKIAIVTSGGIVPKG
CCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHCCCCCHHHHHHHHHCEEEEEECCCCCCCC
NPDHIESSSASKYGKYDIEGLMDLNSETHETAHGGYDPNYANEDSDRVIPVDVLRKMEKE
CCCCCCCCCCCCCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCEECHHHHHHHHHC
GKIGSLHRYFYSTVGNGTAVASSKKFGNEIVNQLKEDGVDAVILTSTGTCTRCGATLVKE
CCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHH
IERGGLPVVHMCTVVPISLTVGANRIVPTIAIPHPLGNPNLDKDREYELRYKLVEKALKA
HHHCCCCEEEHHHHEEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LETEIDEQKVFE
HHHHCCHHHCCC
>Mature Secondary Structure
MIKVVHYINQFYAGIGGEDKADYKPEVREEPVGPGTQLNSLFKGEAEIVATVICGDSYFN
CCHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCHHHHHHHCCCCCEEEEEEECCHHHC
ENIDEAKNTILEMVKKYDADLFIAGPAFNAGRYGVACGTIAKEVEEKLNIKVLTAMYEEN
CCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEHHCC
PGVDLYKKSLYILKTKKSAVGMRKALPVMAKLALKMGKGEEIGLPEEEGYIERGIRKNYF
CCCCEECCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
SDERGSKRAVNLLVKKLKGEEFVTEFKMPVFDRVEPNKAVEDISKCKIAIVTSGGIVPKG
CCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHCCCCCHHHHHHHHHCEEEEEECCCCCCCC
NPDHIESSSASKYGKYDIEGLMDLNSETHETAHGGYDPNYANEDSDRVIPVDVLRKMEKE
CCCCCCCCCCCCCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCEECHHHHHHHHHC
GKIGSLHRYFYSTVGNGTAVASSKKFGNEIVNQLKEDGVDAVILTSTGTCTRCGATLVKE
CCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHH
IERGGLPVVHMCTVVPISLTVGANRIVPTIAIPHPLGNPNLDKDREYELRYKLVEKALKA
HHHCCCCEEEHHHHEEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LETEIDEQKVFE
HHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA