Definition Clostridium botulinum A2 str. Kyoto chromosome, complete genome.
Accession NC_012563
Length 4,155,278

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The map label for this gene is yhcG [H]

Identifier: 226947811

GI number: 226947811

Start: 717523

End: 718218

Strand: Direct

Name: yhcG [H]

Synonym: CLM_0662

Alternate gene names: 226947811

Gene position: 717523-718218 (Clockwise)

Preceding gene: 226947810

Following gene: 226947812

Centisome position: 17.27

GC content: 28.88

Gene sequence:

>696_bases
ATGGATAAGATATTAACTTGTTCTAATTTAAAGAAAGGTTATTTTAATAAAAATGCATTAAACGGACTTGCAATGGAAGT
AAAAAAGGGAAGAATAGTAGGATTATTAGGACCTAACGGTAGCGGGAAAACCACATTTTTAAAAATAGCAGCAGGAATAT
TAAGATATAGTTCAGGAGAGATATTAATAGATGGAGAAGCTCCAGGAGTGAACACAAAGGCTAAAGTTGCATATTTACCA
GATAAAAATTTTTTGTATAAATGGATGAAAATAAAGGATGCCATAGAGTTTTATAAAGATTTTTATAAAGATTTTGACGA
GAAAAAATGTAATGAGCTTTTACAATTTATGAATTTAGATAAAGACAGTAAGGTTACTTCACTATCTAAAGGAATGCTTG
AAAAATTACTTCTTACATTAACTTTATCTAGAAAAGCAAAATTATATTTATTAGATGAACCCTTAGGTGGAGTGGACCCA
GTAAGCAGAGATAAAATACTAGATGCTATAGTAAATAATTATAGTGAAGATAGCACCATTATAGTTACTACTCATTTAGT
TAACGATATAGAAAGAATTTTTGATGATGTTTTCTTTATATCTGAGGGAGAGATAGCATTAAGCGGTATAGCAGAAGAAC
TTAGAATGGAAAAAGGAATGTCTATAGATGAATTATATAAGGAGGTATTTCAATAA

Upstream 100 bases:

>100_bases
ATAGTACAAAATTTTTTAGAGGGAATGAAGAAAATAGGTTTTAAAAAAGAAGAAATATTAAATTTAGTAAGAAGAGAATT
AGAAAGGGAGGATATAAATA

Downstream 100 bases:

>100_bases
TGGGTAAACTTATAAAATATAATTTGAAATGTTATTATAAAGAAATATTAATATTATTAAGTTTAATAGTTTTATCTAAT
TTAGCTCTCTTTTATAAAAT

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MDKILTCSNLKKGYFNKNALNGLAMEVKKGRIVGLLGPNGSGKTTFLKIAAGILRYSSGEILIDGEAPGVNTKAKVAYLP
DKNFLYKWMKIKDAIEFYKDFYKDFDEKKCNELLQFMNLDKDSKVTSLSKGMLEKLLLTLTLSRKAKLYLLDEPLGGVDP
VSRDKILDAIVNNYSEDSTIIVTTHLVNDIERIFDDVFFISEGEIALSGIAEELRMEKGMSIDELYKEVFQ

Sequences:

>Translated_231_residues
MDKILTCSNLKKGYFNKNALNGLAMEVKKGRIVGLLGPNGSGKTTFLKIAAGILRYSSGEILIDGEAPGVNTKAKVAYLP
DKNFLYKWMKIKDAIEFYKDFYKDFDEKKCNELLQFMNLDKDSKVTSLSKGMLEKLLLTLTLSRKAKLYLLDEPLGGVDP
VSRDKILDAIVNNYSEDSTIIVTTHLVNDIERIFDDVFFISEGEIALSGIAEELRMEKGMSIDELYKEVFQ
>Mature_231_residues
MDKILTCSNLKKGYFNKNALNGLAMEVKKGRIVGLLGPNGSGKTTFLKIAAGILRYSSGEILIDGEAPGVNTKAKVAYLP
DKNFLYKWMKIKDAIEFYKDFYKDFDEKKCNELLQFMNLDKDSKVTSLSKGMLEKLLLTLTLSRKAKLYLLDEPLGGVDP
VSRDKILDAIVNNYSEDSTIIVTTHLVNDIERIFDDVFFISEGEIALSGIAEELRMEKGMSIDELYKEVFQ

Specific function: Unknown

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI21536376, Length=227, Percent_Identity=31.2775330396476, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI116734710, Length=219, Percent_Identity=28.310502283105, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI6005701, Length=219, Percent_Identity=28.7671232876712, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI153792144, Length=266, Percent_Identity=25.9398496240602, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI105990541, Length=201, Percent_Identity=28.8557213930348, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI27881501, Length=210, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI45446740, Length=201, Percent_Identity=28.3582089552239, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI47078218, Length=201, Percent_Identity=28.3582089552239, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI30795238, Length=210, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI27436953, Length=221, Percent_Identity=27.1493212669683, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI150417984, Length=209, Percent_Identity=30.1435406698565, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI27477115, Length=226, Percent_Identity=27.4336283185841, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI31657092, Length=204, Percent_Identity=27.4509803921569, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI27262624, Length=214, Percent_Identity=27.1028037383178, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI27262626, Length=214, Percent_Identity=27.1028037383178, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI89111135, Length=216, Percent_Identity=23.6111111111111, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI66529005, Length=227, Percent_Identity=24.6696035242291, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI215820660, Length=214, Percent_Identity=25.7009345794392, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI20143975, Length=214, Percent_Identity=25.7009345794392, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI46592964, Length=208, Percent_Identity=25.9615384615385, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592915, Length=208, Percent_Identity=25.9615384615385, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592978, Length=208, Percent_Identity=25.9615384615385, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592898, Length=208, Percent_Identity=25.9615384615385, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592956, Length=208, Percent_Identity=25.9615384615385, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592971, Length=208, Percent_Identity=25.9615384615385, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI25914749, Length=203, Percent_Identity=26.6009852216749, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789593, Length=221, Percent_Identity=28.9592760180996, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI87081782, Length=218, Percent_Identity=31.651376146789, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI48994943, Length=223, Percent_Identity=27.8026905829596, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1788761, Length=236, Percent_Identity=26.271186440678, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87081791, Length=226, Percent_Identity=26.9911504424779, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786253, Length=199, Percent_Identity=27.1356783919598, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787029, Length=213, Percent_Identity=24.8826291079812, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786319, Length=215, Percent_Identity=28.3720930232558, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787792, Length=218, Percent_Identity=26.605504587156, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786563, Length=208, Percent_Identity=27.8846153846154, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788225, Length=230, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786345, Length=240, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787164, Length=230, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790162, Length=218, Percent_Identity=26.1467889908257, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789890, Length=210, Percent_Identity=26.1904761904762, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87082268, Length=225, Percent_Identity=25.3333333333333, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1789991, Length=219, Percent_Identity=25.5707762557078, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790190, Length=226, Percent_Identity=26.1061946902655, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788450, Length=213, Percent_Identity=23.4741784037559, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790739, Length=230, Percent_Identity=21.304347826087, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788165, Length=221, Percent_Identity=23.5294117647059, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787112, Length=219, Percent_Identity=26.4840182648402, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1789586, Length=214, Percent_Identity=24.2990654205607, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI2367384, Length=161, Percent_Identity=29.8136645962733, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787712, Length=207, Percent_Identity=28.0193236714976, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787547, Length=233, Percent_Identity=24.0343347639485, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI48995001, Length=217, Percent_Identity=23.963133640553, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790525, Length=229, Percent_Identity=25.3275109170306, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1786872, Length=216, Percent_Identity=27.3148148148148, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1786703, Length=202, Percent_Identity=27.7227722772277, Blast_Score=60, Evalue=9e-11,
Organism=Escherichia coli, GI1790467, Length=216, Percent_Identity=24.0740740740741, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=217, Percent_Identity=31.7972350230415, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71983510, Length=217, Percent_Identity=31.7972350230415, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71983523, Length=217, Percent_Identity=31.7972350230415, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17510237, Length=234, Percent_Identity=28.6324786324786, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17565586, Length=223, Percent_Identity=26.0089686098655, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115533608, Length=204, Percent_Identity=27.9411764705882, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221512771, Length=220, Percent_Identity=30, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24643674, Length=223, Percent_Identity=28.6995515695067, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281362751, Length=228, Percent_Identity=31.5789473684211, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI85725262, Length=183, Percent_Identity=34.4262295081967, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24650855, Length=228, Percent_Identity=31.5789473684211, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24650853, Length=228, Percent_Identity=31.5789473684211, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28574150, Length=241, Percent_Identity=27.8008298755187, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI116007328, Length=241, Percent_Identity=27.8008298755187, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221500365, Length=218, Percent_Identity=28.8990825688073, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI116007184, Length=218, Percent_Identity=28.8990825688073, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24582014, Length=187, Percent_Identity=31.5508021390374, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582012, Length=187, Percent_Identity=31.5508021390374, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24648314, Length=211, Percent_Identity=28.9099526066351, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573571, Length=210, Percent_Identity=27.1428571428571, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24666092, Length=208, Percent_Identity=26.4423076923077, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573573, Length=205, Percent_Identity=27.3170731707317, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28574744, Length=209, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550390, Length=208, Percent_Identity=24.0384615384615, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24650986, Length=215, Percent_Identity=23.7209302325581, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358185, Length=215, Percent_Identity=23.7209302325581, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221460257, Length=206, Percent_Identity=26.6990291262136, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45552359, Length=220, Percent_Identity=28.1818181818182, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45550972, Length=220, Percent_Identity=28.1818181818182, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45552341, Length=220, Percent_Identity=28.1818181818182, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28574259, Length=220, Percent_Identity=25.4545454545455, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45552335, Length=220, Percent_Identity=28.1818181818182, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45552355, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45552363, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45552345, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45552343, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45552339, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45552347, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45552337, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45552357, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45552353, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45552351, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24583969, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45552361, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45552349, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24585091, Length=209, Percent_Identity=22.9665071770335, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62484234, Length=215, Percent_Identity=23.2558139534884, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161077321, Length=212, Percent_Identity=23.1132075471698, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26004; Mature: 26004

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MDKILTCSNLKKGYFNKNALNGLAMEVKKGRIVGLLGPNGSGKTTFLKIAAGILRYSSGE
CCCCCCCCCCCCCCCCCHHHHHHHEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
ILIDGEAPGVNTKAKVAYLPDKNFLYKWMKIKDAIEFYKDFYKDFDEKKCNELLQFMNLD
EEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
KDSKVTSLSKGMLEKLLLTLTLSRKAKLYLLDEPLGGVDPVSRDKILDAIVNNYSEDSTI
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEE
IVTTHLVNDIERIFDDVFFISEGEIALSGIAEELRMEKGMSIDELYKEVFQ
EEEHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MDKILTCSNLKKGYFNKNALNGLAMEVKKGRIVGLLGPNGSGKTTFLKIAAGILRYSSGE
CCCCCCCCCCCCCCCCCHHHHHHHEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
ILIDGEAPGVNTKAKVAYLPDKNFLYKWMKIKDAIEFYKDFYKDFDEKKCNELLQFMNLD
EEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
KDSKVTSLSKGMLEKLLLTLTLSRKAKLYLLDEPLGGVDPVSRDKILDAIVNNYSEDSTI
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEE
IVTTHLVNDIERIFDDVFFISEGEIALSGIAEELRMEKGMSIDELYKEVFQ
EEEHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]