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The map label for this gene is resE [H]

Identifier: 226947490

GI number: 226947490

Start: 307664

End: 308917

Strand: Direct

Name: resE [H]

Synonym: CLM_0324

Alternate gene names: 226947490

Gene position: 307664-308917 (Clockwise)

Preceding gene: 226947489

Following gene: 226947492

Centisome position: 7.4

GC content: 28.63

Gene sequence:

>1254_bases
ATGGAAATCAAAAATAAAATATCAAATGCATACAGTAATAATTCATGGGATAAGAAAGCTATTGAGAACATAGGAACGGA
TGCAATAACTGGAGGATTGCTTATAACAGTTAAAGATAAAAATGATAATATTATATGGAATGCAAGAGAATATGATAATA
TTGTATGTGAAAAGATTTTAAATAAAATTATAGAAAATACTAATAAAGTAAGCCCAGATGTAGATATTAAAAATACATTT
GATAAATTTGACCTAAAACGAGGTGAAGCTCTAATAGGGAAATTAGAAGTTGAGTATATAGGTCCAATTTATTATGAAGA
TTCAGATGTTATATTTTTGAGAATGCTAGACAGAATATTATTTATACTAGGGCTACTATTTTTCATTATATCTATTATAG
TAGGATGGTTATTGTCTTATGCTATCAGTAAACCTATCTTAAAGGTAATAGATGCAACAAATCTTATATCAGAAGGAAAT
TATTCCAAAGGCATAAAAGAAGATTACAGTATATATGAAATCAATAAACTTATAAAATCAATAAATATGATGGCAGGAGA
TTTAGATAAGCAAGAAAAAATAAGACAAGAGCTAACGAAGGATATATCACATGAGCTTAGAACCCCTATAACGACTATGC
AAGCACAACTTGAGGCAATAATGGATGGTCTATGGGAACCATCACAAGAAAGGTTAAAGAGTATATATGATGAACTTCAA
AGATTAAATAGATTAACTGTATCCATAGAGGATTTATCAAGATGTGAGGGCAGTAAACTAAGGCTAAATAAGTCAGAAGT
AGATTTAGAGACTGTAATAACTACAATTTTAACAAATTTTGAAAAGCAGTTATTAGATAAAGATATAAATTTACAAGTAG
ATATTAAACATATTAATATTATGATAGATAAGGATAAAATAAGCCAGGTAATAATTAATATTATCTCAAATGCTATTAAG
TATACTCCAGATAAAGGAGAGATATTTGTTAGGTGTTTTACTAAATCTGATAATGTATATATATCCATAAAAGATAGCGG
AATAGGTATAAGTGATGAAGATAAAGACTATATATTTGAGAGATTTTATAGAACGGATAAGTCAAGGGCTAGAGAGACCG
GAGGAGTTGGGATAGGCCTTACAATATCAAGAGAAATAGTCAAGGCTCATGGTGGCAGTATAAATGTATATAGTAAATTA
GATGAAGGTAGCAACTTCGTAATAAAACTGCCAATAAAGTTTTGTGGGACATAA

Upstream 100 bases:

>100_bases
ATTTTCATTGAGTATCATATTTTTAGCAAACATAGTCAACCATTATTGTATTGAAAAGAAGTTTAATATATATACTAGCG
AAAAAATACAACAGTCGAAA

Downstream 100 bases:

>100_bases
TATTTGAACTTAATTTTTATATCAATCTAGAAGACACTCTTACTTTTGATAGACATGAGTGTCTTTTAAATTTTCAATTT
TATACATTTGAGTCTTTGAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MEIKNKISNAYSNNSWDKKAIENIGTDAITGGLLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSPDVDIKNTF
DKFDLKRGEALIGKLEVEYIGPIYYEDSDVIFLRMLDRILFILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGN
YSKGIKEDYSIYEINKLIKSINMMAGDLDKQEKIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQ
RLNRLTVSIEDLSRCEGSKLRLNKSEVDLETVITTILTNFEKQLLDKDINLQVDIKHINIMIDKDKISQVIINIISNAIK
YTPDKGEIFVRCFTKSDNVYISIKDSGIGISDEDKDYIFERFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKL
DEGSNFVIKLPIKFCGT

Sequences:

>Translated_417_residues
MEIKNKISNAYSNNSWDKKAIENIGTDAITGGLLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSPDVDIKNTF
DKFDLKRGEALIGKLEVEYIGPIYYEDSDVIFLRMLDRILFILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGN
YSKGIKEDYSIYEINKLIKSINMMAGDLDKQEKIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQ
RLNRLTVSIEDLSRCEGSKLRLNKSEVDLETVITTILTNFEKQLLDKDINLQVDIKHINIMIDKDKISQVIINIISNAIK
YTPDKGEIFVRCFTKSDNVYISIKDSGIGISDEDKDYIFERFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKL
DEGSNFVIKLPIKFCGT
>Mature_417_residues
MEIKNKISNAYSNNSWDKKAIENIGTDAITGGLLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSPDVDIKNTF
DKFDLKRGEALIGKLEVEYIGPIYYEDSDVIFLRMLDRILFILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGN
YSKGIKEDYSIYEINKLIKSINMMAGDLDKQEKIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQ
RLNRLTVSIEDLSRCEGSKLRLNKSEVDLETVITTILTNFEKQLLDKDINLQVDIKHINIMIDKDKISQVIINIISNAIK
YTPDKGEIFVRCFTKSDNVYISIKDSGIGISDEDKDYIFERFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKL
DEGSNFVIKLPIKFCGT

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=270, Percent_Identity=30.7407407407407, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=29.6551724137931, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=29.045643153527, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=30.6666666666667, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790346, Length=271, Percent_Identity=29.8892988929889, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789149, Length=331, Percent_Identity=25.9818731117825, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787894, Length=316, Percent_Identity=25.9493670886076, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082128, Length=293, Percent_Identity=26.2798634812287, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=228, Percent_Identity=29.8245614035088, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1788279, Length=294, Percent_Identity=26.530612244898, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081816, Length=339, Percent_Identity=25.0737463126844, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=27.2727272727273, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=27.1653543307087, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=26.1410788381743, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=28.3783783783784, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790861, Length=308, Percent_Identity=24.6753246753247, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789808, Length=296, Percent_Identity=23.6486486486486, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787374, Length=278, Percent_Identity=23.7410071942446, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789403, Length=284, Percent_Identity=23.5915492957746, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790300, Length=237, Percent_Identity=25.7383966244726, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=21.5547703180212, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47577; Mature: 47577

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKNKISNAYSNNSWDKKAIENIGTDAITGGLLITVKDKNDNIIWNAREYDNIVCEKIL
CCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHHH
NKIIENTNKVSPDVDIKNTFDKFDLKRGEALIGKLEVEYIGPIYYEDSDVIFLRMLDRIL
HHHHHCCCCCCCCCCCCCCHHHHHHCCCCHHHEEEEEEEECCEEECCCCCHHHHHHHHHH
FILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
INMMAGDLDKQEKIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RLNRLTVSIEDLSRCEGSKLRLNKSEVDLETVITTILTNFEKQLLDKDINLQVDIKHINI
HHHHHEEEHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEE
MIDKDKISQVIINIISNAIKYTPDKGEIFVRCFTKSDNVYISIKDSGIGISDEDKDYIFE
EEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHH
RFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHCCC
>Mature Secondary Structure
MEIKNKISNAYSNNSWDKKAIENIGTDAITGGLLITVKDKNDNIIWNAREYDNIVCEKIL
CCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHHH
NKIIENTNKVSPDVDIKNTFDKFDLKRGEALIGKLEVEYIGPIYYEDSDVIFLRMLDRIL
HHHHHCCCCCCCCCCCCCCHHHHHHCCCCHHHEEEEEEEECCEEECCCCCHHHHHHHHHH
FILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
INMMAGDLDKQEKIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RLNRLTVSIEDLSRCEGSKLRLNKSEVDLETVITTILTNFEKQLLDKDINLQVDIKHINI
HHHHHEEEHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEE
MIDKDKISQVIINIISNAIKYTPDKGEIFVRCFTKSDNVYISIKDSGIGISDEDKDYIFE
EEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHH
RFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]