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The map label for this gene is tadA [H]

Identifier: 226947243

GI number: 226947243

Start: 31427

End: 31864

Strand: Direct

Name: tadA [H]

Synonym: CLM_0034

Alternate gene names: 226947243

Gene position: 31427-31864 (Clockwise)

Preceding gene: 226947242

Following gene: 226947244

Centisome position: 0.76

GC content: 26.94

Gene sequence:

>438_bases
ATGAATGATTATATAGAATATGCAATAATTGAAGCAAAAAAAGCATTAGCAATAGGAGAAGTACCTGTTGGAGCTATTAT
AGTTAAAGAAAATAAAATTATAGCAAAAAGTCATAATTTAAAAGAGTCATTGAAGGATCCAACAGCTCATGCAGAGATAT
TAGCTATAAAAGAAGCTTGTAATACAATACATAATTGGAGATTAAAAGGATGTAAGATGTATGTAACATTAGAACCATGT
GCTATGTGTGCTAGTGCAATAATTCAATCTAGAATAAGTGAATTGCATATAGGAACCTTTGATCCAGTGGGAGGGGCTTG
TGGGTCAGTAGTAAATATAACAAATAATAGTTATTTAAAAAATAATTTAAATATTAAATGGTTATATGATGATGAATGTA
GTAGAATAATAACAAATTTTTTTAAAAATATTAGATAA

Upstream 100 bases:

>100_bases
TTGATTCTTTATGCAAGGAATCAACATTTGCTTTTATAAATAAAAAAAGGTATAAATAATATTATATAAATAAATAGGTT
CTTATAAAAAGGAGTTTTAT

Downstream 100 bases:

>100_bases
ATATATAAAGGACTTGTAATTAGCAATAATTTTATACAGTAAATGTATTTATTTTAATAAAATTACATTTATTCAAAATA
AATATTATATTAAAGTATTG

Product: cytidine/deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MNDYIEYAIIEAKKALAIGEVPVGAIIVKENKIIAKSHNLKESLKDPTAHAEILAIKEACNTIHNWRLKGCKMYVTLEPC
AMCASAIIQSRISELHIGTFDPVGGACGSVVNITNNSYLKNNLNIKWLYDDECSRIITNFFKNIR

Sequences:

>Translated_145_residues
MNDYIEYAIIEAKKALAIGEVPVGAIIVKENKIIAKSHNLKESLKDPTAHAEILAIKEACNTIHNWRLKGCKMYVTLEPC
AMCASAIIQSRISELHIGTFDPVGGACGSVVNITNNSYLKNNLNIKWLYDDECSRIITNFFKNIR
>Mature_145_residues
MNDYIEYAIIEAKKALAIGEVPVGAIIVKENKIIAKSHNLKESLKDPTAHAEILAIKEACNTIHNWRLKGCKMYVTLEPC
AMCASAIIQSRISELHIGTFDPVGGACGSVVNITNNSYLKNNLNIKWLYDDECSRIITNFFKNIR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=122, Percent_Identity=35.2459016393443, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI145693172, Length=143, Percent_Identity=37.7622377622378, Blast_Score=114, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=42.2680412371134, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17555996, Length=99, Percent_Identity=35.3535353535354, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=29.0540540540541, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16153; Mature: 16153

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDYIEYAIIEAKKALAIGEVPVGAIIVKENKIIAKSHNLKESLKDPTAHAEILAIKEAC
CCCHHHHHHHHHHHHEEECCCCCEEEEEECCEEEECCCCHHHHHCCCCCHHHHHHHHHHH
NTIHNWRLKGCKMYVTLEPCAMCASAIIQSRISELHIGTFDPVGGACGSVVNITNNSYLK
HHHHCCEECCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEE
NNLNIKWLYDDECSRIITNFFKNIR
CCCEEEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNDYIEYAIIEAKKALAIGEVPVGAIIVKENKIIAKSHNLKESLKDPTAHAEILAIKEAC
CCCHHHHHHHHHHHHEEECCCCCEEEEEECCEEEECCCCHHHHHCCCCCHHHHHHHHHHH
NTIHNWRLKGCKMYVTLEPCAMCASAIIQSRISELHIGTFDPVGGACGSVVNITNNSYLK
HHHHCCEECCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEE
NNLNIKWLYDDECSRIITNFFKNIR
CCCEEEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]