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The map label for this gene is livH [H]

Identifier: 226830772

GI number: 226830772

Start: 3025257

End: 3026885

Strand: Direct

Name: livH [H]

Synonym: BURPS1106A_3104

Alternate gene names: 226830772

Gene position: 3025257-3026885 (Clockwise)

Preceding gene: 126453909

Following gene: 126451529

Centisome position: 75.85

GC content: 71.15

Gene sequence:

>1629_bases
ATGCCCATGCCTTTGAGCCGCGCCGCTCGTGCGCTCGCGGCGCTCGCCGCCTGCGCGGCGTTTTCGTTCGCCGCGCCGCG
TGCGGCGCTCGCCGTCACGGCGGCCGACGTCGCCGCGCTCGCCGGCGACGACTTCGATGCGAAGCGCGCCGCGATCGACC
GTCTCGCCGCCGGGCACGACGCCGCCGCGGCCGCGCTGCTGAACGCGCTCGCGAACGGCGACGCGCTCGCGACCGACGCC
GGGCGCATCCTGATTCAGCATGGCGACGCCGCGCGCGACGCACTGACGAACGCGCCCGCGCAGGCGGGCGATGCGCAGCC
GGTGATGCTCAACAACCTGCTGCGCGCGAAGATCGCGAACGCACTGTCGGGGCTCGATCTCGCGTCGCCCGACATCGACA
CGCGCCGCCGCGCGATCGATGCGCTGCTCAAGCGCCCCGATGCCGCGCTCAAGCCGATGATCGACGCCGCGCGTGCGAAG
GAAACCGATCCCGTGCTCAAGCGCCGCCTCGACGCGCTATGGGCGATCGCCGCGCTGCGCGACGCCGATCCCGCGAAGCG
CCTCGAAGCGGTGCGGCTCGTCGCCGCGCGAAGCGATCTCGACATGATCGAGCAACTGCGCCCGCTCGTCGCGAAGCGGC
CCGACGGCGGCGACGCGGAACCCGATGCGCGCGTGCGCGAGGCCGCGCAGCAGGGGCTCGGCGCGCTCTATGCGATCCAG
CGCCGCGGCGAAATCGCGGGCACGCTGTTCGCGGGGCTCTCGCTCGGCAGCGTGCTGCTGCTCGCCGCGCTCGGCCTCGC
GATCACGTACGGCCTCATCGGCGTCATCAACATGGCGCACGGCGAGTTCCTGATGATCGGCGCGTATGCGACCTACGTCG
TGCAGACGCTCGTGCAGCGCTATCTGCCCGGCGCGTTCGACTGGTATCCGCTCGCCGCGATTCCCGTGTCGTTCGCCGCG
GCCGCCGCGCTCGGCATCGTGCTCGAGCGCACGGTGCTCAGGCACCTGTATGGCCGCCCGCTCGAGACGCTGCTCGCGAC
GTTCGGCGTGAGCCTCATCCTGATCCAGGCGACGCGGATGATCTTCGGCGCACAGAACGTGCAGGTCGTCAATCCGTCGT
GGATGAGCGGCGGCGTGACCGTGATGCAGAACCTGATCCTGCCGTACAACCGCCTCGCGATCCTCGCGTTCGCGCTCGTC
GTCGTCGGCATCGCGTGGGCCGTGCTGACGAAAACGCGCCTCGGCCTGTTCGTGCGCGCGGTCACGCAGAACCGCCGGAT
GGCCGCGTGCGTCGGCGTGAAGACGGCGCGCGTCGATTCGTATGCGTTCGCGTTCGGCGCGGGCATCGCGGGCCTCGGCG
GCTGCGCGCTGTCGCAGATCGGCAACGTCGGCCCGGATCTCGGCCAGAGCTACATCGTCGATTCGTTCATGGCGGTCGTG
CTGGGCGGCGTCGGCCAGATCGCGGGCACGGTGCTCGGGGGCTTCGGCCTCGGGCTCGTCAGCAAGGCGATCGAGCCGTT
CTGGGGCGCGGTGCTCGCGAAGATCGCCGTGCTCGTGATGATCGTGCTGTTCATCCAGAAACGCCCGCAAGGGATGTTCG
CCCTGAAGGGCCGCAGCGCGGAGGCATGA

Upstream 100 bases:

>100_bases
GCGCTCGCCTGACGCGCGTGCGGGCGCCGCGCCAGCGCACGGCGTCGCCGTCGCGCGCGTCCGCGCCGCGCGCTTTCTCC
CCTTTCGCGAGGACTGACCG

Downstream 100 bases:

>100_bases
CATGGCTTCGACGATCCATTCCCTTGCCGTCGCGCGCGGCGCGTCGCCCGCTTCGTCCACGGCATCCGCCGCGTCCGCTT
CACCGGCTGCGCCGCGCTTC

Product: putative amino acid ABC transporter, permease protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MPMPLSRAARALAALAACAAFSFAAPRAALAVTAADVAALAGDDFDAKRAAIDRLAAGHDAAAAALLNALANGDALATDA
GRILIQHGDAARDALTNAPAQAGDAQPVMLNNLLRAKIANALSGLDLASPDIDTRRRAIDALLKRPDAALKPMIDAARAK
ETDPVLKRRLDALWAIAALRDADPAKRLEAVRLVAARSDLDMIEQLRPLVAKRPDGGDAEPDARVREAAQQGLGALYAIQ
RRGEIAGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLVQRYLPGAFDWYPLAAIPVSFAA
AAALGIVLERTVLRHLYGRPLETLLATFGVSLILIQATRMIFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALV
VVGIAWAVLTKTRLGLFVRAVTQNRRMAACVGVKTARVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQSYIVDSFMAVV
LGGVGQIAGTVLGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA

Sequences:

>Translated_542_residues
MPMPLSRAARALAALAACAAFSFAAPRAALAVTAADVAALAGDDFDAKRAAIDRLAAGHDAAAAALLNALANGDALATDA
GRILIQHGDAARDALTNAPAQAGDAQPVMLNNLLRAKIANALSGLDLASPDIDTRRRAIDALLKRPDAALKPMIDAARAK
ETDPVLKRRLDALWAIAALRDADPAKRLEAVRLVAARSDLDMIEQLRPLVAKRPDGGDAEPDARVREAAQQGLGALYAIQ
RRGEIAGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLVQRYLPGAFDWYPLAAIPVSFAA
AAALGIVLERTVLRHLYGRPLETLLATFGVSLILIQATRMIFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALV
VVGIAWAVLTKTRLGLFVRAVTQNRRMAACVGVKTARVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQSYIVDSFMAVV
LGGVGQIAGTVLGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA
>Mature_541_residues
PMPLSRAARALAALAACAAFSFAAPRAALAVTAADVAALAGDDFDAKRAAIDRLAAGHDAAAAALLNALANGDALATDAG
RILIQHGDAARDALTNAPAQAGDAQPVMLNNLLRAKIANALSGLDLASPDIDTRRRAIDALLKRPDAALKPMIDAARAKE
TDPVLKRRLDALWAIAALRDADPAKRLEAVRLVAARSDLDMIEQLRPLVAKRPDGGDAEPDARVREAAQQGLGALYAIQR
RGEIAGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLVQRYLPGAFDWYPLAAIPVSFAAA
AALGIVLERTVLRHLYGRPLETLLATFGVSLILIQATRMIFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALVV
VGIAWAVLTKTRLGLFVRAVTQNRRMAACVGVKTARVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQSYIVDSFMAVVL
GGVGQIAGTVLGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=312, Percent_Identity=28.8461538461538, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 56530; Mature: 56399

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMPLSRAARALAALAACAAFSFAAPRAALAVTAADVAALAGDDFDAKRAAIDRLAAGHD
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCH
AAAAALLNALANGDALATDAGRILIQHGDAARDALTNAPAQAGDAQPVMLNNLLRAKIAN
HHHHHHHHHHHCCCCEECCCCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
ALSGLDLASPDIDTRRRAIDALLKRPDAALKPMIDAARAKETDPVLKRRLDALWAIAALR
HHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DADPAKRLEAVRLVAARSDLDMIEQLRPLVAKRPDGGDAEPDARVREAAQQGLGALYAIQ
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHH
RRGEIAGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLVQR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHH
YLPGAFDWYPLAAIPVSFAAAAALGIVLERTVLRHLYGRPLETLLATFGVSLILIQATRM
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALVVVGIAWAVLTKTRLGLFVRA
HHCCCCEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTQNRRMAACVGVKTARVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQSYIVDSFMAVV
HHCCCCHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LGGVGQIAGTVLGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
EA
CC
>Mature Secondary Structure 
PMPLSRAARALAALAACAAFSFAAPRAALAVTAADVAALAGDDFDAKRAAIDRLAAGHD
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCH
AAAAALLNALANGDALATDAGRILIQHGDAARDALTNAPAQAGDAQPVMLNNLLRAKIAN
HHHHHHHHHHHCCCCEECCCCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
ALSGLDLASPDIDTRRRAIDALLKRPDAALKPMIDAARAKETDPVLKRRLDALWAIAALR
HHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DADPAKRLEAVRLVAARSDLDMIEQLRPLVAKRPDGGDAEPDARVREAAQQGLGALYAIQ
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHH
RRGEIAGTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLVQR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHH
YLPGAFDWYPLAAIPVSFAAAAALGIVLERTVLRHLYGRPLETLLATFGVSLILIQATRM
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IFGAQNVQVVNPSWMSGGVTVMQNLILPYNRLAILAFALVVVGIAWAVLTKTRLGLFVRA
HHCCCCEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTQNRRMAACVGVKTARVDSYAFAFGAGIAGLGGCALSQIGNVGPDLGQSYIVDSFMAVV
HHCCCCHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LGGVGQIAGTVLGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
EA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]