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The map label for this gene is secA

Identifier: 226225058

GI number: 226225058

Start: 2560041

End: 2562554

Strand: Reverse

Name: secA

Synonym: Lm4b_02479

Alternate gene names: 226225058

Gene position: 2562554-2560041 (Counterclockwise)

Preceding gene: 226225059

Following gene: 226225057

Centisome position: 87.98

GC content: 38.23

Gene sequence:

>2514_bases
ATGGCTGGACTATTGAAAAAGATTTTTGAATCAGGAAAAAAAGATGTTAAATATTTGGAGAGAAAAGCAGATGAGATTAT
TGCTTTAGCGGATGAAACTGCTGCTCTTTCGGATGATGCTCTACGTGAAAAAACAGTAGAGTTTAAAGAGCGTGTTCAAA
AAGGTGAAACACTGGATGACTTATTGGTAGAAGCATTTGCTGTTGCCAGAGAAGGTGCGAAGCGTGCGCTAGGATTGTAT
CCATTTAAAGTTCAATTAATGGGTGGGATTGTTCTCCACGAAGGTAACATTGCAGAGATGAAAACTGGTGAAGGTAAAAC
GTTAACAGCGACACTACCAGTTTATTTAAACGCGCTTTCTGGTGAAGGTGTGCATGTTGTTACAGTCAACGAATACTTAG
CTCATCGTGATGCTGAAGAAATGGGCGTTTTATACAATTTCCTTGGACTTTCTGTAGGGCTAAACCTAAATGCTTTATCG
AGCACAGAAAAACGAGAAGCTTATGCATGTGATATTACGTATAGCACAAATAATGAATTAGGATTTGACTATTTACGTGA
TAATATGGTTGTTTACAAAGAAGAAATGGTACAACGTCCGCTAGCTTTTGCTGTTATCGATGAAGTCGATTCCATTTTGG
TCGATGAAGCGAGAACACCATTAATTATTTCTGGTGAAGCAGAAAAATCGACTATTCTATATGTGCGTGCAAATACTTTT
GTCCGTACTCTTACAGAAGAGGAAGATTATACAGTTGATATTAAAACAAAATCTGTTCAATTAACCGAAGATGGTATGAC
AAAAGGAGAAAACTACTTTGATGTAGAGAACCTTTTTGATTTGGAAAATACCGTAATTTTACATCATATTGCTCAAGCGT
TAAAAGCTAACTATACAATGAGCCTAGATGTCGATTATGTTGTTCAAGATGATGAAGTATTAATCGTTGACCAATTCACT
GGTCGTATTATGAAAGGTCGTCGTTTCAGTGAAGGTTTACACCAAGCGCTTGAAGCAAAAGAAGGCGTAACTATTCAAAA
CGAATCCAAAACAATGGCGACAATTACATTCCAAAACTATTTCCGTATGTATAAAAAACTTGCAGGGATGACGGGTACTG
CAAAAACGGAAGAAGAAGAGTTCCGCGATATTTATAATATGCGCGTTATTGAAATTCCAACTAATAAAGTAATTATTCGT
GATGACCGTCCTGATTTAATTTACACAACGATTGAAGCGAAATTTAATGCAGTGGTAGAAGATATCGCCGAACGTCATGC
AAAAGGACAACCCGTATTAGTCGGTACAGTTGCGATTGAAACATCCGAACTTATTTCTAGCAAATTAAAACGCAAAGGAA
TTAAGCATGATGTACTAAACGCGAAGCAACATGAACGTGAAGCTGATATCATTAAACATGCAGGTGAACGTGGCGCGGTA
GTAATCGCAACCAACATGGCTGGTCGTGGTACGGATATCAAACTTGGTGAGGGTACGATTGAAGCTGGAGGTTTAGCAGT
TATTGGTACAGAACGTCATGAATCACGTCGTATAGATAACCAATTACGTGGTCGTTCTGGACGTCAAGGAGACCCTGGTG
TGACTCAATTTTATCTTTCTATGGAAGATGAATTGATGCGTCGTTTCGGTTCAGACAATATGAAATCAATGATGGAACGC
TTTGGTATGGCAGAAGATGCTATCCAAAGTAAAATGGTTAGTCGTGCAGTTGAATCCGCACAAAGACGTGTGGAAGGAAA
TAACTTTGATTCCCGGAAACAAGTTTTACAATATGATGATGTACTTCGCCAACAACGGGAAGTTATCTATAAACAGCGTT
ATGAAGTAATTAATGCAGAAAACAGTTTGCGTGAAATTATTGAACAAATGATTCAACGTACGGTCAACTTTATCGTTTCT
AGTAATGCATCAAGCCATGAACCTGAAGAAGCTTGGAATCTACAAGGAATTATCGACTATGTGGATGCGAACTTACTTCC
TGAAGGCACTATCACACTAGAAGATCTACAAAATAGAACAAGCGAAGATATTCAAAATCTAATTTTAGATAAAATCAAAG
CGGCTTACGACGAAAAAGAAACACTACTACCTCCAGAAGAATTTAACGAATTCGAAAAAGTAGTATTGCTTCGTGTTGTT
GATACTAAATGGGTTGATCATATTGATGCCATGGATCATTTACGTGACGGTATTCATTTACGTGCGTACGGTCAAATTGA
TCCGCTTCGTGAGTATCAATCAGAAGGCTTTGAAATGTTTGAAGCAATGGTATCGTCCATTGATGAAGATGTTTCTCGTT
ATATTATGAAAGCAGAAATTCGCCAAAACCTTGAACGTGAGCAAGTTGCCAAAGGGGAAGCAATTAATCCTGCTGAAGGT
AAACCAGAAGCGAAACGCCAACCAATCCGCAAAGATCAACACATTGGACGTAATGATCCATGCCCATGTGGTAGCGGCAA
AAAATATAAAAATTGTCACGGTAAAGAAGCATAG

Upstream 100 bases:

>100_bases
AGTGATAGAATTAGTTTGTATATTTAAGTGAAGATAATTCCTGAAAGTTATTATAGATGAAACTGCGCGATGACAGCGAA
AACAGTAGAGGAGAATTTAA

Downstream 100 bases:

>100_bases
ATTGAAACAATTTAAAAAGCGCCTGAAAGACGGCGCTTTTTGCTATGAAAGTTTATAAGTAAATTTAAAAAAGGTGGAAT
TAGAATGGAATTAGCAGAAA

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 837; Mature: 836

Protein sequence:

>837_residues
MAGLLKKIFESGKKDVKYLERKADEIIALADETAALSDDALREKTVEFKERVQKGETLDDLLVEAFAVAREGAKRALGLY
PFKVQLMGGIVLHEGNIAEMKTGEGKTLTATLPVYLNALSGEGVHVVTVNEYLAHRDAEEMGVLYNFLGLSVGLNLNALS
STEKREAYACDITYSTNNELGFDYLRDNMVVYKEEMVQRPLAFAVIDEVDSILVDEARTPLIISGEAEKSTILYVRANTF
VRTLTEEEDYTVDIKTKSVQLTEDGMTKGENYFDVENLFDLENTVILHHIAQALKANYTMSLDVDYVVQDDEVLIVDQFT
GRIMKGRRFSEGLHQALEAKEGVTIQNESKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFRDIYNMRVIEIPTNKVIIR
DDRPDLIYTTIEAKFNAVVEDIAERHAKGQPVLVGTVAIETSELISSKLKRKGIKHDVLNAKQHEREADIIKHAGERGAV
VIATNMAGRGTDIKLGEGTIEAGGLAVIGTERHESRRIDNQLRGRSGRQGDPGVTQFYLSMEDELMRRFGSDNMKSMMER
FGMAEDAIQSKMVSRAVESAQRRVEGNNFDSRKQVLQYDDVLRQQREVIYKQRYEVINAENSLREIIEQMIQRTVNFIVS
SNASSHEPEEAWNLQGIIDYVDANLLPEGTITLEDLQNRTSEDIQNLILDKIKAAYDEKETLLPPEEFNEFEKVVLLRVV
DTKWVDHIDAMDHLRDGIHLRAYGQIDPLREYQSEGFEMFEAMVSSIDEDVSRYIMKAEIRQNLEREQVAKGEAINPAEG
KPEAKRQPIRKDQHIGRNDPCPCGSGKKYKNCHGKEA

Sequences:

>Translated_837_residues
MAGLLKKIFESGKKDVKYLERKADEIIALADETAALSDDALREKTVEFKERVQKGETLDDLLVEAFAVAREGAKRALGLY
PFKVQLMGGIVLHEGNIAEMKTGEGKTLTATLPVYLNALSGEGVHVVTVNEYLAHRDAEEMGVLYNFLGLSVGLNLNALS
STEKREAYACDITYSTNNELGFDYLRDNMVVYKEEMVQRPLAFAVIDEVDSILVDEARTPLIISGEAEKSTILYVRANTF
VRTLTEEEDYTVDIKTKSVQLTEDGMTKGENYFDVENLFDLENTVILHHIAQALKANYTMSLDVDYVVQDDEVLIVDQFT
GRIMKGRRFSEGLHQALEAKEGVTIQNESKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFRDIYNMRVIEIPTNKVIIR
DDRPDLIYTTIEAKFNAVVEDIAERHAKGQPVLVGTVAIETSELISSKLKRKGIKHDVLNAKQHEREADIIKHAGERGAV
VIATNMAGRGTDIKLGEGTIEAGGLAVIGTERHESRRIDNQLRGRSGRQGDPGVTQFYLSMEDELMRRFGSDNMKSMMER
FGMAEDAIQSKMVSRAVESAQRRVEGNNFDSRKQVLQYDDVLRQQREVIYKQRYEVINAENSLREIIEQMIQRTVNFIVS
SNASSHEPEEAWNLQGIIDYVDANLLPEGTITLEDLQNRTSEDIQNLILDKIKAAYDEKETLLPPEEFNEFEKVVLLRVV
DTKWVDHIDAMDHLRDGIHLRAYGQIDPLREYQSEGFEMFEAMVSSIDEDVSRYIMKAEIRQNLEREQVAKGEAINPAEG
KPEAKRQPIRKDQHIGRNDPCPCGSGKKYKNCHGKEA
>Mature_836_residues
AGLLKKIFESGKKDVKYLERKADEIIALADETAALSDDALREKTVEFKERVQKGETLDDLLVEAFAVAREGAKRALGLYP
FKVQLMGGIVLHEGNIAEMKTGEGKTLTATLPVYLNALSGEGVHVVTVNEYLAHRDAEEMGVLYNFLGLSVGLNLNALSS
TEKREAYACDITYSTNNELGFDYLRDNMVVYKEEMVQRPLAFAVIDEVDSILVDEARTPLIISGEAEKSTILYVRANTFV
RTLTEEEDYTVDIKTKSVQLTEDGMTKGENYFDVENLFDLENTVILHHIAQALKANYTMSLDVDYVVQDDEVLIVDQFTG
RIMKGRRFSEGLHQALEAKEGVTIQNESKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFRDIYNMRVIEIPTNKVIIRD
DRPDLIYTTIEAKFNAVVEDIAERHAKGQPVLVGTVAIETSELISSKLKRKGIKHDVLNAKQHEREADIIKHAGERGAVV
IATNMAGRGTDIKLGEGTIEAGGLAVIGTERHESRRIDNQLRGRSGRQGDPGVTQFYLSMEDELMRRFGSDNMKSMMERF
GMAEDAIQSKMVSRAVESAQRRVEGNNFDSRKQVLQYDDVLRQQREVIYKQRYEVINAENSLREIIEQMIQRTVNFIVSS
NASSHEPEEAWNLQGIIDYVDANLLPEGTITLEDLQNRTSEDIQNLILDKIKAAYDEKETLLPPEEFNEFEKVVLLRVVD
TKWVDHIDAMDHLRDGIHLRAYGQIDPLREYQSEGFEMFEAMVSSIDEDVSRYIMKAEIRQNLEREQVAKGEAINPAEGK
PEAKRQPIRKDQHIGRNDPCPCGSGKKYKNCHGKEA

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=900, Percent_Identity=48.1111111111111, Blast_Score=813, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 94676; Mature: 94545

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLLKKIFESGKKDVKYLERKADEIIALADETAALSDDALREKTVEFKERVQKGETLDD
CCHHHHHHHHCCHHHHHHHHHHHHHEEEECCCHHHCCHHHHHHHHHHHHHHHHCCCCHHH
LLVEAFAVAREGAKRALGLYPFKVQLMGGIVLHEGNIAEMKTGEGKTLTATLPVYLNALS
HHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCEEEEECCCCCEEEEEHHHHHHHCC
GEGVHVVTVNEYLAHRDAEEMGVLYNFLGLSVGLNLNALSSTEKREAYACDITYSTNNEL
CCCEEEEEHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCC
GFDYLRDNMVVYKEEMVQRPLAFAVIDEVDSILVDEARTPLIISGEAEKSTILYVRANTF
CHHHHHCCEEEEHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCHH
VRTLTEEEDYTVDIKTKSVQLTEDGMTKGENYFDVENLFDLENTVILHHIAQALKANYTM
HHHHCCCCCEEEEEEECEEEEECCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCEE
SLDVDYVVQDDEVLIVDQFTGRIMKGRRFSEGLHQALEAKEGVTIQNESKTMATITFQNY
EEEEEEEEECCCEEEEECHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCEEEEEEHHHH
FRMYKKLAGMTGTAKTEEEEFRDIYNMRVIEIPTNKVIIRDDRPDLIYTTIEAKFNAVVE
HHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEECCCEEEEECCCCCEEEEEHHHHHHHHHH
DIAERHAKGQPVLVGTVAIETSELISSKLKRKGIKHDVLNAKQHEREADIIKHAGERGAV
HHHHHHCCCCCEEEEEEEECHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCCEE
VIATNMAGRGTDIKLGEGTIEAGGLAVIGTERHESRRIDNQLRGRSGRQGDPGVTQFYLS
EEEECCCCCCCEEEECCCEECCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEC
MEDELMRRFGSDNMKSMMERFGMAEDAIQSKMVSRAVESAQRRVEGNNFDSRKQVLQYDD
HHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VLRQQREVIYKQRYEVINAENSLREIIEQMIQRTVNFIVSSNASSHEPEEAWNLQGIIDY
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHH
VDANLLPEGTITLEDLQNRTSEDIQNLILDKIKAAYDEKETLLPPEEFNEFEKVVLLRVV
HCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
DTKWVDHIDAMDHLRDGIHLRAYGQIDPLREYQSEGFEMFEAMVSSIDEDVSRYIMKAEI
HHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQNLEREQVAKGEAINPAEGKPEAKRQPIRKDQHIGRNDPCPCGSGKKYKNCHGKEA
HHCCCHHHHHCCCCCCCCCCCCHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AGLLKKIFESGKKDVKYLERKADEIIALADETAALSDDALREKTVEFKERVQKGETLDD
CHHHHHHHHCCHHHHHHHHHHHHHEEEECCCHHHCCHHHHHHHHHHHHHHHHCCCCHHH
LLVEAFAVAREGAKRALGLYPFKVQLMGGIVLHEGNIAEMKTGEGKTLTATLPVYLNALS
HHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCEEEEECCCCCEEEEEHHHHHHHCC
GEGVHVVTVNEYLAHRDAEEMGVLYNFLGLSVGLNLNALSSTEKREAYACDITYSTNNEL
CCCEEEEEHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCC
GFDYLRDNMVVYKEEMVQRPLAFAVIDEVDSILVDEARTPLIISGEAEKSTILYVRANTF
CHHHHHCCEEEEHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCHH
VRTLTEEEDYTVDIKTKSVQLTEDGMTKGENYFDVENLFDLENTVILHHIAQALKANYTM
HHHHCCCCCEEEEEEECEEEEECCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCEE
SLDVDYVVQDDEVLIVDQFTGRIMKGRRFSEGLHQALEAKEGVTIQNESKTMATITFQNY
EEEEEEEEECCCEEEEECHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCEEEEEEHHHH
FRMYKKLAGMTGTAKTEEEEFRDIYNMRVIEIPTNKVIIRDDRPDLIYTTIEAKFNAVVE
HHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEECCCEEEEECCCCCEEEEEHHHHHHHHHH
DIAERHAKGQPVLVGTVAIETSELISSKLKRKGIKHDVLNAKQHEREADIIKHAGERGAV
HHHHHHCCCCCEEEEEEEECHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCCEE
VIATNMAGRGTDIKLGEGTIEAGGLAVIGTERHESRRIDNQLRGRSGRQGDPGVTQFYLS
EEEECCCCCCCEEEECCCEECCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEC
MEDELMRRFGSDNMKSMMERFGMAEDAIQSKMVSRAVESAQRRVEGNNFDSRKQVLQYDD
HHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VLRQQREVIYKQRYEVINAENSLREIIEQMIQRTVNFIVSSNASSHEPEEAWNLQGIIDY
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHH
VDANLLPEGTITLEDLQNRTSEDIQNLILDKIKAAYDEKETLLPPEEFNEFEKVVLLRVV
HCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
DTKWVDHIDAMDHLRDGIHLRAYGQIDPLREYQSEGFEMFEAMVSSIDEDVSRYIMKAEI
HHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQNLEREQVAKGEAINPAEGKPEAKRQPIRKDQHIGRNDPCPCGSGKKYKNCHGKEA
HHCCCHHHHHCCCCCCCCCCCCHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]