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The map label for this gene is czrA [H]

Identifier: 226225041

GI number: 226225041

Start: 2541853

End: 2542158

Strand: Reverse

Name: czrA [H]

Synonym: Lm4b_02462

Alternate gene names: 226225041

Gene position: 2542158-2541853 (Counterclockwise)

Preceding gene: 226225042

Following gene: 226225040

Centisome position: 87.28

GC content: 38.24

Gene sequence:

>306_bases
ATGGAAAACGCAAAACAATCTTTAGATGAAGAAACGCTATTTAGTGTTACGCAGATATTTAAGGCGCTTTCTGATCCAAC
GCGTGTGCAGATTTTAAATTTGCTTCAAGACCGCGAATACTCTGTGAATGAAATTGCGCGAACACTTGCGTTTAACCAGA
CAACTGTTTCTCACCAGCTGCGTTTTTTAAAAAACTTAAGACTTGTGAAATCAAGACGTGAAGGCACGACGATTTATTAT
ATGCAAGATGATAATCACGTATTAGAATTACTCACACAAGCAATTCGCCACGTGCACCATCATTAA

Upstream 100 bases:

>100_bases
TAATCATTTTTTAATAGATGTGTTGTTAAACTTGCGGAATCATTCCTATTTAAGTATCATATGAGTATATGAACATATAT
GGAAAATGGAGTGATATTTA

Downstream 100 bases:

>100_bases
GTAAGAACGCTCAGAAAACCTTTTAGGAATGATGGGTGTTTTTTATCCCAAATAAACAGAGATTATGGTAAAGTAAGTAA
CAAATAAAAGCTTGGAGGAA

Product: transcription regulator ArsR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MENAKQSLDEETLFSVTQIFKALSDPTRVQILNLLQDREYSVNEIARTLAFNQTTVSHQLRFLKNLRLVKSRREGTTIYY
MQDDNHVLELLTQAIRHVHHH

Sequences:

>Translated_101_residues
MENAKQSLDEETLFSVTQIFKALSDPTRVQILNLLQDREYSVNEIARTLAFNQTTVSHQLRFLKNLRLVKSRREGTTIYY
MQDDNHVLELLTQAIRHVHHH
>Mature_101_residues
MENAKQSLDEETLFSVTQIFKALSDPTRVQILNLLQDREYSVNEIARTLAFNQTTVSHQLRFLKNLRLVKSRREGTTIYY
MQDDNHVLELLTQAIRHVHHH

Specific function: Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11919; Mature: 11919

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENAKQSLDEETLFSVTQIFKALSDPTRVQILNLLQDREYSVNEIARTLAFNQTTVSHQL
CCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHH
RFLKNLRLVKSRREGTTIYYMQDDNHVLELLTQAIRHVHHH
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MENAKQSLDEETLFSVTQIFKALSDPTRVQILNLLQDREYSVNEIARTLAFNQTTVSHQL
CCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHH
RFLKNLRLVKSRREGTTIYYMQDDNHVLELLTQAIRHVHHH
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]